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  • WCH Tokyo 25 preview: women’s triple jump | News | Tokyo 25

    WCH Tokyo 25 preview: women’s triple jump | News | Tokyo 25

    • World record-holder Yulimar Rojas entered to defend her title in first triple jump competition since 2023
    • Leyanis Perez-Hernandez tops world list in 2025
    • Thea LaFond, Shanieka Ricketts and Jasmine Moore on the hunt for more major medals

    From 2017 to 2023, the women’s triple jump was dominated by Venezuela’s Yulimar Rojas. The world record-holder is entered to defend her title at the World Athletics Championships Tokyo 25, but the past two years have not gone to plan for the eight-time global gold medallist.

    Rojas claimed a record fourth world triple jump crown in Budapest thanks to a last-gasp leap beyond 15 metres, but she was unable to compete at last year’s Olympic Games in Paris due to an achilles injury. She was also forced to withdraw from her planned comeback meeting last month, but seems determined to line up in Tokyo – in what would be her first triple jump competition since winning her third Wanda Diamond League title in Eugene in September 2023.

    Her return is highly anticipated, as it would see her compete back in the stadium in which she won her Olympic title in 2021, getting gold in Tokyo with a then world record of 15.67m.

    But right now, her competitive form is unknown, and while Rojas sits 62cm ahead of her rivals when it comes to personal bests – her world record now standing at 15.74m from 2022 – it’s Cuba’s Leyanis Perez-Hernandez who leads this year’s world top list.

    Perez-Hernandez, who claimed world bronze in Budapest, jumped 14.93m to win the world indoor title in Nanjing in March – a mark just five centimetres off her PB set in San Salvador in 2023. She has also jumped 14.92m and 14.91m outdoors this year and has achieved five of the top six winning marks. Her victories have included Diamond League meeting wins in Oslo and Brussels and at the Diamond League Final in Zurich.

    Her compatriot Liadagmis Povea has a PB – set in 2021 – that matches Perez-Hernandez’s 2025 best and Povea sits second on the world top list with 14.84m jumped in Brescia in July. The Olympic fourth-place finisher – who finished one spot ahead of her compatriot in Paris – will be looking to go at least one place better and make the podium in Tokyo.

    Three other athletes with 15-metre-plus PBs star on the entry list, and they filled the podium places in Paris.

    Thea LaFond became Dominica’s first Olympic medallist when she got gold in Paris with a national record of 15.02m. Jamaica’s Shanieka Ricketts secured silver and USA’s Jasmine Moore claimed bronze, five days before earning a medal of the same colour in the long jump. They will all clash again in Tokyo.

    Ricketts is second on the world rankings behind Perez-Hernandez, with her results including Diamond League wins in Doha and Rome, where she finished ahead of LaFond and Perez-Hernandez, respectively. Her season’s best of 14.64m was set in Rome.

    Moore also has a Diamond League win to her name, but that came in the long jump in Silesia. She was third in the triple jump in Oslo and Brussels and has a season’s best of 14.68m, set when retaining her US title. Tokyo will be the first global outdoor championship in which Moore has focused on a single event – rather than doubling in the long jump and the triple jump – since the Tokyo Olympics.

    LaFond, who added her Olympic title to the world indoor gold she won in 2024, has a season’s best just two centimetres off that mark – 14.62m. She was second in Doha and finished fourth at the Diamond League Final.

    Others to watch include Jamaica’s three-time NCAA gold medallist Ackelia Smith, Slovenia’s Neja Filipic and Germany’s Caroline Joyeux, who has added 68cm to her PB this year, surpassing 14 metres for the first time in Essen in June, when she soared 14.45m. She has broken the barrier in three competitions since, her performances including 14.42m in Madrid.

