Sex modifies the association between malnutrition and chronic kidney disease in community-dwelling older adults in the United States | BMC Geriatrics

  • Merchant RA, Vathsala A. Healthy aging and chronic kidney disease. Kidney Res Clin Pract. 2022;41(6):644–56. https://doi.org/10.23876/j.krcp.22.112.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Foreman KJ, Marquez N, Dolgert A, Fukutaki K, Fullman N, McGaughey M, et al. Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016–40 for 195 countries and territories. Lancet (London, England). 2018;392(10159):2052–90. https://doi.org/10.1016/s0140-6736(18)31694-5.

    Article 
    PubMed 

    Google Scholar 

  • Wang XH, Mitch WE. Mechanisms of muscle wasting in chronic kidney disease. Nat Rev Nephrol. 2014;10(9):504–16. https://doi.org/10.1038/nrneph.2014.112.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Freeman AM, Morris PB, Barnard N, Esselstyn CB, Ros E, Agatston A, et al. Trending cardiovascular nutrition controversies. J Am Coll Cardiol. 2017;69(9):1172–87. https://doi.org/10.1016/j.jacc.2016.10.086.

    Article 
    PubMed 

    Google Scholar 

  • Yang Q, Ni S. Prognostic value of malnutrition using geriatric nutritional risk index in patients with coronary chronic total occlusion after percutaneous coronary intervention. Clin Nutr (Edinburgh, Scotland). 2021;40(7):4537. https://doi.org/10.1016/j.clnu.2021.05.023.

    Article 
    CAS 

    Google Scholar 

  • Shangguan X, Xiong J, Shi S, Liao Y, Chen L, Deng J, et al. Impact of the malnutrition on mortality in patients with osteoporosis: a cohort study from NHANES 2005–2010. Front Nutr. 2022;9: 868166. https://doi.org/10.3389/fnut.2022.868166.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Raposeiras Roubín S, Abu Assi E, Cespón Fernandez M, Barreiro Pardal C, Lizancos Castro A, Parada JA, et al. Prevalence and prognostic significance of malnutrition in patients with acute coronary syndrome. J Am Coll Cardiol. 2020;76(7):828–40. https://doi.org/10.1016/j.jacc.2020.06.058.

    Article 
    PubMed 

    Google Scholar 

  • Dent E, Hoogendijk EO, Visvanathan R, Wright ORL. Malnutrition screening and assessment in hospitalised older people: a review. J Nutr Health Aging. 2019;23(5):431–41. https://doi.org/10.1007/s12603-019-1176-z.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Xu Y, Yan Z, Li K, Liu L, Xu L. Association between nutrition-related indicators with the risk of chronic obstructive pulmonary disease and all-cause mortality in the elderly population: evidence from NHANES. Front Nutr. 2024;11: 1380791. https://doi.org/10.3389/fnut.2024.1380791.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Li L, Wu M, Yu Z, Niu T. Nutritional status indices and monoclonal gammopathy of undetermined significance risk in the elderly population: findings from the National Health and Nutrition Examination Survey. Nutrients. 2023. https://doi.org/10.3390/nu15194210.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Pan D, Guo J, Su Z, Wang J, Wu S, Guo J, et al. Association of the controlling nutritional status score with all-cause mortality and cancer mortality risk in patients with type 2 diabetes: NHANES 1999–2018. Diabetol Metab Syndr. 2023;15(1):175. https://doi.org/10.1186/s13098-023-01138-2.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Dai L, Mukai H, Lindholm B, Heimbürger O, Barany P, Stenvinkel P, et al. Clinical global assessment of nutritional status as predictor of mortality in chronic kidney disease patients. PLoS One. 2017;12(12):e0186659. https://doi.org/10.1371/journal.pone.0186659.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Guligowska A, Corsonello A, Pigłowska M, Roller-Wirnsberger R, Wirnsberger G, Ärnlöv J, et al. Association between kidney function, nutritional status and anthropometric measures in older people: the screening for CKD among older people across Europe (SCOPE) study. BMC Geriatr. 2020;20(Suppl 1): 366. https://doi.org/10.1186/s12877-020-01699-1.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • de Ignacio Ulíbarri J, González-Madroño A, de Villar NG, González P, González B, Mancha A, et al. CONUT: a tool for controlling nutritional status. First validation in a hospital population. Nutr Hosp. 2005;20(1):38–45.

