Liz Reid, the Google search boss, has a tough job.
She’s going around trying to convince the public that artificial intelligence hasn’t killed Google’s golden goose—the search business that makes up more than half of parent-company
This request seems a bit unusual, so we need to confirm that you’re human. Please press and hold the button until it turns completely green. Thank you for your cooperation!
Scientists have created a new and more advanced form of immune-based cancer therapy using engineered cells known as CAR-NK (natural killer) cells. Like CAR-T cells, these modified immune cells can be programmed to recognize and attack cancer, but…
Kylian Mbappé has been released from the France squad and will return to Real Madrid for treatment on an ankle injury, the French Football Federation have confirmed.
Mbappé arrived at the France camp carrying a minor issue with his ankle, the…
Astronomers have captured a radio image showing two black holes orbiting each other for the first time, just six years after the release of the first-ever photo of a single black hole.
The…
Syeda Aliza Sultan is an influencer and ex-wife of actor Feroze Khan. They got married and their marriage remained very private until one day the divorce proceedings were happening. They have two kids together and the custody for children as well…
Armillotta M, Bergamaschi L, Paolisso P, Belmonte M, Angeli F, Sansonetti A, et al. Prognostic relevance of Type 4a myocardial infarction and periprocedural myocardial injury in patients with non-ST-segment-elevation myocardial infarction. Circulation. 2025;151(11):760–72.
Google Scholar
Lopaschuk GD, Stanley WC. Glucose metabolism in the ischemic heart. Circulation. 1997;95(2):313–5.
Google Scholar
Norhammar A, Tenerz A, Nilsson G, Hamsten A, Efendíc S, Rydén L, et al. Glucose metabolism in patients with acute myocardial infarction and no previous diagnosis of diabetes mellitus: a prospective study. Lancet. 2002;359(9324):2140–4.
Google Scholar
Paolisso P, Foa A, Bergamaschi L, Angeli F, Fabrizio M, Donati F, et al. Impact of admission hyperglycemia on short and long-term prognosis in acute myocardial infarction: MINOCA versus MIOCA. Cardiovasc Diabetol. 2021;20(1):192.
Google Scholar
Paolisso P, Foà A, Bergamaschi L, Donati F, Fabrizio M, Chiti C, et al. Hyperglycemia, inflammatory response and infarct size in obstructive acute myocardial infarction and MINOCA. Cardiovasc Diabetol. 2021;20(1):33.
Google Scholar
Marfella R, Sasso FC, Siniscalchi M, Paolisso P, Rizzo MR, Ferraro F, et al. Peri-procedural tight glycemic control during early percutaneous coronary intervention is associated with a lower rate of in-stent restenosis in patients with acute ST-elevation myocardial infarction. J Clin Endocrinol Metab. 2012;97(8):2862–71.
Google Scholar
Zhang JW, Zhou YJ, Cao SJ, Yang Q, Yang SW, Nie B. Impact of stress hyperglycemia on in-hospital stent thrombosis and prognosis in nondiabetic patients with ST-segment elevation myocardial infarction undergoing a primary percutaneous coronary intervention. Coron Artery Dis. 2013;24(5):352–6.
Google Scholar
Khalfallah M, Abdelmageed R, Elgendy E, Hafez YM. Incidence, predictors and outcomes of stress hyperglycemia in patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention. Diab Vasc Dis Res. 2020;17(1):1479164119883983.
Google Scholar
Stalikas N, Papazoglou AS, Karagiannidis E, Panteris E, Moysidis D, Daios S, et al. Association of stress induced hyperglycemia with angiographic findings and clinical outcomes in patients with ST-elevation myocardial infarction. Cardiovasc Diabetol. 2022;21(1):140.
Google Scholar
Algül E, Özbeyaz NB, Şahan HF, Aydınyılmaz F, Sunman H, Tulmaç M. Stress hyperglycemia ratio is associated with high thrombus burden in patients with acute coronary syndrome. Angiology. 2023;75(7):645–50.
Google Scholar
Roberts GW, Quinn SJ, Valentine N, Alhawassi T, O’Dea H, Stranks SN, et al. Relative hyperglycemia, a marker of critical illness: introducing the stress hyperglycemia ratio. J Clin Endocrinol Metab. 2015;100(12):4490–7.
