Blog

  • Radiomics on Spinal Cord MRI May Offer Superior MS Assessment

    Radiomics on Spinal Cord MRI May Offer Superior MS Assessment

    Radiomics may offer a superior means to assess spinal cord pathology compared with visual assessment of MRI in patients with multiple sclerosis (MS), a new report found.

    The findings may make it easier for clinicians to more precisely understand…

    Continue Reading

  • Timing is everything: a simple chemical method to determine the bioavailable surface concentration of insecticide for insecticide-treated net evaluation | Malaria Journal

    Timing is everything: a simple chemical method to determine the bioavailable surface concentration of insecticide for insecticide-treated net evaluation | Malaria Journal

    All tests were conducted at Biolytrics Vietnam between September 2018 and June 2020. Five experiments were performed. (1) validation of the GC-FID (Gas Chromatography with Flame Ionization Detection) compared to standard CIPAC HPLC (High…

    Continue Reading

  • eNAMPT/TLR4 signaling drives PAH cellular phenotypic switching and lung vascular remodeling | Cell Communication and Signaling

    eNAMPT/TLR4 signaling drives PAH cellular phenotypic switching and lung vascular remodeling | Cell Communication and Signaling

  • Ahmed M, Zaghloul N, Zimmerman P, Casanova NG, Sun X, Reyes Hernon V, et al. Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb. Pulm Circ. 2021;11(4):20458940211059712.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Chen J, Sysol JR, Singla S, Zhao S, Yamamura A, Valdez-Jasso D, et al. Nicotinamide phosphoribosyltransferase promotes pulmonary vascular remodeling and is a therapeutic target in pulmonary arterial hypertension. Circulation. 2017;135(16):1532–46.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Sun X, Sun BL, Babicheva A, Vanderpool R, Oita RC, Casanova N, et al. Direct extracellular NAMPT involvement in pulmonary hypertension and vascular remodeling. Transcriptional regulation by SOX and HIF-2alpha. Am J Respir Cell Mol Biol. 2020;63(1):92–103.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Gorelova A, Berman M, Al Ghouleh I. Endothelial-to-mesenchymal transition in pulmonary arterial hypertension. Antioxid Redox Signal. 2021;34(12):891–914.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Pillai VB, Sundaresan NR, Kim G, Samant S, Moreno-Vinasco L, Garcia JG, et al. Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling. Am J Physiol Heart Circ Physiol. 2013;304(3):H415-26.

    CAS 
    PubMed 

    Google Scholar 

  • Oita RC, Camp SM, Ma W, Ceco E, Harbeck M, Singleton P, et al. Novel mechanism for nicotinamide phosphoribosyltransferase Inhibition of TNF-alpha-mediated apoptosis in human lung endothelial cells. Am J Respir Cell Mol Biol. 2018;59(1):36–44.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Casanova NG, Herazo-Maya J, Kempf CL, Sun BL, Song JH, Hernandez A et al. eNAMPT is a novel DAMP and therapeutic target in human and murine pulmonary fibrosis. . Am J Respir Cell Mol Biol. 2025.

  • Quijada H, Bermudez T, Kempf CL, Valera DG, Garcia AN, Camp SM et al. Endothelial eNAMPT amplifies preclinical acute lung injury: efficacy of an eNAMPT-Neutralising mAb. Eur Respir J. 2021;57(5):2002536.

  • Bao C, Liang S, Han Y, Yang Z, Liu S, Sun Y, et al. The novel lysosomal autophagy inhibitor (ROC-325) ameliorates experimental pulmonary hypertension. Hypertension. 2023;80(1):70–83.

    CAS 
    PubMed 

    Google Scholar 

  • Tang C, Luo Y, Li S, Huang B, Xu S, Li L. Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats. Biomed Pharmacother. 2021;133:111081.

