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  • Implementing an integrated approach to tuberculosis and lung health

    The World Health Organization (WHO) Global Programme on Tuberculosis & Lung Health is seeking examples of case studies and promising practices that illustrate how integrated approaches to tuberculosis (TB) and lung health have been applied in different country contexts. The call aims to capture efforts that bring together TB prevention, diagnosis, care, and management with broader lung health interventions, including those addressing shared risk factors, co-prevention, and co-morbidity.

    Submissions will be used to inform forthcoming WHO guidance on integrated approaches to TB and lung health. Selected cases may also be featured in technical products or compendia and used to support knowledge exchange, operational learning, and future technical assistance. Contributors whose submissions are included will be duly acknowledged.

    Background to this call

    The burden of tuberculosis and other lung conditions remains substantial and increasingly interconnected. People affected by or at risk of TB often experience or are vulnerable to a range of acute and chronic respiratory conditions, including asthma, chronic obstructive pulmonary disease, pneumonia, and post-TB lung disease. Despite this, health services may often operate without coordination, resulting in fragmented care, inefficiencies, and missed opportunities to improve health outcomes.

    The WHO 2025 policy brief on integrated TB and lung health calls for a syndromic, people-centred approach that reflects the overlapping epidemiology and clinical presentation of respiratory conditions. Integrated models of care can strengthen early detection, improve quality of service delivery, optimise use of health system resources, and improve patient experience. However, implementation remains complex and context-specific, requiring adaptable strategies, intersectoral coordination, and practical know-how informed by country experience.

    Eligibility

    Submissions are invited from national or subnational actors, including Ministries of Health, TB programmes, technical agencies, academic institutions, implementing partners, and civil society organisations. Case studies may describe specific service models, policies, institutional arrangements, coordination mechanisms, or other efforts that demonstrate integration across the care continuum.

    Cases may include, but are not limited to, the following areas:

    • Integrated service delivery models at community or facility level
    • Syndromic management of respiratory symptoms (e.g. chronic cough)
    • Joint screening, diagnostic, or referral pathways
    •  Post-TB rehabilitation and long-term monitoring
    • Policy or governance mechanisms that support alignment across programmes
    • Training and workforce development initiatives
    • Interventions addressing shared risk factors such as air pollution or tobacco use

    Submissions should reflect initiatives implemented in the past decade or currently underway. Cases do not need to represent unqualified successes. Illustrative examples of challenges, adaptations, and learning processes are equally welcome.

    How to submit

    Any eligible stakeholder involved in the case study is invited to complete the submission form. You will be asked to provide basic information about the case, answer several questions intended to capture key elements (e.g. context, enablers and barriers, what was done and by who, outcomes) with short textual summaries, and supply additional materials to enrich and substantiate your description.

    All submissions will be reviewed by WHO for completeness and relevance. Selected cases may be synthesised to inform ongoing guidance development and implementation tools. Contributors will be contacted should further clarification or follow-up be needed.

    Deadline

    Deadline for submission: 31 August 2025

    For questions or further information, please contact us by e-mail:  gonzalezangulol@who.int

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  • Ubisoft partners with Hooded Horse to publish Unfrozen’s Heroes of Might and Magic: Olden Era

    Ubisoft partners with Hooded Horse to publish Unfrozen’s Heroes of Might and Magic: Olden Era

    Manor Lords publisher Hooded Horse has partnered with Ubisoft to publish Heroes of Might and Magic: Olden Era.

    Developed by Unfrozen, the publisher will take over the “day-to-day operations” of the upcoming title.

    As noted by Rock Paper Shotgun, the developer said that Hooded Horse’s involvement “means more marketing support, better visibility, and helps extend our reach to more regions”.

    Ubisoft will remain the owner of the Heroes of Might and Magic franchise.

    “We are thrilled to welcome Hooded Horse aboard to support the next chapter of Heroes Might and Magic,” said Ubisoft chief publishing officer Alain Corre.

    “Their passion for the franchise and strong connection with strategy communities makes them the perfect complement to Unfrozen’s creative talent.”

    Hooded Horse CEO Tim Bender added: “Heroes of Might and Magic is a legendary series, one that has a place in the hearts and childhoods of many gamers. We’re honoured to be teaming up with Ubisoft and Unfrozen on this project.”

