Blog

  •  Early MRI Detection in Frontotemporal Dementia

     Early MRI Detection in Frontotemporal Dementia

    A MAJOR international study has shown that new brain imaging techniques can detect early signs of frontotemporal dementia before brain shrinkage or symptoms arise. Researchers found that changes in cortical microstructure, rather than cortical…

    Continue Reading

  • Freightos Reports KPIs for Third Quarter of 2025 Exceeding Management Expectations

    Freightos Reports KPIs for Third Quarter of 2025 Exceeding Management Expectations

    The Company Plans To Report Earnings on November 17, 2025

    BARCELONA, Spain, Oct. 20, 2025 /PRNewswire/ – Freightos Limited (NASDAQ: CRGO), the leading digital freight booking and payment platform for the international freight industry, today reported preliminary key performance indicators for the third quarter of 2025, highlighting the continued industry adoption of digital solutions to enhance efficiency and resilience in global supply chains.

     


    Actuals*

    Management’s Expectations


    Q3 2025

    Q3 2025




    # Transactions (‘000)

    429

    419 – 425

    Year over Year Growth

    27 %

    24% – 25%

    GBV ($m)

    336

    329 – 333

    Year over Year Growth

    54 %

    51% – 53%

    *Numbers are preliminary and subject to change with the full earnings release

    Platform Expansion and Network Growth

    Freightos continued its robust expansion in Q3 2025, achieving the 23rd consecutive quarter of record transactions and reinforcing the platform’s value as the industry’s digital transformation platform connecting global trade participants.

    • Transactions: 429k Transactions in Q3 2025 representing a 27% year-over-year growth, exceeding management’s expectations. The WebCargo platform, connecting carriers and freight forwarders, continued to lead transactions growth, with the carrier portal component delivering high growth rate.
    • Carrier and Buyer Growth: In Q3 2025, 77 carriers were active on Freightos’ platforms with more than five bookings. Newly active carriers this quarter included both flag-carrier belly-cargo operators and niche cargo specialists, with some added through regional GSAs, reflecting the platform’s expanding reach across global and local networks. With most major airlines already connected to the platform, new airline additions are increasingly regional or niche airlines, with further expansion expected as smaller carriers advance their digital readiness. Meanwhile, unique buyer users reached 20,600. This reflected growth in WebCargo users partially offset by some reduction in SMB North American custom clearance users due to market uncertainty.
    • Gross Booking Value (GBV): Carriers and freight forwarders selling on Freightos’ platform derived $336 million of revenue from the platform in Q3 2025, representing a 54% year-over-year increase. The major contributors to GBV growth were WebCargo and the portal, mirroring growth in transactions highlighted by the relatively high GBV per transaction in the portal component.

    “The powerful network effects of our platform are clearly visible in this quarter’s KPIs,” said Zvi Schreiber, CEO of Freightos. “As the leading digital freight booking platform, Freightos creates a virtuous cycle where each new participant – whether carrier, forwarder, or shipper – enhances the value for all others. Our expanding ecosystem enables unprecedented connectivity and efficiency across the global freight landscape, transforming what was once a fragmented, manual process into a streamlined digital experience. This growing adoption confirms our vision that digitization is becoming the new standard in international freight, supporting more efficient world trade.”

    Q3 2025 Earnings Call

    Financial results for the second quarter 2025 will be reported before markets open on November 17, 2025. Freightos’ management will host a webcast and conference call to discuss the results that morning at 8:30 a.m. EDT.

    Information about Freightos’ financial results, including a link to the live webcast, will be available on Freightos’ investor relations website at https://www.freightos.com/investor-news/.

    To participate in the call, please register at the following link: https://freightos.zoom.us/webinar/register/WN_A2xWbYIrRz6lnetBZP8_7Q#/registration

    Following registration, you will be sent the link to the conference call which is accessible either via the Zoom app, or alternatively from a dial-in telephone number.

    Questions may be submitted in advance to [email protected] or via Zoom during the call.

    A replay of the webcast, as well as the call’s transcript, will be available on Freightos’ Investor Relations website following the call.

