It will be an almighty challenge, given what Djokovic has produced on the lawns so far this fortnight.
He overwhelmed fellow Serbian Miomir Kecmanovic 6-3 6-0 6-4 on Centre Court on Saturday – his 100th match victory at Wimbledon.
The more the 38-year-old wins, the more history he creates, and there are extraordinary milestones on the line for him at SW19 this year, where he is targeting a seventh consecutive final.
A tournament victory would see him equal Roger Federer’s men’s record of eight singles titles, earn an all-time record 25th major title, and become the oldest Grand Slam singles champion in Open-era history.
Despite overlapping for many years on tour, Djokovic and De Mianur have only played three times. Djokovic leads the head-to-head 2-1, and in their only Grand Slam meeting, Djokovic dropped just five games in a Rod Laver Arena masterclass in 2023.
He is, however, wary of how this match-up could unfold on grass.
“It’s gonna be a great challenge,” Djokovic told Stan Sport.
“I think Alex is a player who has been improving so much [in the] last couple of years. He’s already now an established top-10 player, and on grass particularly I think it suits him very well.