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  • Elvis Presley wasn’t fond of ‘Burning Love.’ Then it became a hit.

    Elvis Presley wasn’t fond of ‘Burning Love.’ Then it became a hit.

    By all objective measures, Elvis Presley was a hunk, a hunk of burning love. But he clearly wasn’t feeling it when he heard a demo of “Burning Love” at RCA Hollywood Studios in March 1972.

    The song, a slightly shocking blend of the spiritual and sexual, seemed like a hit to those in the room, with its reverent, raunchy intro:

    Lord Almighty, I feel my temperature rising, mmm.Higher, higher, it’s burning through to my soul.Girl, girl, girl, girl, you’re gonna set me on fire.My brain is flaming, I don’t know which way to go, yeah.

    “Elvis didn’t hate the song, he just wasn’t in the mood for it,” Jerry Schilling, Elvis’ longtime friend who attended the session, tells USA TODAY.

    In the end, Presley reluctantly recorded the gospel-rock track, giving it his high-octane all: “He knew everyone felt that he should do it, he was a reasonable man,” Schilling says. It became Elvis’ final Top 10 hit, peaking at No. 2 on the Billboard Hot 100 that fall.

    “I don’t think Elvis was ever too thrilled about singing lyrics like ‘Flames are now licking my body,’ but he loved having a hit record,” Schilling, 83, writes in the introduction to “Sunset Boulevard,” a new five-disc, 89-track collection that spans Presley’s Los Angeles studio sessions from 1970 to 1975. (Schilling can be glimpsed in the set’s archival images: “I’m very proud to be standing behind Elvis on the cover.”)

    The set includes rare alternate takes − half of which have never been released in the U.S. − rehearsals for his Las Vegas residency, and new stripped-down mixes of classic Elvis cuts, including “For the Good Times,” “Tiger Man,” “T-R-O-U-B-L-E,” “Green, Green Grass of Home,” “Pieces of My Life,” “Memories” and “Softly As I Leave You.”

    “I’m kind of a purist, you know: Don’t mess with Michelangelo’s paintings or change the clouds. Don’t mess with the artist,” says Schilling, talking from his home in California, which Elvis gifted him in 1974. “There’s a tremendous responsibility. When the big questions come up, I go, what would I do if Elvis was sitting next to me? That’s how I judge it. I know my friend.”

    The singer never shied away from the provocation of songs like “Burning Love,” Schilling adds. But in the early ‘70s, as Elvis privately struggled with his disintegrating marriage to Priscilla Presley, he gravitated toward expressions of heartbreak and regret such as the autobiographical “Separate Ways” and “Always on My Mind” (both included in the set).

    Over time, he came to embrace the lusty song as part of his live repertoire, breaking it out months later for an epic “Aloha From Hawaii” performance.

    “There’s a part of Elvis that wanted to be sexy,” Schilling says. “And there’s a part of him that wanted to be a great gospel singer.”

    In “Burning Love,” he got to be both.

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  • Independent disciplinary process update: Dan Sheehan (British and Irish Lions) – World Rugby

    Independent disciplinary process update: Dan Sheehan (British and Irish Lions) – World Rugby

    1. Independent disciplinary process update: Dan Sheehan (British and Irish Lions)  World Rugby
    2. Australia’s Tom Lynagh ruled out of third Test against Lions after brutal elbow  The Independent
    3. Independent Disciplinary Update: Dan Sheehan (British & Irish Lions)  World Rugby
    4. Lions hooker Sheehan cited for dangerous Lynagh cleanout  RUGBY.com.au
    5. ‘Just absurd’: Wallabies fans fume over missed Tom Lynagh act as TMO drama baffles  Yahoo Home

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  • Opposition alliance urges CJP to act on Rs300bn sugar scandal

    Opposition alliance urges CJP to act on Rs300bn sugar scandal

    The Tehreek Tahaffuz-e-Ain has written to Chief Justice of Pakistan (CJP) Yahya Afridi, urging him to take suo motu notice of an alleged sugar industry scandal in which mills reportedly profited by Rs300 billion due to recent price fluctuations.

    In a letter addressed to the CJP, Vice Chairman Mustafa Nawaz Khokhar called for the formation of a commission under Article 184(3) of the Constitution to investigate suspected policy manipulation and regulatory failures.

