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  • EWEC signs PPA with Engie and Masdar for 1.5 GW Khazna solar project (UAE) – Enerdata

    1. EWEC signs PPA with Engie and Masdar for 1.5 GW Khazna solar project (UAE)  Enerdata
    2. Abu Dhabi awards contract for a mega solar project  The Times of India
    3. Masdar Unveils World’s First Gigascale 24/7 Solar and Battery Storage Project to Deliver Continuous Clean Power  SolarQuarter
    4. Engie, Masdar win 1.5 GW solar project in UAE  pv magazine International
    5. French Engie and Emirati Masdar win contract for Abu Dhabi for mega solar project  The Arab Weekly

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  • Galaxy Watch 7 gets Wear OS 6 with stable One UI 8 Watch update

    Galaxy Watch 7 gets Wear OS 6 with stable One UI 8 Watch update

    Samsung was the first to bring Wear OS 6–powered smartwatches to market with the Galaxy Watch 8 and Watch Ultra (2025). Around the same time those models hit retail shelves, the company rolled out the stable One UI 8 Watch build for the Galaxy…

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  • Figure skating – Ilia Malinin to challenge three-time winner Adam Siao Him Fa for title at ISU Grand Prix de France 2025: Preview, schedule, how to watch live

    Figure skating – Ilia Malinin to challenge three-time winner Adam Siao Him Fa for title at ISU Grand Prix de France 2025: Preview, schedule, how to watch live

    Six-time Grand Prix de France winner Guillaume Cizeron will return to the familiar stage for the first time since 2021, this time with new partner Laurence Fournier-Beaudry. The Beijing 2022 Olympians created a buzz when they announced in March…

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    You don’t have permission to access “http://www.ndtv.com/world-news/israel-gaza-ceasefire-live-updates-israel-launches-operation-returning-home-to-free-hostages-held-by-hamas-9443620” on this server.

    Reference…

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  • Map Reveals How DNA Mutations Drive Resistance

    Map Reveals How DNA Mutations Drive Resistance

    Every organism’s genome contains mutations that often have unknown biological effects. In partnership with Stanford University (USA), researchers at Charité – Universitätsmedizin Berlin have now discovered a way to predict the…

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  • Can a Sweetener Really Regrow Hair? New Research Says Yes – SciTechDaily

    1. Can a Sweetener Really Regrow Hair? New Research Says Yes  SciTechDaily
    2. A sweet fix for baldness? Stevia compound boosts hair growth  ScienceDaily
    3. Natural sweetener found to turbocharge baldness treatment  New Atlas
    4. Stevia for hair loss? Study finds…

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  • Microdrama Boom Goes Global at Mipcom

    Microdrama Boom Goes Global at Mipcom

    AR is presenting an extensive selection of microdramas from China and beyond at the ongoing Mipcom market.

    The company operates across the $7 billion Chinese and $4 billion international short-form content sectors, with a library of 1,000…

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  • Canberra welcomes four global conferences

    Canberra welcomes four global conferences

    Mount Stromlo; photo by Visit Canberra

    Canberra has successfully secured four international conferences spanning space science, artificial intelligence, human-computer interaction, and healthcare, this spring.

    The influx of…

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  • Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74:229–63.

    PubMed 

    Google Scholar 

  • Burstein HJ, Curigliano G, Thürlimann B, Weber WP, Poortmans P, Regan MM et al. Customizing local and systemic therapies for women with early breast cancer: the St. Gallen International Consensus Guidelines for treatment of early breast cancer 2021. Ann Oncol 2021; 32: 1216–1235.

  • Loibl S, André F, Bachelot T, Barrios CH, Bergh J, Burstein HJ, et al. Early breast cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Ann Oncol. 2024;35:159–82.

    CAS 
    PubMed 

    Google Scholar 

  • Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, et al. Molecular portraits of human breast tumours. Nature. 2000;406:747–52.

    CAS 
    PubMed 

    Google Scholar 

  • Sørlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A. 2001;98:10869–74.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Network CGA. Comprehensive molecular portraits of human breast tumours. Nature. 2012;490:61–70.

    Google Scholar 

  • Prat A, Pineda E, Adamo B, Galván P, Fernández A, Gaba L, et al. Clinical implications of the intrinsic molecular subtypes of breast cancer. Breast. 2015;24(Suppl 2):S26-35.

    PubMed 

    Google Scholar 

  • Paik S, Tang G, Shak S, Kim C, Baker J, Kim W, et al. Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer. J Clin Oncol. 2006;24:3726–34.

