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  • Alzheimer’s blood test could ‘revolutionise’ diagnosis

    Alzheimer’s blood test could ‘revolutionise’ diagnosis

    Fergus WalshMedical Editor, BBC News

    Getty Images A blood sample being checked against a brain scanGetty Images

    More than 1,000 people across the UK with suspected dementia are to be offered a blood test for Alzheimer’s disease which it is hoped could revolutionise diagnosis of the disease.

    The blood test can detect biomarkers for rogue proteins which accumulate in the brains of patients with the condition and will be used in addition to pen and paper cognitive tests, which often misdiagnose it in its early stages.

    Scientists leading the trial at University College London believe the blood test will improve the accuracy of diagnosis from 70% to more than 90% and want to see how that helps patients and clinicians.

    Patients will be recruited at 20 memory clinics as part of the study, which aims to see how well the test works within the NHS.

    Alzheimer’s disease is the most common form of dementia and is associated with the build-up in the brain of two rogue proteins – amyloid and tau – which can accumulate for up to 20 years before symptoms emerge.

    The new blood test, which costs around £100, measures a biomarker called p-tau217, which reflects the presence of both proteins.

    Previously, the only way to confirm Alzheimer’s was by specialist PET brain scans and lumbar punctures to extract cerebrospinal fluid.

    However, these “gold standard” tests are not part of routine Alzheimer’s diagnosis and only 2% of patients ever receive them.

    Professor Fiona Carragher, chief policy and research officer at the Alzheimer’s Society, said: “Our recent Lived Experience Survey revealed that only a third of people with dementia felt their experience of the diagnosis process was positive, while many reported being afraid of receiving a diagnosis.

    “As a result, too often, dementia is diagnosed late, limiting access to support, treatment and opportunities to plan ahead.”

    Now, the Alzheimer’s Disease Diagnosis and Plasma p-tau217 (ADAPT) trial has begun recruitment at a memory clinic in Essex, with 19 additional specialist NHS centres planned to be involved across the UK.

    The study is being led by scientists at University College London, and is supported by Alzheimer’s Research UK, the Alzheimer’s Society, with funding from the People’s Postcode Lottery.

    BBC News Dr Ashvini Keshavan and Prof Jonathan Schott, dressed in white lab coats, stand side by side in their laboratoryBBC News

    Dr Ashvini Keshavan and Prof Jonathan Schott, both of UCL, are leading the Blood Biomarker Trial

    Jonathan Schott, professor of neurology at University College London and chief medical officer at Alzheimer’s Research UK said he was “thrilled” to welcome participants onto the ADAPT trial.

    He described the trial as “a critical part of the Blood Biomarker Challenge, which we hope will take us a step forward in revolutionising the way we diagnose dementia.”

    Half the participants in the study will receive their blood tests results within three months while the others will be told after 12 months.

    The study team will establish whether providing results earlier helps speed up diagnosis, guides decisions about further investigations, and influences how both patients and doctors interpret and respond to the results.

    The impact of blood test results on quality of life will also be measured.

    If the trial is deemed successful, the blood test could become a standard part of Alzheimer’s diagnosis. This will be crucial in years to come as a raft of new drugs to combat early-stage disease are in the final stages of clinical trials.

    ‘Gamechanger’

    BBC News Steven Pidwill stands next to his wife Rachel Hawley, 72, who has Alzheimer's. BBC News

    Steven and Rachel have been together for over 50 years

    Steven Pidwell, 71, from north London, says an accurate, rapid blood test for Alzheimer’s, combined with new treatments, would be a “gamechanger” for families affected by the condition.

    His partner of more than 50 years, Rachel Hawley, was diagnosed with Alzheimer’s disease almost a decade ago.

    Steven told the BBC: “I think it would mean everybody’s idea of Alzheimer’s would change. We would treat Alzheimer’s more like having a disability, rather than sort of a curse, and something we can’t talk about.”

    A diagnosis of Alzheimer’s can be devastating but the couple say they refuse to let the disease spoil their time together.

    Rachel, 72, said: “I think I still have a very happy life, and am very lucky in all sorts of ways.”

    The couple were part of a group of patients with lived experience of Alzheimer’s, who helped researchers at UCL design the trial and the feedback to potential volunteers.

    The team at UCL expect to have results in around three years.

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  • All The Over 50 Year Old Singles Confirmed

    All The Over 50 Year Old Singles Confirmed

    The pods for Love Is Blind: Brazil Season 5 are about to open on Netflix, but this version has a twist in that all the singles are over the age of 50.

    Love is Blind challenges participants to find their perfect matches without basing their decisions on appearance, instead prioritizing emotional connection and affinity. In this edition, the focus is on the life experiences of those who believe it’s never too late to fall in love.