    Khokhar requested that the issue be urgently referred to a three-member committee or that the letter be treated as a formal petition to initiate judicial proceedings.

    “The future of the country’s economic stability and citizens’ trust in governance hinges on prompt and decisive action,” the letter added.

    It further highlighted that the Public Accounts Committee was informed on Tuesday, July 29, that sugar mills had earned Rs300 billion through recent rate hikes.

    CCP reschedules hearing

    The Competition Commission of Pakistan (CCP) has postponed the hearing of the sugar cartel case after over 70 sugar mills requested a delay, citing the unavailability of legal counsel due to the Supreme Court’s summer recess.

    In a statement issued on Monday, the CCP announced that the hearing will now take place from September 22 to 25. The decision follows multiple adjournment pleas submitted by sugar mills.

    More than 50 mills have also filed appeals in the Supreme Court challenging the tribunal’s decision directing the CCP to rehear the case.

    The commission clarified that the hearing has been deferred once to fulfil the requirements of a fair trial. However, it emphasised that no further delay or adjournment would be granted.

    The CCP stated that the case proceedings will be conducted daily.

    Read: CCP to hear sugar pricing case today

    Earlier in May, the Competition Appellate Tribunal had returned the case to the CCP for rehearing after announcing its verdict on the appeals filed by the sugar mills and the association against a Rs44b fine.

    The tribunal instructed that the case be reheard under the supervision of the CCP chairperson or any other member who was not previously involved in the hearings.

    The tribunal also ordered the commission to complete the rehearing and issue a verdict within 90 days.

    In 2021, the CCP imposed a Rs44 billion fine on the PSMA and its member mills for forming a cartel to fix sugar prices and engaging in other anti-competitive practices.

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  • James Norton’s King & Conqueror Set For Prime Video & HBO Max

    James Norton’s King & Conqueror Set For Prime Video & HBO Max

    EXCLUSIVE: James Norton and Nikolaj Coster-Waldau‘s King & Conqueror will play on Prime Video in the U.S. and HBO Max in a slew of territories after Paramount Global sealed a raft of deals for the soon-to-launch historical epic.

    The drama stars Norton as Harold, Earl of Wessex, opposite Coster-Waldau as William, Duke of Normandy, two men destined to clash at the Battle of Hastings. Emily Beecham plays Edith Swan-neck and Clémence Poésy stars as Matilda, their respective wives. The drama tells the story of the people, dynasties and events that went on to shape history.

    The series is produced by Rabbit Track Pictures, the label that Norton runs with Kitty Kaletsky, alongside The Development Partnership, Shepherd Content, RVK Studios and CBS Studios, in association with the BBC, which has the UK rights and launches the show later this month. The first trailer dropped last week.

    Paramount Global Content Distribution is across sales and has racked up deals spanning over 100 territories. Prime Video has taken it for the U.S. and HBO Max will show the 1066 drama in the Nordics, Iberia, Southeast Asia, the Netherlands, Hong Kong, and Taiwan.

    PGCD held a packed buyers-only screening for King & Conqueror – the opening episode of which is directed by Baltasar Kormákur – at the London Screenings in February.

    It clearly struck a chord with the assembled acquisitions folk. SBS has acquired it for Australia and JioHotstar for India. It has also sold to buyers including Showcase and StackTV (Canada), M-Net (Africa), Streamz and Be TV (Belgium), Cosmote TV (Greece), Yes and Hot (Israel), Sky NZ (New Zealand), and LRT (Lithuania).

    The deals come ahead of a glitzy London premiere for the series, next week.

    King & Conqueror is a sweeping, cinematic drama with global appeal, and we’re thrilled to see such strong demand from leading platforms around the world,” says Lisa Kramer, President of International Content Licensing at PGCD. “Compelling storytelling, exceptional cast, and bold creative vision make it a standout series that resonates across markets and cultures.”

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  • FAQs and how to watch the action live

    FAQs and how to watch the action live

    How and where to watch The World Games 2025 Chengdu live?

    Select action from The World Games 2025 Chengdu will be available to stream live on Olympic Channel via Olympics.com with territorial restrictions in place.

    The sports of Cheerleading, Flying Disc, Powerlifting, Flag Football, Lacrosse, Squash, Softball (Finals), Gymnastics (including Parkour), Roller Sports, Breaking (Finals) and Sport Climbing will be available to watch live in Brazil, France, UK, Germany, Spain, Republic of Korea, Indonesia, Egypt, and South Africa.

