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In conversation with Fortune Editor-in-Chief Alyson Shontell, as well as Alphabet President and Chief Investment Officer Ruth Porat and Barclays Group CEO C.S. Venkatakrishnan, Al-Falih described what he sees as a world where “everyone is concerned” about supply chains still “pushed to the limit,” more than five years after the onset of the pandemic. “Supply chain resilience for both companies and nations and policy makers and governments is dominant,” he said, also citing digital disruption as a key inflection point.

“Underneath this,” Minister Al-Falih told Shontell, there’s a human concern he sees driving leaders’ actions today: “I believe people are looking for partners with whom they can trust who are not short-term, transactional.” The minister framed Saudi Arabia’s Vision 2030 not simply as a national reform agenda, but as a blueprint for global collaboration rooted in mutual resilience — the belief that long-term prosperity depends on shared growth across nations and industries.​

“Interdependence remains the defining truth of our time,” Minister Al-Falih said in his opening remarks, urging businesses to embrace cross-border partnerships rather than retreat behind protectionist walls. He described the Kingdom as a “platform for global growth,” emphasizing that resilience in the modern economy requires openness, innovation, and integration with like-minded partners. His message was clear: Saudi Arabia aims to be the world’s most reliable investment destination for companies navigating geopolitical fractures, shifting supply chains, and the green transition.​

A decade of transformation

Since its launch in 2016 under Crown Prince Mohammed bin Salman, Vision 2030 has redrawn Saudi Arabia’s economic map. The minister highlighted that non-oil sectors now account for 56% of the national GDP, up from 40% at the program’s inception. Unemployment has dropped below 7% while women’s participation in the labor force has more than doubled to 37% (the latest World Bank data shows 34%), far surpassing early reform targets.​

Saudi Arabia’s capital markets, now ranked among the world’s top 10, have become a magnet for international investors, highlighted by the blockbuster IPO of national champion oil firm Saudi Aramco in 2019, now ranked among the top 10 most valuable companies in the world—and the most profitable company ever as of 2023. Multinational companies are establishing regional headquarters in Riyadh at an accelerated pace, Minister Al-Falih noted: 675 as of this year, already exceeding Vision 2030’s target of 500 by 2030. The minister praised these developments as proof that structural change, once theoretical, is now an engine of global competitiveness.​

From oil superpower to clean energy leader

Minister Al-Falih also repositioned Saudi Arabia’s traditional role in global energy markets. Long a linchpin of oil and gas supply, the Kingdom now seeks to be just as dominant in renewables — from solar and wind to green hydrogen. “Our ambition is to enable the industries of the future to flourish,” he said, pointing to plans that leverage both the Kingdom’s vast natural resources and rapidly growing renewable portfolio.​

He underscored that Saudi Arabia’s competitive edge — low energy costs, geographic centrality, and expanding data infrastructure — makes it ideal for energy-intensive industries, from AI and cloud computing to advanced manufacturing. Riyadh, he announced, is already emerging as a leading global hub for data centers, gaming, and e-sports.​

In his closing remarks, Minister Al-Falih invited global companies to “discover for themselves” the ambition and capacity driving Saudi Arabia’s transformation. The nation’s investment strategy, he argued, rests on three pillars — competitiveness, connectivity, and capability — each supported by world-class infrastructure and regulatory modernization.​

Saudi Arabia’s evolving identity as both a reformer and a reliable partner resonates far beyond the Gulf. In an era when multinationals are diversifying away from single-market dependencies, Minister Al-Falih’s remarks made clear that Riyadh wants to anchor that shift — offering predictability, efficiency, and partnership in a volatile world.

Speaking alongside Saudi Arabia’s Minister of Investment, Khalid Al-Falih, and Barclays Group CEO C.S. Venkatakrishnan, Porat painted a sweeping vision of AI’s economic, social, and scientific potential, highlighting how many Nobel prize-winners she is fortunate to work alongside at Alphabet. She framed artificial intelligence not merely as a technological advance, but as a transformative force capable of reshaping entire industries, powering economic growth, and driving human progress at an unprecedented pace.

Porat said “people are playing” with AI through chatbots, and that is “great, because that gets you on the journey. But then the question is: what does it mean for my country? What does it mean for my business?” She argued that it’s underappreciated how “we’re already living” through significant breakthroughs in health and science.

Could AI cure cancer?

Porat pointed to breakthroughs in health care as proof of AI’s broader promise. She highlighted DeepMind’s AlphaFold, which maps protein structures in 3D, noting it has been described as “the greatest contribution to drug discovery in our lifetime.” The open-source project has been used by millions of scientists in more than 190 countries, accelerating research into diseases previously considered intractable.

She also said significant work is being done on early diagnosis of diseases. “We all know early diagnosis can be the difference between survival or not or how difficult the course of treatment is.” In cancer, for instance, that comes in seeing metastatic cells early enough to treat the disease before it spreads. This is very much the proverbial “finding the needle in the haystack,” she said, likening its application to cybersecurity and finding malicious code.

“We should be able to cure cancer in our lifetime,” Porat asserted, calling AI a key driver of scientific discovery. She spoke of early cancer detection, AI-powered cybersecurity defenses that identify threats before they occur, and productivity gains that free workers “from the administrative tasks that take us away from what matters most.”

Balancing speed and responsibility

Porat and Venkatakrishnan both discussed how the moment demands urgency from governments and businesses alike. “Every head of state I meet,” Porat explained, “wants to be part of this digital transformation.” She pointed to staggering potential economic benefits, noting that estimates show AI could unlock a $200 billion GDP boost for Saudi Arabia and “trillions globally.” But unlocking that value, she argued, will require serious investment in both energy and infrastructure.

In the United States, for example, she said simply modernizing the electrical grid could create 100 gigawatts of unused capacity, a figure backed up by independent research. She said the power is effectively sitting there, “waiting to be connected.” Another bottleneck is a lack of talent in the form of the blue-collar trades, specifically electricians, Porat noted, echoing other Fortune 500 leaders such as Ford CEO Jim Farley. Google, she added, is investing in training programs for electricians as part of its workforce initiatives, acknowledging that technological progress only matters if societies prepare workers to participate in it. “There are jobs that come in trades as well as the outside across business.”

Venkatakrishnan discussed the “huge amount of investment, hundreds of billions if not trillions happening all over the world.” He impliclitly acknowledged discussions about a potential bubble in AI infrastructure, saying that “in all large capital-investment cycles, there will be some misallocation, some misinvestment. It’s always true. And I think that’s important for people to guard against.” He argued that, whether the demand turns out to be 1x or 5x of a certain projection, investing in infrastructure—and by extension the tradesmen who build and run it—is a wise choice. Venkatakrishnan added that major capital cycles also require partners you can trust and “who are there for the long term and who will help you through the teething troubles.”

Her message echoed themes of inclusion and global partnership that ran throughout the panel, particularly as Saudi Arabia positions itself as a regional hub for digital infrastructure and AI investment. Al-Falih emphasized his country’s long-term strategy of building supply chain resilience and energy capacity to power the digital economy of the future.

Porat closed by urging leaders to really dig in and reimagine what’s possible in their own organizations. The transformative potential of this technology, she said, lies not only in boosting productivity but in elevating human creativity and purpose.