Google Scholar
Sia CH, Chan MH, Zheng H, Ko J, Ho AF, Chong J, et al. Optimal glucose, HbA1c, glucose-HbA1c ratio and stress-hyperglycaemia ratio cut-off values for predicting 1-year mortality in diabetic and non-diabetic acute myocardial infarction patients. Cardiovasc Diabetol. 2021;20(1):211.
Google Scholar
Xu W, Yang YM, Zhu J, Wu S, Wang J, Zhang H, et al. Predictive value of the stress hyperglycemia ratio in patients with acute ST-segment elevation myocardial infarction: insights from a multi-center observational study. Cardiovasc Diabetol. 2022;21(1):48.
Google Scholar
Liao W, Chen Y, Gao Q, Gan R, Li M, Liu Z, et al. Impact of stress hyperglycemia ratio, derived from glycated albumin or hemoglobin A1c, on mortality among ST-segment elevation myocardial infarction patients. Cardiovasc Diabetol. 2023;22(1):334.
Google Scholar
Nusca A, Patti G, Marino F, Mangiacapra F, D’Ambrosio A, Di Sciascio G. Prognostic role of preprocedural glucose levels on short- and long-term outcome in patients undergoing percutaneous coronary revascularization. Catheter Cardiovasc Interv. 2012;80(3):377–84.
Google Scholar
Xia J, Xu J, Hu S, Hao H, Yin C, Xu D. Impact of glycemic variability on the occurrence of periprocedural myocardial infarction and major adverse cardiovascular events (MACE) after coronary intervention in patients with stable angina pectoris at 6months follow-up. Clin Chim Acta. 2017;471:196–200.
Google Scholar
Tandjung K, van Houwelingen KG, Jansen H, Basalus MW, Sen H, Lowik MM, et al. Comparison of frequency of periprocedural myocardial infarction in patients with and without diabetes mellitus to those with previously unknown but elevated glycated hemoglobin levels (from the TWENTE Trial). Am J Cardiol. 2012;110(11):1561–7.
Google Scholar
Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, et al. Fourth universal definition of myocardial infarction (2018). Eur Heart J. 2019;40(3):237–69.
Google Scholar
Byrne RA, Rossello X, Coughlan JJ, Barbato E, Berry C, Chieffo A, et al. 2023 ESC Guidelines for the management of acute coronary syndromes. Eur Heart J. 2023;44(38):3720–826.
Google Scholar
American Diabetes Association Professional Practice C. 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2022. Diabetes Care. 2022;45(Suppl 1):S17-S38.
Fujino M, Ishihara M, Honda S, Kawakami S, Yamane T, Nagai T, et al. Impact of acute and chronic hyperglycemia on in-hospital outcomes of patients with acute myocardial infarction. Am J Cardiol. 2014;114(12):1789–93.
Google Scholar
Marenzi G, Cosentino N, Milazzo V, De Metrio M, Cecere M, Mosca S, et al. Prognostic value of the acute-to-chronic glycemic ratio at admission in acute myocardial infarction: a prospective study. Diabetes Care. 2018;41(4):847–53.
Google Scholar
Marenzi G, Cosentino N, Milazzo V, De Metrio M, Rubino M, Campodonico J, et al. Acute kidney injury in diabetic patients with acute myocardial infarction: role of acute and chronic glycemia. J Am Heart Assoc. 2018;7(8):e008122.
Google Scholar
Lin Z, Liang X, Zhang Y, Dai Y, Zeng L, Chen W, et al. Positive association between stress hyperglycemia ratio and pulmonary infection in patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention. Cardiovasc Diabetol. 2023;22(1):76.
Google Scholar
Malmberg K, Ryden L, Efendic S, Herlitz J, Nicol P, Waldenstrom A, et al. Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 year. J Am Coll Cardiol. 1995;26(1):57–65.
Google Scholar
Malmberg K, Ryden L, Wedel H, Birkeland K, Bootsma A, Dickstein K, et al. Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity. Eur Heart J. 2005;26(7):650–61.
