At IDWeek 2025, held on 19-22 October, Xue Meng from ST Pharm presented results from a proof of concept clinical trial for ST Pharm’s investigational human immunodeficiency virus-1 (HIV-1) allosteric…
How do you nab a publishing deal? It’s a question that doesn’t have a singular answer. It depends on a myriad of factors (some of which—such as the current state of funding—might be outside of your control) but there are ways you can tip the…
Aston Martin has slashed £300m from its investment plans after the British sportscar maker reported a bigger than expected loss in the third quarter because of Donald Trump’s tariffs and weak demand in China.
The carmaker said on Wednesday that losses before tax were £112m in the third quarter of 2025, a ninefold increase from £12m a year earlier.
The brand, whose products are best known for featuring in the James Bond film franchise, has been buffeted by global pressures during a five-year turnaround effort that has been marked by perennial heavy losses.
Aston Martin had already warned earlier this month that this year’s profits would be lower than previously expected because of a decline in sales. It sold 1,430 cars to retailers during the third quarter of 2025, down 13% compared with the period last year.
Revenues over the first nine months of 2025 were down by 26% to £740m compared with almost £1bn a year earlier.
Adrian Hallmark, Aston Martin’s chief executive, said: “This year has been marked by significant macroeconomic headwinds, particularly the sustained impact of US tariffs and weak demand in China.
“Work is under way to review our future product cycle plan with the aim of optimising costs and capital investment while continuing to deliver innovative, class-leading products to meet customer demands and regulatory requirements.”
The manufacturer, which produces its vehicles in Warwickshire and south Wales, has already delayed the launch of its first electric model, and it cut 5% of its workforce in February. It said it would detail further changes early next year.
Aston delivered the first of its Valhalla supercars this month, which it hopes will improve the financial performance if it can deliver 150 in the last three months of the year. The company will make 999 of the mid-engined, plug-in hybrid cars, priced at £850,000 – or more than $1m a vehicle. Aston Martin said that more than half of the cars were already ordered by customers.
The company has been under the ownership of a group of investors led by the Canadian fashion tycoon Lawrence Stroll since early 2020. Stroll, who made his money through fashion brands including Michael Kors, hoped to make Aston Martin into a luxury brand to rival Italy’s Ferrari but immediately was forced to confront the crisis caused by the coronavirus pandemic.
Since then, Aston Martin has been forced to go through a painful process of reducing the number of cars held by dealers, before production issues and weak Chinese demand cause a sales slump. Then Trump came along.
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The US president imposed a 25% tariff on automobile imports on 3 April, on top of an existing 2.5% levy, causing chaos in the global car industry and adding a huge cost to Aston Martin’s cars in one of its key markets.
Demand in China also remained “extremely subdued”, Aston Martin said, because of economic weakness and the imposition of a “luxury car tariff” on more cars from the end of July.
Stroll said that 2025 had brought “several unexpected challenges” but added that his confidence in the long-term future for the brand was “unwavering”.
Peripheral afferent neurons — nerves that send signals from all areas of the body to the central nervous system (brain and spinal cord) — are known to infiltrate and grow within malignant bone tumors called osteosarcomas, often…
Turner & Townsend, the global professional services company, has appointed Cyril Delmon and Jeffrey Neervoort as the company’s data centre leads for France and the Netherlands, respectively. Both Cyril and Jeffrey will report into Niall O’Reilly, Data Centres Lead for Europe.
These appointments come at a pivotal time as the sector continues to grow at pace across Europe, driven by burgeoning demand for AI services and the increasing popularity of cloud storage solutions.
Cyril and Jeffrey’s experience will be hugely valuable as Turner & Townsend drives growth across the data centre industry, supporting clients at all stages of the project lifecycle as they contend with the complexities of the sector.
Based in France, Cyril is a seasoned Project and Programme Director with over 25 years of experience delivering large-scale infrastructure projects across critical sectors including hyperscale data centres, nuclear energy and defence.
He has led complex programmes valued over €2bn across France and internationally, supporting on acquisitions, construction and operations.
Jeffrey, who will lead the Netherlands data centre team, has seven years of experience in the data centre industry, combining operational leadership with commercial strategy and risk management expertise.
In his previous role, he oversaw service delivery for key clients across multiple countries, leading a team of over 140 people.
Turner & Townsend’s data centre team spans every major market and region, working across more than 500 data centre projects.
Having been at the forefront of data centre development for over a decade, Turner & Townsend helps clients optimise their performance and value at every stage of a programme, with its capabilities underpinned by its market-leading digital products.
Niall O’Reilly, Data Centres Lead for Europe at Turner & Townsend, said:
Cyril and Jeffrey’s appointments demonstrate our continued commitment to providing our clients with best-in-class programme and project management support in the data centre sector.
“Both bring with them deep expertise in strategic planning, procurement, operations and regulatory compliance, which will be vital as the sector continues to evolve.”
It can be fascinating to see established actors’ early work and in this British drama from 1995, we get John Simm (Life on Mars), Andrew Lincoln (The Walking Dead) and Marc Warren (Hustle), all showing early promise as lads in their late teens…
EXCLUSIVE: Robert Enright‘s Sam Pope bestseller action-thriller novels are being adapted for TV.
London- and L.A.-based Avatar Entertainment has acquired rights to the series, which comprises 15 books and follows Sam Pope, a…
Today, Sony put the PlayStation 5 Pro (PS5 Pro) on sale in the Chinese mainland market, with a price of RMB 5,599 ($770). First released overseas in November 2024, the PS5 Pro arrived in China nearly 11 months later.
Positioned as…