    Jess Whittington for World Athletics

     

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  • Lithium levels tied to Alzheimer’s disease and dementia

    Lithium levels tied to Alzheimer’s disease and dementia

    September 9, 2025

    At a Glance

    • Levels of lithium were significantly reduced in the prefrontal cortex of people with mild cognitive impairment and Alzheimer’s disease (AD).
    • In a mouse model of AD, a low-dose lithium salt in the diet reversed memory loss and prevented cognitive decline in aging mice.
    • While more study is needed, lithium replacement could be a potential approach to prevent and treat AD.

    Compared to mice with normal levels of lithium in the brain (left column), mouse models of Alzheimer’s disease have increased levels of amyloid beta deposits (top right) and tangled tau protein (bottom right).

    Yankner Lab

    The brains of people with AD have abnormal protein deposits called amyloid plaques and tau tangles. Despite much progress in understanding AD, there is still uncertainty about how the disease develops. Previous research has found that the balance of metals in the brain may play a role, but the nature of this role has been unclear.

    A research team led by Dr. Bruce Yankner at Harvard Medical School set out to explore how metal ions—charged atoms of metals—might affect brain function and AD. The researchers first looked at whether metals in the brain differed in those who have mild cognitive impairment (MCI) or AD. In MCI, which precedes AD, people have more difficulty thinking, remembering, and reasoning than normal for people their age.

    The scientists analyzed post-mortem brain samples to quantify 27 metals in certain parts of the brain. They compared levels from dozens of people with AD, with MCI, and with no cognitive impairment. The results were published in Nature on August 6, 2025.

    The team found significantly lower levels of naturally occurring lithium in the prefrontal cortex of people with MCI and AD. The prefrontal cortex, which controls memory and decision-making, is prominently affected in AD. None of the other metals were significantly altered in people with MCI.

    Prior studies suggested that metal ions may interact with amyloid plaques. So the researchers compared lithium in plaques with plaque-free regions in human brain samples. They found that lithium was highly concentrated in amyloid plaques, and that the amount of lithium in the plaques increased from MCI to AD. Lithium levels in plaque-free regions were also significantly reduced in AD samples. These results suggest that lithium is sequestered by amyloid plaques.

    The researchers next explored how lithium in the brain affected AD pathogenesis in mouse models by depleting it from the diet. AD mice fed a reduced lithium diet had significantly more amyloid plaque and tau tangles along with impaired learning and long-term memory. In aged mice without AD pathology, those fed a low-lithium diet showed increased levels of the plaque-forming amyloid protein and developed significant memory loss. Lithium depletion affected gene activity in major brain cell types.

    Next, the researchers tested whether replacing lithium might influence AD pathology. Lithium carbonate is used as a mood stabilizer to treat bipolar disorder. But the researchers found that it is highly attracted to negatively charged amyloid plaques. The team tested 16 different lithium salts to find an alternative and settled on the organic salt lithium orotate.

    The researchers tested lithium carbonate and lithium orotate in AD mouse models at low doses in drinking water. Treatment with lithium carbonate had little effect. But lithium orotate significantly reduced amyloid plaque burden and tau tangle accumulation. Lithium orotate also restored synapses and reversed memory loss in AD mice, yet lithium carbonate did not.

    Finally, the team evaluated whether dietary lithium could have a protective effect in normal brain aging. They found that low-dose lithium orotate prevented synapse loss and reversed cognitive decline in aging mice. Long-term treatment with lithium orotate did not show toxicity.

    “The idea that lithium deficiency could be a cause of Alzheimer’s disease is new and suggests a different therapeutic approach,” Yankner says. But, he cautions, “Before recommending lithium orotate, we need to determine the effective and safe dose range in people. We are planning a clinical trial of lithium orotate that will hopefully begin in the near future.”

    —by Karen Olsen, Ph.D.

    Related Links

    References

    Lithium deficiency and the onset of Alzheimer’s disease. Aron L, Ngian ZK, Qiu C, Choi J, Liang M, Drake DM, Hamplova SE, Lacey EK, Roche P, Yuan M, Hazaveh SS, Lee EA, Bennett DA, Yankner B. Nature 2025 Aug 6. doi: 10.1038/s41586-025-09335-x. Online ahead of print. PMID: 40770094.

