Author: admin

  • Third earthquake hits Afghanistan as death toll rises above 2,200 | Afghanistan

    Third earthquake hits Afghanistan as death toll rises above 2,200 | Afghanistan

    A magnitude 6.2 earthquake has shaken Afghanistan as the death toll from the devastating quake on Sunday rose to more than 2,200.

    It struck south-eastern regions on Thursday night, according to the Helmholtz Centre for Geosciences in Germany. It was not immediately clear how much damage there was.

    A 5.5 magnitude aftershock struck on Tuesday, causing panic and interrupting rescue efforts as more roads were cut off by rockfall.

    Hamdullah Fitrat, a Taliban spokesperson, confirmed on Thursday that the death toll from Sunday’s magnitude 6.0 earthquake had risen to 2,205 – up from previous estimates of 1,400 and making it one of the deadliest natural disasters to hit the country in decades.

    It hit the mountainous and remote eastern part of the country around midnight on Sunday, levelling entire villages where people were trapped under rubble.

    Most of the casualties were in Kunar province, where many houses are built from wood and mud bricks, making them highly vulnerable to earth tremors.

    Rescuers have managed to reach villages that had been completely cut off by the disaster and bodies continued to be pulled from debris on Thursday.

    About 98% of the buildings in Kunar were damaged or destroyed, according to an assessment from the charity, Islamic Relief.

    The rough and mountainous terrain has been hindering relief efforts. Taliban authorities have deployed helicopters and airdropped army commandos to help locate and rescue survivors. Aid workers reported walking for hours to reach villages cut off by landslides and rockfall.

    Resident Muhammad Israel said the quake unleashed a landslide that buried his home, livestock and belongings in Kunar.

    “All the rocks came down from the mountain,” he said. “I barely got my children out of there. The earthquake jolts are still happening. It is impossible to live there.”

    He was staying at a UN medical camp in Nurgal, one of the worst-affected areas. “The situation is also bad for us here, we don’t have shelter and are living under open skies,” he added.

    Rescue and relief efforts have been hampered by a lack of international aid funding and resources flowing into the country. Since the Taliban seized back power in 2021 and began imposing hardline religious laws, making it difficult for NGOs and aid groups to function, there has been a steep drop in support.

    Aid agencies said they were urgently in need of staff and supplies to tend to the injured and to house tens of thousands who have been left homeless and without access to food or water. About 84,000 people have been affected so far.

    The Norwegian Refugee Council said it had fewer than 450 staff in Afghanistan, whereas it had 1,100 in 2023 when the last major quake struck the country. The council has only one warehouse and no emergency stock.

    “We will need to purchase items once we get the funding but this will take potentially weeks and people are in need now,” said Maisam Shafiey, a communications and advocacy adviser for the council in Afghanistan.

    “We have only $100,000 [£75,000] available to support emergency response efforts. This leaves an immediate funding gap of $1.9m.”

    Shamshair Khan, a doctor tending to the injured at the UN camp in Nurgal, said supplies were already running out.

    “Neither these medicines are enough nor these services,” he said. “These people need more medicine and tents. They need food and clean drinking water. They need more aid. These people are in great pain.”

    The earthquakes came with Afghanistan already suffering from drought and a severe economic crisis. The withdrawal of USAid funding, after cuts by the Trump administration earlier this year, resulted in the closure of many hospitals and medical clinics.

    The pressures on the country have been exacerbated by the forced return of more than 2 million Afghans from neighbouring Pakistan and Iran, many of whom have nowhere to live or work.

    Continue Reading

  • Samsung Galaxy S26 dummies showcase updated design

    Samsung Galaxy S26 dummies showcase updated design

    While we’re several months away from their unveiling, the Galaxy S26 series has now leaked in a new image revealing their key design characteristics. The image is shared by Sonny Dickson, who holds a solid track record and showcases dummy molds for the three S26 members.

    From left to right, we have the Galaxy S26 Pro, Galaxy S26 Edge and Galaxy S26 Ultra. The S26 Edge stands out from the group thanks to its rectangular camera island. The look would be a big departure from the S25 Edge, which had a simple camera bump around the two lenses.

    If this is indeed the S26 Edge, then it would offer a design that’s expected to make its way to the iPhone 17 Pro and 17 Pro Max. As for the S26 Pro and S26 Ultra, we can see they will adapt the S25 Edge camera design with a trio of cameras stacked vertically into a more compact camera island.

    The new leak also suggests that Samsung will introduce its S26 series in February, just like it did with the Galaxy S25 series.