    CAS 
    PubMed 

    Google Scholar 

  • Sparano JA, Gray RJ, Makower DF, Pritchard KI, Albain KS, Hayes DF, et al. Adjuvant chemotherapy guided by a 21-gene expression assay in breast cancer. N Engl J Med. 2018;379:111–21.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Confederation of Regional Cancer Centres in Sweden. National Clinical Cancer Care Guidelines Breast Cancer. 2024. https://kunskapsbanken.cancercentrum.se/globalassets/cancerdiagnoser/brost/vardprogram/nationellt-vardprogram-brostcancer.pdf (Accessed 24 Oct 2024).

  • Waks AG, Winer EP. Breast Cancer Treatment: A Review. JAMA. 2019;321:288–300.

    CAS 
    PubMed 

    Google Scholar 

  • Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials. Lancet 2015; 386: 1341–1352.

  • Herzog SK, Fuqua SAW. ESR1 mutations and therapeutic resistance in metastatic breast cancer: progress and remaining challenges. Br J Cancer. 2022;126:174–86.

    CAS 
    PubMed 

    Google Scholar 

  • Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Aromatase inhibitors versus tamoxifen in premenopausal women with oestrogen receptor-positive early-stage breast cancer treated with ovarian suppression: a patient-level meta-analysis of 7030 women from four randomised trials. Lancet Oncol 2022; 23: 382–392.

  • Turner NC, Oliveira M, Howell SJ, Dalenc F, Cortes J, Gomez Moreno HL, et al. Capivasertib in Hormone Receptor-Positive Advanced Breast Cancer. N Engl J Med. 2023;388:2058–70.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Bidard F-C, Kaklamani VG, Neven P, Streich G, Montero AJ, Forget F, et al. Elacestrant (oral selective estrogen receptor degrader) versus standard endocrine therapy for estrogen receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: Results from the randomized phase III EMERALD trial. J Clin Oncol. 2022;40:3246–56.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Makhlin I, Fallowfield L, Henry NL, Burstein HJ, Somerfield MR, DeMichele A. Targeted therapies, sequencing strategies, and beyond in metastatic hormone receptor-positive breast cancer: ASCO guideline clinical insights. JCO Oncol Pract 2024; : OP2400547.

  • AlFakeeh A, Brezden-Masley C. Overcoming endocrine resistance in hormone receptor-positive breast cancer. Curr Oncol. 2018;25:S18–27.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Early Breast Cancer Trialists’ Collaborative Group (EBCTCG), Davies C, Godwin J, Gray R, Clarke M, Cutter D et al. Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials. Lancet 2011; 378: 771–784.

  • Pan H, Gray R, Braybrooke J, Davies C, Taylor C, McGale P, et al. 20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years. N Engl J Med. 2017;377:1836–46.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005; 365: 1687–1717.

  • Miranda F, Prazeres H, Mendes F, Martins D, Schmitt F. Resistance to endocrine therapy in HR + and/or HER2 + breast cancer: the most promising predictive biomarkers. Mol Biol Rep. 2022;49:717–33.

    CAS 
    PubMed 

    Google Scholar 

  • Clarke R, Tyson JJ, Dixon JM. Endocrine resistance in breast cancer–An overview and update. Mol Cell Endocrinol. 2015;418(Pt 3):220–34.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Rasha F, Sharma M, Pruitt K. Mechanisms of endocrine therapy resistance in breast cancer. Mol Cell Endocrinol. 2021;532: 111322.

    CAS 
    PubMed 

    Google Scholar 

  • Dustin D, Gu G, Fuqua SAW. ESR1 mutations in breast cancer. Cancer. 2019;125:3714–28.

    PubMed 

    Google Scholar 

  • Saatci O, Huynh-Dam K-T, Sahin O. Endocrine resistance in breast cancer: from molecular mechanisms to therapeutic strategies. J Mol Med. 2021;99:1691–710.

    CAS 
    PubMed 

    Google Scholar 

  • Haque MM, Desai KV. Pathways to Endocrine Therapy Resistance in Breast Cancer. Front Endocrinol. 2019;10:573.

    Google Scholar 

  • Hanker AB, Sudhan DR, Arteaga CL. Overcoming Endocrine Resistance in Breast Cancer. Cancer Cell. 2020;37:496–513.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Sauerbrei W, Taube SE, McShane LM, Cavenagh MM, Altman DG. Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): An abridged explanation and elaboration. J Natl Cancer Inst. 2018;110:803–11.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Moore HM, Kelly AB, Jewell SD, McShane LM, Clark DP, Greenspan R, et al. Biospecimen reporting for improved study quality (BRISQ). Cancer Cytopathol. 2011;119:92–101.

