- Top 5 matches and storylines to watch on Friday at the 2025 US Open US Open Tennis
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- US Open 2025: Full order of play, Friday 5 September – all matches, complete daily schedule at Grand Slam tennis tournament Olympics.com
- Andy Roddick tells Felix Auger-Aliassime what he must do to beat Jannik Sinner in the US Open semi-final Tennishead
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Top 5 matches and storylines to watch on Friday at the 2025 US Open – US Open Tennis
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40 more Palestinians martyred in Israeli forces attacks on Gaza – RADIO PAKISTAN
- 40 more Palestinians martyred in Israeli forces attacks on Gaza RADIO PAKISTAN
- LIVE: Israel levels high-rise Gaza City tower, says ‘gates of hell’ opening Al Jazeera
- Death toll rises to 51 since dawn: hospital sources Dawn
- Israeli military says it controls 40% of Gaza City, plans to expand operation in coming days Reuters
- With Israeli advance looming, Palestinians in Gaza City ask when to leave and where to go AP News
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Rapid epigenomic classification of acute leukemia
Tuesday 07 October 2025
08:00 [PDT] 11:00 [EDT] 16:00 [BST]
Alternative time zonesUnlock the potential for faster, more comprehensive leukemia characterization with this webinar from Dana-Farber Cancer Institute expert Salvatore Benfatto.
Acute leukemia (AL) is an aggressive form of blood cancer that requires precise molecular classification and urgent treatment. However, standard-of-care diagnostic tests are time- and resource-intensive and do not capture the full spectrum of AL heterogeneity, making diagnosis and basic research investigations into AL a challenge. Researchers at Dana-Farber Cancer Institute (MA, USA) have developed MARLIN (methylation and AI-guided rapid leukemia subtype inference), a machine learning tool currently for research use only that enables the rapid classification of acute leukemia using real-time DNA methylation data generated by Oxford Nanopore sequencing. In both retrospective and prospective studies, Oxford Nanopore sequencing enabled MARLIN to deliver accurate molecular subtyping within two hours. This approach highlights the potential of nanopore technology to support faster, more comprehensive leukemia characterization.
REGISTER NOWWhat will you learn?Who may this interest?Speaker
What will you learn?
- How the leukemia classification approach developed by Dana Farber offers a framework that can be easily implemented anywhere in the world.
- How research with Oxford Nanopore sequencing is unlocking the potential to shorten the diagnosis and classification of acute leukemia to within hours.
- Why rapid and accurate treatment for acute leukemias is crucial to survival rates.
Who this may interest?
- Cancer researchers: basic and translational
- Core lab directors, managers and technicians
- Clinical lab directors, managers and technicians
Speaker
Salvatore Benfatto
Postdoctoral researcher
Dana-Farber Cancer Institute (MA, USA)
Salvatore Benfatto is a postdoctoral researcher at the Dana-Farber Cancer Institute. As a computational biologist, he works at the intersection of artificial intelligence and cancer research. In a multidisciplinary team, he develops machine learning models to foster the next generation of rapid DNA methylation- and AI-powered cancer diagnostics.
In association with
Submit Your Research to the F1000Research Genomics & Genetics Gateway
Advance the fields of genomics and genetics by publishing your research with the F1000Research Genomics & Genetics Gateway. With trusted publishing, open access, and transparent peer review, your work will uphold the highest standards of rigor and integrity while driving innovation in PCR, sequencing, and genetic analysis.
Join a platform that values transparency, openness, and author control. Submit your research today at F1000Research Genomics & Genetics Gateway.
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Microbial consortia-mediated rice residue decompositon for eco-friendly management
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Swiftie boyfriends face proposal pressure: ‘Taylor and Travis put you on the clock’ | Taylor Swift
Colleen O’Connor knows it sounds strange, but she thinks of Taylor Swift as a friend. The pop singer is 35; O’Connor, who works in public relations and lives in Long Island, New York, is just one year younger. “I’ve been a fan since day one, back in high school, and she’s been there through every phrase and journey of my life,” O’Connor said.
