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Tepotinib Generates Superior Responses in Adenocarcinoma vs Non-Adenocarcinoma MET Exon 14 Skipping NSCLC
Tepotinib (Tepmetko) demonstrated a superior objective response rate (ORR) and disease control rate (DCR) in patients with adenocarcinoma MET exon 14 skipping non–small cell lung cancer (NSCLC) compared with those with non-adenocarcinoma disease, according to a subanalysis of the REAL-MET study.¹

Findings from a subanalysis of the study, presented during the International Association for the Study of Lung Cancer (IASLC) 2025 World Conference on Lung Cancer, revealed that the ORR was 70.6% and 40.9% in patients with adenocarcinoma (n = 56) compared with non-adenocarcinoma (n = 23) MET exon 14 skipping NSCLC, respectively (P = .021). Specifically, in patients with adenocarcinoma, complete response (CR), partial response (PR), stable disease (SD), and progressive disease (PD) were reported in 0%, 64.3%, 23.2%, and 3.6%, respectively. These respective rates were 0%, 39.1%, 34.9%, and 21.7% in patients with non-adenocarcinoma. Additionally, the DCR was 96.1% vs 77.3% in those with adenocarcinoma and non-adenocarcinoma, respectively (P = .023).

“The present real-world analysis found that non-adenocarcinoma histology accounted for 29.1% of patients with MET exon 14 skipping NSCLC, with squamous cell carcinoma, sarcomatoid carcinoma, and adenosquamous carcinoma being the most common subtypes,” Ryota Saito, MD, of Yamanashi Prefectural Central Hospital in Japan, and coauthors wrote in a poster presentation of the data.

In February 2024, the FDA approved tepotinib for the treatment of patients with metastatic NSCLC harboring MET exon 14 skipping alterations.² The previous February 2021 accelerated approval of the agent was supported by data from the phase 2 VISION trial (NCT02864992).

What Were the Background, Design, and Patient Characteristics of the REAL-MET Study?

The retrospective, multicenter, real-world REAL-MET study was conducted at 6 centers in Japan, which included patients treated between August 2020 and December 2024 with MET exon 14 skipping NSCLC (n = 98).¹ In particular, the subanalysis portion of the study evaluated the efficacy and safety of tepotinib for the treatment of patients with non-adenocarcinoma—including squamous cell carcinoma and sarcomatoid carcinoma—and adenocarcinoma MET exon 14 skipping NSCLC.

Of note, the primary objectives included ORR per RECIST 1.1 criteria, progression-free survival (PFS), overall survival (OS), and safety.

Patients included on the study (n = 79) had adenocarcinoma (70.9%), squamous cell carcinoma (10.1%), sarcomatoid carcinoma (6.3%), adenosquamous carcinoma (5.1%), and not otherwise specified (NOS) subtypes (7.6%).

Furthermore, in patients with non-adenocarcinoma (n = 23) and adenocarcinoma (n = 56), the median age was 73 years (range, 65-89) and 75 (range, 55-90), respectively. More than half of patients in both groups were male (non-adenocarcinoma, 52.2%; adenocarcinoma, 64.3%), and the majority had an ECOG performance status of 0 or 1 (73.9%; 75.0%). More than half had stage IV disease (52.2%; 64.3%) and were smokers (52.2%; 60.7%). Most patients had PD-L1 expression of 50% or greater among those with non-adenocarcinoma histology (60.9%), with 37.5% having a PD-L1 expression of 50% or greater in those with adenocarcinoma histology. Moreover, most patients in both groups received tepotinib as first-line treatment (73.9%; 80.4%).

What Were the Additional Efficacy Data from the REAL-MET Study?

Among patients with squamous cell carcinoma (n = 8), the CR, PR, SD, and PD rates were 0%, 37.5%, 37.5%, and 25.0%, respectively; these rates in those with sarcomatoid carcinoma (n = 5) were 0%, 40.0%, 20.0%, and 40.0%, respectively. Patients with adenosquamous carcinoma (n = 4) had CR, PR, SD, and PD rates of 0%, 50.0%, 50.0%, and 0% respectively; these respective rates in those with NOS disease were 0%, 33.3%, 33.3%, and 16.7%.

“Median PFS and median OS after tepotinib therapy were superior in patients with adenocarcinoma than in those with non-adenocarcinoma histology, although the difference was not significant,” Saito and coauthors wrote in the poster presentation.