    PubMed 

    Google Scholar 

  • Tarantino P, Viale G, Press MF, Hu X, Penault-Llorca F, Bardia A, et al. ESMO expert consensus statements (ECS) on the definition, diagnosis, and management of HER2-low breast cancer. Ann Oncol. 2023;34:645–59.

    CAS 
    PubMed 

    Google Scholar 

  • Denkert C, Loibl S, Noske A, Roller M, Müller BM, Komor M, et al. Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer. J Clin Oncol. 2010;28:105–13.

    CAS 
    PubMed 

    Google Scholar 

  • Salgado R, Denkert C, Demaria S, Sirtaine N, Klauschen F, Pruneri G, et al. The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014. Ann Oncol. 2015;26:259–71.

    CAS 
    PubMed 

    Google Scholar 

  • BEA core facility. Bioinformatics and Expression Analysis. http://www.bea.ki.se/ (accessed 5 Mar2023).

  • Thermo Fisher Scientific Inc. Transcriptome Analysis Console (TAC) v4.0.3 User Guide. Affymetrix Inc., 2022https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/TAC_v4.0.3_User_Guide.pdf (accessed 24 Oct2024).

  • Mootha VK, Lindgren CM, Eriksson K-F, Subramanian A, Sihag S, Lehar J, et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet. 2003;34:267–73.

    CAS 
    PubMed 

    Google Scholar 

  • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005;102:15545–50.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Liberzon A, Subramanian A, Pinchback R, Thorvaldsdóttir H, Tamayo P, Mesirov JP. Molecular signatures database (MSigDB) 3.0. Bioinformatics 2011; 27: 1739–1740.

  • Liberzon A, Birger C, Thorvaldsdóttir H, Ghandi M, Mesirov JP, Tamayo P. The Molecular Signatures Database (MSigDB) hallmark gene set collection. Cell Syst. 2015;1:417–25.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kanehisa M, Goto S. KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res. 2000;28(1):27. https://doi.org/10.1093/nar/28.1.27.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. The reactome pathway knowledgebase 2024. Nucleic Acids Res. 2024;52(D1):D672–8. https://doi.org/10.1093/nar/gkad1025.

  • The Broad Institute. GSEA User Guide. GSEA. 2004–2024. http://www.gsea-msigdb.org/gsea/doc/GSEAUserGuideFrame.html?_Interpreting_GSEA_Results (Accessed 24 Oct 2024).

  • Curtis C, Shah SP, Chin S-F, Turashvili G, Rueda OM, Dunning MJ, et al. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature. 2012;486:346–52.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Rueda OM, Sammut S-J, Seoane JA, Chin S-F, Caswell-Jin JL, Callari M, et al. Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups. Nature. 2019;567:399–404.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Hänzelmann S, Castelo R, Guinney J. GSVA: gene set variation analysis for microarray and RNA-seq data. BMC Bioinformatics. 2013;14:7.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Bhuva D, Smyth G, Garnham A. msigdb: An ExperimentHub Package for the Molecular Signatures Database (MSigDB). R package version 1.14.0. 2024. https://davislaboratory.github.io/msigdb.

  • Zhao X, Rødland EA, Tibshirani R, Plevritis S. Molecular subtyping for clinically defined breast cancer subgroups. Breast Cancer Res. 2015;17:29.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Parker JS, Mullins M, Cheang MCU, Leung S, Voduc D, Vickery T, et al. Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol. 2009;27:1160–7.

    PubMed 
    PubMed Central 

    Google Scholar 

  • R Foundation for Statistical Computing, Vienna, Austria. R: A language and environment for statistical computing. https://www.R-project.org/.

  • Prat A, Lluch A, Turnbull AK, Dunbier AK, Calvo L, Albanell J, et al. A PAM50-based chemoendocrine score for hormone receptor-positive breast cancer with an intermediate risk of relapse. Clin Cancer Res. 2017;23:3035–44.

    CAS 
    PubMed 

    Google Scholar 

  • Pascual T, Fernandez-Martinez A, Tanioka M, Dieci MV, Pernas S, Gavila J, et al. Independent validation of the PAM50-based chemo-endocrine score (CES) in hormone receptor–positive HER2-positive breast cancer treated with neoadjuvant anti–HER2-based therapy. Clin Cancer Res. 2021;27:3116–25.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Microsoft Corporation. Microsoft® Excel® for Microsoft 365 MSO. Available from: https://office.microsoft.com/excel.