So when Swift announced her engagement to NFL star Travis Kelce last week, O’Connor reacted as many thirtysomething women do when they learn that a girlfriend secured a ring. First, she screamed so loudly her boyfriend thought someone had died. Then she wondered aloud to him: “When’s it going to happen for us?”
“It would be fun to be engaged with her at the same time,” O’Connor said. “I’ve been showing my boyfriend photos of the ring and saying how unique it is. That’s not my style, but we talk about what I might like.”
O’Connor is not the only one. Swift’s Instagram announcement – a photo in which she and Kelce embrace in front of an elaborate floral arrangement – raked in more than 1m likes in less than 10 minutes; it’s now up to 36m. “We needed this,” read one Vogue editorial. New York Times columnist and chick lit author Jennifer Weiner agreed: “Maybe love still wins.”
On social media, fans spoke of the news with parasocial investment. One cringe-inducing poem widely shared in the wake of the news read:
The day
Taylor Swift
got engaged,little girls screamed,
grown women cried,and the awkward child
we all carry insidefinally felt
chosen.A big day for little girls and grown women perhaps, but D-day for the people dating Swifties. “How do I tell my boyfriend he needs to propose ASAP so I can be engaged at the same time as Taylor Swift without sounding crazy,” one fan tweeted. “When I’ve been with my boyfriend longer than Taylor swift has been with Travis kelce yet THEYRE ENGAGED? we literally have a child IM HEATED,” wrote another.
On TikTok, boyfriends of Swifties posted informative videos about her career and history to help each other follow along with their partner’s excitement. “It’s time to get the ring, because Taylor and Travis put you on the clock,” said one comedian on the app. “Showed this to my bf,” a follower commented. “Me and my boyfriend have been together for 7 years … when he comes home I’m gonna start an argument and show him Taylor’s ring,” wrote another.
O’Connor’s boyfriend also feels the half-serious pressure. “Anytime I say something about Taylor and her wedding, he kind of rolls his eyes and says: ‘I know, I know,’” she said.
Taylor Swift performs onstage during the Eras tour in Cincinnati, Ohio, on 30 June 2023. Photograph: Taylor Hill/TAS23/Getty Images for TAS Rights Management Elisabeth Kramer, a wedding coordinator based in Portland, Oregon, said it is too early to tell how Swift’s wedding – which does not yet have a date – will affect the industry. But she is banking on some trends emerging from it. “I definitely see it being part of the conversation for my 2026 clients,” Kramer said. “Whatever she chooses to wear is going to set a huge tone for the next couple of years.”
Swift’s engagement may be a boon for the wedding industry, which saw a post-Covid boom that is slowing down amid inflation and the current economic climate. (One survey found that fewer Americans are planning to have weddings this year, down from 7% in 2024 to 4% in 2025.) “I’m hearing from a lot of vendors that 2026 is going to be a lot quieter, with people more hesitant to spend money,” Kramer said. “I’m interested to see how a Taylor-Travis engagement changes that. Maybe people see them getting engaged and think: ‘This is an OK thing to do.’”
Celebrity weddings encourage copycat brides, especially when it comes to dresses. Princess Diana’s taffeta wedding gown inspired countless dupes. Carolyn Bessette-Kennedy’s sexy, simple bias-cut dress defined 90s sleekness, while Kate Middleton’s lace Alexander McQueen frock brought back bridal sleeves.
Julie Sabatino, founder of the wedding styling company The Stylish Bride, predicts that Swift’s pick might join the ranks. “She’s no stranger to a gown,” Sabino said, alluding to the series of ballgowns Swift donned for her Eras tour. “I wouldn’t say the ballgown wedding dress has ever gone out of style, but maybe people who wouldn’t have considered it will now.”