    Glossary

    We have provided below a glossary of certain terms used in this press release:

    • Carriers: Number of unique air and ocean carriers, mostly airlines, that have been sellers of transactions. For airlines, we count booking carriers, which include separate airlines within the same carrier group. We do not count dozens of other airlines that operate individual segments of air cargo transactions, as we do not have a direct booking relationship with them. Carriers include ocean less-than-container load (LCL) consolidators. In addition, we only count carriers when more than five bookings were placed with them over the course of a calendar quarter.
    • Unique buyer users: Number of individual users placing bookings, typically counted based on unique email logins. The number of buyers, which counts unique customer businesses, does not reflect the fact that some buyers are large multinational organizations while others are small or midsize businesses. Therefore, we find it more useful to monitor the number of unique buyer users than the number of buyer businesses.
    • GBV: Total value of transactions on the Freightos platform, which is the monetary value of freight and related services contracted between buyers and sellers on the Freightos platform, plus related fees charged to buyers and sellers, and pass-through payments such as duties. GBV is converted to U.S. dollars at the time of each transaction on the Freightos platform. This metric may be similar to what others call gross merchandise value (GMV) or gross services volume (GSV). We believe that this metric reflects the scale of the Freightos platform and our opportunities to generate platform revenue.
    • Transactions: Number of bookings for freight services, and related services, placed by Buyers across the Freightos platform with third-party sellers and with Clearit. Sellers of Transactions include Carriers (that is, airlines, ocean liners and LCL consolidators) and also other providers of freight services such as trucking companies, freight forwarders, general sales agents, and air master loaders. The number of transactions booked on the Freightos platform in any given time period is net of transactions that were canceled prior to the end of the period. Transactions booked on white label portals hosted by Freightos are included if there is a transactional fee associated with them.

    About Freightos

    Freightos® (Nasdaq: CRGO) is the leading vendor-neutral global freight booking platform. Airlines, ocean carriers, thousands of freight forwarders, and well over ten thousand importers and exporters connect on Freightos, making world trade efficient,  agile, and resilient.

    The Freightos platform digitizes the trillion dollar international freight industry, supported by a suite of software solutions that span pricing, quoting, booking, shipment management, and payments for businesses of all shapes and sizes around the globe. Products include Freightos Enterprise for multinational importers and exporters, Freightos Marketplace for small importers and exporters, WebCargo and 7LFreight by WebCargo for freight forwarders, WebCargo for Airlines, and Clearit, a digital customs broker.

    Freightos is a leading provider of real-time industry data via Freightos Terminal, which includes the world’s leading spot pricing indexes, Freightos Air Index (FAX) for air cargo and Freightos Baltic Index (FBX) for container shipping. Futures of FBX are traded on CME and SGX.

    More information is available at freightos.com/investors.

    Contacts

    Media:
    Tali Aronsky
    [email protected]

    Investors:
    Anat Earon-Heilborn
    [email protected]

    Logo – https://mma.prnewswire.com/media/2319256/4496202/Freightos_Logo.jpg 

    SOURCE Freightos

    Continue Reading

  • Oasis, Benedict Cumberbatch Films Interview With Dylan Southern: LFF

    Oasis, Benedict Cumberbatch Films Interview With Dylan Southern: LFF

    Benedict Cumberbatch stars in The Thing With Feathers, writer-director Dylan Southern’s big-screen adaptation of Max Porter’s award-winning Grief Is the Thing With Feathers, which just screened at the 69th edition of the BFI London Film…

    Continue Reading

  • How often are stars flung out of the center of the Galaxy? – Sciworthy

    How often are stars flung out of the center of the Galaxy? – Sciworthy

    The Earth, Moon, and Sun form a stable 3-body system, but there is no simple equation one can apply to 3-body systems to predict their orbits. This 3-body problem becomes increasingly complicated as more objects are added to the system…

    Continue Reading

  • Asus Targets Creators With First-Ever 8K HDR Mini-LED Display – extremetech.com

    1. Asus Targets Creators With First-Ever 8K HDR Mini-LED Display  extremetech.com
    2. ASUS Announces October Availability of ProArt Display 8K PA32KCX  ASUS Pressroom
    3. ASUS Introduces ProArt PA32KCX; World’s First 8K HDR Mini LED Monitor For…

    Continue Reading

  • Viet Nam’s labour statistics: From modernization to global alignment

    Viet Nam’s labour statistics: From modernization to global alignment

    Over the past decade and a half, Viet Nam has transformed the way it measures and understands work. From simple employment counts to a comprehensive, internationally comparable system, labour statistics in Viet Nam have become a cornerstone for evidence-based and gender responsive policymaking and sustainable development.