    Source

    Continue Reading

  • Chelsea strike verbal agreement with Angel City for Thompson – London Evening Standard

    Chelsea strike verbal agreement with Angel City for Thompson – London Evening Standard

    1. Chelsea strike verbal agreement with Angel City for Thompson  London Evening Standard
    2. Chelsea agree club record deal for USA forward Thompson  BBC
    3. Jenna’s Talking Points: Alyssa Thompson’s NWSL future in question, Current keep winning  Equalizer Soccer
    4. Chelsea Finalizes £1 Million Transfer for ACFC Star Alyssa Thompson as WSL Kicks Off  Just Women’s Sports
    5. Alyssa Thompson set to join Chelsea FC: What move for USWNT star means for NWSL  CBS Sports

    Continue Reading

  • Chess.com says 4,500 people had data stolen during June breach

    Chess.com says 4,500 people had data stolen during June breach

    The largest online platform for chess players said hackers gained access to customer information through a file transfer tool used by the company. 

    In breach notifications submitted to regulators in Maine and Vermont, Chess.com explained that 4,541 people had personal information exposed to hackers who breached an unnamed file transfer application between June 5 and June 18. 

    The incident was discovered by Chess.com on June 19 and federal law enforcement was immediately notified of the cyberattack. 

    A spokesperson for Chess.com would not say what information was stolen or which file transfer tool was breached. Two popular brands of file transfer tools — Wing FTP and CrushFTP — reported severe vulnerabilities in July that needed to be patched by customers. 

    “In June we became aware of unauthorized access to data stored in a third-party file transfer application used by Chess.com. Chess.com’s code was not compromised,” the spokesperson told Recorded Future News. 

    “We have determined that the unauthorized actor acquired certain Chess.com data for fewer than 0.003% of users. No banking information or member accounts, including usernames and passwords, were disclosed as a result of this incident.”

    Chess.com has existed since 2005 and is one of the world’s most popular platforms for playing chess — organizing 10 million games per day for more than 100 million registered users.  

    No hacking group has taken credit for the incident and Chess.com told victims that they “have no indication that any of your impacted data has been shared publicly on any online sources.”

    Get more insights with the

    Recorded Future

    Intelligence Cloud.

    Learn more.

    Continue Reading

  • Seriously, Acer’s new 16-inch featherweight laptop makes the MacBook Air seem heavy

    Seriously, Acer’s new 16-inch featherweight laptop makes the MacBook Air seem heavy

    Acer

    Follow ZDNET: Add us as a preferred source on Google.


    ZDNET’s key takeaways

    • Acer announced a slew of new laptops at IFA in Berlin, but the Swift Air 16 is one of the most exciting. 
    • The 16-inch laptop has a starting weight of 2.18 pounds – one of the lightest on the market. 
    • There are some trade-offs with getting a 16-inch laptop down to this size, specifically with battery life.

    Acer announced a new 16-inch featherweight laptop at IFA in Berlin yesterday, weighing just 2.18 pounds for the IPS configuration — about the same weight as Asus’ Zenbook A14, one of the lightest laptops I’ve ever held. The AMOLED weighs just 2.43 pounds, still lighter than a 13-inch MacBook Air. 

    The Acer Swift Air 16 manages this weight with a 16-inch display — an impressive feat on first glance and one of the lightest 16-inch laptops on the market right now. Currently, we have European pricing set at around €999, but no set price for North America just yet.

    Also: Finally, a 16-inch Windows laptop that I wouldn’t mind putting away my MacBook Pro for

    One of the first things to stick out with this laptop’s physical design is the keyboard, which looks a whole lot like the “zero-lattice” keyboard emblematic of Dell’s XPS lineup. The full-sized board on the Swift Air 16 features the same unified design with gapless keys (without the LED function panel, of course). It looks cool, but like the XPS, we’ll have to test its practicality.

    Acer Swift Air 16

    Acer

    The Swift Air 16 will come with an IPS or AMOLED option, up to a WQXGA+ resolution at 120Hz for the latter configuration at 400 nits of brightness. Under the hood, it’s powered by an AMD Ryzen AI 7 350 processor, officially earning it the Copilot+ PC title.

    It comes with 32GB of LPDDR5 memory and up to a 1TB M.2 PCIe Gen4 SSD, two USB-C ports, one USB-A, an HDMI 1.4 port, and an audio jack. 

    One thing to note is the device’s 50Wh battery, which is small for a 16-inch laptop. For comparison, the previously mentioned Zenbook A14 houses a 70Whr battery and weighs about the same, leading me to believe this is one of the more significant trade-offs made to get it down to weight. 

