Target ID & Validation in Novel Immune Cells using CRISPR Screening
This poster demonstrates the use CRISPR screening in primary human immune cells to identify and validate novel targets in the therapeutic areas of autoimmune & inflammation and immuno-oncology.
Key highlights of the poster include:
- details of the CRISPR screening methods in specific immune cells
- the presentation of a case study based on a CRISPR/Cas9 screening platform in primary human T cells used to identify novel Treg modulating targets
- information on the functional assays used to validate the relevance of the target in the cell type of interest