The authors acknowledge the participants, data custodians, and investigators of the Australian Cardiovascular disease Data Commons (ACDC). The ACDC is funded by the Medical Research Future Fund (RFRHPI000110 and MRFCRI000210). The authors are supported by National Health and Medical Research Council of Australia Emerging Leadership and L3 Investigator Grants (2023/GNT2027256 and 2021/GNT2009965).