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Real-World Outcomes From Third-Line SCLC Treatment Show Need for More Options
small cell lung cancer (ES-SCLC) see little benefit from third-line (3L) therapies, according to a new analysis of real-world outcomes.1 The authors of the analysis say it underscores the “urgent” need for novel… -

Should Zimmer Biomet’s AI-Powered Orthopedic Robotics Launch Prompt Action From ZBH Investors?
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Earlier this week, Zimmer Biomet Holdings showcased its latest orthopedic robotics and digital health innovations, including FDA-cleared mBos TKA System and the recently acquired Monogram Technologies robotic platform, at the annual meeting of the American Association of Hip and Knee Surgeons.
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A standout revelation was the integration of AI-driven and autonomous technologies into the company’s expanding knee and hip portfolios, reflecting Zimmer Biomet’s commitment to advancing surgical precision and connected care solutions.
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We’ll examine how Zimmer Biomet’s integration of AI-driven orthopedic robotics could reshape the long-term outlook for its investment narrative.
Trump has pledged to “unleash” American oil and gas and these 22 US stocks have developments that are poised to benefit.
To be a shareholder in Zimmer Biomet, you need to believe in the power of innovation in orthopedic robotics and digital health to drive demand for advanced surgical solutions. This week’s showcase of FDA-cleared and AI-powered products could energize sentiment but is unlikely to meaningfully shift the company’s near-term reliance on successful product launches; ongoing industry pricing pressures still remain the key headwind.
Among the latest announcements, the FDA clearance of the mBos TKA System stands out for its relevance, as it highlights Zimmer Biomet’s efforts to keep pace in the competitive race for autonomous robotics and supports the company’s narrative of product-driven growth, even as full regulatory approvals for other key technologies remain pending.
In contrast, investors should be aware of increasing pricing pressures and the consequences if these persist through…
Read the full narrative on Zimmer Biomet Holdings (it’s free!)
Zimmer Biomet Holdings is projected to reach $9.2 billion in revenue and $1.3 billion in earnings by 2028. This outlook assumes a 5.5% annual revenue growth rate and an earnings increase of about $476 million from the current $823.5 million.
Uncover how Zimmer Biomet Holdings’ forecasts yield a $110.92 fair value, a 8% upside to its current price.
ZBH Community Fair Values as at Oct 2025 Simply Wall St Community members estimate fair value for Zimmer Biomet anywhere between US$95 and US$167.48 per share, with three unique perspectives. As these opinions range widely, consider the risk of ongoing pricing pressures that could challenge margin recovery and ultimately affect future earnings.
Explore 3 other fair value estimates on Zimmer Biomet Holdings – why the stock might be worth 8% less than the current price!
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Vaisala (HLSE:VAIAS) Earnings Beat 5-Year Trend, Margin Gains Reinforce Bullish Narratives
Vaisala Oyj (HLSE:VAIAS) delivered another robust earnings performance, with profits expanding at 16.7% over the past year and a five-year compound annual growth rate of 12.8%. The company’s net profit margin rose to 10.9% from last year’s 10.1%, underscoring improved efficiency. Revenue growth of 6.1% per year continues to outpace the broader Finnish market. With forward earnings growth projected at 13.8% per year and no notable risks flagged, investors are likely to focus on the momentum in margins and the sustainability of this positive trend.
See our full analysis for Vaisala Oyj.
Next up, we’ll put the latest numbers head-to-head with the current narratives, breaking down where sentiment aligns with the data and where surprises might emerge.
See what the community is saying about Vaisala Oyj
HLSE:VAIAS Earnings & Revenue History as at Oct 2025 -
Vaisala’s current share price of €44.95 trades below its DCF fair value estimate of €49.76, signaling about an 11% discount to modeled intrinsic worth.
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According to analysts’ consensus view, broader value discussions also reference a Price-To-Earnings ratio of 25.7x. This is just below the European Electronic industry average of 26x and above the peer group’s 21.4x.
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This sector-relative valuation is seen as reasonable, especially since earnings have expanded by 12.8% per year over the past five years. Consensus believes this trend supports the view that Vaisala’s quality and growth justifies its mild premium to local peers.
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At the same time, consensus highlights potential upside, noting the current share price remains 17.3% below the latest analyst price target of €53.60.
