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  • Shared Molecular Pathways Link IPF and RA-Associated Lung Disease

    Shared Molecular Pathways Link IPF and RA-Associated Lung Disease

    A multicenter study published in Arthritis & Rheumatology shows that a blood-based biomarker panel originally developed for idiopathic pulmonary fibrosis (IPF) may identify patients with rheumatoid arthritis (RA) at higher risk of interstitial…

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  • Hyundai gets the conversation going on Threads

    Hyundai gets the conversation going on Threads

    Communication with a creative twist

    A continual array of exciting Threads features and functions boosts engagement and fun. Hyundai’s approach is always open, inclusive, and curious, emphasizing authenticity and genuine enjoyment. New…

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  • AI Helps Gamified Social Learning for People With Autism

    AI Helps Gamified Social Learning for People With Autism

    A study published in Nature explores how large language models (LLMs) can assist in social learning for individuals with autism  through a gamified training environment. The research focuses on whether LLMs, specifically GPT-4o, can accurately…

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  • Australia's Mayne Pharma falls as treasurer considers blocking Cosette's $437 million bid – Reuters

    1. Australia’s Mayne Pharma falls as treasurer considers blocking Cosette’s $437 million bid  Reuters
    2. Chalmers all but kills Mayne Pharma takeover bid  AFR
    3. Mayne Pharma Faces Scrutiny Over Cosette Acquisition  Sharecafe
    4. Australian treasurer weighs blocking Mayne Pharma’s $437 million takeover  TradingView
    5. All Ords drug maker’s shares plunge 30% on takeover troubles  The Motley Fool Australia

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  • ‘It … was burning when found’

    ‘It … was burning when found’

    Mine workers in Western Australia found a “smoking slab” speculated to be part of the upper stage of a Chinese space rocket that fell back to Earth, according to Space.com.

    What’s happening?

    On October 18, workers found a smoldering slab of metal…

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  • Aquarian Holdings nears $4bn deal to take US insurer Brighthouse private

    Aquarian Holdings nears $4bn deal to take US insurer Brighthouse private

    Stay informed with free updates

    Mubadala Capital-backed Aquarian Holdings is in advanced talks to take US life insurer Brighthouse Financial private in a $4bn transaction that could be announced as soon as this weekend, according to three people briefed on the matter.

    Aquarian will pay as much as $70 per share, a 40 per cent premium to Brighthouse’s equity price in January when the Financial Times reported the beginning of the sale process. Brighthouse shares closed on Thursday at $45.69.

    While talks have reached an advanced stage after months of on and off negotiations, the sources cautioned that no deal had been fully agreed and talks could ultimately break down.

    Aquarian is a New York-based asset manager run by Rudy Sahay, a former executive at Guggenheim Partners, and one of the pioneers in matching insurance assets with private investments such as securitised debt, leveraged loans and property.

    The Brighthouse auction also featured interest from several private capital groups, including Apollo, TPG, Sixth Street and Carlyle, but some potential bidders baulked during their due diligence process or were unwilling to pay a premium price.

    Advisers for Brighthouse including Goldman Sachs spent weeks vetting Aquarian’s financial firepower after the asset manager offered a deal price far greater than what rivals were willing to bid.

    Mubadala Capital, the Abu Dhabi-based private capital group, would lead equity financing for the deal, while a consortium of banks would also arrange a more than $1bn debt package, said the sources.

    Mubadala Capital is a minority investor in Aquarian after committing $1.5bn to the insurance-focused investment group last year.

    The Brighthouse sale process comes as several other large life insurance platforms, including American Equity Life, American National, Global Atlantic and Talcott Resolution, have merged into alternative asset managers.

    Insurers affiliated with private capital firms more aggressively invest customer funds in private debt, which can earn asset managers excess returns above payouts to policyholders, rather than in public investment-grade bonds.

    Brighthouse had struggled as an independent company since being spun off from MetLife in 2017. The group’s focus on variable annuities, a complex product that is expensive to hedge and carries high capital charges, has weighed on its results in recent years and led to quarterly losses because of large accounting swings.

    However, Brighthouse has a portfolio of $120bn in assets that Aquarian is expected to redeploy more heavily in private credit and other alternative investments.

    The deal would place Aquarian among the world’s largest private capital-backed life insurance groups. With about $25bn in assets, its acquisition of Brighthouse would increase its portfolio by about fourfold.

    Brighthouse, Aquarian and Mubadala Capital declined to comment.

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  • precision DNA repair may hold clues for human aging

    precision DNA repair may hold clues for human aging

    The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven by a unique protein, CIRBP. Scientists found that this mechanism not only preserves the whale’s genome but can also…

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  • IMF assured of Rs200b tax measures

    IMF assured of Rs200b tax measures

    Revenue steps will be taken if FBR misses Dec target or expenses rise above limits


    ISLAMABAD:

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  • Ceasefire at last: Pakistan and Afghanistan agree to truce after Istanbul peace talks; follow-up meeting set for Nov 6

    Ceasefire at last: Pakistan and Afghanistan agree to truce after Istanbul peace talks; follow-up meeting set for Nov 6

    Pakistan and Afghanistan finally agreed on Thursday to uphold a ceasefire during peace talks in Istanbul, according to Turkey, after the earlier discussions between the two sides had collapsed. The two countries had faced their most serious…

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  • Steadfast Shares Plunge as CEO Stands Aside Amid Investigation

    Steadfast Shares Plunge as CEO Stands Aside Amid Investigation

    Shares of Steadfast Group Ltd. dropped the most on record after the Australian insurance broker said its chief executive officer will take temporary leave amid an investigation of a workplace complaint made against him.

    The stock tumbled 19% on Friday after Robert Kelly chose to stand aside to enable an external probe into the allegations, according to an exchange statementBloomberg Terminal. No claims against him have been substantiated so far, the company said, without giving details about the complaint.

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