    A decade of transformation and international alignment

    The early 2010s marked a turning point for Viet Nam’s statistical system. Recognizing the growing complexity of the labour market in a rapidly developing economy, the National Statistics Office (NSO) embarked on a far-reaching modernization process.

    The introduction of the Labour Force Survey on a quarterly basis in 2011 was a major milestone. For the first time, Viet Nam could monitor employment trends, unemployment, and labour underutilization in near real time. This shift from annual to quarterly data collection not only improved accuracy but also enhanced the government’s ability to respond to economic shifts and social challenges.

    Viet Nam’s commitment to aligning its data with global standards quickly positioned it as a country with advanced labour statistics. The NSO worked closely with ASEAN partners, the ILO, and international experts to harmonize definitions, methodologies, and indicators. 2025 also marks the fifth year applying 19th International Conference of Labour Statisticians standards advancing Viet Nam’s labour statistics – a move that redefined how employment, work, and labour underutilization were measured worldwide. The adoption of internationally comparable labour market indicators allowed Viet Nam to contribute actively to global databases and to monitor progress toward the Sustainable Development Goals, particularly Goal 8 on decent work and economic growth.

    This progress has made Viet Nam one of the few developing countries in Asia capable of producing timely, high-quality and gender responsive labour statistics that meet global comparability standards – an achievement widely recognized by international partners.

    Data responding to quick changes in the labour market

    The true value of a robust statistical system often becomes clear in times of uncertainty. When the pandemic struck in 2020, Viet Nam’s quarterly LFS and well-trained statistical network proved essential. Within months, the NSO was able to produce special reports capturing the pandemic’s impact on jobs, income, and informal employment – data that guided targeted government interventions and social support measures.

    Among the most important advances – and clear examples of how labour statistics in Viet Nam have kept pace with a rapidly changing labour market – are the explicit measurement and reporting of informal employment and the pilot measurement of digital platform work. Recognizing that more people are doing work mediated by digital platforms – whether ride-hailing, delivery, freelancing, or online provision of services – Viet Nam has begun exploring how to capture this in its labour statistics. This pilot work positions Viet Nam as one of the first countries in Asia to take early steps in capturing the platform economy in official labour data.

    This proactive approach shows that Viet Nam’s statistical system is not only robust, but also responsive and forward-looking, ensuring that data remain relevant and timely in reflecting the evolving world of work.

    Digital transformation and innovation

    In recent years, Viet Nam has continued to push forward with digital transformation in data collection and analysis. The NSO has introduced computer-assisted personal interviewing (CAPI), expanded the use of administrative data, connecting with other databases. The NSO also starts to introduce artificial intelligence to some stages of data management. Noticeably, artificial intelligence has been applied to data cleaning and automatic classification of data. These innovations improve not only the quality of data but also the efficiency of the whole statistical system responding timely to the rise of the digital age. 

    Felix Weidenkaff, Officer-In-Charge of the ILO Viet Nam participates in the Commemorative Ceremony and High-Level Forum in Viet Nam for World Statistics Day

    Looking ahead

    As Viet Nam moves toward a digital and knowledge-driven economy, the demand for high-quality, timely, and disaggregated labour data will continue to grow. The NSO’s ongoing efforts to modernize surveys, apply artificial intelligence in data processing, and enhance data integration are laying the groundwork for the next generation of labour statistics.

    The success of Viet Nam’s labour statistics rests on strong partnerships with national and international organizations. Together, these partners have worked to strengthen the technical capacity of national statisticians, improve data dissemination, and promote the use of statistics for informed decision-making. Viet Nam has also become an active contributor to regional and global discussions on labour measurement, sharing experiences that inspire neighbouring countries.