    In Japan, the following sports will be streaming: Cheerleading, Flying Disc, Powerlifting, Squash, Gymnastics (including Parkour), Roller Sports, Breaking (Finals) and Sport Climbing.

    World Games action will also be available to watch live in India, with restrictions still to be announced.

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  • 4 Taylor Swift-Inspired Business Tips CEOs Can Take From the Billionaire

    4 Taylor Swift-Inspired Business Tips CEOs Can Take From the Billionaire

    Taylor Swift is not only a beloved musical artist with an ever-growing catalogue of innately singable songs; the billionaire pop star is increasingly the preeminent example of a powerhouse business strategist forging a new path for those who seek to steal market share and run the game their way.

    The mega star’s business acumen is the subject of Sinéad O’Sullivan’s forthcoming book, “Good Ideas and Power Moves: Ten Lessons for Success from Taylor Swift.” O’Sullivan, a defense economist, investor, and writer, used her own business expertise to analyze Swift’s career.

    As O’Sullivan navigated her own high-powered career with stints at the Department of Defense and NASA, the Harvard Business School alum and self-proclaimed “massive Swiftie” told Business Insider that she couldn’t get Swift’s singular road map out of her head.

    “Anytime I thought about her, I thought about how what we’re teaching at business school no longer resonates with what she is doing,” O’Sullivan said in a June interview. “I started to think less about what Warren Buffett would do, and more about what Taylor would do.”

    “Good Ideas and Power Moves” is the culmination of more than a decade’s worth of O’Sullivan’s obsession with Swift, she told Business Insider. “It was all in my head already, so the book only took me six weeks to write.” In it, O’Sullivan unpacks 10 of Swift’s unique power moves that anyone from Fortune 500 CEOs to small-time retailers can emulate to build their base and top the charts.

    Here is a sample of some of the tips O’Sullivan explores in her book, which is out September 9.

    Build power laterally — not from the top down

    Much of Swift’s massive cultural power comes from her fiercely loyal and ever-expanding fan base. The Swifties, as her fans are known, have played a major role in the singer’s ability to maintain relevance for more than a decade amid a rapidly shifting music industry. From shelling out thousands for Eras Tour tickets to exclusively listening to the singer’s re-recordings (and shaming anyone who refuses to do the same), Swifties are among the most zealous fans operating today.

    Unlike traditional business structures, where power and control flow from executives at the top down to employees at the bottom, Swift’s power moves laterally, O’Sullivan said.

    The singer has emphasized her own relatability and nurtured her relationship with her dedicated devotees to create a fanbase that feels as though Swift is one of them, the author told Business Insider.

    “She has enabled an entire group of people not by being above them, but by being one of them,” O’Sullivan said. “A lot of the time, she’s not even in the room, and her fans move without her.”

    When one of Swift’s Eras Tour shows was canceled in Vienna in August 2024, her fans organized impromptu gatherings where they sang her songs, exchanged friendship bracelets, and recreated the concert experience — all without any guidance or direction from the singer herself.

    Wielding her power horizontally has allowed Swift to scale very quickly, O’Sullivan said, citing the singer’s “peer-to-peer currency.”

    “She no longer even needs to be present for her power to increase,” O’Sullivan said. “Her fans feel like she is always there, but what they actually are experiencing is having other Swifties around.”

    Be antifragile

    Swift has managed to catapult herself to unmatched levels of power amid a particularly unpredictable moment in business.

    “We live in a weird time. Everything feels like it no longer fits our models,” O’Sullivan said. “The rules have kind of stopped following the traditional, long-held patterns.”

    Uncertain times, however, present a unique opportunity for those who have figured out how to get stronger, not weaker, in moments of adversity. After nearly two decades in the music industry, Swift has mastered antifragility, jumping in popularity and sales at moments where other singers have fallen, O’Sullivan said.

    Take the pandemic, for example. COVID lockdowns curtailed artists’ abilities to do their jobs as tours were put on hold, studios shut down, and promotion took a back seat.

    But where others saw a closed door, Swift saw an opportunity. With people sitting at home under lockdown, the singer understood people needed more content, not less. And because she owns her entire supply chain — an in-house recording studio, strong relationships with other musicians, and the ability to go direct-to-consumer — she was able to give the people what they needed during a difficult time. In July 2020, at the height of the pandemic, the singer released “folklore,” which became the best-selling album of the year.