Google Scholar
Deedwania P, Kosiborod M, Barrett E, Ceriello A, Isley W, Mazzone T, et al. Hyperglycemia and acute coronary syndrome: a scientific statement from the American Heart Association Diabetes Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation. 2008;117(12):1610–9.
Google Scholar
Li L, Zhao M, Zhang Z, Zhou L, Zhang Z, Xiong Y, et al. Prognostic significance of the stress hyperglycemia ratio in critically ill patients. Cardiovasc Diabetol. 2023;22(1):275.
Google Scholar
Mone P, Lombardi A, Salemme L, Cioppa A, Popusoi G, Varzideh F, et al. Stress hyperglycemia drives the risk of hospitalization for chest pain in patients with ischemia and nonobstructive coronary arteries (INOCA). Diabetes Care. 2023;46(2):450–4.
Google Scholar
Angeli F, Reboldi G, Poltronieri C, Lazzari L, Sordi M, Garofoli M, et al. Hyperglycemia in acute coronary syndromes: from mechanisms to prognostic implications. Ther Adv Cardiovasc Dis. 2015;9(6):412–24.
Google Scholar
Gustavsson C, Agardh CD, Zetterqvist AV, Nilsson J, Agardh E, Gomez MF. Vascular cellular adhesion molecule-1 (VCAM-1) expression in mice retinal vessels is affected by both hyperglycemia and hyperlipidemia. PLoS ONE. 2010;5(9): e12699.
Google Scholar
Piconi L, Quagliaro L, Da Ros R, Assaloni R, Giugliano D, Esposito K, et al. Intermittent high glucose enhances ICAM-1, VCAM-1, E-selectin and interleukin-6 expression in human umbilical endothelial cells in culture: the role of poly(ADP-ribose) polymerase. J Thromb Haemost. 2004;2(8):1453–9.
Google Scholar
Undas A, Wiek I, Stepien E, Zmudka K, Tracz W. Hyperglycemia is associated with enhanced thrombin formation, platelet activation, and fibrin clot resistance to lysis in patients with acute coronary syndrome. Diabetes Care. 2008;31(8):1590–5.
Google Scholar
Abassi Z, Armaly Z, Heyman SN. Glycocalyx degradation in ischemia-reperfusion injury. Am J Pathol. 2020;190(4):752–67.
Google Scholar
Maksimenko AV, Turashev AD. No-reflow phenomenon and endothelial glycocalyx of microcirculation. Biochem Res Int. 2012;2012: 859231.
Google Scholar
Oswald GA, Smith CC, Betteridge DJ, Yudkin JS. Determinants and importance of stress hyperglycaemia in non-diabetic patients with myocardial infarction. Br Med J (Clin Res Ed). 1986;293(6552):917–22.
Google Scholar
Li M, Chi X, Wang Y, Setrerrahmane S, Xie W, Xu H. Trends in insulin resistance: insights into mechanisms and therapeutic strategy. Signal Transduct Target Ther. 2022;7(1):216.
Google Scholar
Yang J, Zheng Y, Li C, Gao J, Meng X, Zhang K, et al. The Impact of the stress hyperglycemia ratio on short-term and long-term poor prognosis in patients with acute coronary syndrome: insight from a large cohort study in Asia. Diabetes Care. 2022;45(4):947–56.
Google Scholar
Zeng G, Song Y, Zhang Z, Xu J, Liu Z, Tang X, et al. Stress hyperglycemia ratio and long-term prognosis in patients with acute coronary syndrome: A multicenter, nationwide study. J Diabetes. 2023;15(7):557–68.
Google Scholar
Schmitz T, Freuer D, Harmel E, Heier M, Peters A, Linseisen J, et al. Prognostic value of stress hyperglycemia ratio on short- and long-term mortality after acute myocardial infarction. Acta Diabetol. 2022;59(8):1019–29.
Google Scholar
Gio Lo Celso grabbed the only goal as Argentina eased to a 1-0 win over Venezuela in a rather drab international friendly held at Miami’s Hard Rock Stadium. The reigning World Cup champions were a little languid as the game wore on in the absence…
I don’t know when it started, because it definitely wasn’t always like this, but Grindr has a serious problem. You can’t do a single damn thing on the app without being smacked in the face…