    On this World Statistics Day, Viet Nam’s achievements remind us that statistics are not just numbers – they are a foundation for understanding people’s lives, shaping fairer policies, and building a more inclusive future. As the world marks this day under the global theme of Driving Change with Quality Statistics and Data for Everyone, Viet Nam’s progress in labour statistics stands as a vivid example of that vision in action – ensuring that every number tells a story, and every story helps build a stronger nation.

    Continue Reading

  • DNA ‘flower’ robots react to environment and deliver drugs

    DNA ‘flower’ robots react to environment and deliver drugs

    These ‘DNA flowers’ were developed by a team at the University of North Carolina at Chapel Hill and are made from crystals formed by combining DNA and inorganic materials. They can reversibly fold and unfold…

    Continue Reading

  • BD Launches New AI-enabled Solutions to Drive Connectivity Across Healthcare Settings

    BD Launches New AI-enabled Solutions to Drive Connectivity Across Healthcare Settings

    BD Launches New AI-enabled Solutions to Drive Connectivity Across Healthcare Settings

    FRANKLIN LAKES, N.J., Oct. 20, 2025 /PRNewswire/ — BD (Becton, Dickinson and Company) (NYSE: BDX), a global leader in medical technology, introduces the BD Incada™ Connected Care Platform, a new scalable, AI-enabled, cloud-based platform that unifies BD device data into one intelligent ecosystem for the first time. The BD Incada™ Platform is available now with the launch of the next-generation BD Pyxis™ Pro Automated Medication Dispensing Solution, creating enterprise-wide visibility and connectivity that transforms data into actionable insight.  

    “Our vision for the BD Incada™ Platform is to go beyond legacy connectivity to create meaningful connections across devices from infusion pumps to patient monitors to pharmacy robotics, and unify data from those solutions into one ecosystem, transforming data into clear, actionable insights for care teams,” said Bilal Muhsin, EVP and President of BD Connected Care. “These launches represent key milestones in BD’s Connected Care strategy, where we are uniquely positioned with our broad portfolio from pharmacy to bedside, to leverage game-changing technology to drive meaningful benefits for our customers.”

    AI-powered analytics to drive smarter, faster decisions

    Built on Amazon Web Services’ (AWS) on-demand cloud computing infrastructure, the BD Incada™ Platform leverages the latest in AI technologies, such as natural language search in analytics, and is scalable to meet the data volumes created by nearly 3 million smart connected BD devices. With Analytics in the BD Incada™ Platform, data from BD’s leading medication management solutions now flows through a secure, cloud platform and enables:

    • Enterprise-wide visibility into medication inventory, which helps clinicians identify patterns and ensure medication availability, reduce medication waste and improve labor efficiency
    • The ability to ask natural language questions and receive AI-powered insights and analytics on demand
    • User-customizable dashboards that empower frontline clinical teams to act on insights quickly

    Flexible, secure storage to get the right medication to the right patient, faster

    The new BD Pyxis™ Pro Dispensing Solution delivers smarter, more secure medication storage, which enables faster access at the point of care. The first-of-its-kind flexible, stackable device configuration offers more medication storage capacity to improve medication availability from refrigerated to ambient storage. The BD Pyxis™ Pro Dispensing Solution allows hospitals and health systems to easily adapt to the evolving needs of their patient populations, with features including:

    • Expanded capacity in a similar footprint, enabling clinicians to add up to 538 multi-access or 98 secure pockets without taking more space in their medication rooms
    • Enhanced security features to improve controlled substance management and medication safety efforts
    • More efficient access, with RFID badge scanning, wireless barcode scanners and illuminated bins to streamline medication retrieval

    “For over 35 years, the BD Pyxis™ System has been the backbone of medication management across hospitals and health systems, with more than 9.8 million transactions on BD Pyxis™ devices every day,” said Connor Bates, Worldwide President for Medication Management Solutions at BD. “With the enhanced secure capacity, durability and AI-powered analytics of the next-generation BD Pyxis™ Pro Dispensing Solution, we’re ushering in a transformative new era for medication management.”

    Together, the BD Incada™ Platform and BD Pyxis™ Pro Dispensing Solution sets a new standard for unified, data-driven healthcare operations.