    “When others find difficulties in the system breaking down, that’s when Swift is able to get in and win big,” O’Sullivan said. “Every time something ‘bad’ happens to her, she is actually able to use it to make big leaps in her career and steal market share.”

    Negotiate with authenticity

    From the moment she burst on the scene at 16 years old, Swift’s superpower has always been her authenticity, O’Sullivan said.

    “In the world of business and finance, it’s uncommon to have unwavering beliefs and such a strong sense of self,” the author said. “People tend to shift quite quickly depending on the markets or who is in power.”

    Not Swift, according to O’Sullivan.

    Sure, the singer initially gained popularity by singing about romance and relationships, but as she moved into her older teens — a time when the music industry typically forces female performers into sex-centered stereotypical roles — Swift removed herself from that equation and doubled down on her real self.

    Authenticity is especially important for Swift because the product she’s selling is herself, O’Sullivan said; any hint of phoniness or fraud in the superstar’s marketing would be immediately obvious to her dedicated fans who feel like they personally know the singer thanks to her confessional lyrics.

    Swift’s reverence for her own deep feelings and emotionality — traits that are traditionally scorned in the male-dominated business world — have actually given her significant leverage among her primarily female fan base, O’Sullivan said.

    “She’s just a great example of doing things in a totally different way,” the author said.

    Don’t eat the marshmallow

    That Swift’s profile is as massive as it is, nearly two decades into her career, is proof enough that she’s something special, O’Sullivan said. The music industry, like so many others operating under capitalism’s quarter-to-quarter earnings system, churns out performers and products at a rate meant to capitalize on novelty and the next big thing.

    Swift’s long-game mindset has garnered her longevity and legacy in a world where so many others have achieved only immediate validation, O’Sullivan said.

    “Good things take time and patience,” she said. “Real success often requires you to forgo early wins.”

    Instead of chowing down on the proverbial marshmallow as soon as it’s been roasted, Swift has built an empire on taking her time to create the perfect s’more.

    “If you’re a CEO, you probably feel that pressure every minute,” O’Sullivan said. “But it’s about having a long-term strategy so you don’t have to just take the next thing coming.”


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  • New ancient marine reptile species discovered in Germany’s famous Jurassic fossil beds

    New ancient marine reptile species discovered in Germany’s famous Jurassic fossil beds

    image: 

    Plesionectes longicollum 


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    Credit: Credit Artist: Peter Nickolaus

    Paleontologists have identified a new species of ancient marine reptile from Germany’s world-renowned Posidonia Shale fossil beds, expanding our understanding of prehistoric ocean ecosystems that existed nearly 183 million years ago.

    The newly classified species, named Plesionectes longicollum (“long-necked near-swimmer”), represents a previously unknown type of plesiosauroid—the group of long-necked marine reptiles that inhabited Earth’s oceans during the age of dinosaurs. The specimen is a nearly complete skeleton that even preserves remnants of fossilised soft tissue. It was originally excavated in 1978 from a quarry in Holzmaden, Southwest Germany, but its unique anatomical features have only now been fully recognized through comprehensive scientific analysis.

    “This specimen has been in collections for decades, but previous studies never fully explored its distinctive anatomy,” said Sven Sachs of the Naturkunde-Museum Bielefeld, the study’s lead author. “Our detailed examination revealed an unusual combination of skeletal features that clearly distinguish it from all previously known plesiosaurs.”

    The research, published by Sven Sachs and co-author Dr. Daniel Madzia from the Polish Academy of Sciences, demonstrates that the Posidonia Shale—already famous for its exceptionally preserved fossils—contained even greater marine reptile diversity than previously recognized.

    The Plesionectes specimen is particularly significant as it represents the oldest known plesiosaur from the Holzmaden area. Despite being an immature individual, its distinctive anatomical characteristics were not significantly affected by its developmental stage, warranting classification as an entirely new genus and species.

    “This discovery adds another piece to the puzzle of marine ecosystem evolution during a critical time in Earth’s history,” explained Dr. Madzia. “The early Toarcian period when this animal lived was marked by significant environmental changes, including a major oceanic anoxic event that affected marine life worldwide.”

    The fossil is permanently housed at the Staatliches Museum für Naturkunde Stuttgart (Stuttgart State Museum of Natural History) where it is cataloged as specimen SMNS 51945.

