EACS 2025 was an essential meeting for the numerous presentations about PrEP that included far more than news about injectable formulations, which for all their promise, are still hardly used by anyone.
Cabotegravir-LA (CAB-LA) and lenacapavir…
Microsoft Corp. once again surpassed $4 trillion in valuation, joining artificial intelligence chipmaker Nvidia in the exclusive club that also briefly included Apple on Tuesday. The sky-high valuations highlight the investor frenzy around artificial intelligence.
Earlier in the day, OpenAI said it has reorganized its ownership structure and converted its business into a public benefit corporation after two crucial regulators, the Delaware and California attorneys general, said they would not oppose the plan. It also said has signed a new agreement with its longtime backer Microsoft that gives the software giant a roughly 27% stake in OpenAI’s new for-profit corporation.
The news gave Microsoft’s shares a boost as the stock closed up 2% at $542.07, valuing the technology giant at $4.04 trillion. Microsoft’s valuation previously passed $4 trillion in July, making it the second company after Nvidia to reach the milestone.
Apple’s shares, meanwhile, crossed the $4 trillion line earlier Tuesday before closing up slightly at $269 and a total valuation of $3.99 trillion. Thanks to the iPhone’s success, Apple was the the first publicly traded company to valued at $1 trillion, $2 trillion and eventually, $3 trillion.
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The company that formed…
Future iPhones may not have physical buttons, according to an unconfirmed report from a leaker who goes by Instant Digital, and who shared the information on the Chinese social media platform Weibo.
Tech news site 9to5Mac translated the post…
Mount Fuji and the Shinjuku skyline in Tokyo, Japan, on Friday, Feb. 14, 2025. Photographer: Kiyoshi Ota/Bloomberg via Getty Images
Bloomberg | Bloomberg | Getty Images
Asia-Pacific markets were set for a higher open Wednesday as investors awaited the Federal Reserve’s interest rate decision, widely believed to bring a second straight 25 basis point cut.
Markets are assigning a nearly 100% probability that another quarter-point reduction, on the heels of September’s cut, would bring the federal funds rate to a range between 3.75%-4.00%.
“If [Fed chair Jerome Powell] comes off dovish, bets for future Fed cuts will increase and provide more fuel to market momentum,” veteran investor Louis Navellier wrote in a daily note.
The federal funds rate, set by the Federal Open Market Committee, is the interest rate banks charge each other for overnight loans. While it doesn’t directly affect consumers, the Fed’s moves often influence borrowing costs for mortgages, credit cards and other loans.
Japan’s Nikkei 225 futures pointed to a stronger open, with the contract in Chicago at 50,745 and its counterpart in Osaka at 50,660, compared to the previous close of 50,219.18.
Australia’s S&P/ASX 200 started the day flat.
Hong Kong markets are closed for the holidays.
Overnight in the U.S., all three major averages closed higher. The S&P 500 rose 0.23% to close at 6,890.89. It had surpassed the 6,900 level for the first time on an intraday basis earlier in the day.
The Nasdaq Composite advanced 0.80% to finish at 23,827.49, while the Dow Jones Industrial Average gained 161.78 points, or 0.34%, to settle at 47,706.37. In addition to their closing highs, the tech-heavy Nasdaq and 30-stock Dow scored new all-time intraday highs alongside the broad market S&P 500.
—CNBC’s Jeff Cox, Sean Conlon and Pia Singh contributed to this report.
PARIS, October 27, 2025 — More than 60% of HIV diagnoses among migrants in Switzerland occur after arrival, with some groups waiting up to 6 years before detection; findings that expose significant gaps in the country’s prevention and…
Blasts have been reported in Gaza after Israel’s prime minister Benjamin Netanyahu ordered his military to carry out “powerful” air strikes.
Witnesses said they saw explosions and heard tank fire in Gaza City and Deir al Balah.
An…
Meet Fernanda Maldonado, Principal Planning & Technical in our Non-Operated Joint Ventures team. As a fourth-generation mining engineer, mining runs deep in her family – nearly 100 years of history.
Since joining BHP seven years ago, Fernanda has worked across regions from the Ecuadorian jungle to remote Canada, discovering the global impact of mining and the role BHP plays in shaping its future.
“I can only imagine my great-grandfather digging rocks in a remote polymetallic mine in Andean Peru back in the 20´s being told his great granddaughter was not only working in mining but also part of the biggest mining company in the world!”
Fernanda is proud to be part of a company that provides resources to develop the world and the investments that help build communities around it.
Our 140th anniversary is not just a celebration of the past; it’s a launchpad for the future. We’re investing in the resources, relationships, and innovations that will shape a more sustainable and inclusive world.
Each chapter in the BHP story is driven by meeting the changing needs of the world.
But it’s the character of our people that will continue to make all the difference.
TL;DR: Upgrade any computer with this Microsoft Office 2024 Home and Business for Mac or PC license, now on sale for $179.99 (reg. $249.99).
Don’t let the PC crowd have all the fun. Mac users can…