    About BD
    BD is one of the largest global medical technology companies in the world and is advancing the world of health by improving medical discovery, diagnostics, and the delivery of care. The company supports the heroes on the frontlines of health care by developing innovative technology, services and solutions that help advance both clinical therapy for patients and clinical process for health care providers. BD and its more than 70,000 employees have a passion and commitment to help enhance the safety and efficiency of clinicians’ care delivery process, enable laboratory scientists to accurately detect disease and advance researchers’ capabilities to develop the next generation of diagnostics and therapeutics. BD has a presence in virtually every country and partners with organizations around the world to address some of the most challenging global health issues. By working in close collaboration with customers, BD can help enhance outcomes, lower costs, increase efficiency, improve safety, and expand access to health care. For more information on BD, please visit bd.com or connect with us on LinkedIn at www.linkedin.com/company/bd1/, X (formerly Twitter) @BDandCo or Instagram @becton_dickinson. 

    Contacts:
                                                                

    Media

    Investors:

    Fallon McLoughlin                                                   

    Adam Reiffe

    Director, Public Relations                                         

    VP, Investor Relations

    201.258.0361                                                           

    201.847.6927

    fallon.mcloughlin@bd.com                                       

    adam.reiffe@bd.com       

     

    BD (Becton, Dickinson and Company) Logo (PRNewsfoto/BD (Becton, Dickinson and Company))

    SOURCE BD (Becton, Dickinson and Company)


    Continue Reading

  • Effects of ultrasound-guided adductor canal block at different volumes on postoperative analgesia management in patients undergoing total knee arthroplasty: a prospective clinical study | BMC Anesthesiology

    Effects of ultrasound-guided adductor canal block at different volumes on postoperative analgesia management in patients undergoing total knee arthroplasty: a prospective clinical study | BMC Anesthesiology

    Study design

    This randomized, prospective study included 90 patients, aged between 18 and 65, with ASA classification I-II-III, who were scheduled for total knee arthroplasty surgery under spinal anesthesia. Patients with a history of bleeding diathesis, receiving anticoagulant treatment, allergies or sensitivity to local anesthetics and opioid drugs, patients with infection in the area where the block will be applied, pregnancy suspicion, pregnant or breastfeeding mothers, and patients who did not accept the procedure were excluded from the study. Ethical approval was obtained from the Bursa City Hospital Ethics Committee on 07.12.2022, protocol number 2022-17/3. Our study was registered on https://clinicaltrials.gov/ with the number NCT06084403. The patient recording and disribution were illustrated by the Consolidated Standards of Reporting Trials (CONSORT) flowchart (Fig. 1).

    Fig. 1

    CONSORT flow diagram of the study

    Patients were randomized into three groups, each containing 30 patients, using a computer program (Group 20 = group receiving ACB with 20 ml, Group 30 = group receiving ACB with 30 ml, Group 40 = group receiving ACB with 40 ml). The practitioners were blind to the data collection, and patients did not know which volume was applied. Postoperative pain scores and opioid consumption were recorded by a pain technician who was blind to the study.

    Anesthesia application

    After the patients were taken to the operating room, standard monitoring (electrocardiography, noninvasive arterial blood pressure, and peripheral oxygen saturation) was performed, and premedication was administered with 2 mg intravenous midazolam. For spinal anesthesia, the patients were positioned sitting, and following the necessary asepsis and antisepsis rules, a 25-gauge pencil-point spinal needle (B.Braun, Melsungen, Germany) was inserted into the subarachnoid space through a median approach from L3-4 or L4-5. After observing free clear cerebrospinal flow, 15 mg of hyperbaric bupivacaine was administered. To prevent postoperative nausea and vomiting, 4 mg of ondansetron was given intravenously. Total knee arthroplasty surgery was performed by the same surgical team using the same surgical procedure.