    RELATED: ‘Love Is Blind UK’ Season 2 Cast Photos & Netflix Episode Release Dates Schedule

    Just like the original Love Is Blind, where real-life couple Nick and Vanessa Lachey host the series, Brazil has Camila Queiroz and Klebber Toledo.

    Queiroz, who starred in HBO Max’s Scars of Beauty earlier this year, and fellow actor Toledo got married in 2018 and have hosted all five seasons of the Netflix dating series Love Is Blind: Brazil or Casamento ás Cegas: Brasil since its premiere in 2021.

    RELATED: ‘The Real Housewives Of Potomac’ Season 10 Cast Photos & Premiere Date Set At Bravo

    Over several weeks, the singles enter the pods hoping to find a connection and get engaged, sight unseen. When they finally meet face-to-face, the couples will move in together to get to know each other more and decide if they ultimately want to walk down the aisle and say, “I do.”

    When does Love Is Blind: Brazil Season 5 premiere on Netflix?

    Netflix has set the premiere date for Love is Blind: Brazil Season 5 for Wednesday, September 10.

    RELATED: ‘Love Island USA’ Season 7 Reunion Photos: All The Looks From Cast Confirmed For Peacock Special

    When do new episodes of Love Is Blind: Brazil Season 5 premiere on Netflix?

    The release of episodes for Love Is Blind: Brazil Season 5 will roll out in three phases.

    Phase 1 (September 10): Episodes 1-4
    Phase 2 (September 17): Episodes 5-8
    Phase 3 (September 24): Episodes 9-10 (focusing on the weddings)

    RELATED: ‘Below Deck Mediterranean’ Season 10 Cast Photos, Trailer & Premiere Date Set At Bravo

    Scroll through the photo gallery below to meet all the singles from Love Is Blind: Brazil Season 5.

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  • How Much Vitamin D Per Day Is Too Much?

    How Much Vitamin D Per Day Is Too Much?

    • Vitamin D is an essential nutrient that supports immune function, and heart, bone, muscle and nerve health.
    • Vitamin D can be made in your body from sunlight, but it is also found in salmon, egg yolks and supplements.
    • Too much vitamin D can cause severe symptoms such as nausea, vomiting and kidney stones.

    Many people supplement with vitamin D, especially during the colder months when it’s more difficult to get your daily dose from sunlight (since your skin makes vitamin D with sufficient sunlight exposure). But can you take too much vitamin D? How do you know when it’s too much? And could you actually die from taking too much?

    What Is Vitamin D?

    Vitamin D is a fat-soluble vitamin that’s necessary for good health in general but also for several specific functions in your body. You may have noticed that some milks tend to be fortified with vitamin D. This is because vitamin D helps your body absorb calcium, which is necessary to build strong bones. Vitamin D also supports muscle and nerve function, heart health and immunity. 

    Certain conditions can precipitate vitamin D deficiency, including aging, osteoporosis, neurological diseases, malabsorption disorders, kidney and liver diseases, depression, pregnancy and rickets.

    Your skin makes vitamin D when exposed to sunlight—but enough of your skin needs to be exposed and it needs to be for a long enough period. Even if you have enough skin exposure, certain things can shield your skin from absorbing enough sunlight, including pollution, sunscreen and melanin content (darker skin tends to not absorb sunlight as well as lighter skin, as darker skin provides protection from UV rays). Even what latitude you’re at and what season it is will influence your UV absorption and vitamin D production.

    How Much Vitamin D Do You Need?

    This amount depends on your age. Recommendations start at 25 mcg (1,000 IU) for newborns and go up to 100 mcg (4,000 IU) for adults. It’s important to note that these are recommended daily vitamin D intakes and include vitamin D from all sources—like food and beverages—not just supplements. 

    Sun exposure for adequate vitamin D production might be less than you think. Research suggests you can get enough vitamin D by exposing your arms and legs to sunlight (without clothing or sunscreen) at midday (between 10 a.m. and 4 p.m.) for 5 to 30 minutes at least twice a week.

    Besides sunlight and supplements, vitamin D is also found in some foods. It naturally occurs in egg yolks, mushrooms that have been exposed to UV light, and fatty fish like salmon, tuna and sardines. Some foods are also fortified with vitamin D, including milk, cereal and juice. 

    Can You Die from Too Much Vitamin D?

    The short answer is yes, you can die from too much vitamin D. 

    Many cases of vitamin D toxicity start as vitamin D deficiency. In analyzing the data, researchers found that people who were deficient in vitamin D—or presumed to be deficient based on living in colder regions—took vitamin D supplements in doses that were higher than what is recommended. Or the dose they supplemented with, combined with foods containing vitamin D, put them over the limit.