    Also: Is a refurbished MacBook viable in 2025? I did the math, and here’s my expert advice

    Acer says the Swift Air 16 will get up to 13 hours of battery life on one charge, which is average, but these days isn’t all that impressive for a thin and light Copilot+ PC. We’ll have to test how it performs in day-to-day use while untethered from power.

    The Swift Air 16 is geared toward hybrid commuters and professionals who want a device that can slip into a bag unnoticed and value portability and a nice-looking display over raw power. In that sense, it seems Acer is hoping the display, future-forward design, and lightness-at-all-costs outweigh (no pun intended) any gaps in longevity. 

    The Acer Swift Air 16 will be available in North America in Nov., 2025. 


    Continue Reading

  • RSV Vaccination Could Protect Older Adults From Hospitalization Across Multiple RSV Seasons

    RSV Vaccination Could Protect Older Adults From Hospitalization Across Multiple RSV Seasons

    One dose of a respiratory syncytial virus (RSV) vaccine could provide protection against RSV-associated hospitalization and severe infection for adults aged 60 years and older for 2 consecutive RSV seasons, according to findings from the IVY Network research group. The study authors, who published their findings in JAMA, noted that the results confirm the recommendation that older adults should receive an RSV vaccine while also providing a basis for determining how long a single dose of the vaccine remains effective.1,2

    “These results clearly demonstrate that the RSV vaccines prevent hospitalizations and critical illness due to RSV infection among older Americans,” Wesley Self, MD, MPH, principal investigator for the IVY Network and senior vice president for clinical research at Vanderbilt University Medical Center, said in a news release. “It is exciting to see the public health benefits of this new vaccination program.”2

    RSV Incidence and Vaccination Recommendations for Older Adults

    Peak RSV season occurs in the fall and winter, with an estimated 110,000 to 180,000 RSV-related hospitalizations among US adults aged 50 years and older, accounting for nearly 4000 to 8000 annual deaths. RSV symptoms are typically mild and cold-like, including a congested or runny nose, dry cough, low-grade fever, sore throat, sneezing, and headache. Symptoms of severe infection include fever, severe cough, wheezing, rapid breathing or difficulty breathing, and bluish skin color. RSV also could worsen conditions like asthma, chronic obstructive pulmonary disease, or heart failure, leading to hospitalization or fatal outcomes.3

    The CDC currently recommends a single dose of any of the 3 FDA-approved RSV vaccines—RSVPreF3 (Arexvy; GSK), RSVpreF (Abrysvo; Pfizer), or mRNA-1345 (mRESVIA; Moderna)—for all adults 75 years and older, along with individuals aged 60 to 74 years who are at increased risk of severe illness. Arexvy was the first RSV vaccine approved by the FDA in May 2023 for adults 60 years and older, followed by Abrysvo, also in May 2023, and mRESVIA in May 2024; however, their indications have been updated since their initial approval.4

    RSV Vaccine Effectiveness in Older Adults Across Seasons

    Researchers conducted a test-negative, case-controlled study, including a total of 6958 adults aged 60 years and older who were hospitalized for an acute respiratory illness during 2 RSV seasons: October 1, 2023, to March 31, 2024, and October 1, 2024, to April 30, 2025. Patients were included if they were tested for RSV, COVID-19, or influenza shortly after their illness began and their hospital admission. RSV was also systemically tested from nasal swabs at a central lab. The study authors noted that case patients were those who tested positive for RSV. Control patients were those who tested negative for RSV, COVID-19, and influenza. Patients with COVID-19 or influenza infections were not included in the control group. Using a multivariable logistic regression method, researchers compared the odds of being vaccinated against RSV between those who had RSV and those who did not.1,2

    Among the 6958 individuals, 821 have RSV and 6137 do not. The results demonstrated that RSV vaccination was 58% effective at preventing hospitalization over 2 seasons. However, when given in the same season, its effectiveness was higher at 69% compared to 48% when given in the previous season.1,2

    Further results found that the vaccine was less effective in individuals that were immunocompromised at 30%, compared to 67% among those who were not. It was also 56% effective in individuals with cardiovascular disease compared to 80% in those without.1,2

    “Our data show that the beneficial effects of RSV vaccines appear to wane over time,” Self said in the news release. “Redosing the vaccine at some interval after the initial dose could be a strategy to maintain protection over longer periods of time. It will be important to continue to closely monitor vaccine effectiveness over time to understand how long the benefit lasts after a single dose and if repeat dosing should be considered.”2