    CAS 
    PubMed 

    Google Scholar 

  • Moreno-Vinasco L, Gomberg-Maitland M, Maitland ML, Desai AA, Singleton PA, Sammani S, et al. Genomic assessment of a multikinase inhibitor, sorafenib, in a rodent model of pulmonary hypertension. Physiol Genomics. 2008;33(2):278–91.

    CAS 
    PubMed 

    Google Scholar 

  • Tang H, Babicheva A, McDermott KM, Gu Y, Ayon RJ, Song S, et al. Endothelial HIF-2alpha contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition. Am J Physiol Lung Cell Mol Physiol. 2018;314(2):L256–75.

    PubMed 

    Google Scholar 

  • Guo M, Morley MP, Jiang C, Wu Y, Li G, Du Y, et al. Guided construction of single cell reference for human and mouse lung. Nat Commun. 2023;14(1):4566.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Tsukui T, Sun KH, Wetter JB, Wilson-Kanamori JR, Hazelwood LA, Henderson NC, et al. Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis. Nat Commun. 2020;11(1):1920.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Pertea M, Kim D, Pertea GM, Leek JT, Salzberg SL. Transcript-level expression analysis of RNA-seq experiments with HISAT, stringtie and ballgown. Nat Protoc. 2016;11(9):1650–67.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Miller SA, Policastro RA, Sriramkumar S, Lai T, Huntington TD, Ladaika CA, et al. LSD1 and aberrant DNA methylation mediate persistence of enteroendocrine progenitors that support BRAF-mutant colorectal cancer. Cancer Res. 2021;81(14):3791–805.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Gillich A, Zhang F, Farmer CG, Travaglini KJ, Tan SY, Gu M, et al. Capillary cell-type specialization in the alveolus. Nature. 2020;586(7831):785–9.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Liu B, Yi D, Xia X, Ramirez K, Zhao H, Cao Y, et al. General capillary endothelial cells undergo reprogramming into arterial endothelial cells in pulmonary hypertension through HIF-2alpha/Notch4 pathway. Circulation. 2024;150(5):414–7.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Man S, Sanchez Duffhues G, Ten Dijke P, Baker D. The therapeutic potential of targeting the endothelial-to-mesenchymal transition. Angiogenesis. 2019;22(1):3–13.

    CAS 
    PubMed 

    Google Scholar 

  • Hong J, Arneson D, Umar S, Ruffenach G, Cunningham CM, Ahn IS, et al. Single-cell study of two rat models of pulmonary arterial hypertension reveals connections to human pathobiology and drug repositioning. Am J Respir Crit Care Med. 2021;203(8):1006–22.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Tarhan L, Bistline J, Chang J, Galloway B, Hanna E, Weitz E. Single cell portal: an interactive home for single-cell genomics data. bioRxiv. 2023. https://doi.org/10.1101/2023.07.13.548886.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Rabinovitch M, Guignabert C, Humbert M, Nicolls MR. Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension. Circ Res. 2014;115(1):165–75.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Ahmed M, Casanova NG, Zaghloul N, Gupta A, Rodriguez M, Robbins IR, et al. The eNAMPT/TLR4 inflammatory cascade drives the severity of intra-amniotic inflammation in pregnancy and predicts infant outcomes. Front Physiol. 2023;14:1129413.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Bime C, Casanova NG, Nikolich-Zugich J, Knox KS, Camp SM, Garcia JGN. Strategies to dampen COVID-19-mediated lung and systemic inflammation and vascular injury. Transl Res. 2021;232:374–8. https://doi.org/10.1016/j.trsl.2020.12.008.

  • Gao L, Ramirez FJ, Cabrera JTO, Varghese MV, Watanabe M, Tsuji-Hosokawa A, et al. eNAMPT is a novel therapeutic target for mitigation of coronary microvascular disease in type 2 diabetes. Diabetologia. 2024;67(9):1998–2011.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Sun BL, Sun X, Casanova N, Garcia AN, Oita R, Algotar AM, et al. Role of secreted extracellular nicotinamide phosphoribosyltransferase (eNAMPT) in prostate cancer progression: novel biomarker and therapeutic target. EBioMedicine. 2020;61:103059.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Sun BL, Sun X, Kempf CL, Song JH, Casanova NG, Camp SM, et al. Involvement of eNAMPT/TLR4 inflammatory signaling in progression of non-alcoholic fatty liver disease, steatohepatitis, and fibrosis. FASEB J. 2023;37(3):e22825.