In particular, the median PFS was 5.3 months (95% CI, 3.8-6.8) in patients with non-adenocarcinoma compared with 10.4 months (95% CI, 8.0-12.8) in those with adenocarcinoma (HR, 0.77; 95% CI, 0.45-1.34; P = .35). The median OS was 16.0 months (95% CI, 3.8-6.8) compared with 24.4 months (95% CI, 15.2-33.5) in patients with non-adenocarcinoma and adenocarcinoma histologies, respectively (HR, 0.60; 95% CI, 0.31-1.14; P = .12).

In patients with squamous cell carcinoma, sarcomatoid carcinoma, adenosquamous carcinoma, and NOS disease, the median PFS was 4.7 months (95% CI, 2.7-6.8), 5.3 months (95% CI, 0.0-12.9), 8.1 months (95% CI, 0.4-15.9), and 3.6 months (95% CI, 1.4-5.8), respectively. Among patients with the respective disease histologies, the median OS was 16.0 months (95% CI, 0.3-31.7), 5.9 months (95% CI, 5.6-6.1), 30.8 months, and 13.4 months (95% CI, 10.6-16.1).

“Although PFS and OS were shorter in patients with non-adenocarcinoma than in those with adenocarcinoma, tepotinib demonstrated clinical efficacy in the former subgroup, suggesting that the drug is effective against MET exon 14 skipping NSCLC, including cases with a non-adenocarcinoma histology,” Saito and coauthors concluded in the poster presentation.

References
1. Saito R, Misawa K, Kato Y, et al. Efficacy of tepotinib against non-adenocarcinoma MET exon 14 skipping NSCLC: a subanalysis of the REAL-MET study. Presented at: International Association for the Study of Lung Cancer (IASLC) 2025 World Conference on Lung Cancer; September 6-9, 2025; Barcelona, Spain. Abstract P3.12.09.
2. FDA approves tepotinib for metastatic non-small cell lung cancer. FDA. Updated February 16, 2024. Accessed September 8, 2025. https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-tepotinib-metastatic-non-small-cell-lung-cancer
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September 8, 2025
Getting a Visa to Visit the U.S. Could Take Even Longer – The New York Times
1. Getting a Visa to Visit the U.S. Could Take Even Longer The New York Times
2. U.S.: visa applications now restricted to country of residence or nationality VisasNews
3. US: Immigration News Alert – September 8, 2025 Corporate Immigration Partners, PC
4. US ends third-country visa stamping: What it means and the changes travellers can expect The Times of India
5. Trump Announces US Visa Application Centres for Seven African Countries | Firstpost Africa Firstpost
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September 8, 2025
2025 Noche UFC Venum Fight Kits

Authentic Walkout Hoodies

Take your fight night style to the next level with the Noche UFC 2.0 Full-Zip Hoodies, also available in black and green variants. Matching the graphics shown on the jerseys, these hoodies showcase the ancient warrior spirit and the pride of Mexico’s independence. Built for comfort and performance, each hoodie comes with adjustable drawstrings, two zippered pockets, and a breathable premium stretch fabric that holds up while walking into the gym or watching the fights.

Wear the Legacy

From jerseys and hoodies to the authentic fight shorts, the Venum Noche UFC collection has got you covered. Whether you’re hitting the gym, walking out under the lights, or watching from home – Venum’s Noche UFC fight kits let you carry the same energy wherever you go.

Check out UFC Store today for the full collection!

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September 8, 2025
Task review – Mark Ruffalo’s druggy kidnap drama is so bleak it’s downright manipulative | Television & radio

Do you feel it? There is a ripple in the firmament, a vibration in the foundations, a bracing of the cosmos … yes, Mark Ruffalo is preparing to Act again. This time, he stars in crime drama Task, created by Mare of Easttown’s Brad Inglesby, as a former priest turned FBI agent nursing a great sorrow in the suitably grey environs of suburban Philadelphia. Tom Brandis ends every day in a drunken semi-stupor and begins every morning with prayer and a head-dunk into an ice-filled sink. Do you think we might be in for a meditation on guilt, sin and the possibility of redemption? Yes, I wearily agree.

