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  • Single-Cell and TCR Sequencing Reveal T Cell Biomarker in Tumor-Bearing Mice – Genetic Engineering and Biotechnology News

    1. Single-Cell and TCR Sequencing Reveal T Cell Biomarker in Tumor-Bearing Mice  Genetic Engineering and Biotechnology News
    2. A pan-immunotherapy signature to predict intratumoral CD8+ T cell expansions | Nature Communications  Nature
    3. Researchers…

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  • 16 Wardrobing Brands to Complete Your Closet, Top to Bottom

    16 Wardrobing Brands to Complete Your Closet, Top to Bottom

    Some brands don’t just produce and sell clothes—they offer a blueprint for getting dressed. These are the labels that make building a wardrobe effortless, where you’ll discover everything from crisp shirting and tailored trousers, to…

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  • ‘The Long Walk’ To ‘IT’

    ‘The Long Walk’ To ‘IT’

    Author Stephen King’s prodigious body of published works has spawned many a film or television show adaptation. King’s works have especially fueled Hollywood and the box office this year alone with three films and a TV…

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  • Soil sample offers clues on lunar water evolution

    Soil sample offers clues on lunar water evolution

    Chinese scientists studying a 2-gram lunar soil sample from the Chang”e 6 mission have identified rare CI chondrite impact residues, providing new insights into mass transfer in the inner solar system and offering new…

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  • Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adults

    Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adults

    Researchers found that daily freeze-dried strawberry intake enhanced antioxidant biomarkers, lowered inflammation, and improved fasting glucose, suggesting a delicious way to support metabolic health and prevent diabetes…

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  • Canon’s RF/EF lens production exceeds 170 million units, extending its world record in interchangeable lens production

    Canon’s RF/EF lens production exceeds 170 million units, extending its world record in interchangeable lens production

    Canon’s RF/EF lens production exceeds 170 million units, extending its world record in interchangeable lens production

    TOKYO, October 22, 2025—Canon Inc. announced today that, in October 2025, Canon reached a historic milestone of producing a cumulative total of 170 million RF and EF interchangeable lenses for its EOS series, extending its world record1 for the highest number of interchangeable camera lenses ever produced.

    A logo commemorating Canon’s achievement
    The RF70-200mm F2.8 L IS USM Z, the 170 millionth lens produced
    The RF70-200mm F2.8 L IS USM Z (released in November 2024),
    the 170 millionth lens produced

    The EF lens was introduced in 1987 as the dedicated lens system for Canon’s EOS autofocus single-lens reflex film camera, debuting simultaneously with the EOS system itself. Since their inception, EF lenses have led the industry by incorporating a series of world-first2 technologies, including the Ultrasonic Motor (USM), Image Stabilizer (IS) technology, and a multilayered Diffractive Optical (DO) element, and have undergone numerous evolutions.

    In 2018, Canon launched the RF lens series, designed for the EOS R mirrorless camera system, which features a large aperture, short back focus, and high-speed communication system to deliver even higher image quality. The RF and EF lens series lineup now includes a total of 108 models3, covering a wide range of focal lengths4 from ultra-wide 10mm to super-telephoto 1200mm. The series also includes the world’s first VR lens5, lenses with built-in power zoom suited for video shooting, and even those compatible with power zoom adapters—expanding the scope of creative expression and meeting the diverse needs of users for both still photography and video.

    EF lens production began at Canon’s Utsunomiya Plant in 1987. Since then, both EF and RF lenses have gained strong support from a wide range of users—from beginners to professionals—leading to steady growth in production volume. Today, Canon manufactures lenses at five sites: Utsunomiya Plant; Canon Inc., Taiwan; Canon Opto (Malaysia) Sdn. Bhd.; Oita Canon Inc.; and Miyazaki Canon Inc. Milestones include 10 million units produced by 1995 and 50 million by 2009. Then in 2014, Canon became the first company in the world to reach 100 million interchangeable camera lenses produced. In October 2025, the company reached 170 million units, leading to the achievement of this world record. The 170 millionth lens produced was the RF70-200mm F2.8 L IS USM Z.

    Canon has maintained the No.16 global market share for digital interchangeable-lens cameras for 22 consecutive years since 2003. Moving forward, Canon will continue to refine its proprietary imaging technologies and further strengthen and expand its lens lineup, pioneering new imaging possibilities and contributing to the continued evolution of photographic and video culture.

    • 1

      Includes EF, EF-S, EF-M, EF Cinema, RF, RF-S, and RF Cinema lenses and extenders. As of October 21, 2025 (according to a survey by Canon)

    • 2

      Among SLR cameras (according to a survey by Canon)

    • 3

      Number of products sold as of October 22, 2025 (including extenders). The number of lens models for sale is different according to
      market figures.