    CAS 
    PubMed 

    Google Scholar 

  • Tumurkhuu G, Casanova NG, Kempf CL, Ercan Laguna D, Camp SM, Dagvadorj J, et al. eNAMPT/TLR4 inflammatory cascade activation is a key contributor to SLE lung vasculitis and alveolar hemorrhage. J Transl Autoimmun. 2023;6:100181.

    CAS 
    PubMed 

    Google Scholar 

  • Ye SQ, Simon BA, Maloney JP, Zambelli-Weiner A, Gao L, Grant A, et al. Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. Am J Respir Crit Care Med. 2005;171(4):361–70.

    PubMed 

    Google Scholar 

  • Alvandi Z, Bischoff J. Endothelial-mesenchymal transition in cardiovascular disease. Arterioscler Thromb Vasc Biol. 2021;41(9):2357–69.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Huang J, Pu Y, Zhang H, Xie L, He L, Zhang CL, et al. KLF2 mediates the suppressive effect of laminar flow on vascular calcification by inhibiting endothelial BMP/SMAD1/5 signaling. Circ Res. 2021;129(4):e87-100.

    CAS 
    PubMed 

    Google Scholar 

  • Kang K, Xiang J, Zhang X, Xie Y, Zhou M, Zeng L, et al. N6-methyladenosine modification of KLF2 may contribute to endothelial-to-mesenchymal transition in pulmonary hypertension. Cell Mol Biol Lett. 2024;29(1):69.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Zhang-Sun ZY, Xu XZ, Escames G, Lei WR, Zhao L, Zhou YZ, et al. Targeting NR1D1 in organ injury: challenges and prospects. Mil Med Res. 2023;10(1):62.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Chae WJ, Bothwell ALM. Canonical and non-canonical Wnt signaling in immune cells. Trends Immunol. 2018;39(10):830–47.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Sun L, Xing J, Zhou X, Song X, Gao S. Wnt/beta-catenin signalling, epithelial-mesenchymal transition and crosslink signalling in colorectal cancer cells. Biomed Pharmacother. 2024;175:116685.

    CAS 
    PubMed 

    Google Scholar 

  • Tang H, Wu K, Wang J, Vinjamuri S, Gu Y, Song S, et al. Pathogenic role of mTORC1 and mTORC2 in pulmonary hypertension. JACC Basic Transl Sci. 2018;3(6):744–62.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Lowe M, Lage J, Paatela E, Munson D, Hostager R, Yuan C, et al. Cry2 is critical for circadian regulation of myogenic differentiation by Bclaf1-mediated mRNA stabilization of Cyclin D1 and Tmem176b. Cell Rep. 2018;22(8):2118–32.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Bryant AJ, Ebrahimi E, Nguyen A, Wolff CA, Gumz ML, Liu AC, Esser KA. A wrinkle in time: circadian biology in pulmonary vascular health and disease. Am J Physiol Lung Cell Mol Physiol. 2022;322(1):L84–101.

    CAS 
    PubMed 

    Google Scholar 

  • Lopez-Moncada F, Torres MJ, Lavanderos B, Cerda O, Castellon EA, Contreras HR. SPARC induces E-Cadherin repression and enhances cell migration through integrin alphavbeta3 and the transcription factor ZEB1 in prostate cancer cells. Int J Mol Sci. 2022;23(11):5874. https://doi.org/10.3390/ijms23115874.

