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  • Cruise from Puerto Rico w/ Nicky Jam | Latin Music Cruise

    Cruise from Puerto Rico w/ Nicky Jam | Latin Music Cruise

    Forget muddy fields and overpriced water bottles. Olas de Fuego: Nicky Jam x Virgin Voyages is here to bring some much-needed style and comfort to a traditional music festival experience. 

    From December 5-13, we’re turning the Caribbean…

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  • Pakistan’s Hassan Ali wins Asian Youth Games wrestling bronze

    Pakistan’s Hassan Ali wins Asian Youth Games wrestling bronze

    Pakistani wrestler Hassan Ali on the Asian Youth Games podium with his bronze medal. PHOTO: Pakistan Olympic Association

    Pakistan’s Hassan Ali grabbed…

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  • Meta to raise $25bn from bond sale amid soaring AI costs

    Meta to raise $25bn from bond sale amid soaring AI costs

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    Meta is planning to raise $25bn from a bond sale to help it pay for soaring artificial intelligence costs, even as the Big Tech group’s share price fell amid concerns that its spending is too high.

    The social media group has hired Citigroup and Morgan Stanley to raise up to $25bn in debt, ranging from five to 40 years in maturity, in what would be one of the biggest bond sales of the year, according to two people close to the matter.

    It comes a day after chief executive Mark Zuckerberg warned that the US tech group would spend even more aggressively as part of an arms race to build the data centres and infrastructure powering the AI boom.

    Meta’s shares fell 12 per cent after Wall Street’s opening bell on Thursday — wiping out about almost $240bn from its valuation — as investors fretted over the tech group’s huge outlay.

    The sale underscores how technology giants are increasingly turning to the debt markets as they spend record sums to build AI infrastructure.

    Meta raised $27bn of private debt from credit providers, including Pimco and Apollo, in recent months to fund construction of its huge “Hyperion” data centre in Louisiana. Oracle sold $18bn of bonds in September.

    Large tech companies are projected to invest $400bn on AI infrastructure this year, including buying computer chips and building data centres. On Wednesday, Meta, Microsoft and Google’s parent Alphabet all disclosed larger than expected spending plans in the current quarter.

    The social media company said capex could hit $72bn by the end of the year and that spending growth would be “notably larger” in 2026, implying a number far in excess of an earlier forecast for $105bn.

    Zuckerberg defended huge spending on infrastructure for Meta’s own use. He told analysts on Wednesday that it was “the right strategy to aggressively frontload building capacity” as part of the tech group’s bid to be the first to build artificial superintelligence. 

    At a recent dinner with US President Donald Trump, Zuckerberg said the company planned to spend $600bn on US data centres and AI infrastructure through 2028.

    Meta, Citigroup and Morgan Stanley declined to comment. The bond sale was first reported by Bloomberg.

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  • Advances in diagnosis and management of systemic light chain amyloidosis

    Advances in diagnosis and management of systemic light chain amyloidosis

    Systemic light chain (AL) amyloidosis is a rare and life-threatening disorder characterized by the deposition of misfolded immunoglobulin light chains as insoluble amyloid fibrils in various tissues and organs, leading to…

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  • U.S.-China Truce Brings Little Peace for Businesses Caught in Superpower Standoff – The Wall Street Journal

    1. U.S.-China Truce Brings Little Peace for Businesses Caught in Superpower Standoff  The Wall Street Journal
    2. Xi and Trump find temporary truce as China plays longer game  BBC
    3. Trump and Xi reach trade deal, easing tensions in fierce US-China rivalry  

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  • New Mechanism Enables Precision Biased GPCR Therapies

    New Mechanism Enables Precision Biased GPCR Therapies

    About one-third of all drugs approved by the Food and Drug Administration target the largest family of cell membrane receptors called G protein-coupled receptors (GPCRs).

    GPCRs are indispensable for maintaining human health as they play a…

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  • Just a moment…

    Just a moment…

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  • New chemotherapeutic agent shows remarkable efficacy against multiple tumor types

    New chemotherapeutic agent shows remarkable efficacy against multiple tumor types

    A research team led by the Medical University of Vienna, the HUN-REN Research Centre for Natural Sciences and the Eötvös Loránd University in Budapest has developed a groundbreaking new chemotherapeutic agent, LiPyDau, which…

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  • Seth Meyers on Trump’s South Korea visit: ‘Getting the royal treatment he so desperately craves’ | Late-night TV roundup

    Seth Meyers on Trump’s South Korea visit: ‘Getting the royal treatment he so desperately craves’ | Late-night TV roundup

    Late-night hosts recapped Donald Trump’s lavish visit to South Korea, where he received a ceremonial golden crown.

    Seth Meyers

    Trump continued his tour of Asia on Wednesday, where he’s been “getting the royal treatment he so desperately…

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