    • 4

      Focal length is 5.2mm to 1200mm when including VR lenses

    • 5

      An interchangeable digital camera lens that enables VR footage with a single camera. Among interchangeable lens digital cameras released as of October 5, 2021 (according to a survey by Canon)

    • 6

      Refers to unit share (according to a survey by Canon)

    Highlights in the development of the RF/EF Lens Series

    EF75-300mm f/4-5.6 IS USM
    EF75-300mm f/4-5.6 IS USM
    (September 1995)
    EF400mm f/4 DO IS USM
    EF400mm f/4 DO IS USM
    (December 2001)
    EF24mm f/1.4L II USM
    EF24mm f/1.4L II USM
    (December 2008)

    The EF lens, which was introduced alongside EOS in March 1987, has adopted a variety of world-first technologies, including Image Stabilizer (IS) technology, featured in the EF75-300mm f/4-5.6 IS USM released in 1995; a multilayered Diffractive Optical (DO) element, used in the EF400mm f/4 DO IS USM launched in 2001; and Subwavelength Structure Coating (SWC)7, applied to the EF24mm f/1.4L II USM released in 2008.

    EOS VR SYSTEM RF5.2mm F2.8 L DUAL FISHEYE
    EOS VR SYSTEM RF5.2mm F2.8 L DUAL FISHEYE
    (December 2021)
    RF24-105mm F2.8 L IS USM Z
    RF24-105mm F2.8 L IS USM Z
    *shown with power zoom adapter
    (December 2023)
    RF85mm F1.4 L VCM
    RF85mm F1.4 L VCM
    (September 2025)

    In 2021, Canon launched the EOS VR System, a VR video system consisting of a mirrorless camera8, dedicated lens, and PC software, thereby creating a 3D 180° VR video through an interchangeable lens camera. In 2024, Canon began rolling out a new series of hybrid lenses equipped with iris rings, designed to meet the needs of both still photography and professional video production. For zoom lenses, the company has also launched RF24-105mm F2.8 L IS USM Z and RF70-200mm F2.8 L IS USM Z which are compatible with power zoom adapters. For single focus lenses, the company released F1.4 L hybrid prime lens series that unified the size and ring and button position across models. In September 2025, Canon launched RF85mm F1.4 L VCM, the fifth model in this series, demonstrating that it can meet demands in line with the changing times.

    • 7

      A special coating with advanced anti-reflective properties

    • 8

      For applicable cameras, please visit the official Canon website.

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  • Reba McEntire reflects on ‘precious’ bond with late stepson Brandon Blackstock

    Reba McEntire reflects on ‘precious’ bond with late stepson Brandon Blackstock

    Reba McEntire recalls heartwarming memories with late stepson Brandon Blackstock

    Reba McEntire is reflecting on her precious relationship with her late stepson, Brandon Blackstock.

    The 70-year-old actress, who was…

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  • Elizabeth Olsen On Only Acting In Movies With Theatrical Release & Why She’d “Jump” At Chance To Play Wanda In MCU Again

    Elizabeth Olsen On Only Acting In Movies With Theatrical Release & Why She’d “Jump” At Chance To Play Wanda In MCU Again

    Elizabeth Olsen is sharing her passion for moviemaking and, in a recent interview, explained why seeing films in a theater is essential.

    The actress recently mentioned that she would rather star in films that get theatrical…

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  • LME Week takeaways: Metals find their footing | articles

    LME Week takeaways: Metals find their footing | articles

    Gold drew attention during LME Week, with prices up by around 60% this year. The rally has been driven by uncertainties over global trade, heightened geopolitical tensions, US fiscal stability and the Fed’s independence. The start of the Fed’s easing cycle also boosted gold, which doesn’t pay any interest. The rally has been driven by physical buying, with central banks and private investors accumulating gold at record volumes.

    But after a weeks-long rally that saw the precious metal hitting successive record highs, gold slid the most in 12 years this week. This signalled that some momentum might have been stretched. Gold was dragged down by a combination of factors, including profit-taking across precious metals, easing seasonal demand from Diwali, positive trade talks between China and the US, uncertainty over investor positions amid the US government shutdown, and a stronger dollar. The pullback underscores the risk that the rally might have moved ahead of underlying fundamentals.

    But despite this sharp pullback, gold’s outlook remains constructive, underpinned by macro uncertainty and diversification demand.

    The shift in central banks’ purchases has been structural, with the pace of buying doubling in 2022 following Russia’s invasion of Ukraine. Central banks’ appetite for gold is driven by concerns from countries about Russian-style sanctions on their foreign assets, as well as shifting strategies on currency reserves. The top year-to-date buyer has been the National Bank of Poland, and it just announced it aims to increase its reserves from 21% to 30%.

    ETFs have been another powerful force behind gold’s record-breaking rally this year, with holdings surging in recent weeks. In fact, gold ETFs have added as much gold in September alone as central banks did during the first quarter of this year combined, according to the World Gold Council. With ETF holdings still shy of a peak hit in 2022, there could be room for further increases.

    The downside should be limited, supported by geopolitical concerns, sustained central bank demand and expectations of further monetary easing, although near-term volatility may persist. For now, gold’s pullback looks like a healthy correction within a still-positive trend.

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  • Gold (XAU/USD) and Silver Prices Stabilize After Massive Drops

    Gold (XAU/USD) and Silver Prices Stabilize After Massive Drops

    Gold and silver wavered, after suffering their steepest selloffs in years on Tuesday as concern their dizzying rallies in recent weeks had left them overvalued.

    Spot gold traded near $4,140 an ounce after tumbling as much as 6.3% in the previous session, the biggest intraday drop in more than a dozen years. Silver edged higher after being down 8.7% at one point on Tuesday. The slumps came after technical indicators showed scorching rallies for both metals were likely overstretched.

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