    “The entire Unfrozen team is very excited that Hooded Horse is joining the project,” said Unfrozen CEO Denis Fedorov.

    “We firmly believe that their expertise, combined with Ubisoft’s legacy, will allow us to make Heroes of Might and Magic: Olden Era truly successful and introduce the game to even more fans of tactical turn-based strategies from all over the world.”

    The title was revealed in August 2024, though last month the developer announced that early access had been postponed to late 2025.

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  • Nuss and Brasher lead past champions back into Gstaad this week

    Americans Andy Benesh and Miles Partain, who made it to the top of the podium in the Swiss Alps in the 2023 season, will also try to run it back this week. The two have played in just a pair of Beach Pro Tour events so far in 2025, ranking ninth in Brasília and fifth in Ostrava.

    Beach Pro Tour Gstaad Elite – Men’s Entry List

    Norwegians and Americans were part of a training camp ahead of the Gstaad event that also featured Dutch Olympians Stefan Boermans and Yorick De Groot, who triumphed in Switzerland back in 2021. The Europeans already took gold this season, winning in Brasília, but head to Gstaad after leaving the Ostrava Elite way too early and ranking 13th – they were third in Saquarema, their first event in the season.

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  • Nasopharyngeal Staphylococcus aureus Isolation and Bacterial Culture Profiles in COVID-19 Patients: A Comparative Study Based on Lung Involvement

    Nasopharyngeal Staphylococcus aureus Isolation and Bacterial Culture Profiles in COVID-19 Patients: A Comparative Study Based on Lung Involvement


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  • AliExpress Sellers Block Pakistan After Customs Bans Cheap Shipping Methods – ProPakistani

    1. AliExpress Sellers Block Pakistan After Customs Bans Cheap Shipping Methods  ProPakistani
    2. Pakistan’s e-commerce sector faces operational costs surge amid new taxes  Business Recorder
    3. Courier Companies Announce Increase in Delivery Charges After New Taxes  ProPakistani
    4. AliExpress Sellers Block Pakistan After Shipping Ban  Bloom Pakistan
    5. LCCI demands withdrawal of raise in withholding tax on logistic services  nation.com.pk

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  • Tryptase Ratio May Improve Anaphylaxis Diagnosis in Children

    Tryptase Ratio May Improve Anaphylaxis Diagnosis in Children

    TOPLINE:

    In a decade-long study, a ratio of serum acute tryptase to serum baseline tryptase above 1.74 showed superior diagnostic performance compared with the current consensus formula, which requires serum acute tryptase to be greater than a personalized cutoff value. The ratio correctly identified more than two thirds of true cases while ruling out the majority of false cases in children with suspected anaphylaxis.

    METHODOLOGY:

    • Researchers reviewed medical records of 315 children (median age, 7.8 years; 56.2% boys) admitted to the emergency department with suspected anaphylaxis from January 2011 to December 2020 to assess the diagnostic performance of serum tryptase measurements.
    • The diagnosis of anaphylaxis was confirmed when children showed at least one extracutaneous systemic symptom and had evidence of systemic mast cell activation or allergic sensitization to a trigger allergen.
    • Those with a confirmed diagnosis constituted the anaphylaxis group (n = 175), while the remaining served as the control group (n = 142).
    • Researchers compared the diagnostic performance of the consensus formula with that of five alternative tryptase interpretation algorithms.

    TAKEAWAY:

    • Food allergens triggered 82% of anaphylaxis reactions, with legumes, seeds, and nuts being the triggers in 36% of cases, followed by cow’s milk proteins in 28% of cases.
    • Epinephrine was administered in 96 children with suspected anaphylaxis (30.3%), including 14 children who were initially misdiagnosed as having anaphylaxis due to cardiovascular involvement and a credible history of allergen exposure.
    • The ratio of serum acute tryptase to serum baseline tryptase showed optimal diagnostic performance, with an area under the curve of 0.84, sensitivity of 66.7%, and specificity of 90% at a threshold of 1.74 — outperforming the current consensus formula, which has a sensitivity of 62.2% and specificity of 80%.