So. Brandis is taken off the desk duties he has been assigned since his great sorrow. This is evidently connected to the sentencing hearing for a third-degree murder conviction he is due to attend next week, where his daughter Emily may be giving a family impact statement – but we will have to wait just long enough for it to feel outright manipulative before we get the full explanation of who killed who and how. Brandis is assigned to a new taskforce to investigate a series of armed break-ins at drug houses owned by the Dark Hearts biker gang, in the hope that arrests can be made before Philly is consumed by a turf war. He has three youngsters to help him: the charmingly arrogant, Catholic-raised Anthony (Fabien Frankel); the supremely competent Aleah (Thuso Mbedu); and the supremely incompetent Lizzie (Alison Oliver). Their single characteristics allow Brandis to prove his priestly credentials (God-talks with the lapsed Anthony), his generosity of spirit (this middle-aged man is not threatened by youthful ability!) and patience (I would return her to Quantico instantly, bearing a large label that read “Not fit for purpose”) and not much else.

Not fit for purpose? … Mark Ruffalo, Alison Oliver, Thuso Mbedu and Fabien Frankel in Task. Photograph: 2025 Home Box Office, Inc

The raids are being conducted by garbagemen and best friends Robbie (Tom Pelphrey) and Cliff (Raúl Castillo), who can tell from the trash cans on their route which dealers’ houses have recently disposed of drugs and filled up with cash. How they know which are Dark Hearts facilities and why they are specialising in those will again become clear in the fullness of time. They are accompanied on the raids by younger friend Peaches (Owen Teague), who you might suspect is marked for death the moment he expresses his joy at the fact that he has just become engaged. I couldn’t possibly comment.

Apropos nothing, Task ticks all the expected boxes. There are bloody shootouts, corpses and bags full of fentanyl instead of cash grabbed in chaotic getaways which will then require selling. Which requires finding a buyer. Which requires becoming further enmeshed in the drugs world – and more identifiable to those seeking to destroy you for killing their men and taking their 12 kilos of fentanyl in the first place. Especially as you also kidnapped a child witness in the process.

Now, Mare of Easttown was no picnic. But it had plenty of black humour and was full of vividly drawn, wholly believable family relationships and friendships that gave it a sense of life in the round. The criminality mattered because it affected people in all walks of life. Task, by contrast, is relentlessly bleak, humourless and narratively airless. It is not just the Brandis family that is crushed by terrible griefs and burdens. Robbie’s wife has left him and he is mourning the death of his brother Billy. His niece Maeve (Emilia Jones), Billy’s daughter, is dying by inches under the strain of looking after Robbie’s motherless children, which does not seem a fair trade for letting him move in with her after her father’s death left her with a house.

It flattens the characters into ciphers, deadens the story and as time goes on, makes the whole thing inescapably boring. It is not as if we haven’t seen everything on show before. Let’s find another way to propel a plot – or maybe even find another plot entirely – especially in Philadelphia.

But if formulaic yet weighty stuff is your bag, if gestures towards bigger issues rather than actual interrogations of them are all you’re up to at the moment, then a relatively enjoyable Task lies before you. For anything else, you can always rewatch Mare of Easttown.

Task aired on Sky Atlantic and is on Now in the UK. In the US it airs on HBO; in Australia it is on Max

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September 8, 2025
expert reaction to cohort study looking at CT scans before pregnancy and risk of birth defects and miscarriage

September 8, 2025

A cohort study published in Annals of Internal Medicine looks at CT scans before pregnancy and birth defects and miscarriage risk.

Prof Simon Jolly, Professor of Visceral Physics, University College London (UCL), said:

“The outcome of this study has important implications. As the editorial acknowledges, the carcinogenic potential of ionising radiation — from medical imaging or other natural sources — is well known. The carcinogenic risk of CT scans is generally considered to be insignificant compared to the benefit provided by the diagnostic images.

“However, the study suggests that there are increased risks from CT scans that have impacts beyond cancer. It highlights that the increased risk of pregnancy loss for patients receiving pre-conception CT scans — so, importantly, not just during pregnancy — is significant enough that other non-ionising imaging modalities, such as MRI and ultrasound, may need to be prioritised for women of child-bearing age or planning to conceive.

“It is important that this is investigated in more detail and either correlated or refuted in other patient cohorts. It should be noted that the statistical significance and fraction of total pregnancies means that there is an absolute as well as relative risk increase for pregnancies. It should also be noted that, whilst the impact of direct irradiation of the abdomen and pelvis results in the highest risk, there is still increased risk from CT scans to other parts of the anatomy which is worthy of further investigation.”