  • Tolaney SM, Garrett-Mayer E, White J, Blinder VS, Foster JC, Amiri-Kordestani L et al. Updated Standardized Definitions for Efficacy End Points (STEEP) in adjuvant breast cancer clinical trials: STEEP version 2.0. J Clin Oncol 2021; 39: 2720–2731.

  • Curigliano G, Burstein HJ, Winer EP, Gnant M, Dubsky P, Loibl S et al. De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017. Ann Oncol 2017; 28: 1700–1712.

  • Goldhirsch A, Wood WC, Coates AS, Gelber RD, Thürlimann B, Senn H-J et al. Strategies for subtypes–dealing with the diversity of breast cancer: highlights of the St. Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011. Ann Oncol 2011; 22: 1736–1747.

  • Yu NY, Iftimi A, Yau C, Tobin NP, van ’t Veer L, Hoadley KA et al. Assessment of long-term distant recurrence-free survival associated with tamoxifen therapy in postmenopausal patients with luminal A or luminal B breast cancer. JAMA Oncol 2019; 5: 1304–1309.

  • Ignatov A, Eggemann H, Burger E, Ignatov T. Patterns of breast cancer relapse in accordance to biological subtype. J Cancer Res Clin Oncol. 2018;144:1347–55.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Filipits M, Nielsen TO, Rudas M, Greil R, Stöger H, Jakesz R, et al. The PAM50 risk-of-recurrence score predicts risk for late distant recurrence after endocrine therapy in postmenopausal women with endocrine-responsive early breast cancer. Clin Cancer Res. 2014;20:1298–305.

    CAS 
    PubMed 

    Google Scholar 

  • Clusan L, Ferrière F, Flouriot G, Pakdel F. A Basic Review on Estrogen Receptor Signaling Pathways in Breast Cancer. Int J Mol Sci 2023; 24. https://doi.org/10.3390/ijms24076834.

  • Heldring N, Pike A, Andersson S, Matthews J, Cheng G, Hartman J, et al. Estrogen receptors: how do they signal and what are their targets. Physiol Rev. 2007;87:905–31.

    CAS 
    PubMed 

    Google Scholar 

  • Fuentes N, Silveyra P. Estrogen receptor signaling mechanisms. Adv Protein Chem Struct Biol. 2019;116:135–70.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Nardone A, De Angelis C, Trivedi MV, Osborne CK, Schiff R. The changing role of ER in endocrine resistance. Breast. 2015;24(Suppl 2):S60–6.

    PubMed 

    Google Scholar 

  • Ghayad SE, Vendrell JA, Ben Larbi S, Dumontet C, Bieche I, Cohen PA. Endocrine resistance associated with activated ErbB system in breast cancer cells is reversed by inhibiting MAPK or PI3K/Akt signaling pathways. Int J Cancer. 2010;126:545–62.

    CAS 
    PubMed 

    Google Scholar 

  • André F, Ciruelos E, Rubovszky G, Campone M, Loibl S, Rugo HS, et al. Alpelisib for PIK3CA-Mutated, Hormone Receptor-Positive Advanced Breast Cancer. N Engl J Med. 2019;380:1929–40.

    PubMed 

    Google Scholar 

  • Finn RS, Crown JP, Lang I, Boer K, Bondarenko IM, Kulyk SO, et al. The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study. Lancet Oncol. 2015;16:25–35.

    CAS 
    PubMed 

    Google Scholar 

  • Kornblum N, Zhao F, Manola J, Klein P, Ramaswamy B, Brufsky A, et al. Randomized Phase II Trial of Fulvestrant Plus Everolimus or Placebo in Postmenopausal Women With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer Resistant to Aromatase Inhibitor Therapy: Results of PrE0102. J Clin Oncol. 2018;36:1556–63.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646–74.

    CAS 
    PubMed 

    Google Scholar 

  • Wang X, Sun Z, Zimmermann MT, Bugrim A, Kocher J-P. Predict drug sensitivity of cancer cells with pathway activity inference. BMC Med Genomics. 2019;12:15.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Belachew EB, Sewasew DT. Molecular Mechanisms of Endocrine Resistance in Estrogen-Positive Breast Cancer. Front Endocrinol. 2021;12: 599586.