    IN PRACTICE:

    “Our study underlines the need for better implementation of both sAT [serum acute tryptase] and sBT [serum baseline tryptase] measurements at adequate sampling times in pediatric EDs [emergency departments] and contributes to the ongoing debate on the optimal interpretation of pediatric dynamic tryptase,” the authors wrote.

    SOURCE:

    Moïse Michel, PhD, with the Nîmes University Hospital, Nîmes, France, was the corresponding author of the study, which was published online on June 24 in the Journal of Allergy and Clinical Immunology: Global.

    LIMITATIONS:

    This study was limited by its retrospective design and the absence of grade 4 anaphylaxis cases in the cohort, limiting the evaluation of tryptase measurement performance.

    DISCLOSURES:

    This study did not receive any specific funding. One author reported receiving speaker or consultancy fees from various pharmaceutical manufacturers.

    This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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  • Pakistan to lock horns with India on THIS date in Asia Cup 2025: reports

    Pakistan to lock horns with India on THIS date in Asia Cup 2025: reports

    The highly anticipated India-Pakistan showdown in the ACC Asia Cup 2025 is likely to take place on September 7 in Dubai, with Indian media on Wednesday revealing tentative dates and venue details for the tournament.

    Despite India being the official hosts, the tournament is expected to be shifted to the United Arab Emirates (UAE) due to ongoing political tensions between the two arch-rivals.

    Reports suggest that the Asia Cup 2025 is likely to begin around September 4 or 5, with the final pencilled in for September 21.

    The recurring deadlock between the BCCI and PCB has led to the “fusion formula,” under which both boards reportedly agreed not to visit each other’s home soil for multi-nation events for the next three years.

    Instead, their matches would be staged at neutral venues. That’s why the 17th edition of the continental event will see the arch-rivals clash in Dubai.

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    It’s worth noting that the Asia Cup 2025 will be played in the T20 format and is expected to see India and Pakistan face off at least twice, first in the group stage, and potentially again in the Super Four round, depending on results.

    Six teams will participate in the tournament: India, Pakistan, Sri Lanka, Bangladesh, Afghanistan, and the UAE. The structure will follow the traditional format of a group stage leading into the Super Four, similar to previous editions.

    An official announcement from the Asian Cricket Council (ACC) regarding the final schedule is expected in the second week of July.

    Meanwhile, promotions are already in full swing, with teasers airing on Indian television and circulating across digital platforms.

    It is worth noting that India are the defending champions, having crushed Sri Lanka by 10 wickets in the ODI-format final of the previous edition.

    READ: Shubman Gill drops major hint on India Playing XI for second Test

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  • Benoy celebrates the opening of Resorts World Sentosa’s WEAVE

    Benoy celebrates the opening of Resorts World Sentosa’s WEAVE

    WEAVE: biophilic, experience-led destination

    Benoy celebrates the opening of WEAVE at Resorts World Sentosa (RWS) — a bold new lifestyle destination that reimagines the guest experience through biophilic architecture, sensory immersion and sustainable design.

    Designed by Benoy, WEAVE sets a new benchmark for tropical, experience-led architecture in Singapore, a design-forward hub where architecture, nature and community seamlessly converge.


    A living landscape inspired by nature

    Spanning over 20,000 sqm across three interconnected levels, WEAVE blends lush greenery, organic forms and nature-integrated retail into a living environment that transforms throughout the day. Its architecture draws from the island’s natural topography and cultural richness, inviting guests on a journey that is both restorative and inspiring.

    Azaria Lee stated, WEAVE was envisioned as a living, breathing sanctuary, an architecture of movement, light and landscape. We sought to dissolve boundaries between indoor and outdoor, inviting guests to slow down, explore and reconnect with nature through spatial moments that surprise, shelter and inspire.”


    A rainforest-inspired experience

    Guided by a rainforest-inspired spatial concept, WEAVE unfolds from cool, shaded botanical valleys at the lower levels to vibrant floral terraces above. Natural textures, asymmetrical façades and open-air walkways foster a sense of fluidity and calm, while encouraging moments of community, rest and discovery.


    Greening the guest experience

    Sustainability is integrated in every level throughout WEAVE’s design, from ETFE canopies that reduce solar heat gain by up to 80%, to passive cooling, green walls, rainwater harvesting and recyclable structural materials. Together, these strategies support RWS’s ambition to become a carbon-neutral destination by 2030.

