After taking the software industry by storm, generative AI is now moving into a broad set of industries, including manufacturing, where it is helping manage unpredictability and support real-time decision-making. Gen AI’s ability to codify, automate, and distribute organizational expertise may eventually reshape work structures from the shop floor to the C-suite. Already some companies are using it to analyze the flood of information generated in factories and to predict problems, simulate complex scenarios, and optimize processes in real time. By working with a wide range of manufacturing industry data—from maintenance manuals and machine automation code to complex diagrams, 3D drawings, and process data—gen AI has the potential to establish new ways for people and machines to collaborate.