    Google Scholar 

  • Zhang R, Wang Y, Liao L, Liao Y, Fang Y, Shen Y. The relationship between C-reactive protein/albumin ratio and mortality in hypertensive patients: a national cohort study. Nutr Metab Cardiovasc Dis. 2024;34(7):1601–9. https://doi.org/10.1016/j.numecd.2024.02.011.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Zhang Y, Moran AE. Trends in the prevalence, awareness, treatment, and control of hypertension among young adults in the United States, 1999 to 2014. Hypertension. 2017;70(4):736–42. https://doi.org/10.1161/hypertensionaha.117.09801.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases. Kidney international. 2021;100(4s):S1-S276. https://doi.org/10.1016/j.kint.2021.05.021.

  • Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF 3rd, Feldman HI, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150(9):604–12. https://doi.org/10.7326/0003-4819-150-9-200905050-00006.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Qin Z, Li H, Wang L, Geng J, Yang Q, Su B, et al. Systemic immune-inflammation index is associated with increased urinary albumin excretion: a population-based study. Front Immunol. 2022;13:863640. https://doi.org/10.3389/fimmu.2022.863640.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Becker PJ, Nieman Carney L, Corkins MR, Monczka J, Smith E, Smith SE, et al. Consensus statement of the Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition: indicators recommended for the identification and documentation of pediatric malnutrition (undernutrition). J Acad Nutr Diet. 2014;114(12):1988–2000. https://doi.org/10.1016/j.jand.2014.08.026.

    Article 
    PubMed 

    Google Scholar 

  • Couser WG, Remuzzi G, Mendis S, Tonelli M. The contribution of chronic kidney disease to the global burden of major noncommunicable diseases. Kidney Int. 2011;80(12):1258–70. https://doi.org/10.1038/ki.2011.368.

    Article 
    PubMed 

    Google Scholar 

  • Bello AK, Levin A, Tonelli M, Okpechi IG, Feehally J, Harris D, et al. Assessment of global kidney health care status. JAMA. 2017;317(18):1864–81. https://doi.org/10.1001/jama.2017.4046.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Rey-García J, Donat-Vargas C, Sandoval-Insausti H, Bayan-Bravo A, Moreno-Franco B, Banegas JR, et al. Ultra-processed food consumption is associated with renal function decline in older adults: a prospective cohort study. Nutrients. 2021. https://doi.org/10.3390/nu13020428.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kalantar-Zadeh K, Fouque D. Nutritional management of chronic kidney disease. N Engl J Med. 2017;377(18):1765–76. https://doi.org/10.1056/NEJMra1700312.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Chen L, Huang Z, Li W, He Y, Liang J, Lu J, et al. Malnutrition and the risk for contrast-induced acute kidney injury in patients with coronary artery disease. Int Urol Nephrol. 2022;54(2):429–35. https://doi.org/10.1007/s11255-021-02915-6.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Otaki Y, Watanabe T, Shimizu M, Tachibana S, Sato J, Kobayashi Y, et al. Association of malnutrition with renal dysfunction and clinical outcome in patients with heart failure. Sci Rep. 2022;12(1):16673. https://doi.org/10.1038/s41598-022-20985-z.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Qu W, Liu S, Gu J, Wei X. Association between controlling nutritional status score and chronic kidney disease in diabetic patients: a cross-sectional study based on the National Health and Nutrition Examination Survey. Int Urol Nephrol. 2024;56(2):795–804. https://doi.org/10.1007/s11255-023-03740-9.

    Article 
    PubMed 

    Google Scholar 

  • Shi Y, Yu C, Zhou W, Wang T, Zhu L, Cheng X, et al. The association of malnutrition with chronic kidney disease in the older chinese population with hypertension: evidence from the china h-type hypertension registry study. J Renal Nutr. 2023.https://doi.org/10.1053/j.jrn.2023.04.005.

  • Sun B, Zhao Y, Lu W, Chen Y. The relationship of malnutrition with cognitive function in the older Chinese population: evidence from the Chinese Longitudinal Healthy Longevity Survey Study. Front Aging Neurosci. 2021;13:766159. https://doi.org/10.3389/fnagi.2021.766159.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Nakagawa N, Maruyama K, Hasebe N. Utility of geriatric nutritional risk index in patients with chronic kidney disease: a mini-review. Nutrients. 2021;13(11).https://doi.org/10.3390/nu13113688.