    The Posidonia Shale at Holzmaden has previously yielded five other plesiosaur species, including representatives from all three major plesiosaur lineages. This new addition further cements the formation’s status as one of the world’s most important windows into Jurassic marine life.

    Read the full article in PeerJ Life & Environment https://peerj.com/articles/19665/ (please note this link will only work from 4th August.)

    Watch a video interview with author https://youtu.be/C3J0YAk4WEc


    Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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  • What’s Inside the Tiny Miracle Food Pouches That Can Save the Lives of Starving Gazans

    What’s Inside the Tiny Miracle Food Pouches That Can Save the Lives of Starving Gazans

    Take a peanut-based paste packed with 500 calories and nearly 13 grams of protein. Store it in a 92-gram foil pouch, so it can be easily sucked by starving infants on the front line. No water or refrigeration is required, meaning it can be distributed in drought-hit areas and stored at ambient temperature for up to two years. Just a couple of daily sachets can lead to a 10 percent weight gain over six weeks, sustaining recovery from severe acute malnutrition for less than $60 per child. Saving a life, it turns out, literally costs peanuts: just 71 cents a serving.

    This life-saving mixture is Plumpy’Nut. Developed by Normandy-based manufacturer Nutriset in 1996 by French paediatrician André Briend, it was the first ready-to-use therapeutic food (RUTF): energy-dense pastes that have boosted survival rates of severe acute malnutrition in children from less than 25 per cent to around 90 percent.

    The paste has saved tens of millions of lives. “It’s incredibly effective emergency food,” says medical doctor Steve Collins, founder of advocacy group Valid Nutrition. “RUTF contains all the essential nutrients required for someone to recover from severe acute malnutrition. They’re easy to transport, extremely energy dense, and don’t require a cold supply chain or clean water to work.”

    While Nutriset’s product was the first RUTF to be developed, it is not the only brand in this important field. Mana, for example, is an American-made RUTF produced in Fitzgerald, Georgia. The company states it can make 500,000 pounds of product per day—enough to fill four shipping containers, and feed 10 million children per year.

    Before Plumpy’Nut, cases of severe acute malnutrition—primarily occurring among children under 5 years old, diagnosed by very low weight-for-height scores and arm circumference—needed round-the-clock care at therapeutic feeding centres. Nurses at these makeshift hospitals in often remote areas would feed infants F100, a high-energy milk powder also made by Nutriset. Bacteria was often rife. “There was always a risk that water was contaminated and carried disease,” says Collins. It’s one of the reasons why mortality rates for in-patient care lurked at around 20 percent.

    Over half of Plumpy’Nut is made from peanut paste and vegetable oils. The nutty primary base contains fat-soluble nutrients, as well as protein, energy, and fatty acids that spark recovery. Nearly a quarter is skimmed milk powder, containing dairy protein and essential amino acids, the building blocks of protein. Another quarter is reserved for sugar—masking the taste of the added micronutrients: potassium, magnesium, calcium, iron, zinc, iodine, copper, selenium, and vitamins A, D, E, B complex, C, and K.

    The apocryphal story is that Briend’s idea for the marvel that is Plumpy’Nut came from a jar of Nutella. In reality, it came from firsthand experience on the front line in the Sahel: The water-based solution wasn’t working—infants were still dying. Working with Nutriset founder Michel Lescanne, his idea was to add F100 to a spread of peanuts (a common crop in areas of malnutrition and a natural protein-rich source) with oil and sugar.

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  • How AJ Wolfe Gets It Done

    How AJ Wolfe Gets It Done

    Photo-Illustration: by The Cut; Photo: AJ Wolfe/Yulia Reznikov

    If Disney adults were to have their own Magic Kingdom, AJ Wolfe would be their queen. Back in 2009, Wolfe launched the Disney Food Blog, a site focused on reviewing the theme parks’ snacks and meals, while working as a grant writer. This was before the influencer era, when Disney didn’t publish restaurant menus online and many visitors would book months in advance without knowing what they would eat at the parks. In the years since, Wolfe has expanded the blog into a content empire, managing 50 employees who cover every new merch drop (like the new Lilo and Stitch popcorn bucket) and snack item (such as thisS’mores Cake at the Magic Kingdom) across multiple platforms with millions of followers. She’s turned her obsession with Disney and travel into a lucrative career path: “I’m always thinking, How can I make other people’s lives better, and how can I do that in a new way they’ve never seen before?” she says.