    Funding

    NIH’s National Institute on Aging (NIA); Ludwig Family Foundation; Glenn Foundation for Medical Research; Aging Mind Foundation.

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  • CFTC Sanctions Colorado Trader and Illinois Company to Pay $200,000 for Spoofing

    CFTC Sanctions Colorado Trader and Illinois Company to Pay $200,000 for Spoofing

    WASHINGTON, D.C. — The Commodity Futures Trading Commission announced today it issued an order filing and settled charges against Brett Falloon and Flatiron Futures Traders LLC for spoofing in the E-mini S&P 500 and E-mini Nasdaq 100 futures markets on the Chicago Mercantile Exchange.

    Falloon and Flatiron must pay, jointly and severally, a $200,000 civil monetary penalty. Falloon is also banned from trading commodity interests for 12 months. Both parties were ordered to cease and desist violating the spoofing prohibition in the Commodity Exchange Act.

    The order finds that from May through December 2022, Falloon engaged in spoofing while trading on Flatiron’s behalf by placing bids and offers with the intent to cancel them before execution. 

    Falloon’s trading followed a pattern: He placed genuine orders that he intended to execute on one side of the order book while entering the spoof orders he planned to cancel on the opposite side. Once his genuine orders were filled, he canceled the spoof orders. His genuine orders were often aggressive, meaning they crossed the bid-ask spread and were immediately filled.

    Falloon’s spoof orders usually constituted a large percentage of orders resting at the top price levels. The aggregate number of contracts in his spoof orders outnumbered the contracts in his legitimate orders 5-to-1. 

    The order also finds Falloon placed the spoof orders with the intent of misleading other market participants. His conduct induced other traders to either cross the bid-ask spread to fill his genuine orders, or place resting orders at the best offer, allowing Falloon to fill his genuine orders faster, in larger quantities or at more favorable prices.

    The CFTC thanks CME Group Inc. for its assistance in this matter.

    The Division of Enforcement staff responsible for this action are Michelle Bougas, Brandon Wozniak, Brian Hunt, Kathleen Banar, and Paul Hayeck, as well as former Division of Enforcement staff Erica Bodin and Deputy Director Rick Glaser. 

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  • WCH Tokyo 25 preview: men’s long jump | News | Tokyo 25

    WCH Tokyo 25 preview: men’s long jump | News | Tokyo 25

    • Two-time Olympic champion Miltiadis Tentoglou to defend his title
    • Mattia Furlani seeking to add world outdoor title to world indoor gold
    • Jamaican talents and Diamond League winner Simon Ehammer also on medal hunt

    Two-time Olympic champion Miltiadis Tentoglou, a master of sticking to his task in search of victory, will defend his long jump title at the World Athletics Championships Tokyo 25.

    The 27-year-old Greek athlete stands top of this year’s world list with 8.46m achieved in June.

    Below him are a clutch of ambitious and talented challengers who have strong reasons to believe they can overcome the man who has so far amassed five global gold medals indoors and outdoors in the space of the last four years.

    One of the youngest of these, at 20, is Italy’s Mattia Furlani, who has been living up to the expectations he aroused by winning the 2022 European U18 title in a championship record of 8.04m and then the 2023 European U20 title in a championship record of 8.23m.

    Last year Furlani wowed his native Rome by taking European silver in a world U20 record of 8.38m, and he went on to take bronze at the Paris 2024 Olympics.

    Furlani has followed up with more senior achievements this year by winning gold at the World Indoor Championships in Nanjing with a leap of 8.30m.

    That came three years after Tentoglou first earned the honour in Belgrade and just a year after the Greek athlete beat him on countback to retain the title in Glasgow after both jumped 8.22m.