Prof Derek Hill, Professor of Medical Imaging Science, UCL, said:

“This large study from Canada involves data from more than 5 million pregnant women. It finds that women who had an x-ray CT scan in the month prior to conception had a modest increase in chance of a failed pregnancy (rising from about 10% to nearly 13% for a single CT scan) compared to women who had no CT scan. This risk rises if there were multiple CT scans in that month. The authors argue that in young women, alternative types of imaging to CT should be considered.

“While any failed pregnancy is hugely distressing, it is important not to over-interpret the results of this paper. Firstly, the use of potentially harmful ionising radiation (such as in a CT scan) is already based on the principle of keeping any dose as low as reasonably achievable. Hospitals are very aware of the risks of excess radiation exposure. Therefore, CT scans are used when there is a clear benefit to the patient that outweighs the risk. There usually isn’t a radiation-free alternative available that provides the same quality of information: if there were it would have been used instead. It is important to note the statement by the authors that “The findings should not hinder the use of CT imaging when indicated, given the widespread availability of and rapid access to CT technology and the quality of CT imaging for many conditions “.

“More fundamentally, this paper shows a link between CT scan in the month before conception, and the risk of failed pregnancy. It does not demonstrate that the radiation from the CT scan causes this increased risk. It seems quite likely that women who have a CT scan in the month before conception already have some sort of health problem that led to the need for a CT scan in the first place. And if they had multiple CT scans, the health problem was probably more serious. This same health problem may have increased their risk of failed pregnancy. The results in the paper do indeed point to this likelihood. The authors have an internal control in the paper: as consider which part of the body was imaged in the CT scan. They find that the increased risk resulting from a head CT scan is pretty similar to the increased risk from a pelvis CT scan. Yet a head CT scan gives a much lower dose to the reproductive organs than a pelvis CT scan. If the increased risk of pregnancy were due to radiation dose, we would have expected the pelvis CT scan to lead to a much bigger risk than a head CT scan. It therefore seems likely that at least some of the increased risk of failed pregnancy associated with a CT scan in the month before conception is a result of the health condition that led to the CT scan in the first place, rather than to the radiation dose from the CT scan.”

Comments below were gathered by the Australian SMC:

Associate Professor Alex Polyakov, Clinical Associate Professor at the Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne & Medical Director of Genea Fertility Melbourne, said:

“This impressive retrospective Canadian study, involving over five million pregnancies, examined whether CT scans carried out before conception might influence later pregnancy outcomes. The results showed a slight increase in miscarriage and congenital anomalies among women who had undergone CT scans before conceiving.

“At first glance, this sounds alarming. But the size of the increase was modest. For example, miscarriage occurred in about 10% of pregnancies without CT exposure, compared with 11.7% after a single scan. Such differences are statistically detectable in an extensive dataset, but may not be meaningful at the individual patient level. Another challenge is separating the effects of the scan itself from the reasons for having one. Women who undergo CT scans were more likely to have health conditions—such as diabetes, hypertension, or smoking—that themselves raise pregnancy risks. Also, a woman scanned for trauma, suspected cancer or serious medical condition may already have had an elevated baseline risk prior to a CT scan.

“Although the researchers attempted to adjust for these factors, some degree of ‘confounding’ almost certainly remains. Association does not equal causation: just because one event follows another does not mean the first causes the second. The study relied on health-care databases, which cannot capture every miscarriage, anomaly or patient characteristic. This means the absolute risks are likely to be somewhat imprecise.

“Overall, the findings should not discourage appropriate CT imaging. The study does not prove that CT scans before pregnancy cause harm. Still, it reinforces the principle of caution: use CT when necessary, but preference non-radiation producing alternatives, such as ultrasound or MRI, where they can provide the same answers. The issue of accessibility and cost would need to be considered, as CT scans are more widely available and are likely to be more cost-effective compared to other imaging modalities.”

Prof Gavin Pereira, Epidemiologist, Curtin University, said:

“The Ontario cohort study reports a modest dose response between CT before pregnancy and risks of miscarriage and congenital anomalies. The main concern is confounding by indication, since many scans are prompted by conditions that themselves raise miscarriage risk, including major trauma, acute abdominal or pelvic emergencies and severe infection, none of which are fully captured in routine data.

“Because the analysis includes only recognised pregnancies, collider bias is also possible: if CT lowers fecundability and lower fecundability is linked to miscarriage, conditioning on conception selects more resilient exposed women and attenuates the observed effect. These opposing biases act in different directions, so the true effect size remains uncertain.

