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  • B&M told to remove ‘garish’ signs in Bedford town centre

    B&M told to remove ‘garish’ signs in Bedford town centre

    John GuinnLocal Democracy Reporting Service and

    Louise Parry

    Google The outside of B&M in Bedford, with two women chatting outside the store. Above the store front is a big bright B&M sign in blue and orange and a vinyl wrap saying "big brands big savings" in a large window.Google

    B&M has been told to remove signage from its store in Bedford town centre

    Retailer B&M has been told to take down “garish, obtrusive” signs that were put up without permission in a town conservation area.

    It appealed against an enforcement notice by Bedford Borough Council after complaints about its town centre store, but a planning inspector upheld the decision.

    The retailer must now remove the existing signage, which was put up in November 2023 at the shop on Midland Road.

    B&M said: “We are working closely with the council to agree a new replacement scheme.”

    Google The outside of B&M in Bedford, with a man walking past the store. Above the store front is a big bright B&M sign in blue and orange, and there are products stacked in the window.Google

    B&M has been told by government planners it must take its existing signage down

    Enforcement notices are issued when development or signage breaches planning control.

    The council previously asked the retailer to remove its vinyl signs and box tray fascia signs, but B&M appealed.

    Councillors were told at a planning committee on Monday that the government’s planning inspector had dismissed the bid.

    A report said the inspector found the vinyls had “a bleak and visually uninteresting appearance” and the fascias were “garish, prominent and obtrusive”.

    It said the signs did not preserve or enhance the character and appearance of the Bedford Conservation Area, according to the Local Democracy Reporting Service.

    Google The outside of the former M&S, showing its scaled back logo above the door. It is market day, and outside the front of the store is a big fruit and veg stall.Google

    The store was previously occupied by Marks & Spencer, which used a scaled back version of its typical sign

    While the inspector recognised there were benefits associated with the retail use of the building, he concluded they did not outweigh the great weight to be afforded to the conservation of heritage assets.

    Councillors praised the enforcement team’s work, highlighting the role it played in tackling unauthorised development and improving the borough’s appearance.

    “We’d be lost without them,” said Lib Dem councillor, Leigh Coombs.

    A spokesperson for B&M said: “B&M is proud to be one of Bedford’s major employers, with over 1,450 colleagues working in the area.

    “Our Midland Road store remains open for customers.

    “While we disagree with the comments made by the planning inspector, we are working closely with the council to agree a new replacement scheme.”

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  • Genetic screening reveals baby’s ‘out of the blue’ cancer

    Genetic screening reveals baby’s ‘out of the blue’ cancer

    A baby is expected to have his eyesight saved after a new screening tool picked up a rare eye cancer which may have otherwise gone undiagnosed.

    Just four weeks after he was born at Sheffield Teaching Hospital in April, Freddie was diagnosed with…

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  • Chimeric Therapeutics partners with Viral Vector Manufacturing Facility to boost GMP viral vector production

    Chimeric Therapeutics partners with Viral Vector Manufacturing Facility to boost GMP viral vector production

    Posted: 17 October 2025

    Chimeric Therapeutics (ASX:CHM) has signed a Letter of Intent (LOI) with Viral Vector Manufacturing Facility Pty Ltd (VVMF) to establish a strategic partnership focused on the development and Good Manufacturing Practice (GMP) production of Lentiviral vectors in Australia.

    Under the agreement, VVMF will support process development, technology transfer and GMP-grade manufacturing of Lentiviral vectors for Chimeric’s clinical-stage chimeric antigen receptor T-cell (CAR-T) therapy programme. Viral vectors are essential in producing CAR-T therapies, which are revolutionising cancer treatment worldwide.

    “We’re pleased to partner with VVMF as we continue to advance our CAR-T cell therapy programmes,” said Chimeric Therapeutics CEO Dr Rebecca McQualter. “Having access to local, GMP-grade viral vector manufacturing not only strengthens our supply chain but also supports the broader goal of building world-class advanced therapy capabilities here in Australia.”

    VVMF CEO Stephen Thompson said the collaboration would strengthen sovereign manufacturing and create high-value jobs in Western Sydney. “This collaboration allows us to demonstrate our capability to develop and manufacture GMP-grade viral vectors for the global cell and gene therapy marketplace,” he said.

    The agreement was described as a milestone for Australia’s growing advanced manufacturing sector and the development of Advanced Therapy Medicinal Products (ATMPs) — innovative medicines derived from genes, cells, or engineered tissues. These therapies are opening new possibilities for treating cancer, neurodegenerative, and cardiovascular diseases.

    Supported by strong R&D incentives, a pragmatic regulatory environment and a mature clinical trial ecosystem, Australia is well positioned to become a global hub for advanced therapy development and manufacturing.

    Find out more here.