    Can Furlani add world outdoor gold to his world indoor crown? Or can the wily, super-competitive Tentoglou continue to hold this rising talent at bay?

    Among the others who will arrive in Tokyo with serious medal prospects will be Jamaica’s Tajay Gayle, world champion in 2019 and bronze medallist at the 2023 edition in Budapest, who stands third on this year’s top list with 8.34m.

    Gayle’s teammate Carey McLeod, who won world indoor bronze in 2024 having finished just one centimetre adrift of Tentoglou and Furlani, also has strong podium prospects.

    Meanwhile, Switzerland’s multi-talented Simon Ehammer will see if concentrating on this event will yield him another major medal to add to bronzes he took at the 2022 World Championships and last year’s European Championships.

    Having won the 2024 heptathlon title at the World Indoor Championships in Glasgow, he added European heptathlon silver in Apeldoorn in March, setting a national record of 6506 points.   

    This summer the long jump has been at the centre of his ambitions and in August he repeated his win in the 2023 Diamond League Final, this time registering 8.34m to beat Furlani by two centimetres.

    Ehammer’s 2025 best has been matched by two other challengers in Tokyo: Australia’s Liam Adcock, who won world indoor bronze this year with 8.28, and Jorge Hodelin of Cuba.

    Others to watch out for are the consistently effective Thobias Montler of Sweden, the world indoor silver medallist in 2022 who has jumped 8.25m this year, and China’s Shi Yuhao, who has managed 8.21m this year but has a personal best of 8.43m.

    Mike Rowbottom for World Athletics 

     

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  • Baaghi 4 box office collection day 5: Tiger Shroff film shows no improvement; makes ₹39 crore | Bollywood – Hindustan Times

    Baaghi 4 box office collection day 5: Tiger Shroff film shows no improvement; makes ₹39 crore | Bollywood – Hindustan Times

    1. Baaghi 4 box office collection day 5: Tiger Shroff film shows no improvement; makes ₹39 crore | Bollywood  Hindustan Times
    2. Baaghi 4 worldwide box office collection day 3: Tiger Shroff, Sanjay Dutt film lags behind Baaghi 3 over 1st weekend  Hindustan Times
    3. Baaghi 4 Box Office Collection Day 4: Just 24 Crores Away From Becoming Tiger Shroff’s #1 Post-COVID Grosser!  koimoi.com
    4. Six Films Clash at BO, Conjuring Wins, Lokaah Roars ..  indiaherald.com
    5. Tiger Shroff’s ‘Baaghi 4’ crashes to Rs 4.25 Crore on Monday, lowest in the series  Times of India

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  • Lady Gaga Expands ‘Mayhem Ball’ Tour With Second North American Leg

    Lady Gaga Expands ‘Mayhem Ball’ Tour With Second North American Leg

    Lady Gaga has more Mayhem for her North American fans. The singer announced a second leg in the U.S. and Canada for next spring, which will include a rescheduled date for her postponed Miami show.

    Gaga’s second North American leg of her Mayhem Ball Tour will kick off on Valentine’s Day next year in Glendale, Arizona. She’ll be hitting cities across the South and Midwest, including Atlanta, Austin, and Saint Paul, MN. She will also return for more shows in Los Angeles and New York. Produced by Gaga and her fiancé Michael Polansky, the tour is still currently in its first leg, with shows scheduled for Toronto and Chicago this month.

    The dates include a rescheduled show for her Miami fans. She was due to play the Kaseya Center last week, but postponed due to vocal strain. She recovered in time for her two Madison Square Garden shows this weekend, as well as an appearance at the Video Music Awards.

    Following the September dates, Gaga will head to Europe and the UK for more shows this fall. Her Australian dates will take place in December before she hits Japan in January.

