Blog

  • Boosting SCN2A expression reduces seizures in mice

    Boosting SCN2A expression reduces seizures in mice

    By compensating for a missing copy of SCN2A, one of the genes most strongly linked to autism, a variant of the gene-editing technology CRISPR can reduce susceptibility to seizures, according to a new study in mice.

    SCN2A…

    Continue Reading

  • Currency gains help to relieve inflationary pressures in sub-Saharan Africa

    Currency gains help to relieve inflationary pressures in sub-Saharan Africa

    A number of economies in sub-Saharan Africa have seen
    inflationary pressures wane in recent months amid currency
    appreciation versus the US dollar. In turn, this is allowing
    central banks to lower interest rates, helping business activity in
    the region to expand solidly. PMI® data and the anecdotal evidence
    provided by our survey respondents can help to illustrate the
    impact of currency movements.

    Range of currencies gain versus the US dollar in 2025

    Of the seven economies in sub-Saharan Africa for which S&P
    Global compile PMI surveys, five have seen currency appreciation
    against the US dollar over the course of 2025 so far. While this to
    some extent reflects the weakness of the dollar itself this year,
    there have also been positive factors supporting local currencies,
    including support from IMF programmes, fiscal consolidation and
    tight monetary policy.

    In particular, the Ghanaian cedi and Zambian kwacha have each
    appreciated by 15% against the US dollar in 2025 so far, while the
    South African rand and Nigerian naira have also seen gains.

    Currency appreciation has contributed to a sustained easing of
    inflationary pressures in the sub-Saharan Africa business sector.
    PMI data showed that overall input costs increased at the slowest
    pace since the COVID-19 pandemic in September. While selling prices
    rose at a slightly faster pace than in August, here too the pace of
    inflation was among the weakest in the past five years.

    Country level PMI data show that most of the economies we cover
    in sub-Saharan Africa have seen either a slowdown in inflation of
    purchase costs or outright falls in prices over the course of 2025.
    Those countries seeing the strongest currency appreciations against
    the US dollar – Ghana and Zambia – have recorded periods of
    decreasing purchase prices. Such price falls are rarely seen among
    the sub-Saharan Africa PMIs, which normally suffer from marked
    inflationary pressures. Even Nigeria, where purchase costs
    continued to rise sharply during the third quarter, posted the
    weakest pace of inflation since March 2020.

    Survey comments highlight impact of currency gains

    Anecdotal evidence from our PMI surveys can help us to see what
    is driving the drop in price pressures in the region, with comments
    from panellists highlighting the impact of currency appreciation on
    purchase costs.

    Normally we see any references to exchange rates or the dollar
    being linked to rises in purchase prices as downward pressure on
    local currencies feeds through to higher costs for imported items
    and those priced in dollars. But between June and August this year
    we recorded more mentions of these factors pushing down
    prices rather than lifting them; the only time this has been the
    case since we have had the full complement of seven sub-Saharan
    Africa PMI surveys.

    Similarly, recent months have seen above-average mentions of
    either exchange rates or the dollar causing a drop in purchase
    prices, to a degree second only to that seen in April 2024, when
    firms in Kenya were responding to a substantial appreciation of the
    shilling against the US dollar.

    Central banks lower interest rates amid waning inflation

    Easing inflationary pressures have enabled central banks across
    much of the region to lower their interest rates over the course of
    2025. Of the seven economies we cover, five have lower levels of
    interest rates now than at the start of the year. Most notably is
    Ghana, where the central bank has cut rates by 650 basis points in
    the past two meetings. Interest rates in Uganda are at the same
    level as they were at the start of 2025, while only Zambia has
    posted an increase. Here though, S&P Global Market Intelligence
    expects a cut of 50-100 basis points at the upcoming November
    monetary policy committee meeting.

    Output rises solidly at end of third quarter

    The softening inflation environment has coincided with a period
    of solid growth in the sub-Saharan Africa private sector. September
    saw output increase at the fastest pace in five months in response
    to higher inflows of new orders. Employment rose for the twelfth
    month running, while firms increased their purchasing activity and
    inventory holdings.

    Most notably, the Stanbic Bank Zambia PMI signalled the fastest
    rise in business activity since June 2023, while Stanbic Bank PMI
    data for Kenya signalled a return to growth following mid-year
    disruptions caused by protests. The only economy covered by PMI
    data to see a drop in output during September was Ghana, but even
    here new orders expanded and business confidence remained elevated,
    meaning that we could potentially see renewed growth in the months
    ahead.

    Overall, the sub-Saharan Africa private sector enters the final
    quarter of the year on a solid footing, in part at least due to the
    currency gains seen over the course of 2025 so far.

    Access the global PMI press releases.

    Andrew Harker, Economics Director, S&P Global Market
    Intelligence

    Tel: +44 134 432 8196

    andrew.harker@spglobal.com

    © 2025, S&P Global. All rights reserved. Reproduction in
    whole or in part without permission is prohibited.


    Purchasing Managers’ Index™ (PMI®) data are compiled by S&P Global for more than 40 economies worldwide. The monthly data are derived from surveys of senior executives at private sector companies, and are available only via subscription. The PMI dataset features a headline number, which indicates the overall health of an economy, and sub-indices, which provide insights into other key economic drivers such as GDP, inflation, exports, capacity utilization, employment and inventories. The PMI data are used by financial and corporate professionals to better understand where economies and markets are headed, and to uncover opportunities.