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See what else analysts are tracking in Vaisala’s growth and value story: 📊 Read the full Vaisala Oyj Consensus Narrative.
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Rapid growth in digital services, such as subscription-based offerings, has driven segment-level sales expansion. Recurring software revenues (e.g., Xweather) saw 53% year-on-year growth, raising hopes for additional gross margin upside as these higher-margin business lines scale.
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Consensus narrative spotlights diversification into digital and industrial segments as a catalyst for dependable, broad-based margin growth.
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With analysts forecasting profit margins to rise from 10.9% to 12.3% over three years, the consensus story emphasizes these gains could make earnings quality more resilient, especially as digitalization and R&D outlays underpin proprietary advantages for Vaisala.
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This long-term thesis leans on proven agility in managing price increases and coping with tariff impacts, providing some protection in an unpredictable environment.
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Mounira Al Solh: Nassib’s Bakery—Distributing Warmth – Announcements
Kunsthuis SYB is excited to introduce Nassib’s Bakery: Distributing Warmth, a project initiated by Mounira Al Solh, transforming SYB’s front room into a saj bakery this fall.
Nassib’s Bakery: Distributing Warmth is a re-enactment and…
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Ferrari SC40 revives the spirit of the F40 with a modern, hybrid twist
- The Ferrari SC40 is a one-off berlinetta based on the 296 GTB, producing 610kW and 740Nm of torque.
- Its design pays tribute to the 1987 F40, featuring angular geometry and a fixed rear wing.
- Carbon-Kevlar elements and hybrid V6 tech link the…
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Metropolitan Bank Holding (MCB) Net Margin Rises, Reinforcing Bullish Valuation Narrative
Metropolitan Bank Holding (MCB) delivered net profit margins of 24.3%, up from last year’s 23.1%, with average annual earnings growth of 7.6% over the past five years. This year’s 6.5% earnings growth trails the longer-term average, but analysts see a sharp acceleration ahead. They forecast 28.7% annual earnings growth and 18.4% annual revenue growth, both well above the US market. At $70.9, shares trade considerably below some fair value estimates, adding to the positive sentiment around the company’s high-quality earnings and strong value positioning.
See our full analysis for Metropolitan Bank Holding.
The next step unpacks how these figures compare with the market’s prevailing narratives, highlighting where consensus is confirmed and where surprises may lie.
See what the community is saying about Metropolitan Bank Holding
NYSE:MCB Earnings & Revenue History as at Oct 2025 -
Net profit margins expanded to 24.3%, up from 23.1% last year, building on a consistently strong five-year track record.
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Analysts’ consensus view holds that margin expansion is being driven by investments in technology and fee-based income streams,
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The consensus narrative notes these tech and fintech partnerships are already supporting stable funding, which helps boost profitability in markets like New York City.
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Analysts also point out that prudent risk management and diversified loan portfolios have contributed to earnings durability by limiting credit risk and supporting margins versus peers.
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To see how analysts’ consensus aligns with deeper margin trends and future expectations, check out the full story for Metropolitan Bank Holding. 📊 Read the full Metropolitan Bank Holding Consensus Narrative.
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Earnings are projected to grow 28.7% per year and revenue 18.4% per year, both far above the US market averages of 15.5% and 10% respectively.
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Analysts’ consensus view emphasizes that these growth projections depend on continuing digital transformation and low-cost deposit growth,
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The narrative highlights that successful integration of an advanced tech stack and growth in core deposit verticals are expected to underpin higher noninterest income and expanded lending for the next several years.
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However, they acknowledge risks such as delays in tech upgrades or increased deposit competition, which could pressure both margins and growth if not managed carefully.
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Shares trade at $70.90, creating a wide gap versus the DCF fair value estimate of $151.56 and the peer price-to-earnings average of 18x, with Metropolitan at just 11.6x.
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Analysts’ consensus narrative describes this valuation as reflecting both the company’s profitable growth and some caution around concentration risks,
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The below-fair-value price aligns with the company’s strong earnings quality and long-term digital growth opportunities, according to consensus forecasts.
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Still, the narrative weighs risks like reliance on commercial real estate and regulatory scrutiny, which could explain why the market offers such a substantial discount to estimated fair value.