  • Dean A, Gregorc T, Docherty CK, Harvey KY, Nilsen M, Morrell NW, et al. Role of the aryl hydrocarbon receptor in Sugen 5416-induced experimental pulmonary hypertension. Am J Respir Cell Mol Biol. 2018;58(3):320–30.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Liang S, Guo H, Ma K, Li X, Wu D, Wang Y, et al. A PLCB1-PI3K-AKT signaling axis activates EMT to promote cholangiocarcinoma progression. Cancer Res. 2021;81(23):5889–903.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Karoor V, Fini MA, Loomis Z, Sullivan T, Hersh LB, Gerasimovskaya E, et al. Sustained activation of Rho GTPases promotes a synthetic pulmonary artery smooth muscle cell phenotype in Neprilysin null mice. Arterioscler Thromb Vasc Biol. 2018;38(1):154–63.

    CAS 
    PubMed 

    Google Scholar 

  • Alexander MR, Murgai M, Moehle CW, Owens GK. Interleukin-1beta modulates smooth muscle cell phenotype to a distinct inflammatory state relative to PDGF-DD via NF-kappaB-dependent mechanisms. Physiol Genomics. 2012;44(7):417–29.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Cho DI, Ahn MJ, Cho HH, Cho M, Jun JH, Kang BG, et al. Angptl4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulation. Exp Mol Med. 2023;55(2):426–42.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Cheung AK, Ko JM, Lung HL, Chan KW, Stanbridge EJ, Zabarovsky E, et al. Cysteine-rich intestinal protein 2 (CRIP2) acts as a repressor of NF-kappaB-mediated proangiogenic cytokine transcription to suppress tumorigenesis and angiogenesis. Proc Natl Acad Sci U S A. 2011;108(20):8390–5.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Yang L, Zhou F, Zheng D, Wang D, Li X, Zhao C, Huang X. FGF/FGFR signaling: from lung development to respiratory diseases. Cytokine Growth Factor Rev. 2021;62:94–104.

    CAS 
    PubMed 

    Google Scholar 

  • Wen Z, Jiang L, Yu F, Xu X, Chen M, Li C, et al. ScrNA-seq reveals NAMPT-mediated macrophage polarization shapes smooth muscle cell plasticity in pulmonary arterial hypertension. Interdiscip Med. 2024;2(4):e20240016.

    CAS 

    Google Scholar 

  • Streef TJ, Groeneveld EJ, van Herwaarden T, Hjortnaes J, Goumans MJ, Smits AM. Single-cell analysis of human fetal epicardium reveals its cellular composition and identifies CRIP1 as a modulator of EMT. Stem Cell Reports. 2023;18(7):1421–35.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Ahmed MN, Zhang Y, Codipilly C, Zaghloul N, Patel D, Wolin M, Miller EJ. Extracellular superoxide dismutase overexpression can reverse the course of hypoxia-induced pulmonary hypertension. Mol Med. 2012;18:38–46.

    CAS 
    PubMed 

    Google Scholar 

  • Tarazona S, Furio-Tari P, Turra D, Pietro AD, Nueda MJ, Ferrer A, et al. Data quality aware analysis of differential expression in RNA-seq with NOIseq r/bioc package. Nucleic Acids Res. 2015;43(21):e140.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Zawia A, Arnold ND, West L, Pickworth JA, Turton H, Iremonger J, et al. Altered macrophage polarization induces experimental pulmonary hypertension and is observed in patients with pulmonary arterial hypertension. Arterioscler Thromb Vasc Biol. 2021;41(1):430–45.

    CAS 
    PubMed 

    Google Scholar 

  • Qiu H, He Y, Ouyang F, Jiang P, Guo S, Guo Y. The role of regulatory T cells in pulmonary arterial hypertension. J Am Heart Assoc. 2019;8(23):e014201.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Rodriguez M, Xu H, Hernandez A, Ingraham J, Canizales Galaviz J, Teran Arce F et al. NEDD4 E3 ligase-catalyzed NAMPT ubiquitination and autophagy are essential for pyroptosis-independent NAMPT secretion in human monocytes. Cell Commun Signal. 2025;23:157 https://doi.org/10.1186/s12964-025-02164-5.