    REFERENCES
    1. Surie D, Self WH, Yuengling KA, et al. RSV Vaccine Effectiveness Against Hospitalization Among US Adults Aged 60 Years or Older During 2 Seasons. JAMA. Published online August 30, 2025. doi:10.1001/jama.2025.15896
    2. One shot of RSV vaccine effective against hospitalization in older adults for two seasons. EurekAlert! News Release. August 30, 2025. Accessed September 4, 2025. https://www.eurekalert.org/news-releases/1096473
    3. RSV in Adults. CDC. News release. Updated July 8, 2025. Accessed August 7, 2025. https://www.cdc.gov/rsv/adults/index.html
    4. RSV Vaccines. CDC. News release. August 30, 2024. Accessed April 17, 2025. https://www.cdc.gov/rsv/vaccines/index.html

    Continue Reading

  • New 3D eye model reveals causes of steroid-related glaucoma

    New 3D eye model reveals causes of steroid-related glaucoma

    The eye, like most organs, has an intricate plumbing system. Pressure builds when drainage is impaired, and this condition – glaucoma – can cause irreversible vision loss. Certain popular anti-inflammatory eye medications that contain steroids can in some cases compound the problem, although scientists have been at a loss to understand why.

    Now, Cornell researchers have identified the signaling mechanism that triggers steroid-induced glaucoma by creating a 3D “eye-on-a-chip” platform that mimics the flow of ocular fluids.

    The findings were published Aug. 27 in Nature Cardiovascular Research. The lead author is Renhao Lu, Ph.D. ’24.

    Steroid-induced glaucoma is a major clinical challenge. There’s no targeted therapy. We just say you are unlucky. There is a clear, unmet need to better understand, and prevent, this major side effect of the steroid in the clinics.”


    Esak (Isaac) Lee, senior author, assistant professor of biomedical engineering at Cornell Engineering

    Glaucoma is typically studied in animal models and simple 2D cell cultures, but those approaches often fail to capture the anatomical complexity and responsiveness of the human eye. 

    The solution from Lee’s lab, which studies lymphatic systems in different types of organs, has been to create 3D in-vitro models that can reproduce the systems’ layered structures while isolating biological and biophysical factors, all in a highly reproducible and controlled manner. Lee previously co-designed such a device that revealed a protein that jams up the necessary drainage in human skin lymphatic vessels, causing the painful swelling known as lymphedema.

    The eye’s lymphatic vessels are responsible for draining aqueous humor, a clear, water-like fluid that provides oxygen and nutrients but, when not removed, can cause intraocular pressure (IOP) to build, damaging neurons in the retina that are critical for transmitting light signals to the brain.

    Lee’s team realized the lymphatics in the eye, known as Schlemm’s canal (SC) cells, are quite different from those in the skin, lungs and other organs. These are surrounded by another cell type: trabecular meshwork (TM). Only with both cell layers working in conjunction can the lymphatic system flush the overproduced aqueous humor back into the bloodstream.

    The team built a 3D in-vitro device, known as a microphysiological system (MPS), with a double layer of TM and SC cells, with a curvature that mimicked the conduit structure of lymphatic vessels in the eye. The researchers treated the “eye-on-a-chip” with the anti-inflammatory steroid dexamethasone, which significantly impaired the drainage.

    This enabled the researchers to identify the culprit: A key receptor in TM cells, ALK5, responded to the steroid by downregulating a protein, vascular endothelial growth factor C (VEGFC), which normally loosens the endothelial junctions in SC cells, enabling fluid to pass through the endothelial wall. But that function was disrupted by ALK5/VEGFC signaling.

    “This communication causes the Schlemm’s canal junction abnormality,” Lee said. “The junctions become really thickened or tightened under the steroid, and that junction change increased the resistance of the outflow, causing this glaucoma.”

    The researchers confirmed the role of the mechanism in a mouse model. The finding opens up two paths to treating glaucoma: blocking ALK5 function; or providing additional VEGFC to the eye along with the steroid treatment.

    “We are now aiming to study other targets. There are some genes that people know are important for glaucoma, not just steroid-induced, and we could knock them out in these two cell types,” Lee said. “It’s complicated and difficult to target one cell type in conventional animal models, but in this system, we could do any genetic modification of these two cell types separately, and then combine them in the device to get a better understanding of these different mechanisms and different types of glaucoma.”

    Co-authors include postdoctoral researcher Anna Kolarzyk, Ph.D. ’25, and W. Daniel Stamer, professor of ophthalmology at Duke University.

    The researchers made use of the Cornell NanoScale Science and Technology Facility and was supported by the National Institutes of Health and the BrightFocus Foundation.