    Block interventions

    The block procedure was performed after the surgery was completed. All adductor canal blocks were performed by two experienced anesthesiologists with advanced clinical expertise in regional anesthesia. After ensuring aseptic conditions, a high-frequency linear ultrasound probe (GE ML6-15-D Matrix Linear, Boston, USA) was covered with a sterile sheath, and a 100 mm block needle (Stimuplex Ultra®, Braun, Melsungen, Germany) was used. The linear ultrasound probe was placed medial to the patella, and the probe was advanced cephalad to visualize the femoral artery, the adductor hiatus, and the apex of the femoral triangle. Then, 5 ml of saline was injected under ultrasound guidance into the midpoint of the adductor canal to confirm the block site (Fig. 2). Then, local anesthetic solution containing bupivacaine at 0.25% concentration was administered as 20 ml in Group 20, 30 ml in Group 30, and 40 ml in Group 40.

    Fig. 2
    figure 2

    A Adductor canal sonographic anatomy. Sartorius Muscle, A; artery, V; vein. B Sonographic anatomy of block. Needle direction, and spread of local anesthetic during block performing. A; artery

    After the operation, patients were taken to the postoperative recovery room. Patients reaching a score of 9 on the Aldrete scoring system were transferred to the ward.

    Postoperative analgesia management

    All patients received 0.5 mg/kg of intravenous tramadol and 20 mg of tenoxicam 30 min before the end of the surgical procedure. In the postoperative period, patients received 20 mg of tenoxicam intravenously twice a day. A patient-controlled analgesia (PCA) device was connected to all patients as soon as they were taken to the recovery room. The PCA was prepared with tramadol at a concentration of 5 mg/ml, with a lockout interval of 20 min and a bolus dose of 10 mg without a basal infusion. During the ward follow-ups, hourly NRS scores were monitored. If the NRS score was 4 or above, 0.5 mg/kg of intravenous meperidine was administered as a rescue analgesic. NRS scores at designated times as well as rescue analgesic needs and hours were noted in detail.

    Postoperative pain assessment was performed using the NRS scoring system (0 = no pain, 10 = worst pain imaginable). Resting and moving NRS scores were evaluated and recorded at 2, 4, 8, 16, 24, and 48 h. If the NRS score was ≥ 4, 0.5 mg/kg of intravenous meperidine was administered as a rescue analgesic.

    Motor block was evaluated using the modified Bromage scale (0: can move leg, foot, and knee freely; 1: normal knee and foot movements, but cannot raise leg straight; 2: cannot flex knee; 3: cannot move foot and knee) [8]. The need for rescue analgesics, postoperative opioid consumption, and side effects such as nausea, vomiting, and itching, as well as complications that may arise due to the block, were recorded.

    Sample size calculation

    The sample size calculation was performed using G*Power software version 3.1.9.2 (Kiel University, Kiel, Germany). Power analysis based on preliminary data on total opioid consumption [Group 20: 107.86 ± 42.17 (n = 7), Group 30: 88.57 ± 50.14 (n = 7), Group 40: 50.14 ± 51.2 (n = 7)] showed an effect size of 0.49, with a 95% confidence interval, an alpha error of 0.05, and a power of 0.95. Based on this effect size and confidence interval, a sample size of 22 patients per group was calculated to be sufficient. To account for potential dropouts, 30 patients were planned to be enrolled in each group.

    Statistical analysis

    Statistical analysis was performed with IBM SPSS v20.0 (SPSS Inc., Chicago, Illinois, USA) software package. The normality distribution of variables was checked with the Kolmogorov-Smirnov and histogram tests. Descriptive data were expressed as median [%25–75] and a number. Categorical variables were expressed as a number and analysed using the Chi-square and Fisher exact tests. Non-normally distributed continuous variables were analyzed using the Kruskal-Wallis test, followed by Dunn’s test for post-hoc analysis to assess differences among groups. For the statistical analysis, p < 0.05 was considered statistically significant.

    Continue Reading

  • Paydirt Games Inc closes $2M Series A to launch first PC game title Fatal Frontier 1869 this Fall

    Paydirt Games Inc closes $2M Series A to launch first PC game title Fatal Frontier 1869 this Fall

    Paydirt Games first game Fatal Frontier 1869 launches this Fall on PC

    Paydirt Games, Inc. announces $2M Series A bringing total funding north of $3.5M with first PC game title Fatal Frontier 1869 launching late Fall 2025

    PC gamers have both…

    Continue Reading