  • Audrito V, Serra S, Brusa D, Mazzola F, Arruga F, Vaisitti T, et al. Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia. Blood. 2015;125(1):111–23.

    CAS 
    PubMed 

    Google Scholar 

  • Wang Z, Li W, Chen S, Tang XX. Role of ADAM and ADAMTS proteases in pathological tissue remodeling. Cell Death Discov. 2023;9(1):447.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Hudalla H, Michael Z, Christodoulou N, Willis GR, Fernandez-Gonzalez A, Filatava EJ, et al. Carbonic anhydrase inhibition ameliorates inflammation and experimental pulmonary hypertension. Am J Respir Cell Mol Biol. 2019;61(4):512–24.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Zhu Y, Dun H, Ye L, Terada Y, Shriver LP, Patti GJ et al. Targeting fatty acid beta-oxidation impairs monocyte differentiation and prolongs heart allograft survival. JCI Insight. 2022;7(7):e151596. https://doi.org/10.1172/jci.insight.151596.

  • Tyrrell C, De Cecco M, Reynolds NL, Kilanowski F, Campopiano D, Barran P, et al. Isoleucine/leucine2 is essential for chemoattractant activity of beta-defensin Defb14 through chemokine receptor 6. Mol Immunol. 2010;47(6):1378–82.

    CAS 
    PubMed 

    Google Scholar 

  • Cai X, Deng J, Ming Q, Cai H, Chen Z. Chemokine-like factor 1: a promising therapeutic target in human diseases. Exp Biol Med (Maywood). 2020;245(16):1518–28.

    CAS 
    PubMed 

    Google Scholar 

  • Liao Y, Deng C, Wang X. VSIG4 ameliorates intestinal inflammation through inhibiting macrophages NLRP3 inflammasome and pyroptosis. Tissue Cell. 2024;86:102285.

    CAS 
    PubMed 

    Google Scholar 

  • Li R, Chen B, Kubota A, Hanna A, Humeres C, Hernandez SC, et al. Protective effects of macrophage-specific integrin alpha5 in myocardial infarction are associated with accentuated angiogenesis. Nat Commun. 2023;14(1):7555.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Jairath V, Acosta Felquer ML, Cho RJ. IL-23 inhibition for chronic inflammatory disease. Lancet. 2024;404(10463):1679–92.

    CAS 
    PubMed 

    Google Scholar 

  • Tang C, Chen S, Qian H, Huang W. Interleukin-23: as a drug target for autoimmune inflammatory diseases. Immunology. 2012;135(2):112–24.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Garcia AN, Casanova NG, Valera DG, Sun X, Song JH, Kempf CL, et al. Involvement of eNAMPT/TLR4 signaling in murine radiation pneumonitis: protection by eNAMPT neutralization. Transl Res. 2022;239:44–57.

    CAS 
    PubMed 

    Google Scholar 

  • Hassoun PM, Mouthon L, Barbera JA, Eddahibi S, Flores SC, Grimminger F, et al. Inflammation, growth factors, and pulmonary vascular remodeling. J Am Coll Cardiol. 2009;54(1 Suppl):S10–9.

    CAS 
    PubMed 

    Google Scholar 

  • Pullamsetti SS, Savai R, Janssen W, Dahal BK, Seeger W, Grimminger F, et al. Inflammation, immunological reaction and role of infection in pulmonary hypertension. Clin Microbiol Infect. 2011;17(1):7–14.

    CAS 
    PubMed 

    Google Scholar 

  • Soon E, Holmes AM, Treacy CM, Doughty NJ, Southgate L, Machado RD, et al. Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension. Circulation. 2010;122(9):920–7.

    CAS 
    PubMed 

    Google Scholar 

  • Wang J, Tian XT, Peng Z, Li WQ, Cao YY, Li Y, Li XH. HMGB1/TLR4 promotes hypoxic pulmonary hypertension via suppressing BMPR2 signaling. Vascul Pharmacol. 2019;117:35–44.