O’Connor, the wannabe bride, said that Swift’s engagement has become “a new joke” between her and her boyfriend, as the pair makes light of their unmarried status. But for now, she is not holding her breath. “We just have a lot going on at the moment,” O’Connor said. “But she’s definitely planted a little extra seed.”
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Final entry lists published for World Athletics Championships Tokyo 25 – worldathletics.org
- Final entry lists published for World Athletics Championships Tokyo 25 worldathletics.org
- Athletes go for gold Inside Time
- How to watch the 2025 World Athletics Championships online for free Mashable
- World Athletics Championship 2025: dates, timetable, results and how to watch, explained The Sun
- World Athletics Championships Tokyo 25: Preview and how to watch track and field action live Olympics.com
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Israel bombs high-rise towers as brutal Gaza City assault intensifies | Israel-Palestine conflict News
Israel’s forces have destroyed a high-rise tower in a densely populated part of Gaza City and have warned of further attacks to multi-storey buildings as it intensifies its campaign to seize control of the capital.
On Friday, the Israeli military ordered people in Mushtaha Tower, a 12-storey building located on the western side of Gaza City and surrounded by hundreds of makeshift tents, to evacuate, and later struck the building, claiming it was “Hamas infrastructure” and was used to plan and carry out operations against Israeli forces.
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Reporting from Deir el-Balah in central Gaza, Al Jazeera’s Hind Khoudary said the building was one of the biggest high-rises in the heart of Gaza City.
“Israeli forces hit it with two air strikes – the first was a warning and then it was hit again with another F-16 strike,” she said.
The management of the Mushtaha Tower has denied Israeli claims that the high-rise was being used by Hamas fighters, according to Al Jazeera Arabic. The building’s management said the site was only accessible to displaced people.
Al Jazeera’s Tareq Abu Azzoum, also reporting from Deir el-Balah, said a number of civilians were wounded in the Israeli attack on the 12-storey tower and were transported to al-Shifa Hospital to receive emergency treatment.
“The shock wave of the attack spread over the entire area, triggering chaos. A number of makeshift tents have been affected by the attack, which signals a new phase of the Israeli military campaign,” he said.
‘Gates of hell are opening’
Prior to the attack on the tower, Israel’s Defence Minister Israel Katz said on X that Israel’s military activity in Gaza City is intensifying. He said the “gates of hell are opening now” in Gaza and warned that they will not be closed until Hamas “accepts Israel’s conditions for ending the war – led by the release of all the hostages and disarmament”.
Reporting from Gaza City, Al Jazeera’s Hani Mahmoud said Israel’s attacks on high-rises in the region are not yet over.
He said another five-storey building is facing Israel’s forced evacuation order.
“This is a building near a gas station and the YMCA, a nonprofit organisation. People are being given a short amount of time to evacuate,” he said.
Military analyst Elijah Magnier told Al Jazeera that Israel is targeting high-rise buildings in Gaza to minimise its potential troop casualties when they advance on the ground, while also spreading “panic and fear” among the civilian population.
“It also has a psychological advantage,” he noted. “Destroying the skyline creates shock, disorientation, fear and panic among civilians” who have “no visibility of the future or when this war will end”.
“This is a preparation to occupy Gaza City,” he said.
‘The operation will continue’
On Friday, an Israeli military spokesperson claimed that Israel controls 40 percent of Gaza City.
“We continue to damage Hamas’s infrastructure. Today we hold 40 percent of the territory of Gaza City,” Israeli Brigadier General Effie Defrin told a news conference, naming the Zeitoun and Sheikh Radwan neighbourhoods. “The operation will continue to expand and intensify in the coming days.”
Israeli forces killed at least 44 people across Gaza on Friday, with at least seven children killed in attacks in Gaza City alone.
Al Jazeera’s Khoudary said Palestinians have begun heading south due to the attacks in Gaza City.
