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  • ‘Gamechanging’ HIV prevention jab to be approved for England and Wales | Aids and HIV

    ‘Gamechanging’ HIV prevention jab to be approved for England and Wales | Aids and HIV

    A “gamechanging” injection to prevent HIV is set to be approved for use in England and Wales.

    The long-acting jab, administered every two months, will offer an alternative to the daily pills used to protect against the virus.

    This form of HIV…

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  • Ferrari cuts number of cars it sends to UK after tax changes | Automotive industry

    Ferrari cuts number of cars it sends to UK after tax changes | Automotive industry

    Ferrari has cut the number of cars it sells in the UK as wealthy individuals relocate overseas after tax changes and the abolition of non-dom status.

    The Italian luxury carmaker reportedly began limiting the number of vehicles it exported to the UK about six months ago, in an attempt to stop a decline in their residual value.

    Benedetto Vigna, the chief executive of the carmaker, said that Ferrari had seen a “stabilisation” in sales after the decision to reduce the number of vehicles it allocated to the UK.

    “Some people are getting out of that country for tax reasons,” he told the Financial Times, adding that taxes were not the only reason for the fall in residual values. “There are many different factors. Maybe when you sell to the UK, that car cannot be sold somewhere else [because of its right-hand wheel]”.

    In April the government abolished favourable tax treatment for non-domiciled residents – UK residents who declared that their long-term home was overseas to avoid paying UK taxes on global income and assets – and raised other duties on the wealthy.

    The chancellor, Rachel Reeves, told the Guardian earlier this week that talk of an exodus of wealthy residents was just “scaremongering”.

    “This is a brilliant country and people want to live here,” she said. “And I think, when people scaremonger again this year, we should take some of that with a pinch of salt.”

    Reeves, who has said that the wealthy will be one of the targets for higher taxes in next month’s budget, has previously ruled out imposing a “wealth tax” but campaigners for changes to the system have highlighted other options.

    These include raising the rate of capital gains tax, levying national insurance on rental income and on partners in law firms and consultancies, and creating higher council tax bands.

    The non-dom tax changes sparked fears that Ferrari would lose its wealthy client base, leading to volatility in its residual prices, or the expected secondhand value of a vehicle when a leasing deal comes to an end.

    Most new cars in developed markets are bought on deals that provide financing based on the amount of value a vehicle loses – its “depreciation” – rather than the overall sticker price.

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    If cars have weaker secondhand prices, the financing needed increases and the car becomes more expensive to lease.

    The residual value for Ferrari’s Purosangue model fell 12.2% between January and October, while the SF90 Stradale fell 6.6%, according to AutoTrader.

    However, prices have started to stabilise in recent months. The Ferrari 296 GTB, a supercar launched in 2022, had a recommended retail price from £256,275 if bought new. However, a used version was available from £189,490 on AutoTrader.

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  • Stanford Smartly Using AI-Generated Synthetic Data To Map And Unlock The Mysteries Of The Brain

    Stanford Smartly Using AI-Generated Synthetic Data To Map And Unlock The Mysteries Of The Brain

    In today’s column, I examine the advantageous use of AI-generated synthetic data and…

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  • Novo Nordisk shares slide as Trump vows to cut Ozempic price

    Novo Nordisk shares slide as Trump vows to cut Ozempic price

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    Novo Nordisk shares fell on Friday after Donald Trump vowed to sharply lower the price of its popular weight loss drug Ozempic as part of the US president’s drive to cut the price of medicines in America.

    Speaking at a press conference on Thursday, Trump said Ozempic’s price would be “much lower” once his administration had concluded negotiations with Novo Nordisk, the Danish group that pioneered obesity drugs.

    Trump suggested the price of the drug could fall to as low as $150. Novo Nordisk halved the US price of Ozempic for people who cannot access it with health insurance to $499 earlier this year.

    Shares in the Danish pharma group fell 5 per cent in early trading in Copenhagen on Friday. Shares in US pharma group Eli Lilly, its major rival in the obesity market, dropped 5 per cent in after-hours trading in New York.

    US patients have historically paid much higher prices for drugs than their peers in other industrialised countries. Since returning to the White House, Trump has pushed drugmakers to lower prices for American consumers, threatening import tariffs if they do not agree.

    He has complained that anti-obesity drugs are available in the UK at a fraction of their cost in the US, where branded medicines are on average two to three times more expensive than they are in Europe.

    Last month, Pfizer reached a deal with the Trump administration to lower the prices of some drugs. Eli Lilly has been widely expected to reach a deal with the White House but has yet to do so.

    Speaking alongside Trump at an event announcing a deal to lower costs of IVF treatment, Mehmet Oz, the head of the Centers for Medicare & Medicaid Services, said negotiations with Novo Nordisk were ongoing.