    Gaga took home Artist of the Year at the VMAs, accepting her award at the start of the show before traveling from UBS Arena on Long Island to MSG in Manhattan for her show. She won for Best Direction and Best Art Direction as well and brought her trophies back to MSG with her, dancing with them during “Perfect Celebrity.”

    Mayhem Ball 2026 North American Leg

    Trending Stories

    Feb 14 — Glendale, AZ @ Desert Diamond Arena
    Feb 15 — Glendale, AZ @ Desert Diamond Arena
    Feb 18 — Los Angeles, CA @ Kia Forum
    Feb 19 — Los Angeles, CA @ Kia Forum
    Feb 28 — Fort Worth, TX @ Dickies Arena
    Mar 01 — Fort Worth, TX @ Dickies Arena
    Mar 04 — Atlanta, GA @ State Farm Arena
    Mar 05 — Atlanta, GA @ State Farm Arena
    Mar 08 — Austin, TX @ Moody Center
    Mar 09 — Austin, TX @ Moody Center
    Mar 13 — Miami, FL @ Kaseya Center*
    Mar 19 — New York, NY @ Madison Square Garden
    Mar 20 — New York, NY @ Madison Square Garden
    Mar 23 — Washington, DC @ Capital One Arena
    Mar 24 — Washington, DC @ Capital One Arena
    Mar 29 — Boston, MA @ TD Garden
    Mar 30 — Boston, MA @ TD Garden
    Apr 02 — Montreal, QC @ Bell Centre
    Apr 03 — Montreal, QC @ Bell Centre
    Apr 09 — Saint Paul, MN @ Grand Casino Arena 
    Apr 10 — Saint Paul, MN @ Grand Casino Arena

    *Rescheduled date

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  • Olivia Cooke Hit a ‘House of the Dragon’ Actor So Hard It Made Him Cry

    Olivia Cooke Hit a ‘House of the Dragon’ Actor So Hard It Made Him Cry

    Don’t mess with Olivia Cooke.

    The House of the Dragon star recalls a time she slapped a co-star on the HBO drama so hard she made him cry.

    The 31-year-old actress — who’s currently promoting her Prime Video thriller The Girlfriend — told British newspaper The i Paper about a Dragon scene she worked on with Tom Glynn-Carney. In the show, Cooke plays the regal Alicent Hightower and Glynn-Carney is her sniveling son, King Aegon Targaryen.

    The scene called for Alicent to slap Aegon and Glynn-Carney encouraged the actress do “do it for real.” After consulting with the stunt coordinator, who gave her permission, Cooke whacked him – hard.

    “I walloped him!” she recalled “I don’t know my own strength! It was a slap that resonated across the land! It made him cry! I mean, that was the reaction that he’d wanted for the cameras. But I felt awful. It was hideous. I’ve always felt sick and wanted to cry after doing any stunt work like that.”

    Far more seriously, Cooke also says that as much as Hollywood has progressed when it comes to shooting sex scenes in movies and TV shows, women are often still put into difficult positions on set.

    Cooke said actors are put into “really precarious and vulnerable situations” which are even worse for actors who are “just starting out and don’t have the vocabulary to say what they’re not comfortable with” and noted “women [will] often get labelled ‘difficult’ or ‘a bitch’ for speaking up” about their concerns.

    Cooke added that intimacy coordinators — which first widely introduced into the TV industry on HBO’s Game of Thrones — will “sense hesitation and become your voice” and advocate for the actor.

    “Showing intimacy, passion is an integral part of reflecting the human experience,” Cooke added, but that it should be accomplished on screen without feeling like “a chunk of yourself has been taken.”

    The third season of House of the Dragon is expected sometime next year, likely around the summer. Meanwhile, Cooke can be seen in The Girlfriend, a six-episode psychological thriller that stars Robin Wright as a mother whose life begins to unravel when her son (Laurie Davidson) brings home a manipulative new girlfriend (Cooke). The series premieres Wednesday on Amazon’s Prime Video.