    Typically, this type of toxicity happens over time, as opposed to overdosing all at once with the vitamin. “Unlike other vitamins, vitamin D acts like a hormone, so an excess of it in your body can lead to other health problems, such as hypercalcemia (high levels of calcium in your blood),” explains Maria Laura Haddad-Garcia, editorial manager, nutrition and news, at EatingWell. “This buildup of vitamin D in your body may happen when you take very high doses of vitamin D for several months. Additionally, since vitamin D is fat-soluble, your body can’t get rid of it like it does with water-soluble vitamins.”

    It’s important to note that vitamin D toxicity does not occur with sun exposure, as the body limits how much vitamin D it makes from UV light. With that said, too much sun exposure carries other risks, including sunburn and skin cancer, so it’s still important to take proper precautions to avoid these risks. Keep in mind, though, that for the body to produce enough vitamin D, you do need some sun exposure without sunscreen. 

    Warning Signs of Vitamin D Toxicity

    Before vitamin D toxicity occurs, there are warning signs, these include:

    • Nausea
    • Vomiting
    • Muscle weakness
    • Confusion
    • Pain
    • Loss of appetite
    • Dehydration
    • Excessive urination
    • Thirst
    • Kidney stones

    If it’s not caught in time, vitamin D toxicity can progress to kidney failure, irregular heartbeat and eventually, death. If you’re taking vitamin D and are experiencing any of the warning signs, it’s important to stop supplementing and see a health care professional. 

    Our Expert Take

    Vitamin D is a necessary nutrient for many functions in our bodies and for overall good health. And like anything else, too much of a good thing is too much. If you’re already supplementing with vitamin D or wondering if you should be, the surest way to know if you’re on target is to request bloodwork from a health care professional to see the status of your vitamin D level. 

    Ultimately, the best way to get vitamin D is through sufficient safe sun exposure and foods that contain vitamin D. Egg yolks, mushrooms, fatty fish and fortified milk provide vitamin D plus a host of other nutrients that are necessary for good health. Recipes like our Spinach, Mushroom & Egg Casserole and Salmon with Sun-Dried Tomato Cream Sauce are a good place to start.

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  • Alcaraz on Sinner rivalry: 'We push each other to the limit' – ATP Tour

    1. Alcaraz on Sinner rivalry: ‘We push each other to the limit’  ATP Tour
    2. Sinner on injury concern after US Open SF: ‘Nothing to worry about’  ATP Tour
    3. Double delight as Alcaraz reclaims US Open trophy, top spot  Dawn
    4. Carlos Alcaraz: Six Grand Slam titles at 22 – are we witnessing greatest player ever in rivalry with Jannik Sinner?  Sky Sports
    5. Sinner’s reaction to US Open defeat shows why he and Alcaraz will tower over the tour for years to come  The Guardian

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  • Israel attacks Hamas leadership in Qatar: All to know | Israel-Palestine conflict News

    Israel attacks Hamas leadership in Qatar: All to know | Israel-Palestine conflict News

    Israel struck Qatar’s capital, Doha, on Tuesday, in missile attacks that it said were aimed at senior leaders of Hamas, including negotiators from the Palestinian group who have been engaged in talks on securing a ceasefire in Gaza.

    Qatar condemned the attack as a violation of international law and of its sovereignty, with multiple countries and blocs also lashing out at Israel.

    The attack came at a time when Qatar, one of the lead mediators between Israel and the United States, on the one hand, and Hamas on the other, had been trying to broker a ceasefire in Gaza, where Israel has killed more than 64,600 people since October 2023, when it launched a war on the Palestinian enclave.

    Here is what we know so far about Israel’s strikes on Tuesday:

    What happened in Qatar?

    On Tuesday, around 3pm local time (12:00 GMT), multiple explosions were heard in Doha, and dark plumes of smoke rose above the skyline.

    People reported hearing the explosions in neighbourhoods across the city. They were also audible at Al Jazeera’s office in the city.

    Soon after 4pm local time (13:00 GMT), Israel’s military confirmed that it had fired missiles into Doha, targeting a compound believed to be hosting Hamas political leaders. Shortly after, Qatar’s Foreign Ministry issued a statement condemning the attack.

    This is the first time that Israel has attacked Qatar, a country its own negotiators have visited repeatedly over the past two years for ceasefire talks mediated by the government in Doha.

    Where in Qatar did the attack take place?

    The attack took place in the West Bay Lagoon area in Doha, home to many foreign embassies, schools, supermarkets and residential compounds. The region is home to Qataris as well as residents from around the world.

    What has Hamas said?

    A Hamas official told Al Jazeera Arabic that the attack targeted Hamas ceasefire negotiators. The attack came as negotiators from Hamas were meeting to consider the latest ceasefire proposal put forth by the US.