“Tents have been filling up in az-Zawayda, al-Mawasi, Khan Younis and Deir el-Balah,” she said. “Palestinians must either survive by going south or stay in Gaza City – and we do not know what’s going to happen if they stay. There’s fear and desperation here.”
Palestinian and United Nations officials, however, say nowhere is safe in Gaza, including areas Israel designates as humanitarian zones.
Since the start of Israel’s war in October 2023, at least 64,231 people have been killed and 161,583 wounded across Gaza. A total of 1,139 people were killed in Israel during the October 7 attacks, and about 200 were taken captive.
Hamas releases video of two hostages
On Friday, Hamas released a video of two Israeli captives seized from a music festival in Israel in October 2023. Guy Gilboa-Dalal and Alon Ohel are two of 48 people still being held by Hamas in Gaza, with 20 thought to be still alive.
The video was edited and featured an exhausted-looking Gilboa-Dalal speaking for around three-and-a-half minutes. He says he is being held in Gaza City along with several other captives and that he is afraid of being killed by Israel’s offensive on the city.
Gilboa-Dalal appears to be in the backseat of a car that is being driven around. As the car passes by buildings, he identifies one as belonging to the Red Cross. At one point, Ohel is also seen.
After the release of the video, Israeli opposition leader Yair Lapid on X urged Israeli negotiators to resume truce talks on a deal to secure the captives.
Tens of thousands of Israelis have also staged weekly demonstrations calling for an end to the war to secure the release of the remaining captives.
Those freed so far were released as a result of diplomatic negotiations mediated by the United States and Arab states, but the last round of talks collapsed in July.
While Hamas has said it would accept the proposal put forward in July that would see the release of some captives in exchange for a temporary ceasefire, Netanyahu has been pushing for an all-or-nothing deal with Hamas in which the group releases all captives and surrenders.
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Pakistan’s services exports rise 18.27 pct in July-Xinhua
ISLAMABAD, Sept. 5 (Xinhua) — Pakistan’s exports of services rose sharply in July 2025, reaching 745.52 million U.S. dollars, marking an 18.27 percent year-on-year increase, according to the data released by the Pakistan Bureau of Statistics on Friday.
Meanwhile, imports of services also edged up slightly to 871.44 million dollars, representing a marginal decline of 0.61 percent in July compared to 876.83 million dollars in the corresponding month last year.
Month-on-month, exports rose 4.47 percent in dollar terms, while imports grew 3.41 percent, showing continued momentum in Pakistan’s services sector.
The services trade deficit stood at 125.92 million dollars in July 2025, narrowing by 2.44 percent from June and declining 48.91 percent year-on-year, according to data from the bureau. ■
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Snapchat Introduces Imagine Lens with AI Image Generation for Snaps
Snapchat is introducing a new Imagine Lens feature, which lets you create AI-generated images with text prompts, and it is available for Snapchat+ Platinum and Lens+ subscribers.
Snapchat announced Imagine Lens in its blog post today. As the name implies, it lets you create a custom lens by giving a text prompt, which you can edit later to get the desired effect. You can ask it to “create an image of a fluffy dog” or “turn me into a robot,” and it will use AI to generate the image.
Image Credit: Snapchat It also features some pre-made effects like “Turn me into a four to five-panel comic where something unexpected but heroic happens”, “Make me into a funny caricature,” and “Make this person skydive.” Of course, you can edit the prompt by tapping on the caption bar and modify it according to your preference.
It essentially allows you to create your own lens, something you could only do from Snapchat Lens Studio till now. The Imagine Lens feature will be available from Snapchat’s Lens carousel, and within the exclusive category. However, you will need a Snapchat+ Platinum or Lens+ subscription to use this exclusive Lens.
Snapchat has been adding AI features to its app prior to everyone else, with MyAI and other image creation features. So it was inevitable that AI lens creation was going to come to the app sooner rather than later. As for the underlying model, the platform is said to be using a mix of its own in-house and industry-leading AI models for the Imagine Lens feature.