    A gateway between nature, community and commerce

    Strategically positioned within the wider RWS masterplan, WEAVE functions as a dynamic gateway, its central location linking key guest flows across the resort and iconic attractions, while shaping an immersive day-to-night journey through space, nature and experience. 

    Its distinctive Lifestyle Villas feature expansive glass façades and multi-storey decks that open to nature, overlooking lively corridors framed by greenery and seasonal activity. These spaces offer a vibrant platform where community and commerce meet, inviting both local and global brands to thrive.


    Looking ahead

    Benoy congratulates Resorts World Sentosa on the launch of WEAVE and is proud to have shaped its architectural vision. We look forward to seeing how this vibrant, nature-led destination invites people to explore, connect and linger.

    Download the full press release here.

    Image courtesy of Resorts World Sentosa

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  • NASA tests shrinking metals to help it find more exoplanets • The Register

    NASA tests shrinking metals to help it find more exoplanets • The Register

    NASA is exploring the properties of a metal alloy that shrinks as it is heated, as boffins in its Astrophysics Division think it may be needed if the planned Habitable Worlds Observatory (HBO) is to succeed.

    Readers doubtless know that metals expand when heated. As explained in a NASA blog post that’s a problem for space telescopes because if their components warm and expand it can mean that the shape of their mirrors change in ways that make it harder to conduct observations.

    NASA has already developed materials that compensate for those effects and used them in the James Webb Space Telescope and in the Nancy Grace Roman Space Telescope that the aerospace agency intends to launch in 2027.

    The HBO, NASA’s next space ‘scope project after the Nancy Grace Roman, will need even more resilient materials.

    To understand why, the post explains how to observe exoplanets.

    “As light passes through a planet’s atmosphere or is reflected or emitted from a planet’s surface, telescopes can measure the intensity and spectra (i.e., ‘color’) of the light, and can detect various shifts in the light caused by gases in the planetary atmosphere. By analyzing these patterns, scientists can determine the types of gases in the exoplanet’s atmosphere.”

    Observing those shifts is no easy matter, “because the exoplanets appear very near their host stars when we observe them, and the starlight is one billion times brighter than the light from an Earth-size exoplanet.”

    That means the Habitable Worlds Observatory “will need a contrast ratio of one to one billion (1:1,000,000,000).”

    To achieve that contrast ratio, the HBO will need to be 1,000 times more stable than the James Webb telescope.

    Which is why NASA scientists and a company called ALLVAR are investigating a “negative thermal expansion” (NTE) alloy that shrinks when heated.

    According to NASA’s post, “A 1-meter-long piece of this NTE alloy will shrink 0.003 mm for every 1° C increase in temperature.”

    “Because it shrinks when other materials expand, ALLVAR Alloy 30 can be used to strategically compensate for the expansion and contraction of other materials,” NASA’s post states.

    Tests have delivered promising results: ALLVAR apparently built a test mirror mounted on struts of a titanium alloy that expands when heated and struts made with Alloy 30. Both alloys performed as expected, with Alloy 30 offsetting the expansion in the titanium alloy to produce a stable mirror.

    NASA thinks the tests also showed Alloy 30 “enabled enhanced passive thermal switch performance and has been used to remove the detrimental effects of temperature changes on bolted joints and infrared optics.”

    Space boffins are therefore considering how to use Alloy 30 in many other space scenarios.

    You might want to consider using it, too, as NASA wrote “ALLVAR developed washers and spacers are now commercially available to maintain consistent preloads across extreme temperature ranges in both space and terrestrial environments.” ®

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  • Europe heatwave continues and expands eastwards – live updates | World news

    Europe heatwave continues and expands eastwards – live updates | World news

    Key events

    France records second-hottest June since 1900, minister confirms

    France registered its second-warmest June since records began in 1900, the country’s ministry for ecological transition said in comments reported by AFP.

    “June 2025 has become the second hottest June since records began in 1900, behind June 2003,” said France’s minister for ecological transition Agnès Pannier-Runacher.

    People cool off with water from Varsovie fountain by the Eiffel Tower during a heatwave in Paris, France. Photograph: Yoan Valat/EPA

    Spain and Portugal also reported the hottest June temperatures in history.

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