    But Suhail al-Hindi, a member of Hamas’s political bureau, also confirmed that the group’s leadership, which was targeted in Doha, had survived the attack.

    Among those believed to have been targeted were senior leaders Khalil al-Hayya and Khaled Meshaal.

    But the attack killed al-Hayya’s son, Humam, and one of his top aides, al-Hindi told Al Jazeera. Contact had also been lost with three other bodyguards, he added.

    He stressed that the loss of any lives was tragic.

    “The blood of the leadership of the movement is like the blood of any Palestinian child,” al-Hindi said.

    What do we know about casualties?

    In addition to al-Hayya’s son Humam and an aide, Qatar confirmed late in the evening that at least one Qatari security official had died in the attack. Other members of Qatar’s security forces were wounded, the country’s Interior Ministry said.

    “Specialised crews are continuing to inspect and secure the targeted area with the explosives division of the internal security forces,” the ministry said in a statement.

    Hamas said six people had been killed in all.

    What has Israel said?

    The office of Israeli Prime Minister Benjamin Netanyahu released an X post on Tuesday saying Israel acted alone in the attack.

    “Today’s action against the top terrorist chieftains of Hamas was a wholly independent Israeli operation,” the post read.

    “Israel initiated it, Israel conducted it, and Israel takes full responsibility.”

    Netanyahu and Israel’s Defence Minister Israel Katz issued a joint statement justifying the attack and tying it to the shooting in occupied East Jerusalem on Monday in which six Israelis were killed.

    “The prime minister and defense minister believed the operation was completely justified in light of the fact that this Hamas leadership initiated and organized the October 7 massacre, and has not ceased to launch murderous actions against the State of Israel and its citizens since then,” the statement said.

    The strikes on Doha violate the United Nations Charter — breaching Qatar’s sovereignty and territorial integrity.

    Israeli opposition leader Yair Lapid lauded the attack in a social media post, saying: “Congratulating the Air Force, [Israeli army], Shin Bet and all security forces on an exceptional operation to thwart our enemies.”

    How have other Palestinian authorities reacted?

    Mustafa Barghouti, who is the secretary-general of the Palestinian National Initiative, said that the Israeli attack on Doha represents a “turning point that will have dangerous implications” for the Middle East.

    “This operation is against Qatar, which is leading the mediation efforts, and against the Hamas leadership that is discussing the American proposal,” Barghouti said. “Is there worse shamelessness?”

    How has Qatar reacted?

    Majed al-Ansari, a spokesperson for Qatar’s Foreign Minister, released a statement condemning the attack. “This criminal attack constitutes a flagrant violation of all international laws and norms and a serious threat to the security and safety of Qataris and residents of Qatar,” the statement reads.

    “While strongly condemning this attack, the State of Qatar affirms that it will not tolerate this reckless Israeli behavior and its continued tampering with regional security, as well as any action targeting its security and sovereignty. Investigations are underway at the highest level, and further details will be announced as soon as they become available.”

    What is the latest in Qatar?

    Qatar’s Interior Ministry said that the situation is safe and that the explosions heard in Doha were a result of an attack on Hamas residential headquarters.

    “The ministry confirms that specialised teams are working [at the scene], and the situation is safe, and calls on everyone to obtain information from official sources,” it said in a social media post.

    Qatar Airways confirmed in a statement that its flight operations have not been impacted.

    The statement reads: “The recent unfortunate events in Doha have not impacted Qatar Airways operations and there have been no disruptions as a result. The safety and security of our passengers have been and will always be our top priority.”

    The US Embassy in Qatar had placed a shelter-in-place order for its personnel. However, it lifted the order shortly afterwards.

    Several countries have condemned Israel’s attack on Qatar.

    Saudi Arabia’s Foreign Ministry said that it “condemns and denounces in the strongest terms the brutal Israeli aggression and the flagrant violation of the sovereignty of the sisterly State of Qatar”, adding that it affirms “its full solidarity” with the fellow Gulf state.

    Riyadh also warned of the “grave consequences resulting from the Israeli occupation’s persistence in its criminal transgressions and its blatant violation of the principles of international law and all international norms”.

    Turkiye’s Ministry of Foreign Affairs said the attack revealed that Israel was not interested in an agreement to end the war on Gaza.

    “The targeting of the Hamas negotiating delegation while ceasefire talks continue shows that Israel does not aim to reach peace, but rather continue the war,” the ministry said in a statement.

    United Arab Emirates (UAE) Foreign Minister Sheikh Abdullah bin Zayed Al Nahyan released a statement expressing solidarity with Qatar, calling the attack “blatant and cowardly”.