    CAS 
    PubMed 

    Google Scholar 

  • Xiao G, Zhuang W, Wang T, Lian G, Luo L, Ye C, et al. Transcriptomic analysis identifies toll-like and nod-like pathways and necroptosis in pulmonary arterial hypertension. J Cell Mol Med. 2020;24(19):11409–21.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Young KC, Hussein SM, Dadiz R, deMello D, Devia C, Hehre D, et al. Toll-like receptor 4-deficient mice are resistant to chronic hypoxia-induced pulmonary hypertension. Exp Lung Res. 2010;36(2):111–9.

    CAS 
    PubMed 

    Google Scholar 

  • Dai Z, Li M, Wharton J, Zhu MM, Zhao YY. Prolyl-4 hydroxylase 2 (PHD2) deficiency in endothelial cells and hematopoietic cells induces obliterative vascular remodeling and severe pulmonary arterial hypertension in mice and humans through hypoxia-inducible factor-2alpha. Circulation. 2016;133(24):2447–58.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

Continue Reading

  • Looking at the roles genes play in the growth and aging of tomatoes

    Looking at the roles genes play in the growth and aging of tomatoes

    Overexpressing these receptors caused ABA hypersensitivity, dwarfism, delayed senescence, reproductive anomalies, and enhanced fruit pigmentation. The findings reveal how ABA signaling integrates hormonal crosstalk to fine-tune…

    Continue Reading

  • Just a moment…

    Just a moment…

    Continue Reading

  • Samsung Unveils Real QLED Technology, Setting a New Global Standard for Picture Quality and Sustainability

    Samsung Unveils Real QLED Technology, Setting a New Global Standard for Picture Quality and Sustainability

    This certification confirms that Samsung’s QLED TVs meet the International Electrotechnical Commission (IEC) 62595-1-6 standard, ensuring the use of genuine Quantum Dot…

    Continue Reading

  • Bavarian Nordic Announces Major Shareholder Notification

    Bavarian Nordic Announces Major Shareholder Notification

    COPENHAGEN, Denmark, October 29, 2025 – Pursuant to section 30 of the Danish Capital Markets Act, Bavarian Nordic A/S hereby announces that the Company has received notification from Morgan Stanley that they hold 5.20% of the shares and voting…

    Continue Reading

  • Over 400 items from Gene Hackman’s estate up for auction | Gene Hackman

    Over 400 items from Gene Hackman’s estate up for auction | Gene Hackman

    Busts by Rodin and works by Kandinksy and Matisse are among some 400 items belonging to the late actor going up for auction next month.

    Three Golden Globe statues, a variety of film memorabilia and annotated scripts, posters and an easel are also…

    Continue Reading

  • Galaxy S26 Rumor Roundup: Samsung May Be Shaking Up Its Lineup

    Galaxy S26 Rumor Roundup: Samsung May Be Shaking Up Its Lineup

    We’re likely only a few months away from the next Samsung Unpacked event and rumors are swirling about the Galaxy S26 line of phones. And boy, have they been all over the place. A few months ago, there was talk that Samsung would be replacing its…

    Continue Reading

  • Squire Patton Boggs Advises GBG on Acquisition of DataTools

    Squire Patton Boggs Advises GBG on Acquisition of DataTools

    Squire Patton Boggs has advised GBG, a global identity technology business, on the acquisition of DataTools Pty Limited, a leading provider of address validation and data quality solutions in Australia and New Zealand.

    The Squire Patton Boggs team was led by Corporate partners Louisa Hine (Sydney) and Giles Chesher (Manchester).

    DataTools is one of the largest providers of address validation and data quality solutions in Australia and New Zealand (ANZ). The acquisition adds scale and deepens GBG’s existing address verification presence in ANZ and is complementary to GBG’s identity verification platform, enhancing its broader proposition in the region.

    Continue Reading