US President Donald Trump on Monday praised India and Prime Minister Narendra Modi without naming him, saying “India is a great country with a good friend of mine at the top”.
Trump, addressing a summit of world leaders at this Egyptian city…
US President Donald Trump on Monday praised India and Prime Minister Narendra Modi without naming him, saying “India is a great country with a good friend of mine at the top”.
Trump, addressing a summit of world leaders at this Egyptian city…
The study included a total of 996 participants with varied demographic and health-related characteristics. Most participants were young adults aged 18–29 years (69.1%), followed by 17.7% aged 30–39. The gender…
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Reference…
Zoe Saldaña wants audiences to truly understand the skill and talent that go into motion capture performances, like in James Cameron‘s Avatar movies.
The Oscar-winning actress shared during a recent interview with Alicia Keys for Beyond…
The Steelie Awards recognise member companies for their contribution to the steel industry over a one-year period. The selection process for the shortlist varies between awards. In most cases the submissions are requested via the appropriate worldsteel committee. Entries are then judged by selected independent expert panels. The winners and judges for each award are listed below.
EMSTEEL – Pioneering low-carbon steel: EMSTEEL’s multi-lever net-zero strategy
Judges:
InfraBuild – SENSE 600: Innovative lower-embodied carbon reinforcing steel solution
Judges:
Ternium – Winds of change: Ternium’s first step into renewable energy in Argentina
Judges:
HBIS Group Co., Ltd. – “LCA+Life Well-Being Index” Collaborative Evaluation System: Innovating to driving marketing and application of metal decorative products.
Judges:
ArcelorMittal – Integration of army veterans and supporting the families of fallen employees
Judges:
ArcelorMittal – The Paris 2024 Olympic and Paralympic Games
Judges:
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Notes
The World Steel Association (worldsteel) is one of the largest and most dynamic industry associations in the world, with members in every major steel-producing country. worldsteel represents steel producers, national and regional steel industry associations, and steel research institutes. Members represent around 85% of global steel production.
New research has shown, for the first time, how mixtures of commonly used medications which end up in our waterways and natural environments might increase the development of antibiotic resistant bacteria.
When humans or animals take…
October 14, 2025
KATHMANDU – At least four people died and 5,874 others have been infected with dengue virus that has spread to 75 districts of the country since January.
Both deaths and infections recorded so far are fewer compared to previous…
A tiny molecule called a nanobody may succeed where today’s cancer drugs often fail, according to University of Hawaiʻi at Mānoa researcher Stefan Moisyadi, who has been refining the concept for nearly a decade.
“Antibodies won the Nobel Prize for immunotherapy,” said Moisyadi, a scientist at the Yanagimachi Institute for Biogenesis Research at the John A. Burns School of Medicine (JABSOM). “They work in some cancers, but not all. In colorectal cancer, they hardly work at all. But when we used nanobodies, bingo, it worked.”
The study, published in eGastroenterology, shows how Moisyadi and his team from JABSOM, the UH Cancer Center, and the College of Tropical Agriculture and Human Resilience used mRNA (messenger ribonucleic acid) to make the body produce nanobodies that block PD-L1—a molecule that helps tumors hide from the immune system. By stopping PD-L1, nanobodies allow immune cells to recognize and attack cancer.
Nanobodies are about one-tenth the size of regular antibodies, cheaper to make, and more resilient under stress, according to the research.
“They don’t trigger an immune response in the patient,” Moisyadi said. “They penetrate better because they’re small. They can even refold back to their original shape when conditions improve. Basically, they’re indestructible—they work much better and they’re cheaper.”
Basically, they’re indestructible—they work much better and they’re cheaper.
—Stefan Moisyadi
While traditional antibody treatments can cost patients more than $200,000 a year, nanobody therapy—delivered as mRNA, similar to the COVID-19 vaccines—could cost only a fraction of that, making it far more accessible to patients.
“People can’t afford antibody treatments,” Moisyadi said. “Here we make an RNA version. The patient’s own cells turn it into a protein… It goes into the circulation, finds the tumor, and blocks PD-L1.”
In mouse studies, the treatment cut tumor growth by about 50%—a major result for a cancer that rarely responds to immunotherapy.
Now collaborating with the University of Maryland, Baltimore County, Moisyadi hopes to see this breakthrough continue growing from its roots in Hawaiʻi.
“This works,” he said. “We have the chance to be on the cutting edge. We need to have leaders’ buy-in because everyone here is still focused on antibodies.”
Read more at JABSOM