    The Iranian Foreign Ministry deemed the attack a “violation of international law”, Iranian media reported.

    Pakistani Prime Minister Shehbaz Sharif wrote in a social media post: “This act of aggression by Israel is totally unjustified, a brazen violation of the sovereignty and territorial integrity of Qatar, and constitutes a most dangerous provocation that could imperil regional peace and stability.”

    UN Secretary-General Antonio Guterres called the strikes a “flagrant violation” of the sovereignty and territorial integrity of Qatar.

    Egypt, Kuwait, Jordan, Iraq, Syria, the Maldives, Lebanon, Morocco, Algeria, and the Gulf Cooperation Council also all condemned the attack.

    French President Emmanuel Macron said in a post on X that the attack on Qatar was “unacceptable, whatever the reason may be”, expressing solidarity with Qatar’s emir. “War must under no circumstances spread in the region,” he added.

    The United Kingdom warned against the “further escalation of violence” in the region and said that it had no prior knowledge of the attack.

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  • Short-duration space station missions not part of NASA’s long-term plans

    Short-duration space station missions not part of NASA’s long-term plans

    WASHINGTON — The inclusion of a 30-day demonstration mission in revised plans by NASA to support development of commercial space stations does not represent a permanent shift to shorter missions.

    NASA officials used a Sept. 8 online industry day session to clarify aspects of a draft announcement for partnership proposals released Sept. 5 for the second phase of its Commercial Low Earth Orbit Destinations, or CLD, program.

    That second phase, called Commercial Destinations – Development and Demonstration Objectives, or C3DO, will use funded Space Act Agreements, rather than fixed-price contracts, awarded to several companies to advance development of their commercial space station concepts. The C3DO phase will culminate with a demonstration mission to a company’s station featuring four people spending at least 30 days there.

    That 30-day mission suggested a shift in how NASA plans to use space stations after the International Space Station, which is permanently crewed with individual missions lasting on average six months. A NASA policy directive in late July said earlier requirements for a “full operational capability” involving four-person crews on such stations continuously were no longer binding.

    However, at the industry day, Angela Hart, manager of the CLD program, said the language in the draft solicitation should not be interpreted as a permanent shift to short-duration missions.

    “I would not say that NASA has fully shifted to monthly crew rotations,” she said. “It is not NASA’s long-term goal to have only a one-month mission.”

    The solicitation, she said, does not set long-term requirements for services. That will be left to a future third phase of the CLD program, involving certification of such stations and purchases of services.

    Hart said NASA decided on 30 days as the length of that demonstration mission so that crews can fully test various systems on a commercial station while also doing research. “Thirty days is an adequate time for us to be able to test out all systems but also to provide a ‘minimum gap’ mission that would allow us to do certain science.”

    The “gap” reference is to a potential gap in U.S. human presence in low Earth orbit, or LEO, between the retirement of the ISS and the beginning of operations of commercial stations. NASA had once desired an overlap between the ISS and commercial stations but has more recently emphasized minimizing a gap between them.

    “Our development plans are not tied to the ISS lifetime or deorbit decisions, although NASA is very interested in reducing a gap, if at all possible,” she said. “The two are no longer tied. There isn’t a decision point that says when we have a CLD, we will end ISS.”

    However, NASA is still working to minimize, or eliminate, any gap in crewed presence in LEO. “We have partners that have been working on commercial LEO platforms in a variety of ways, but we really want to put that into hyperspeed and get to a place where we’re making the next big steps, and it is driven by the gap,” Brian Hughes, NASA’s chief of staff, said during a talk Sept. 9 at the Global Aerospace Summit here.

    “We don’t want the Chinese to be the only platform in LEO,” he said, citing the revised CLD strategy as a way to prevent that. “If we do that process right, and if we do it now, we should be able to prevent the gap.”

    The shift in NASA’s approach for CLD development, including at least an initial focus on short-term missions, has caused companies proposing such stations to reevaluate their plans. None, though, have announced any substantive changes to their proposed stations or business plans.

    “We’re still going ahead as is,” said Leslie Haas, executive vice president for business development in the space systems division of Voyager Technologies. She spoke during a session of the American Astronautical Society’s Glenn Space Technology Symposium Sept. 8, just before the NASA industry day.

    Voyager holds a 65% stake in Starlab Space, the joint venture proposing the Starlab commercial station that won funding in the first phase of NASA’s CLD program. She said the company plans to conduct a critical design review of its station in December, a schedule that would support a launch of its station in 2029.

    Haas said the company was looking for feedback from NASA about the changes in the program. “But overall, it’s still full speed ahead.”

    Representatives of two other companies on the panel also proposing commercial space stations, Blue Origin and Vast, declined to answer a question during the session about how NASA’s revised CLD strategy affected their plans.