    Learn more about PMI data

    Request a demo


    This article was published by S&P Global Market Intelligence and not by S&P Global Ratings, which is a separately managed division of S&P Global.

    Continue Reading

  • Changes in the gastric microbiota linked to growth of neuroendocrine tumors

    Changes in the gastric microbiota linked to growth of neuroendocrine tumors

    Researchers from Osaka Metropolitan University have discovered how the balance of bacteria in the stomach affects the growth of neuroendocrine tumors (NETs). By identifying the specific bacteria involved and the biochemical…

    Continue Reading

  • Govt notifies draft amendments for civil servant asset declarations to meet IMF demands

    Govt notifies draft amendments for civil servant asset declarations to meet IMF demands

    The government has notified draft amendments to the Sharing of Assets of Civil Servants Rules, 2023, on Wednesday, as part of efforts to fulfill the IMF’s governance reform requirements, according to a news report. 

    The new rules mandate…

    Continue Reading

  • OpenAI expands ‘ChatGPT Go’ availability to 16 Asian countries

    OpenAI expands ‘ChatGPT Go’ availability to 16 Asian countries

    Philippines – After debuting in India and Indonesia, OpenAI has expanded its cost-friendly subscription plan, ‘ChatGPT Go’, to 16 countries across Asia, aiming to make access to its GPT-5 model more affordable and widely…

    Continue Reading

  • Surgical menopause associated with higher risk of workforce exit

    Surgical menopause associated with higher risk of workforce exit

    Menopause before the age of 45 (known as early menopause) is associated with an increased risk of an array of serious diseases, including cardiovascular disease and osteoporosis. A new study suggests that it may also force women out…

    Continue Reading

  • Brains of Stranded Dolphins Showed Signs of Alzheimer’s Disease : ScienceAlert

    Brains of Stranded Dolphins Showed Signs of Alzheimer’s Disease : ScienceAlert

    Might brain damage linked to Alzheimer’s be one of the reasons dolphins lose their way and end up stranded? It’s a possibility explored in a new study of 20 common bottlenose dolphins (Tursiops truncatus) stranded in the Indian River Lagoon,…

    Continue Reading

  • Prognostic value of low-cost white blood cell indices and procalcitonin for mortality in Rwandan sepsis patients: a prospective intensive care unit study | Tropical Medicine and Health

    Prognostic value of low-cost white blood cell indices and procalcitonin for mortality in Rwandan sepsis patients: a prospective intensive care unit study | Tropical Medicine and Health

    A total of 125 patients were followed up over 40 days. Of these, 56 (44.8%) were females and 67 (53.6%) were males. The proportion of deaths was marginally higher among males (56.7%) compared to females (50.0%), although this difference did not…

    Continue Reading

  • China tightens export rules for crucial rare earths

    China tightens export rules for crucial rare earths

    China has tightened its rules on the export of rare earths – the elements that are crucial to the manufacture of many high-tech products.

    New regulations announced by the country’s Ministry of Commerce formalise existing rules on processing technology and unauthorised overseas cooperation.

    China is also likely to block exports to foreign arms manufacturers and some semiconductor firms.

    Rare earth exports are a key sticking point in the months-long negotiations between Beijing and Washington over trade and tariffs. The announcement comes as China’s President Xi Jinping and his US counterpart Donald Trump are expected to meet later this month.

    Technology used to mine and process rare earths, or to make magnets from rare earths, can only be exported with permission from the government, the Ministry of Commerce said.

    Many of these technologies are already restricted. China had added several rare earths and related material to its export control list in April, which caused a major shortage back then.

    But the new announcement makes clear that licenses are unlikely to be issued to arms manufacturers and certain companies in the chip industry.

    Chinese firms are also banned from working with foreign companies on rare earths without government permission.

    China has been accused by the US and other Western countries of aiding Russia’s war on Ukraine by allowing dual technology exports – materials that can be used for either civilian or military purposes – to be sent to Moscow. Beijing has repeatedly denied this.

    The latest announcement also clarifies the specific technologies and processes that are restricted.

    These include mining, smelting and separation, magnetic material manufacturing, and recycling rare earths from other resources.

    The assembly, debugging, maintenance, repair, and upgrading of production equipment are also prohibited from export without permission, the announcement added.

    This could have an impact on the US, which has a significant rare earths mining industry but lacks processing facilities.

    Rare earths are a group of 17 chemically similar elements that are crucial to the manufacture of many high-tech products.

    Most are abundant in nature, but they are known as “rare” because it is very unusual to find them in a pure form, and they are very hazardous to extract.

    Although you may not be familiar with the names of these rare earths – like neodymium, yttrium and europium – you will be very familiar with the products that they are used in.

    For instance, neodymium is used to make the powerful magnets used in loudspeakers, computer hard drives, electric car motors and jet engines that enable them to be smaller and more efficient.

    China has a near monopoly on extracting rare earths as well as on refining them – which is the process of separating them from other minerals.

    The International Energy Agency (IEA) estimates that China accounts for about 61% of rare earth production and 92% of their processing.

    Additional reporting by Ian Tang of BBC Monitoring.

    Continue Reading

  • Many men receive frequent prostate cancer tests without symptoms

    Many men receive frequent prostate cancer tests without symptoms

    Current prostate specific antigen (PSA) testing “may not effectively target testing to those most likely to benefit, raising concerns about overtesting” warn researchers from the University of Oxford in a study of over 10 million…

    Continue Reading