Our data, coupled with clinical observations in TDD, do not support a primary role for TANGO2 as a heme chaperone. In C. elegans lacking TANGO2 homologs, we were unable to fully replicate prior findings of defective heme transport using…
Cross-species evaluation of TANGO2 homologs, including HRG-9 and HRG-10 in Caenorhabditis elegans, challenges a proposed role in heme trafficking