  • Lin TY, Hung SC. Geriatric nutritional risk index is associated with unique health conditions and clinical outcomes in chronic kidney disease patients. Nutrients. 2019. https://doi.org/10.3390/nu11112769.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Panichi V, Cupisti A, Rosati A, Di Giorgio A, Scatena A, Menconi O, et al. Geriatric nutritional risk index is a strong predictor of mortality in hemodialysis patients: data from the Riscavid cohort. J Nephrol. 2014;27(2):193–201. https://doi.org/10.1007/s40620-013-0033-0.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Xiong J, Wang M, Zhang Y, Nie L, He T, Wang Y, et al. Association of geriatric nutritional risk index with mortality in hemodialysis patients: a meta-analysis of cohort studies. Kidney Blood Press Res. 2018;43(6):1878–89. https://doi.org/10.1159/000495999.

    Article 
    PubMed 

    Google Scholar 

  • Zou P, Zhang Y, Chen L, Liu M, Nie H, Gao H, et al. Associations between the geriatric nutritional risk index and the risk of and mortality associated with chronic kidney disease in older individuals. BMC Public Health. 2024;24(1):2893. https://doi.org/10.1186/s12889-024-20283-5.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Rossi AP, Scalfi L, Abete P, Bellelli G, Bo M, Cherubini A, et al. Controlling nutritional status score and geriatric nutritional risk index as a predictor of mortality and hospitalization risk in hospitalized older adults. Nutrition. 2025;131:112627. https://doi.org/10.1016/j.nut.2024.112627.

    Article 
    PubMed 

    Google Scholar 

  • Peng SM, Ren JJ, Yu N, Xu JY, Chen GC, Li X, et al. The prognostic value of the Naples prognostic score for patients with non-small-cell lung cancer. Sci Rep. 2022;12(1): 5782. https://doi.org/10.1038/s41598-022-09888-1.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Liang J, Zhang L, Huang Z, He Y, Ling Y, Chen K, et al. Implications of malnutrition on contrast-associated acute kidney injury in young and old patients undergoing percutaneous coronary intervention: a multicenter prospective cohort. Front Nutr. 2021;8:795068. https://doi.org/10.3389/fnut.2021.795068.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Quinlan GJ, Martin GS, Evans TW. Albumin: biochemical properties and therapeutic potential. Hepatology (Baltimore, MD). 2005;41(6):1211–9. https://doi.org/10.1002/hep.20720.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Wiedermann CJ, Joannidis M. Nephroprotective potential of human albumin infusion: a narrative review. Gastroenterol Res Pract. 2015;2015:912839. https://doi.org/10.1155/2015/912839.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Roche M, Rondeau P, Singh NR, Tarnus E, Bourdon E. The antioxidant properties of serum albumin. FEBS Lett. 2008;582(13):1783–7. https://doi.org/10.1016/j.febslet.2008.04.057.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Ratliff BB, Abdulmahdi W, Pawar R, Wolin MS. Oxidant mechanisms in renal injury and disease. Antioxid Redox Signal. 2016;25(3):119–46. https://doi.org/10.1089/ars.2016.6665.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Tonelli M, Sacks F, Pfeffer M, Jhangri GS, Curhan G. Biomarkers of inflammation and progression of chronic kidney disease. Kidney Int. 2005;68(1):237–45. https://doi.org/10.1111/j.1523-1755.2005.00398.x.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Yang Y, Zhou H, Zhang P, Chao W, Zou Y, Yang M. Evaluation of objective nutritional indexes as predictors of worse outcomes in peritoneal dialysis patients. Nutrition (Burbank, Los Angeles County, Calif). 2020; 110963. https://doi.org/10.1016/j.nut.2020.110963.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Omran ML, Morley JE. Assessment of protein energy malnutrition in older persons, part II: laboratory evaluation. Nutrition (Burbank, Los Angeles County, Calif). 2000;16(2):131–40. https://doi.org/10.1016/s0899-9007(99)00251-8.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Scheen AJ. Cardiovascular effects of gliptins. Nat Rev Cardiol. 2013;10(2):73–84. https://doi.org/10.1038/nrcardio.2012.183.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Ferro CJ, Mark PB, Kanbay M, Sarafidis P, Heine GH, Rossignol P, et al. Lipid management in patients with chronic kidney disease. Nat Rev Nephrol. 2018;14(12):727–49. https://doi.org/10.1038/s41581-018-0072-9.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Zhao W, An Z, Hong Y, Zhou G, Guo J, Zhang Y, et al. Low total cholesterol level is the independent predictor of poor outcomes in patients with acute ischemic stroke: a hospital-based prospective study. BMC Neurol. 2016;16:36. https://doi.org/10.1186/s12883-016-0561-z.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Chesnaye NC, Carrero JJ, Hecking M, Jager KJ. Differences in the epidemiology, management and outcomes of kidney disease in men and women. Nat Rev Nephrol. 2024;20(1):7–20. https://doi.org/10.1038/s41581-023-00784-z.