    Google Scholar 

  • Harvell DME, Spoelstra NS, Singh M, McManaman JL, Finlayson C, Phang T, et al. Molecular signatures of neoadjuvant endocrine therapy for breast cancer: characteristics of response or intrinsic resistance. Breast Cancer Res Treat. 2008;112:475–88.

    CAS 
    PubMed 

    Google Scholar 

  • Liang X, Briaux A, Becette V, Benoist C, Boulai A, Chemlali W, et al. Molecular profiling of hormone receptor-positive, HER2-negative breast cancers from patients treated with neoadjuvant endocrine therapy in the CARMINA 02 trial (UCBG-0609). J Hematol Oncol. 2018;11:124.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Oshi M, Takahashi H, Tokumaru Y, Yan L, Rashid OM, Matsuyama R et al. G2M Cell Cycle Pathway Score as a Prognostic Biomarker of Metastasis in Estrogen Receptor (ER)-Positive Breast Cancer. Int J Mol Sci 2020; 21. https://doi.org/10.3390/ijms21082921.

  • Oshi M, Takahashi H, Tokumaru Y, Yan L, Rashid OM, Nagahashi M et al. The E2F Pathway Score as a Predictive Biomarker of Response to Neoadjuvant Therapy in ER+/HER2- Breast Cancer. Cells 2020; 9. https://doi.org/10.3390/cells9071643.

  • Shen W-J, Zhang Y. RPN1 promotes the proliferation and invasion of breast cancer cells by activating the PI3K/AKT/mTOR signaling pathway. Discov Oncol. 2024;15:25.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Althobiti M, El-Sharawy KA, Joseph C, Aleskandarany M, Toss MS, Green AR, et al. Oestrogen-regulated protein SLC39A6: a biomarker of good prognosis in luminal breast cancer. Breast Cancer Res Treat. 2021;189:621–30.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Oshi M, Tokumaru Y, Angarita FA, Yan L, Matsuyama R, Endo I et al. Degree of Early Estrogen Response Predict Survival after Endocrine Therapy in Primary and Metastatic ER-Positive Breast Cancer. Cancers 2020; 12. https://doi.org/10.3390/cancers12123557.

  • Takeshita T, Tokumaru Y, Oshi M, Wu R, Patel A, Tian W, et al. Clinical Relevance of Estrogen Reactivity in the Breast Cancer Microenvironment. Front Oncol. 2022;12: 865024.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Elfaki I, Mir R, Almutairi FM, Duhier FMA. Cytochrome P450: Polymorphisms and Roles in Cancer, Diabetes and Atherosclerosis. Asian Pac J Cancer Prev. 2018;19:2057–70.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Schroth W, Mürdter TE, Schwab M. Unraveling the impact of drug metabolism on tamoxifen response in breast cancer. Cancer Epidemiol Biomarkers Prev. 2025;34(2):221–3.

    CAS 
    PubMed 

    Google Scholar 

  • Bergers G, Fendt SM. The metabolism of cancer cells during metastasis. Nat Rev Cancer. 2021;21(3):162–80.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Reimand J, Isserlin R, Voisin V, Kucera M, Tannus-Lopes C, Rostamianfar A, et al. Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA. Cytoscape and EnrichmentMap Nat Protoc. 2019;14(2):482–517.

    CAS 
    PubMed 

    Google Scholar 

  • Bull C, Byrne RM, Fisher NC, Corry SM, Amirkhah R, Edwards J, et al. Dual gene set enrichment analysis (dualGSEA); an R function that enables more robust biological discovery and pre-clinical model alignment from transcriptomics data. Sci Rep 2024 4;14(1):30202.

  • El-Botty R, Morriset L, Montaudon E, Tariq Z, Schnitzler A, Bacci M, et al. Oxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers. Nat Commun. 2023;14(1):4221.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Wimmer I, Tröscher AR, Brunner F, Rubino SJ, Bien CG, Weiner HL, et al. Systematic evaluation of RNA quality, microarray data reliability and pathway analysis in fresh, fresh frozen and formalin-fixed paraffin-embedded tissue samples. Sci Rep. 2018;8:6351.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Sachs N, de Ligt J, Kopper O, Gogola E, Bounova G, Weeber F, et al. A living biobank of breast cancer organoids captures disease heterogeneity. Cell. 2018;172(1–2):373-386.e10.

    CAS 
    PubMed 

    Google Scholar 

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  • Phase shift in optical cavities could detect low-frequency gravitational waves – Physics World

    Phase shift in optical cavities could detect low-frequency gravitational waves – Physics World






    Phase shift in optical cavities could detect low-frequency gravitational waves – Physics World