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  • South Africa’s campaigners for healthy food

    South Africa’s campaigners for healthy food

    BBC Dozens of children sit at three long tables which are placed in the schoolyard. They are eating lunch from brightly coloured plastic plates. The picture is taken from above, so you can only see the tops of their headsBBC

    Pupils at Kairos School of Enquiry are served healthy, mainly vegetarian, meals

    It’s lunchtime in the leafy grounds of the Kairos School of Enquiry in Randburg, South Africa.

    Dozens of children line up excitedly in front of a table laden with large pots of fresh, hot food.

    “Today on the menu we have Kitchari: a mix of daal and rice, with tomato chutney, halloumi and salad,” the school cook says, as she serves the students.

    The school decided to introduce a mainly vegetarian food policy as part of an effort to buck a worrying global trend: for the first time, the number of overweight children has overtaken the number of underweight ones.

    Marc is a white man with brown and grey hair, and a small beard. He wears a brightly coloured blue shirt and smiles into the camera. The picture is taken outside, and he is surrounded by greenery.

    Headteacher Marc Loon has enforced a strict healthy foods policy at his school

    The UN says the number of overweight and obese teenagers around the world has nearly tripled in the last two decades.

    And the number of overweight children aged five to nine years old has increased from 69 million to 147 million.

    Parents at Kairos have been asked to pack only whole foods in their children’s lunchboxes.

    Headteacher Marc Loon believes the policy has provided an opportunity to teach students about the importance of healthy eating.

    “If all schools were to emulate our intention of being thoughtful and conscious of what children are putting into their bodies… the health of the children would be served,” he said.

    The growing popularity of convenience food in the developing world is partly responsible for the growth in obesity rates amongst children, according to Unicef.

    Trainee lawyer Mamkhabela Mthembu, 23, told the BBC that when she was younger fast food was a treat.

    “I grew up with my grandmother and not in the best circumstances,” she says. “Junk food was something that we looked up to because my granny didn’t always have money, so it was a token of celebration.”

    Because of this, she says she never thought of junk food as unhealthy. Instead, it became aspirational.

    But that changed when she moved to Pretoria aged 19 for university, where her student residence was on top of a fast food restaurant.

    With a busy schedule, she says she found herself choosing convenience food over cooking – and it’s had a lasting impact on her health.

    Mamkhabela Mthembu Mamkhabela is a young black woman. She wears a black, long-sleeved top and black leggings. Her braids are piled on top of her head in a large bun, and she stares directly into the camera.Mamkhabela Mthembu

    Mamkhabela Mthembu says she became overweight after indulging in junk food while at university

    “Now I am overweight, it’s something that I’m not proud of,” she says. “I had bleeding gums as a child from eating too many sweets which I still have today. I’m starting to have breathing problems.”

    Her struggles led her to become an advocate for Unicef in her spare time. She wants more students to be aware of the damage fast food can have on their health.

    Poor and middle income countries have seen the greatest surge in overweight and obese children.

    But whereas in poorer countries overweight children tend to be from wealthier families who can pay for high-calorie foods, in middle income economies like South Africa more people can afford to go to fast food restaurants.

    It has led to an explosion in the number of chains across the country. The South African fast food market was valued at $2.7bn in 2018 and is expected to reach $4.9bn by 2026.

    Gilbert is a middle aged black man. He is bald and wears a white shirt and a blue blazer with black glasses.

    Unicef’s Gilbert Tshitaudzi says the government needs to stop fast food companies advertising to children

    Unicef says more needs to be done to stop these companies from marketing to children and young people.

    “Previously, we would always blame an individual for not exercising enough, or not eating healthily,” says Gilbert Tshitaudzi, Unicef South Africa’s nutrition manager.

    “But we know now that that is not really the case. How do you expect an individual to live a healthier lifestyle if their environment does not enable them to do that?”

    He says they have advised the South African government to restrict the marketing of unhealthy food to children.

    The constant presence of convenience food is an additional challenge for parents who wish to keep their children healthy.

    Memory Padi’s eight-year-old daughter, Sophia, was diagnosed with rare autoimmune disease ADEM (Acute Disseminated Encephalomyelitis) when she was 18 months old.

    Sophia was given steroids shots to help with her symptoms but her mum believes they led her weight to balloon. She now weighs 107kg.

    “Her dietitians can see that this is not about food. They say she eats normally,” she says.

    Memory Padi Sophia in school - she wears a white polo neck top and black trousers and her black hair is intricately braided. She sits at a table in a classroom and appears to be concentrating on a book in front of herMemory Padi

    Sophia, eight, was given steroid shots to help with her rare autoimmune disease, but her mum believes they led her weight to balloon. She now weighs 107kg

    Memory has put her daughter on a low carb diet, but still struggles to maintain her weight.