    Article 
    PubMed 

    Google Scholar 

  • Carrero JJ, Hecking M, Chesnaye NC, Jager KJ. Sex and gender disparities in the epidemiology and outcomes of chronic kidney disease. Nat Rev Nephrol. 2018;14(3):151–64. https://doi.org/10.1038/nrneph.2017.181.

    Article 
    PubMed 

    Google Scholar 

  • Matsuda T, Yamamoto T, Muraguchi A, Saatcioglu F. Cross-talk between transforming growth factor-beta and estrogen receptor signaling through Smad3. J Biol Chem. 2001;276(46):42908–14. https://doi.org/10.1074/jbc.M105316200.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Ji H, Zheng W, Menini S, Pesce C, Kim J, Wu X, et al. Female protection in progressive renal disease is associated with estradiol attenuation of superoxide production. Gend Med. 2007;4(1):56–71. https://doi.org/10.1016/s1550-8579(07)80009-x.

    Article 
    PubMed 

    Google Scholar 

  • Stumpf F, Keller B, Gressies C, Schuetz P. Inflammation and nutrition: friend or foe? Nutrients. 2023. https://doi.org/10.3390/nu15051159.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Ranich T, Bhathena SJ, Velasquez MT. Protective effects of dietary phytoestrogens in chronic renal disease. J Renal Nutr. 2001;11(4):183–93.

    CAS 

    Google Scholar 

  • Moxley G, Stern AG, Carlson P, Estrada E, Han J, Benson LL. Premenopausal sexual dimorphism in lipopolysaccharide-stimulated production and secretion of tumor necrosis factor. J Rheumatol. 2004;31(4):686–94.

    CAS 
    PubMed 

    Google Scholar 

  • Baumgartner RN, Koehler KM, Gallagher D, Romero L, Heymsfield SB, Ross RR, et al. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol. 1998;147(8):755–63. https://doi.org/10.1093/oxfordjournals.aje.a009520.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16–31. https://doi.org/10.1093/ageing/afy169.

    Article 
    PubMed 

    Google Scholar 

  • Kelly DM, Jones TH. Testosterone and obesity. Obes Rev. 2015;16(7):581–606. https://doi.org/10.1111/obr.12282.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Jawad A, Reed E, Severi K, Jenner K, Reed H, Cheeseman H. Development of a framework for action to advocate for a coherent prevention policy for tobacco, alcohol, and foods high in fats, salt, or sugar: a mixed-methods approach. Lancet (London, England). 2023;402(Suppl 1):S57. https://doi.org/10.1016/s0140-6736(23)02109-8.

    Article 
    PubMed 

    Google Scholar 

  • Berube L, Duffy VB, Hayes JE, Hoffman HJ, Rawal S. Associations between chronic cigarette smoking and taste function: results from the 2013–2014 national health and nutrition examination survey. Physiol Behav. 2021;240: 113554. https://doi.org/10.1016/j.physbeh.2021.113554.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kovesdy CP, Kopple JD, Kalantar-Zadeh K. Management of protein-energy wasting in non-dialysis-dependent chronic kidney disease: reconciling low protein intake with nutritional therapy. Am J Clin Nutr. 2013;97(6):1163–77. https://doi.org/10.3945/ajcn.112.036418.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Ikizler TA. Nutrition, inflammation and chronic kidney disease. Curr Opin Nephrol Hypertens. 2008;17(2):162–7. https://doi.org/10.1097/MNH.0b013e3282f5dbce.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Shi Y, Yu C, Zhou W, Wang T, Zhu L, Cheng X, et al. The association of malnutrition with chronic kidney disease in the older chinese population with hypertension: evidence from the China H-type hypertension registry study. J Renal Nutr. 2024;34(3):209–15. https://doi.org/10.1053/j.jrn.2023.04.005.

    Article 

    Google Scholar 

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