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US Dollar Index sinks below 98.00 as Fed rate cut bets pick up pace
- The Greenback loses further momentum on Friday, en route to weekly losses.
- Investors have practically fully priced in a Fed rate cut later in the month.
- The US Nonfarm Payrolls added a meagre 22K jobs during the last month.
The Greenback’s decline picks up pace on Friday, sending the US Dollar Index (DXY) to the area of multi-week lows near 97.50, reversing at the same time the previous week’s small advance.
Rate cut bets increase further
The US Dollar rapidly leaves behind Thursday’s uptick and refocuses on the downside as investors now appear more convinced that the Federal Reserve (Fed) will trim its interest rates at the September 16-17 meeting.
Indeed, traders’ bets for further easing by the Fed were boosted after US Nonfarm Payrolls showed the economy added just 22K jobs last month, coming in short of forecasts (75K jobs) and lower than July’s 79K jobs gain.
Additional data supporting the above scenario comes from the jobless rate, which edged higher to 4.3%, accentuating the loss of momentum in the US labour market.
In the meantime, implied rates now see 70 basis points of easing pencilled in by year-end and around 153 basis points by the end of 2026.
Technical landscape
Next on the downside for DXY emerges its weekly low of 97.10 (July 24), seconded by the 2025 bottom at 96.37 (July 1) and the February 2022 valley at 95.13 (February 2).
On the upside, the immediate hurdle comes at the August high at 100.26 prior to the weekly top at 100.54 (May 29) and the May ceiling at 101.97 (May 12).
Momentum signals remain mixed: The Relative Strength Index (RSI) has cooled to about 44, showing fading bullish energy, while the Average Directional Index (ADX) is sitting near 11, a level that signals the market lacks a strong trend.
Nonfarm Payrolls FAQs
Nonfarm Payrolls (NFP) are part of the US Bureau of Labor Statistics monthly jobs report. The Nonfarm Payrolls component specifically measures the change in the number of people employed in the US during the previous month, excluding the farming industry.
The Nonfarm Payrolls figure can influence the decisions of the Federal Reserve by providing a measure of how successfully the Fed is meeting its mandate of fostering full employment and 2% inflation.
A relatively high NFP figure means more people are in employment, earning more money and therefore probably spending more. A relatively low Nonfarm Payrolls’ result, on the either hand, could mean people are struggling to find work.
The Fed will typically raise interest rates to combat high inflation triggered by low unemployment, and lower them to stimulate a stagnant labor market.Nonfarm Payrolls generally have a positive correlation with the US Dollar. This means when payrolls’ figures come out higher-than-expected the USD tends to rally and vice versa when they are lower.
NFPs influence the US Dollar by virtue of their impact on inflation, monetary policy expectations and interest rates. A higher NFP usually means the Federal Reserve will be more tight in its monetary policy, supporting the USD.Nonfarm Payrolls are generally negatively-correlated with the price of Gold. This means a higher-than-expected payrolls’ figure will have a depressing effect on the Gold price and vice versa.
Higher NFP generally has a positive effect on the value of the USD, and like most major commodities Gold is priced in US Dollars. If the USD gains in value, therefore, it requires less Dollars to buy an ounce of Gold.
Also, higher interest rates (typically helped higher NFPs) also lessen the attractiveness of Gold as an investment compared to staying in cash, where the money will at least earn interest.Nonfarm Payrolls is only one component within a bigger jobs report and it can be overshadowed by the other components.
At times, when NFP come out higher-than-forecast, but the Average Weekly Earnings is lower than expected, the market has ignored the potentially inflationary effect of the headline result and interpreted the fall in earnings as deflationary.
The Participation Rate and the Average Weekly Hours components can also influence the market reaction, but only in seldom events like the “Great Resignation” or the Global Financial Crisis.Continue Reading