    She also has a new book, Disney Adults: Exploring (and Falling in Love With) a Magical Subculture, hitting shelves on August 5. It’s an in-depth exploration of one of the internet’s most reviled fandoms that explains just how the multibillion-dollar conglomerate has managed to build such a devoted following, and why fans from all over the globe spend tens of thousands of dollars to return to its theme parks over and over. Wolfe lives in Dallas with her husband and 11-year-old son; here’s how she gets it done.

    On her typical workday: 
    When my kid’s in school, I get up at 6 a.m. I am usually in meetings all day from nine to five, and then after five is when I actually get to do my work. During the day, I’m managing people and relationships and contacts. From five on is when I get to do the creative stuff, like figuring out: What’s the new trend that’s about to take over? How are we going to restructure this particular part of the company? How will we connect with this partner? And then I’m basically working until 1 a.m.

    On how her job has changed over time: 
    Right when I first started, it was me covering everything. I was at the parks twice a month, going to every single booth, buying every single food item. Now, I’ve hired a team who is in the parks every day. So when I’m there, which is about every four months, I’m going to meetings and managing partnerships and relationships from nine to five. After that, I’m trying not just food, but also new rides, restaurants, and tips and tricks that we’re testing out.

    On managing stress as an entrepreneur: 
    You don’t have a “do not disturb” button if you are running a company like this. I have high anxiety, and I am stressed all the time. Being in this business, I see it as a growth opportunity to figure out how to deal with stress and balance my life while still kicking ass. I’m an introvert, and I have to interact with people a lot in this business, which makes me uncomfortable. I’m actively trying to make myself better by doing things that make me uncomfortable.

    On dealing with challenges: 
    We rely on being in the Disney parks to create content, and Disneyland was shut down for over a year, while Disney World was shut down for months, during COVID. We were like, “What the hell do we talk about now?” I vividly remember sitting there talking to my team and figuring out, “Okay, what are we going to write about that’s going to be useful to people while they’re stuck at home? ‘Here’s some crafts you can do with all of the toilet paper you stockpiled,’ or ‘Here’s how you can bake Disney desserts at home’?” We got countless emails from readers and viewers and followers who were like, “Thank you so much for giving me a Disney space, even though we’re in the midst of this turmoil and upheaval.” We didn’t lay anybody off. We paid everybody, even the people whose entire job is going into the parks. We pivoted so that we could continue to add value for the people who followed us, and it was incredibly successful.

    On her biggest win: 
    Our company has been successful in increments. When Disney first recognized us as existing, when we first got invited to a media event, when I had a New York Times feature written about me, those were wins. I can’t point to any one thing that was pivotal, and I think that’s good advice for entrepreneurs: There may not be a big, dramatic success story. It may just be you doing things well and trying to create value for the people that follow you, and you will consistently gain.

    On the responsibility of having a big audience: 
    We know that as soon as we write about something, everybody might do it and it might ruin this little special thing. Back in 2009, I wrote about how I found a Coke machine that was way cheaper than any other Coke machine; I could never write that today, because Disney would give you pushback and because thousands of people would descend upon that Coke machine. Right now, we’re getting a ton of traffic for an article we wrote about a dress at Walmart that one of my team members bought, and it’s packable and really good for a Disney park. That dress is sold out on Walmart. We have a significant impact. We have a big audience, and we don’t want to write about something so that it affects cast members [Disney employees and staff] in a negative way.

    On the people who help her get it done: 
    I have a housekeeper who cleans my house, and she’s been with us since my kid was a baby. I have a personal assistant who helps me manage my household, who goes through and files my mail and makes sure that my HOA dues are paid and does all of that stuff. Day-to-day management of the household is not something I’ve ever been good at. I’m outsourcing my weaknesses so that I have more time to sit here and go, “Wait a minute, what’s the best Dole Whip?”

    On what she’s learned as a manager: 
    We’re an entirely virtual company, so we’re not in an office and we have people all over the world. I’ve had several situations where things were happening in DMs where someone was being rude to others, and I just didn’t know. No one said anything. Eventually, that person quit, and everything got better. If you as a manager are seeing that people seem like wounded animals, somebody’s doing something that’s making them feel that way, and it’s your job to go figure it out. Which I didn’t — I totally screwed up. That was a learning experience: If it feels like there’s an undercurrent of poison, go figure out what that toxicity is, and get rid of that person.

