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  • Onward Therapeutics Exercises Exclusive Option and Signs Worldwide License Agreement with Institut du Cancer de Montpellier for Novel Onco-Metabolism Program

    Onward Therapeutics Exercises Exclusive Option and Signs Worldwide License Agreement with Institut du Cancer de Montpellier for Novel Onco-Metabolism Program

    EPALINGES, Switzerland, Oct. 27, 2025 /PRNewswire/ — Onward Therapeutics SA, a clinical stage oncology company, today announced that its French subsidiary, Onward Therapeutics…

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  • ‘Impossible’ Life Found Beneath Arctic Ice Could Alter Climate Models : ScienceAlert

    ‘Impossible’ Life Found Beneath Arctic Ice Could Alter Climate Models : ScienceAlert

    Scientists have discovered special life forms thriving under Arctic sea ice. Until now, their presence in these dark and frigid conditions wasn’t thought possible, and the findings could have global implications for the climate.

    Nitrogen gas…

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  • Japan’s Nikkei 225 set to continue run above 50,000 as Trump meets Takaichi

    Japan’s Nikkei 225 set to continue run above 50,000 as Trump meets Takaichi

    U.S. President Donald Trump meets with Japan’s Emperor Naruhito at the Imperial Palace in Tokyo on Oct. 27, 2025.

    Kazuhiro Nogi | Afp | Getty Images

    Japan’s Nikkei 225 is set to continue its record-breaking climb above the 50,000 mark on Tuesday as U.S. President Donald Trump is set to meet with newly minted Japanese Prime Minister Sanae Takaichi.

    Futures signaled further gains for Tokyo stocks, with the Nikkei contract in Chicago at 50,700 and its Osaka counterpart at 50,520, compared with Monday’s close of 50,512.32.

    Trump met Japan’s Emperor Naruhito after arriving in Tokyo on Monday and will be the first foreign leader to hold talks with Takaichi since she took office.

    Other Asia-Pacific markets are set to open mixed on Tuesday, despite gains on Wall Street that saw all three major U.S. indexes reach record closing highs.

    Hong Kong Hang Seng index futures were at 26,534, higher than the HSI’s last close of 26,433.7.

    Australia’s S&P/ASX 200 started the day down 0.21%.

    Overnight in the U.S., the S&P 500 climbed 1.23% to 6,875.16, its first close ever above the 6,800 level.

    The Nasdaq Composite rallied 1.86% to 23,637.46, bolstered by a rise in Nvidia and other chip stocks. The Dow Jones Industrial Average jumped 337.47 points, or 0.71% to 47,544.59. 

    Key market catalysts loom ahead this week, including Big Tech earnings, a Federal Reserve rate decision and a potential China trade deal.

    — CNBC’s John Melloy, Sean Conlon and Liz Napolitano contributed to this report.

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  • Norrie eager for Alcaraz test: 'I'm going to take it to him' – ATP Tour

    1. Norrie eager for Alcaraz test: ‘I’m going to take it to him’  ATP Tour
    2. Carlos Alcaraz vs Cameron Norrie Prediction: Can Norrie’s Grit Challenge Alcaraz’s Indoor Firepower?  Telecom Asia Sport
    3. Paris Masters Round-Up: Andrey Rublev snaps losing…

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  • Patient-Derived Xenograft Mouse Model of a Rare Gynecologic Malignancy: Personalized Medicine for the Treatment of Mesonephric-Like Adenocarcinoma

    Patient-Derived Xenograft Mouse Model of a Rare Gynecologic Malignancy: Personalized Medicine for the Treatment of Mesonephric-Like Adenocarcinoma

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  • Obesity’s health risks shift with age and sex, new genetic study reveals

    Obesity’s health risks shift with age and sex, new genetic study reveals

    A massive UK Biobank analysis reveals that the health risks of obesity shift over time, peaking at different ages for men and women, and that midlife preventive care may blunt its cardiovascular damage.

    Study: Time-resolved…

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  • Just a moment…

    Just a moment…

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  • Pentagon Disputes ‘House Of Dynamite’ Missile Accuracy; Screenwriter Responds

    Pentagon Disputes ‘House Of Dynamite’ Missile Accuracy; Screenwriter Responds

    The Department of Defense and Netflix are in a clash over how accurate nuclear disaster drama A House of Dynamite truly is.

    Highlighting a specific major HoD plot point, an October 16 memo from officials at the Pentagon was produced with…

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  • Cross-Border LGBTQ+ Drama ‘Polaris’ Debuts at Tokyo Market

    Cross-Border LGBTQ+ Drama ‘Polaris’ Debuts at Tokyo Market

    A new Japanese-Taiwanese co-production is seeking financing at the Tokyo Gap-Financing Market, bringing together voices from across borders to tell an intimate story set in Tokyo’s LGBTQ+ hub.

    “Polaris,” directed by Seta Natsuki and…

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  • Australia’s largest aluminium smelter Tomago ‘not commercially viable’ and may close, says Rio Tinto | Business

    Australia’s largest aluminium smelter Tomago ‘not commercially viable’ and may close, says Rio Tinto | Business

    Rio Tinto says it is contemplating ceasing operations at its New South Wales-based Tomago aluminium smelter at the end of its current electricity supply contract.

    The Tomago aluminium smelter, Australia’s largest, had been struggling with high power prices. It had started a consultation process with employees on the potential future of its operations, but was yet to reach a decision and is weighing a possible closure.

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    The smelter’s existing electricity supply contract with AGL Energy expires in December 2028, with Tomago yet to identify a pathway that supports commercially sustainable operations beyond the period “despite extensive engagement and market approaches”, according to the miner’s statement.

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    “Unfortunately, all market proposals received so far show future energy prices are not commercially viable, and there is significant uncertainty about when renewable projects will be available at the scale we need,” Tomago Aluminium’s CEO, Jérôme Dozol, said.

    A number of smelters in Australia are preparing to switch to 100% renewable energy in the coming decade. Tomago Aluminium, located north-west of Newcastle, had announced in 2021 it would “for all intents and purposes” be 100% renewable by 2029.

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