“Replication should use designs that strengthen causal inference. Clinicians should continue to interpret the associations cautiously and, where clinically reasonable, prefer non ionising imaging.”

‘Exposure to Computed Tomography Before Pregnancy and Risk for Pregnancy Loss and Congenital Anomalies’ by Simard et al. was published in Annals of Internal Medicine at 22:00 UK time on Monday 8^th September 2025.

DOI: 10.7326/ANNALS-24-03479

Declared interests

Prof Simon Jolly: “I have not received industry funding for any of my research. I have received in-kind contributions from industrial collaborators in the Czech Republic (Nuvia) in the form of sheets of plastic scintillator material, but they work in the related field of health physics and background radiation monitoring, not in medical diagnostic imaging.

“I am otherwise solely funded for my research by UK government grants and have previously received an EU H2020 grant.”

Prof Derek Hill: “Derek is co-founder and director of Panoramic Digital Health, but this commercial relationship is unrelated to CT scanning and ionising radiation.”

Dr Alex Polyakov: None

Prof Gavin Pereira: None

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September 8, 2025
‘Performative male contest’ finds its way to UNC with matcha lattes and wired earbuds –

The contest lasted over an hour and the audience remained interactive throughout. The judging was based on applause, so contestants did their best to add their own flair during their turn. Some empathized with the female experience while others played popular indie songs like “Riptide” by Vance Joy.

“I’ve never heard so many men talk about menstruation before,” onlooker Lily Gray said.

One participant took another approach during their turn, holding a sign reading “My culture is not your costume,” feigning protest and emphasizing the real existence of performative men.

Performative male contestants hold a sign on Friday, Sept. 5, 2025.

Despite the contest’s goal of acting like a man, it was open to participants of all genders.

Gray attended the evening’s contest in support of her friend, Vivian, who was competing. She said she thought a girl should win the contest because only a woman would understand the true peak performative male, as the goal is to appease women.

“I guess you could be a performative male, but you can’t be a performative male as well as you can be a performative woman pretending to be a performative male,” Gray said.

Contestant Esther Yu found out about the contest after seeing one of the posters on her walk back from class.

“I was really just going to watch, and then 10 minutes before, I was like, what if I just compete instead?” Yu said. “I feel like I have all the qualities of [a performative male].”

Yu came ready to compete in a t-shirt from an indie music festival and “Adam’s Curse: A Future Without Men” by Bryan Sykes, a book describing a scientific theory about the possible extinction of men.

Though the aim was to win the embroidered sash that would offer the highest honor of the best “performative male,” there was little animosity between contestants, as they offered each other high-fives and fist-bumps in between turns.

While the contest was meant to poke fun at an internet trend, the positive turnout suggested genuine interest in student-based events. Gray said she thinks it should be a yearly tradition.

To get the day’s news and headlines in your inbox each morning, sign up for our email newsletters.

“It’s fun when we have student-run, non-UNC events like this,” Yu said. “And it’s just purely word of mouth.”

@dthlifestyle | lifestyle@dailytarheel.com

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September 8, 2025
The 12 Biggest Fits at the US Open 2025, Ranked

The matches have been played, the Honey Deuces have been sipped, the Secret Service has left the premises—and with that, the US Open 2025 comes to a close. Aryna Sabalenka defeated Amanda Anisimova for the women’s singles title on Saturday, while Carlos Alcaraz bested Jannik Sinner yesterday in a buzzy men’s final attended by many well-dressed celebrities and also President Trump.

Over the past two weeks in Queens, scores of famous people watched from the Arthur Ashe stands in their best tenniscore cosplay, while a select few managed to make the look all their own. Meanwhile, we also saw some major style moments unfold on the court. Early on, Alcaraz became a victor in our hearts by debuting the best buzz cut to hit the tennis world in years. A resurgent Naomi Osaka clipped various bejeweled Labubus (each with their own name, such as “Billie Jean Bling” and “Andre Swagassi”) onto her duffle bag, while Venus Williams carried her racquet in a fuzzy case custom-made by the Venice Beach brand ERL.

From Osaka’s sparkly charms to Jeremy Allen White’s perfectly worn-in Wrangler denim shirt, here are a dozen of the finest looks to grace the US Open 2025 tournament.

12. John Mulaney and Olivia Munn

Looks like somebody caught up on our “old money style” explainer!

XNY/Star Max

11. Gunna

As of late, Gunna has reinvented himself into a 5K runner—and a Miu Miu man. The rapper wore a dainty sweater from Prada’s little-sister brand with the main label’s America’s Cup sneakers. Looks great.

