N-glycosylation blockers reduce SARS-CoV-2 infection

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses the spike antigens on its surface to mediate host cell attachment and entry. A new Virology journal study shows that the N-glycosylation pattern of SARS-CoV-2 is crucial to normal spike activity, such that its in vitro activity is reduced by using molecules that inhibit the synthesis or attachment of spike…

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News Source: https://www.news-medical.net/news/20220220/N-glycosylation-blockers-reduce-SARS-CoV-2-infection.aspx

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