While the U.S. Centers for Disease Control and Prevention (CDC) states that Dengue is a year-round risk in many parts of the world, some countries are reporting an increase in cases of this mosquito-borne disease this year.
Since the beginning of 2025, over 4 million Dengue cases and over 2,500 dengue-related deaths have been reported from 101 countries/territories.
On August 21, 2025, the CDC updated its Travel Health Advisory, identifying a higher-than-expected number of dengue cases among U.S. travelers returning from these 18 countries.
Should you visit these areas, the CDC says to prevent mosquito bites, use an EPA-registered insect repellent, wear long-sleeved shirts and long pants when outdoors, and sleep in an air-conditioned room or a room with window screens.
The disease can take up to two weeks to develop, with illness generally lasting less than a week. Symptoms of Dengue include fever, headache, nausea, vomiting, rash, muscle and joint pain, and minor bleeding.
Currently, U.S. FDA-approved Dengue vaccines are only available in Puerto Rico, where Dengue has become endemic.
The second-generation vaccination is available in various countries, but not in the USA.