Sweater by Miu Miu, sneakers by Prada.

John Nacion/Getty Images

10. Bruce Springsteen

Is it just us, or does it feel like the blazer-and-jeans combo is hitting especially hard these days? Shoutout to the boss, who found the pairing’s perfect accessory: three tiny hoop earrings pierced into a single earlobe.

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September 8, 2025
WHO adds diabetes drugs to essential medicines list – NewsNation
1. WHO adds diabetes drugs to essential medicines list NewsNation
2. WHO updates list of essential medicines to include key cancer, diabetes treatments World Health Organization (WHO)
3. Weight of Consequences The Nation (Pakistan )
4. Bishal Gyawali: The 2025 WHO EML List is Just Out Oncodaily
5. WHO adds diabetes drugs to essential list: win for patient advocacy, says Pune NGO founder who pushed for insulin access at expert panel meet The Indian Express
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September 8, 2025
Selena Gomez Proves a Minidress Can Still Be Demure

Selena Gomez must mean serious business today, because she was spotted out and about in New York City wearing not one, but two statement outfits. Is she pulling off a busy day of Rare Beauty-related meetings? Or perhaps she is taking top-secret Hollywood meetings for her next big acting gig. Whatever the jam-packed schedule might entail, Gomez was sure to bring an impeccably-chic wardrobe along with her for the ride. And her two looks had a cohesive focus: Gomez sported minidresses that felt both polished and timeless.

For Gomez’s first outing, styled by Erin Walsh, the star stepped out in a bright red short-sleeves mini dress. (Clearly, tomato girl summer is still going strong.) She accessorized the piece with matching pointed red slingbacks. Later in the day, Gomez wore another short dress—in black and marked by a draped asymmetric sleeve detail. She again took the monochromatic route, pairing the dress with with a discrete pair of black peep-toe mules.

Photo: Getty Images

Given Gomez is always one to favor a more elegant silhouette (see: her many Old Hollywood red carpet dresses), it’s only natural that her take on a minidress is more demure, too. With the addition of high necklines and sleeves, her above-the-knee hemlines still managed to feel modest and work-appropriate. The two dresses are also the perfect transitional piece—just short enough for a hot summer day, yet covered enough to work with a jacket come fall. Though, given her impeccable street style record, something tells us Gomez will move on and be rocking an entirely new lineup of chic items next season.

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September 8, 2025
Today’s NYT Connections Hints, Answers for Sept. 9, #821

Looking for the most recent Connections answers? Click here for today’s Connections hints, as well as our daily answers and hints for The New York Times Mini Crossword, Wordle, Connections: Sports Edition and Strands puzzles.

Today’s NYT Connections puzzle is a tough one — though maybe not as tough as yesterday’s, which really tripped up some players. Read on for clues and today’s Connections answers.

The Times now has a Connections Bot, like the one for Wordle. Go there after you play to receive a numeric score and to have the program analyze your answers. Players who are registered with the Times Games section can now nerd out by following their progress, including the number of puzzles completed, win rate, number of times they nabbed a perfect score and their win streak.

Read more: Hints, Tips and Strategies to Help You Win at NYT Connections Every Time

Hints for today’s Connections groups

Here are four hints for the groupings in today’s Connections puzzle, ranked from the easiest yellow group to the tough (and sometimes bizarre) purple group.

Yellow group hint: Ended.

Green group hint: Have a hard coating of some kind.

Blue group hint: Swallow.

Purple group hint: Not cat, but…

Answers for today’s Connections groups

Yellow group: Finished.

Green group: Things with shells.

Blue group: Swig.

Purple group: ____ dog.

Read more: Wordle Cheat Sheet: Here Are the Most Popular Letters Used in English Words

What are today’s Connections answers?

The completed NYT Connections puzzle for Sept. 9, 2025.

NYT/Screenshot by CNET

The yellow words in today’s Connections

The theme is finished. The four answers are complete, done, over and through.

The green words in today’s Connections

The theme is things with shells. The four answers are egg, hard taco, M&M and snail.

The blue words in today’s Connections

The theme is swig. The four answers are belt, gulp, shot and slug.

The purple words in today’s Connections

The theme is ____ dog. The four answers are bull, lap, under and watch.

Watch this: iPhone Air Is a Wild Card – and Starts a Big Change for Apple

06:39

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September 8, 2025