    “We have not negotiated those yet . . . the President will be happy with the results, and until he is we are not going to close those negotiations,” he said.

    Novo said it had “engaged in discussions” with the White House and remained “focused on improving patient access and affordability”.

    Eli Lilly has been contacted for comment.

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  • Newsroom » Carlsberg Asia and Grab Celebrate Two Years of Promoting Responsible Choices « Carlsberg Group

    Newsroom » Carlsberg Asia and Grab Celebrate Two Years of Promoting Responsible Choices « Carlsberg Group

    This September, Carlsberg Asia and Grab marked the second year of their partnership – a collaboration that is transforming how consumers across Southeast Asia enjoy beer responsibly

    Launched in late 2024, the partnership connects Carlsberg’s premium beer experiences with Grab’s vast digital ecosystem, from mobility and food delivery to dine-out offers, embedding responsible drinking messages into everyday moments.

    This strategic partnership has already yielded significant results. From January to August 2025, there has been a 37% increase in average new Carlsberg consumers per month within the Grab ecosystem (vs. same period in 2024), 22% year-on-year growth in user numbers and average uplift of 49% in Carlsberg sales, marking a 35% year-on-year increase in overall sales.

    Anchored in Carlsberg’s long-standing partnership with Liverpool F.C., the longest-running partnership in Premier League history since 1992, the collaboration has turned key football occasions into moments that combine celebration and moderation. In Singapore, the campaign culminated in September with the ‘Champion EPL Season with Carlsberg’ event, featuring Liverpool legend Robbie Fowler. Fowler toured Grab’s headquarters, rode through Orchard Road and the Civic District on an open-top bus, and met with fans, media, and VIP guests, celebrating the partnership’s success and reinforcing the message of responsible enjoyment.

    Events across Malaysia, Cambodia, Myanmar, and Singapore brought fans together both online and offline, while in-app activations on Grab offered prizes like match tickets, retro jerseys, and ride discounts promoting safe mobility.

    Following these successes, the next phase of the campaign will roll out in Vietnam later in 2025.

    “Our partnership with Grab is a powerful expression of Carlsberg’s Accelerate SAIL strategy in action,” says Arindam Varanasi, Commercial VP, Carlsberg Asia. “By combining Carlsberg’s brand strength with Grab’s reach, we’re shaping a culture where enjoyment and mindful consumption go hand in hand.”

    Through Grab’s ecosystem, including GrabFood, GrabMart, Dine Out, and mobility services, Carlsberg can reach consumers across multiple occasions, linking celebration with safety and convenience.

    The partnership will continue to expand in Vietnam and beyond later this year, building on its success to make responsible drinking a natural part of how people connect, celebrate, and enjoy life across Asia.

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  • ‘May the best win’ – Andrea Stella on Norris’ ‘repercussions’ after Oscar Piastri clash and the Drivers’ title battle

    ‘May the best win’ – Andrea Stella on Norris’ ‘repercussions’ after Oscar Piastri clash and the Drivers’ title battle

    Lando Norris and Oscar Piastri will resume their fight for the Drivers’ Championship this weekend at Austin’s Circuit of The Americas, two weeks after the McLaren duo made contact on the opening lap of the race that left Piastri asking: “Are we…

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  • Oil set for weekly loss as Trump-Putin summit looms – Reuters

    1. Oil set for weekly loss as Trump-Putin summit looms  Reuters
    2. Putin-Trump call a curveball for Zelensky ahead of White House meeting  BBC
    3. Will Putin’s call lure Trump closer to the Kremlin?  CNN
    4. Trump says he will meet Putin again after making…

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  • Experience: I am the air guitar world champion | Life and style

    Experience: I am the air guitar world champion | Life and style

    I was 10 when I read an article in the local paper about the Air Guitar World Championships, which take place every year in my home town of Oulu, Finland. My parents had helped out at the very first contest back in 1996 – my mum gave out…

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  • When Healing Turns Harmful: Adrenal Support Cells Tied To Cancer Origin

    When Healing Turns Harmful: Adrenal Support Cells Tied To Cancer Origin

    “In tumors with germline VHL mutations, subsets of these support cells showed loss of chromosome 3p, the ‘second hit’ leading to VHL inactivation. This suggests they may be the origin of certain tumors,” says Dr. Michael Mints , docent at the…

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  • All Pokemon Legends ZA Mega Stones Locations

    All Pokemon Legends ZA Mega Stones Locations

    Pokemon Legends ZA is out, and the game is filled with plenty of Megas, which are insanely strong. For the first time in the series, wild Pokemon can Mega Evolve on their own, and the wildest part is that they can KO your creature before…

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