    On winding down after a long day: 
    I’ve been watching a lot of Travel Man, which is a British show hosted by Richard Ayoade. He takes a bunch of other comedians for a two-day trip to a different city. You will often find me consuming content that has to do with travel or history, usually British or European-based.

    On the advice she wishes she’d gotten when she started out: 
    Influencers want the spotlight; they want to be important. But you’re not important. What’s important is how you can affect other people and make their lives better. So start thinking about how what you think can affect other people. Do that first, and you will find success.

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  • New drug combo outperforms Tamiflu in fighting deadliest flu strains

    New drug combo outperforms Tamiflu in fighting deadliest flu strains

    A surprising new drug combo—including a compound found in chocolate—has outperformed Tamiflu in fighting the flu, according to a study published in PNAS. The mix of Theobromine and Arainosine proved far more effective against a range of flu strains, including drug-resistant versions of bird and swine flu. By targeting a key viral weakness, this breakthrough could lead to stronger, longer-lasting treatments—not just for the flu, but potentially for other viruses as well.

    In a potential game-changer for how we treat the flu, scientists have unveiled a new drug pairing that outperforms Tamiflu—the most widely used anti-influenza medication—against even the deadliest flu strains, including bird(avian) and swine flu.

    The surprising duo? One of them is Theobromine, a compound found in chocolate.

    In a study recently published in PNAS (Proceedings of the National Academy of Sciences), researchers at the Hebrew University of Jerusalem, led by Prof. Isaiah (Shy) Arkin, have developed a novel combination therapy that targets a key weakness in the influenza virus: its ion channel, a microscopic gate the virus uses to replicate and spread. By blocking this gate, the team effectively cut off the virus’s ability to survive.

    Their study, conducted at Israel’s new Barry Skolnick Biosafety Level 3 facility, tested this combo—Theobromine and a lesser-known compound called Arainosine—against a broad range of flu viruses. In both cell cultures and animal trials, the treatment dramatically outperformed Oseltamivir (Tamiflu), especially against drug-resistant strains.

    “We’re not just offering a better flu drug,” said Prof. Arkin. “We’re introducing a new way to target viruses—one that may help us prepare for future pandemics.”

    Why it matters

    The stakes are high: Influenza continues to sweep the globe each year, with unpredictable mutations that challenge vaccines and existing drugs. In the U.S. alone, seasonal flu costs an estimated $87 billion annually in healthcare and lost productivity. Past pandemics—like the 2009 swine flu—have inflicted even deeper global costs, and the cost of future pandemics was estimated to rise even further up to $4.4 trillion.

    Meanwhile, outbreaks of avian flu have devastated poultry industries and sparked fears of cross-species transmission to humans. Just one recent outbreak in the U.S. led to the loss of 40 million birds and billions in economic damage.

    Current flu treatments, like Tamiflu, are losing ground as the virus adapts. Most drugs in use target a viral protein that mutates frequently, rendering treatments less effective over time. That’s where Arkin’s team saw an opening.

    A new strategy for old viruses

    Instead of fighting the virus head-on with traditional antivirals, the researchers zeroed in on the M2 ion channel—a crucial viral feature that helps the virus replicate. Past efforts to block this channel have largely failed due to drug resistance. But the new Theobromine-Arainosine combo sidesteps this resistance, even neutralizing hard-to-treat strains.

    The team discovered the combo by scanning a library of repurposed compounds—many originally developed for other diseases—and testing their effects on both drug-sensitive and drug-resistant versions of the virus.

    Broader implications

    The implications extend beyond influenza. Because many viruses—including coronaviruses and others—also rely on ion channels, this new approach could form the basis of future antiviral strategies.

    The next steps include human clinical trials, but the early results offer hope not just for a better flu treatment, but for a smarter way to fight viral disease in general. ViroBlock, a startup company emanating from the Hebrew University, has been entrusted to develop the discoveries to reach the public.

     

    Source:

    Hebrew University of Jerusalem

    Journal reference:

    Lahiri, H., et al. (2025). A bacteria-based search for drugs against avian and swine flu yields a potent and resistance-resilient channel blocker. Proceedings of the National Academy of Sciences. doi.org/10.1073/pnas.2502240122.

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