The WHO today published its Multi-country outbreak of mpox External situation report #57.
The World Health Organization (WHO) stated on August 28, 2025, that all monkeypox virus (MPXV) clades continue to circulate in several countries. When mpox outbreaks are not rapidly contained and human-to-human transmission is not interrupted, they continue to pose a risk of sustained community transmission.
In July 2025, 47 countries in five (out of six) WHO regions reported a total of 3,924 confirmed cases, including 30 deaths (case fatality ratio 0.8%).
The South-East Asian and Western Pacific regions reported an increase in cases in July 2025, while the African Region, European Region, and the Region of the Americas reported a decrease.
To alert international travelers to this serious health risk, the WHO Director-General has extended the standing recommendations for mpox issued to States Parties until August 20, 2026, to prevent further spread or reduce the international spread of mpox, as well as its impact on health.
The WHO and the U.S. CDC recommend mpox vaccination for those with the highest risk profile.