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  • Great Barr family want change from maternity review after baby’s death

    Great Barr family want change from maternity review after baby’s death

    Joanne WrittleWest Midlands health correspondent

    BBC A woman with long blonde hair, wearing a blue top sits next to a man with dark hair and a dark beard, wearing a darker blue top, on a sofa in front of windows with closed Venetian blinds.BBC

    Lisa Blackstock and her son-in-law Samoye Richards said they were heartbroken and angry after Reggie’s death

    A family has described their heartbreak and anger after a mother was twice sent home…

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  • No reply to crash relatives over remains error

    No reply to crash relatives over remains error

    Chrissie Reidy and

    Craig BuchanSouth East

    Chrissie Reidy/BBC A man, Miten Patel, in a dark jumper, looking into the camera. In the background is a large image of two people in formal attire and a bouquet of white flowers. Chrissie Reidy/BBC

    Miten Patel wrote to the foreign secretary in September about the mishandling of his mum’s remains in India

    Relatives of victims in a fatal Air India plane crash say the Foreign Office has…

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  • International Day for the Eradication of Poverty, 17 October 2025

    International Day for the Eradication of Poverty, 17 October 2025

    On the International Day for the Eradication of Poverty, the United Nations Development Programme (UNDP) renews its resolve to eradicate poverty and advance shared prosperity. This year’s theme, “Ending social and institutional…

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  • Toddlers in Berkshire and Oxfordshire try flu vaccine trial

    Toddlers in Berkshire and Oxfordshire try flu vaccine trial

    Joe CampbellSouth of England and

    Rachel Russell

    Joe Campbell/BBC Ros and her son Eddie in a GP's room, both wearing jumpers and both with blonde/light brown hair. They are both also looking at the camera. Joe Campbell/BBC

    Ros said she wanted her son Eddie to try the vaccine ahead of winter

    Parents are being encouraged to get their toddlers involved in a new clinical trial aimed at helping lower the age…

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  • Cornish pharmacies warn funding pressures are ‘unsustainable’

    Cornish pharmacies warn funding pressures are ‘unsustainable’

    Seb NobleCornwall political reporter

    BBC An Asian woman with dark shoulder length hair wearing a black and white striped top standing in a chemist with shelves of medicines behind herBBC

    Amandip Kaur said her pharmacy in St Dennis made a loss on half of the medicines it dispenses

    A pharmacist has warned more chemists in the South West could be forced to shut because of funding pressures, without urgent action from the government.

    The National Pharmacy Association said about 27 had closed in Cornwall and Devon between October 2022 and June this year.

    Those in the industry said the cost of up to half of the medicines they have to provide was no longer covered by the amount of NHS funding they received.

    The Government said it had invested £3.1bn into pharmacies this year and they were central to its 10 year plan for the future of local healthcare.

    Amandip Kaur, from Bann’s Pharmacies Limited who run the pharmacy in St Dennis, said the current situation was “unsustainable.”

    She said: “There is no profit margin for the pharmacist and the dispensing fees we get is nothing. It really does not cover the cost of running the pharmacy.”

    She said “40 to 50 percent” of the medicines they were purchasing were not covered by the amount the NHS was paying them.

    “It really needs to be looked into by the government sooner rather than later,” she added.

    The outside of the St Dennis Pharmacy. Stone steps lead up to a glass front door of a white coloured building with a big front window with a sign with the pharmacy name on top of it.

    Owners said it was difficult to cover the running costs of independent pharmacies like in St Dennis

    Nick Kaye, a pharmacist in Newquay who represents the National Pharmacy Association said: “Up to 63 percent of our members may be at risk of closing over the next 12 months.

    “People will do loads of things to keep them going – borrow money from family members, re-mortgage, cash in pensions. Which is a really difficult situation to be in and it can be perilous.”

    He called on the government to stabilise the current situation with the cost of dispensing prescriptions.

    “The government’s own independent economic review recognized a £2.6bn shortfall in community pharmacy funding so what we really need is a roadmap to make sure that bridge is gapped over the coming years,” he added.

    ‘Largest uplift’

    A Department of Health and Social Care spokesperson said: “Community pharmacists are at the heart of local healthcare.

    “As set out in the 10 Year Health Plan we want them to play a bigger role as we shift care out of hospitals and into the community.

    “This year we increased funding to community pharmacies to almost £3.1 billion – representing the largest uplift in funding of any part of the NHS for 2025/2026 – providing patients with more services closer to home and freeing up GP appointments.”

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  • Vultron AI software simplifies federal contracting for companies

    Vultron AI software simplifies federal contracting for companies

    Vultron is designed to help users build compliant and competitive proposals for federal contracts. (Vultron)

    Vultron, a software company, is using artificial intelligence (AI) to automate proposals and compliance…

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  • Scientists make game-changing breakthrough in pursuit of futuristic fuel source: ‘This study is significant’

    Scientists make game-changing breakthrough in pursuit of futuristic fuel source: ‘This study is significant’

    Researchers in Korea have discovered a new method that could help to solve one of the biggest issues with the electrolysis process essential to creating hydrogen as an energy source.

    According to Interesting Engineering, scientists at the Korea…

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