    Supporters have set up social media pages to raise money for Sophia. Although Memory says she can’t afford fast food, well-wishers will sometimes buy it for her daughter as a treat.

    “We rarely go out, but when we do, she sometimes asks for fast food. She’s a child, so she wants these things.”

    Memory is currently unemployed and struggles to provide her daughter with the support she needs, including swimming lessons.

    She sometimes takes Sophia for walks around their neighbourhood in Alexandra, a township near Johannesburg’s northern suburbs, but the traffic and stares make her uncomfortable.

    Getty Images Four boys, two in orange t-shirts, stand at a pizza fast food counter ordering food with two drinks machines advertising Pepsi in the background Getty Images

    South Africa has seen an explosion of fast food chains across the country in recent years

    The South African government introduced higher taxes on sugary drinks in 2018.

    But it hasn’t stopped the growing obesity rate in children: 22% of children under five are overweight or obese in South Africa, up from 13% in 2016.

    Unicef says countries need to improve access to local, nutritious food for children and teenagers.

    “South Africa is known to be food-secure,” says Mr Tshitaudzi. “But many households don’t have money to access healthier options because of our high unemployment rate.”

    Back at the Kairos School, it’s break time. Children eat from lunchboxes filled with fruits, vegetables and sandwiches made from wholewheat bread.

    Until governments are able to implement policies that can reverse the surge in childhood obesity, it’s left to institutions and individuals to safeguard the health of future generations.

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  • Chappell Roan, Charli XCX and Doja Cat images among Music Photography Awards nominees

    Chappell Roan, Charli XCX and Doja Cat images among Music Photography Awards nominees

    Helen BushbyCulture reporter

    Josh Druding Chappell Roan wears a pink leotard emblazoned with stars, thigh-high boots with stars and a super hero mask. She is standing on a stage with one hand raised in the air.Josh Druding

    Josh Druding’s image of Chappell Roan performing live is up for music moment of the year

    Abbey Road studios has announced the nominees for its Music Photography Awards, after considering more than 20,000 submissions from 30 different countries.

    The photographs up for awards feature stars including Chappell Roan, Lana Del Rey, Charli XCX, Tyler the Creator, Pulp, The 1975, Maggie Rogers, Fontaines DC, Doja Cat, Central Cee and Burna Boy.

    Fans can vote for music moment of the year on the MPA’s website until 23 September and the awards ceremony will take place at London’s Abbey Road on 2 October.

    Mark Robertson, Abbey Road’s director of marketing and creative, thanked the “incredibly gifted community of photographers who continue to impress with their work”.

    He added the images “prove that music photography is a genuine art to be celebrated and plays a vital role in shaping culture”.

    The awards include two new categories this year – portrait and festivals – with an additional guest category called club culture.

    All 40 images from the eight open categories on display in Outnet’s Now Pop One venue in London, where photographs by the nominees can be seen between 19 and 23 September.

    Here are some of the nominees:

    Greg Noire Doja Cat and dancers on stage in furry white costumesGreg Noire

    Category: Live Music

    Photographer: Greg Noire

    Image: US rapper and singer Doja Cat performing on stage with her dancers in eye-catching furry costumes

    Pupat Chenaksara Charli XCX in a white, short outfit on all fours being showered with water on stagePupat Chenaksara

    Category: Music moment of the year

    Photographer: Pupat Chenaksara

    Image: British singer-songwriter Charli XCX getting soaked in the rain while singing on stage

    Connor Baker Smokey image of people dancing in a night clubConnor Baker

    Category: Club culture

    Photographer: Connor Baker

    Image: Glitterbox at Hï Ibiza, with clubbers mid-dance amid the smoke effect

    Jez Pennington Enter Shikari wearing a pink t-shirt and cream pants lies in a pool of mud while holding his mic in one handJez Pennington

    Category: Festivals

    Photographer: Jez Pennington

    Image: British rock band Enter Shikari at Download Festival, having a muddy experience

    Phoebe Fox Profile shot of The Cure's Robert Smith against a blue background. Smith is wearing black eye make up and red lipstick.Phoebe Fox

    Category: Judges choice

    Photographer: Phoebe Fox

    Image: British rock band The Cure’s lead singer Robert Smith shot in profile with his trademark hairstyle and make-up

    Kirby Gladstein Lana Del Ray in what looks like black bridal gear sits on the shoulders of a man in a black helmet and jacket as crowds photograph and film them on mobile phones.Kirby Gladstein

    Category: Music moment of the year

    Photographer: Kirby Gladstein

    Image: US singer-songwriter Lana Del Ray is wearing what looks like a black bridal ensemble