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  • Vuelta a Espana: Egan Bernal wins after stage 16 shortened due to pro-Palestinian protests

    Vuelta a Espana: Egan Bernal wins after stage 16 shortened due to pro-Palestinian protests

    France’s Egan Bernal won stage 16 of the Vuelta a Espana that had to be shortened by eight kilometres because of pro-Palestinian protests.

    Protests aimed at the Israel-Premier Tech team have disrupted several stages of this year’s race, including stage 11 which was shortened without a winner last week.

    However, on Tuesday, the race directors decided the winner and took times early after “a big protest at three km before the finish line”.

    The stage was scheduled to run along a 168km stretch from Poio to Castro de Herville before it was cut short.

    In Sunday’s stage 15, a protestor caused a minor crash that involved Spain’s Javier Romo, who abandoned this year’s race on Tuesday saying he was “not feeling very well, mentally or physically”.

    The 26-year-old Movistar rider had suffered “only bruises” during the fall and was able to complete the race on Sunday but quit with 80km to go in stage 16.

    The team time trial in stage five was also disrupted when the Israel-Premier Tech team, owned by Israeli-Canadian businessman Sylvan Adams, were stopped on the road by a group of protesters holding Palestinian flags.

    Bernal, riding for Ineos Grenadiers, secured the victory on stage 16 in three hours, 35 minutes and 10 seconds, finishing ahead of Spanish rider Mikel Landa.

    France’s Brieuc Rolland took third place while British rider Finlay Pickering, 22, finished eighth.

    Two-time Tour de France winner Jonas Vingegaard remains top of the general classification with Joao Almeida 48 seconds behind, while Great Britain’s Tom Pidcock sits third.

    Friday will see another medium mountain stage stretching 143km from O Barco de Valdeorras to Ponferrada.

    The Israeli military launched a campaign in Gaza in response to the Hamas-led attack on southern Israel on 7 October 2023, in which about 1,200 people were killed and 251 others were taken hostage.

    At least 64,605 people have been killed in Israeli attacks in Gaza since then, according to the territory’s health ministry.

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  • Shingles Vaccine Market Projected to Hit Valuation of US$ 16.80 billion by 2033 | Astute Analytica – GlobeNewswire

    1. Shingles Vaccine Market Projected to Hit Valuation of US$ 16.80 billion by 2033 | Astute Analytica  GlobeNewswire
    2. Challenges in Shingles Prevention  Pharmacy Times
    3. Shingles Vaccine Opens to More Residents  VOCM
    4. 300,000 Brits Now Eligible for Shingles Vaccination  Vax-Before-Travel
    5. Health Matters: Shingles  WVUA 23

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  • BBC Verify Live: Using video to investigate reported strike on Gaza-bound flotilla

    BBC Verify Live: Using video to investigate reported strike on Gaza-bound flotilla

    Key government buildings burned in Kathmandu

    Paul Brown
    BBC Verify senior journalist

    Hugh plumes of smoke rising from the National Assembly buildingX

    As violent protests in the Nepalese capital Kathmandu continue, we’ve verified several clips showing the buildings of the National Assembly and the Office of the President on fire.

    One clip, filmed from an elevated position across the road from the National Assembly, shows thick smoke engulfing almost the entire building, with only its distinctive terracotta roofs visible at times.

    Another clip – filmed from ground level – shows jubilant protesters waving, taking videos and posing for selfies as smoke pours from the building.

    And we’ve seen similar scenes outside the Office of the President around 6.5km (4 miles) away, where demonstrators can be seen gathered on the eastern lawn while the building burns in front of them.

    When verifying such footage, we must be alert to the possibility of AI-generated content, as burning buildings are often seen in such material.

    In this case, the footage we’ve seen does not bear any obvious signs of AI-manipulation or generation.

    Events have also been captured from multiple angles which lends credibility to the footage being posted.

    Additional verification by Sherie Ryder and Kuma Malhotra.

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