    Source:

    Journal reference:

    Lu, R., et al. (2025). Human ocular fluid outflow on-chip reveals trabecular meshwork-mediated Schlemm’s canal endothelial dysfunction in steroid-induced glaucoma. Nature Cardiovascular Research. doi.org/10.1038/s44161-025-00704-3

    Continue Reading

  • Join ADAO’s 20th Annual Asbestos Awareness & Prevention Event

    Join ADAO’s 20th Annual Asbestos Awareness & Prevention Event

    The Asbestos Disease Awareness Organization will host its 20th annual Asbestos Awareness and Prevention Conference on September 12 and 13 in New York City at the Westin Grand Central hotel. Global experts will discuss diagnosing, treating and preventing asbestos-related diseases like mesothelioma, as well as policy, advocacy and asbestos law. 

    Linda Reinstein, ADAO co-founder and president, tells us this conference is unique. Reinstein shares, “This conference is about using what we know, advancing what we should know and getting to a learned place so we can prevent asbestos exposure.”

    The event will start at 4:30 p.m. on Friday, September 12 with a candlelight vigil at the World Trade Center Memorial. Participants will honor those who have died of 9/11-connected asbestos exposure. 

    Following the vigil, an awards and recognition ceremony will take place. Public health leaders and dedicated asbestos advocates will receive awards. The evening will also feature a special music performance from Jordan Zevon, a singer and songwriter who advocates for awareness about the dangers of asbestos.

    9/11 Ongoing Health Crisis and Dr. Selikoff’s Enduring Legacy

    This year’s event begins the day following the 24th anniversary of the September 11 attacks. The conference will focus on the ongoing public health crisis affecting first responders and recovery workers exposed to asbestos at Ground Zero. First responders like firefighters have developed serious illnesses linked to asbestos, including mesothelioma, which can take decades to appear. 

    ADAO continues to honor them and push for safer conditions for first responders and the public. Reinstein says, “Our annual conference is a place to exchange life-saving knowledge, honor those we’ve lost, and galvanize our efforts to ban asbestos and prevent exposure.” 

    The theme of the 2025 conference is “Building on Dr. Selikoff’s Legacy in Asbestos Science, Prevention and Justice.” During the 1950s, New York physician Dr. Irving Selikoff discovered a pattern of serious illnesses among asbestos workers. By 1964 his work proved the toxic mineral increased the risk of several deadly diseases. 

    Dr. Selikoff pioneered and transformed our understanding of asbestos exposure and asbestos-related diseases. Reinstein notes, “Gathering together in New York City is especially meaningful as we reflect on the legacy of Dr. Selikoff and the sacrifices of 9/11 responders.”

    Academic Session at Mount Sinai Hospital

    The academic session on September 13 will run from 9 a.m. to 5 p.m. at Mount Sinai Hospital. Leading medical professionals, scientists, legal experts and advocates will present information across multiple topics. 

    Medical experts will cover new breakthroughs in diagnosis, treatment and prevention strategies. Legal experts and advocates will discuss efforts to hold companies accountable and the push for a global asbestos ban.

    2025 ADAO Conference Agenda

    • Session 1: From Then to Now, Selikoff’s Vision and Our Journey Forward
    • Session 2: Diagnosing and Treating Asbestos-Related Diseases
    • Session 3: Prevention Is the Cure, Strategies for Exposure Reduction
    • Session 4: Dr. Irving Selikoff, Paul Brodeur and Beyond 
    • Session 5: Asbestos and the Law

    Tickets are still available for people who want to join. Visit ADAO’s official conference site to register and learn more.

    paper with magnifying glass

    Free Mesothelioma Resources

    Get Access to Free Resources for Patients & Loved Ones


    Continue Reading

  • MENA commerce: Consumer insights, peaks, & growth in UAE and Saudi. – Think with Google

    1. MENA commerce: Consumer insights, peaks, & growth in UAE and Saudi.  Think with Google
    2. Voice of the Consumer 2025: Saudi Arabia findings  PwC
    3. UAE and Saudi Arabia’s generative AI adoption hits 58 percent, outpacing European markets: Report  Economy Middle East
    4. Cost, technology and local food trends reshape consumer choices in Saudi Arabia  PwC

    Continue Reading

  • Wall Street indexes rise as data keeps rate cut views intact – Reuters

    1. Wall Street indexes rise as data keeps rate cut views intact  Reuters
    2. Stock market today: Dow, S&P 500, Nasdaq futures stall as signs of labor-market cracks boost rate-cut bets  Yahoo Finance
    3. S&P, Nasdaq subdued as traders assess U.S. private payrolls data  Investing.com
    4. As investors brace for weak jobs data and Fed cuts, Sydney Sweeney powers a retail stock rally  Fortune
    5. US Markets Show Mixed Signals As Oil Slides And Payrolls Disappoint  Finimize

    Continue Reading