    Platon A black and white picture of Nile Rodgers' hand holding a plectrumPlaton

    Category: Judges Choice

    Photographer: Platon

    Image: The crucial right hand of US musician, songwriter, guitarist and record producer Nile Rodgers, who is also the co-founder of disco band Chic

    Annie Noelker Benny Blanco sitting in a restaurant putting a spoonful of food into his mouth. A vegetable dish is on the table in front of him.Annie Noelker

    Category: Portrait

    Photographer: Annie Noelker

    Image: US record producer and songwriter Benny Blanco is getting his five-a-day in a restaurant

    Lantz Martin A side view of US rapper and record producer Ken Carson in black and whiteLantz Martin

    Category: Emerging photographer of the year

    Photographer: Lantz Martin

    Image: US rapper and record producer Ken Carson poses in profile for a black and white shot

    Jordan Curtis Hughes Matty Healy from The 1975 plays a keyboard while surrounded by clutter and musical instruments in what looks like a living room Jordan Curtis Hughes

    Category: Making Music

    Photographer: Jordan Curtis Hughes

    Image: British rock pop band The 1975’s lead singer-songwriter Matty Healy, surrounded by music instruments and snacks

    Jen Amelia Veitch Image of a clubber with long, blonde hair holding a fan and a billiard ball, lying on a billiards tableJen Amelia Veitch

    Category: Underground scenes

    Photographer: Jen Amelia Veitch

    Image: A clubber at Hidden club night in Manchester posing on a billiards table

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  • Total Intravenous Anaesthesia and an Opioid-Sparing Strategy for an Extended Left Hemihepatectomy with Total Caudate Resection, Total Hepatic Vascular Exclusion, and Venovenous Bypass: An Integrative Anaesthesia Approach

    Total Intravenous Anaesthesia and an Opioid-Sparing Strategy for an Extended Left Hemihepatectomy with Total Caudate Resection, Total Hepatic Vascular Exclusion, and Venovenous Bypass: An Integrative Anaesthesia Approach


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  • NTSB describes turbulence that threw passengers around cabin on Delta flight

    NTSB describes turbulence that threw passengers around cabin on Delta flight

    Passengers who weren’t buckled aboard a Delta Air Lines flight to Europe were violently thrown into the ceiling and back down to the floor in July when the plane encountered severe turbulence in a thunderstorm over Wyoming, according to a new report on the incident.

    The National Transportation Safety Board said Tuesday that passengers endured 2.5 minutes of turbulence that caught the pilots by surprise on July 30 even though they had already altered their route to try to avoid the storms. The seat belt sign was off so passengers, flight attendants and drink carts were thrown around the plane.

    The flight took off from Salt Lake City and was bound for Amsterdam, but it diverted to Minneapolis, where 24 people were evaluated by paramedics and 18 were taken to hospitals. Two crew members sustained serious injuries and five sustained minor injuries.

    The preliminary report said during the turbulence the passengers felt a gravitational force up to 1.75 times their body weight.

    “That’s a lot of force. That’s like a muscle man grabbing you by the shoulders and with all of his strength trying to pull you up,” said aviation safety consultant Jeff Guzzetti, who used to investigate crashes for the NTSB and FAA. “If you’re standing and you experience those types of forces, you’re going to be thrown upward into the ceiling and then back down again onto the floor with a lot of force.”

    Guzzetti said that enduring turbulence that lasted that long would seem like “an eternity” for the passengers feeling those forces. The NTSB also said the plane’s wing dipped down as much as 40 degrees at one point, and Guzzetti said that would have alarmed passengers.

    That fits with what passengers described afterward.

    “They hit the ceiling, and then they fell to the ground,” Leann Clement-Nash told ABC News. “And the carts also hit the ceiling and fell to the ground and people were injured. It happened several times, so it was really scary.”

    The report said that the pilot had turned off the seatbelt sign and flight attendants had begun drink service shortly before the plane encountered the turbulence.

    The pilots likely believed they were in the clear after asking air traffic controllers to route them around the storms. But the NTSB charted the plane’s flight path over a radar report from the National Weather Service that showed the plane flew directly into a bright red section of the map showing the worst of the storm.

    Guzzetti said the NTSB will investigate whether the pilots and crew did enough to avoid the storms and whether the pilot made a good judgement in turning off the seatbelt sign.

    Serious injuries from in-flight turbulence are rare, but scientists say they may be becoming more common as climate change alters the jet stream.

    Several turbulence incidents have been reported this year, which only added to the concerns about aviation safety after the worst aviation disaster in years. In January, a midair collision over Washington, D.C., killed 67 people. A plane also flipped over as it crashed in Toronto in March.

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