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Scientists discover a hidden gene mutation that causes deafness—and a way to fix it
Mutations in a gene called CPD have been found to play a key role in a rare inherited form of hearing loss, according to an international research collaboration. Scientists from the University of Chicago, the University of Miami, and several…
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Scientists discover a hidden gene mutation that causes deafness—and a way to fix it
Mutations in a gene called CPD have been found to play a key role in a rare inherited form of hearing loss, according to an international research collaboration. Scientists from the University of Chicago, the University of Miami, and several…
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Yahoo ist Teil der Yahoo-Markenfamilie.
Yahoo ist Teil der Yahoo Markenfamilie.
Bei der Nutzung unserer Websites und Apps verwenden wir Cookie-Richtlinie.”>Cookies, um:…
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Thames Water paid £20mn to cover KKR’s due diligence for abortive bid
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Roula Khalaf, Editor of the FT, selects her favourite stories in this weekly newsletter.
Near-bankrupt Thames Water paid £20mn to cover the due diligence costs of KKR for its abortive attempt to rescue the UK’s largest water utility.
Thames Water selected KKR, the private equity giant, as its preferred bidder for an emergency rescue earlier this year. Thames Water was obliged to pay for the cost to potential buyers of assessing and researching the state of the utility’s infrastructure, operations and finances under the terms of the deal. The cost of that exercise topped £20mn, according to people familiar with the situation, largely due to fees paid to KKR’s advisers.
KKR pulled out of the deal in June, citing the risk of government intervention. It then passed its due diligence to lenders that are now trying to win approval from regulators for their own takeover of Thames Water, which provides water and sewerage services to about 16mn customers. Any deal will also need to be approved by London’s High Court.
The fees will raise concerns that cash is leaking out of the utility, which receives all of its income from customer water bills. Thames Water is struggling under the weight of £20bn debt and is trying to avoid temporary renationalisation under the government’s special administration regime after its previous owners — a clutch of pension and sovereign wealth funds — wrote off their investments and walked away from the business in 2024.
The scale of the due diligence effort, which included site visits to water and waste treatment facilities, was borne from the poor visibility Thames Water has over the state of its crumbling infrastructure, with documents revealing last year that the utility has failed to map almost a third of its sewage pipe network.
Reports produced by KKR and the creditors underscored the dangers of so-called “single point of failure risk” at some of Thames Water’s biggest sites, according to people familiar with the matter and documents seen by the Financial Times.
Beckton sewage works, which KKR and Thames Water creditor analysis suggests is at risk of failure © Jeff Gilbert/Alamy Coppermills water treatment works and Beckton sewage treatment works in East London were identified as the two facilities at the highest risk of outages, according to this analysis.
The cost of the due diligence work has added to a multimillion pound fee bonanza for advisers, bankers and lawyers trying to secure the financial future of the troubled company. The total advisory bill could top £200mn a debt restructuring is agreed, the High Court heard earlier this year; costs that the utility itself is covering from its own cash-strapped balance sheet.
KKR’s advisers on its abandoned bid included investment bank PJT Partners, law firm Kirkland & Ellis and management consultant Roland Berger.
Had KKR completed its rescue of Thames Water, the private equity firm would have covered the costs of its due diligence, according to a person familiar with the situation.
The senior creditors — which include US investment firms Elliott Management and Apollo Global Management — submitted their latest rescue proposal to regulator Ofwat earlier this month, pledging £3.15bn in equity and a 25 per cent writedown of the nominal value of their exposure.
They have also asked for concessions on regulatory fines and targets. The creditors said they had “an ambition” to reduce sewage outflows by 30 per cent by 2030, well below the government’s target of 50 per cent.
Rival potential buyers including CK Infrastructure, owner of Northumbrian Water, have recently written to Ofwat claiming they have been “excluded” from the bidding process meaning it was unlikely to get the best deal for customers. CKI has indicated it would bid for Thames Water if the government puts it into its SAR.
The creditors said their plan “will see £20.5bn invested over the next five years and is the fastest and most reliable route to turn around Thames Water, deliver on customer priorities, clean up waterways and rebuild public trust.”
KKR declined to comment on its due diligence costs.
Thames Water said: “Advisor fees are part of an extensive, complex recapitalisation; customers will not pay for these fees. We remain focused on securing a market-led recapitalisation that establishes the financial and regulatory foundations required to support the investment and performance improvements our customers expect and return the company to a stable financial foundation.”
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