- Official Announcement: Mario Martín realmadrid.com
- Official: Real Madrid midfielder completes loan move to Getafe Yahoo Sports
- Real Madrid announce exit of midfielder on loan deal Football Espana
- Real Madrid midfielder set to join La Liga club on loan, announcement soon Madrid Universal
- Another Real Madrid star’s exit will be made official ‘between today and tomorrow’ Yahoo Sports
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Official Announcement: Mario Martín – realmadrid.com
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Aptar’s First Nasal Pump Made with 52% Bio-Based Material
Aptar Pharma is proud to announce that its Freepod® nasal spray pump – one of the delivery systems for Haleon’s Otrivin® brand – is now made with mass balance bio-based resins. This is the first Aptar delivery system using such materials to be commercialized globally. The use of more sustainable renewable plastic resources is a meaningful measure to help reduce the use of fossil-based materials in healthcare primary packaging.
Reinforcing circularity in pharmaceutical packaging
Aptar Pharma’s Freepod® spray pump used with Haleon’s Otrivin® Nasal Spray is made of 52% ISCC Plus certified bio-based feedstock. The bottle is produced using a mass balance approach equivalent to 100% bio-based content. Together, the pump and bottle components result in an overall circular material content of 60% for the full nasal spray device.
ISCC PLUS certified manufacturing and supply chain
Aptar Pharma is committed to helping its customers meet their sustainability goals, such as reducing the use of fossil-based materials in packaging. The Freepod® nasal spray components are made from bio-based resins derived from renewable feedstocks like bio-waste and residual oils, using an ISCC PLUS-certified mass balance approach. The Aptar Pharma manufacturing site in Mezzovico, Switzerland, is ISCC PLUS certified, ensuring full traceability of materials throughout the manufacturing process and supply chain. ISCC Plus certification also covers all external suppliers – including injection molding providers, service partners, and warehouses – guaranteeing a fully (ISCC) certified supply chain for the Freepod® components.
Partnership for a more sustainable approach
The joint sustainability approach between Haleon (formerly GSK Consumer Healthcare) and Aptar Pharma is built on a long-term partnership spanning over 30 years. This collaboration has led to significant achievements, including the Otrivin® Freepod® winning the World Packaging Award in 2019 for its innovative and sustainable design.
The use of bio-based or renewable feedstocks for the Otrivin® products with Freepod® technology supports Haleon’s goal to reduce virgin petroleum-based plastic use by 10% by 2025** and by a third by 2030, compared to 2022 levels. Aptar Pharma’s Freepod® for Otrivin®, available globally, demonstrates Aptar’s commitment to sustainability and innovation. Looking ahead, this collaboration is anticipated to extend to Otrivin Nasal Mist, Haleon’s latest microdroplet technology, which is being rolled out globally since 2023.
“At Aptar, sustainability is not just a responsibility – it’s a strategic advantage,” commented Gael Touya, President of Aptar Pharma. “The launch of Freepod® Futurity™ reflects our commitment to developing solutions that respond to consumers’ increasing demand for more sustainable healthcare delivery technologies. As a trusted partner to Haleon, we are proud to help drive the success of the Otrivin® brand while enabling a shift away from fossil-based materials in primary packaging. Supporting our partners in reaching their environmental goals reinforces our vision of supporting the healthcare industry, from Formulation to patient.”
With a strong commitment to sustainability, Aptar Pharma continuously strives to reduce its environmental impact and support its partners in achieving their sustainability goals.
*ISCC Plus certified bio-based feedstock, mass balance approach.
**The end point for the goal delivery period is the end of the 2025 calendar year.
Read full Press Release.
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Rugby World Cup Weekly 14
The biggest event in women’s rugby is now just days away, with last year’s finalists among the teams naming their squads as they all begin their respective quests for 2025 glory.
Here is your round-up of all the big announcements plus a whole lot more:
1. Squads taking shape
The squad announcements have been coming thick and fast since USA got the ball rolling earlier this month.
England and New Zealand, finalists at Rugby World Cup 2021, are among those to name their players for this year’s big event, with Natasha “Mo” Hunt returning to the England fold for a crack at the title.
For the Black Ferns, Kelly Brazier will feature in her fourth Rugby World Cup, while Portia Woodman-Wickliffe will take part in her third. On the other end of the experience scale, rising teenage star Braxton Sorensen-McGee is the youngest member of the squad at 18 years of age.
2. Emily Scarratt to make history
Among the names read out for England’s squad announcement was Emily Scarratt, who will make history when she takes the field at Rugby World Cup 2025 by becoming the first England player to compete at five Rugby World Cups.
The playmaker made her tournament debut at Rugby World Cup 2010, and was Player of the Match when England beat Canada in the final of Rugby World Cup 2014. The 35-year-old is the highest ever England Women’s points scorer and has played 118 time for England so far, putting her third in the all-time list behind Rocky Clark and Sarah Hunter.
“More than experience, she understands the legacy of the Red Roses,” England coach John Mitchell said of Scarratt. “She wants to leave the Red Roses in a better place.”
3. ‘Rugby culture truly special’ – Ilona Maher
USA hosted Fiji in a training run at Mount St. Mary’s University on Friday, with the session free and open to the public.
Fiji had been based in the facility all week, and while there was plenty of great rugby on display, there was also time for the teams to mingle and get to know one another ahead of #RWC2025.
USA superstar Ilona Maher posted a video of the two teams singing together in a perfect show of rugby’s shared values.
4. Player watch: Portia Woodman-Wickliffe breaks record
With the news that Portia Woodman-Wickliffe is back for more Rugby World Cup action, it seem appropriate to look back on her stunning performance against USA in May.
The superstar scored a frankly unbelievable seven (yes, seven!) tries during the game, in the process surpassing Vanessa Coutts as the Black Ferns’ all-time leading try scorer.
How lucky we are to have her back in our stadiums and on our screens!
5. Official Fan Zones unveiled
Exciting news for rugby fans as the official Fan Zones for Rugby World Cup 2025 have been unveiled, including one at Piccadilly Gardens in Manchester as well as the iconic Battersea Power Station in London.
Other cities across the UK are also turning up the volume for fans, with vibrant Fan Zones that bring the excitement, passion, and energy of the tournament to life. From iconic landmarks to buzzing community spaces, each host location offers a unique way to soak up the rugby spirit!
6. World Rugby joins UN Women to discuss gender equality
At a special side event of the 2025 United Nations High-Level Political Forum (HLPF) co-hosted by ChildFund Rugby, World Rugby, and UN Women, global leaders from around the world gathered to discuss advancing gender equality and accelerating progress on the UN Sustainable Development Goals.
Held against the backdrop of Beijing+30 and renewed urgency to meet the 2030 Agenda, sport’s role in driving inclusive, evidence-based change at scale was emphasised.
ChildFund Rugby Ambassador Ilona Maher said: “We talk a lot about the power of sport, but it’s time to show what that really means. Sport can change the way girls see themselves and how their communities see them too. When sport is backed by strong partnerships and real investment, it becomes a way to open doors and involve girls in decisions that affect their lives. That’s what this event was about – showing that sport can further gender equality.”
7. Rugby World Cup Replay: Spectacular 2021 final revisited
With England and New Zealand naming their squads for the upcoming tournament, let’s take a look back on the absolute thriller they served up in the 2021 final.
The two best teams in the world went toe to toe as the lead exchanged hands multiple times, with the Black Ferns ultimately holding firm to win their sixth title in front of their jubilant fans.
While New Zealand were the worthy victors on the day, both sides deserve credit for the way they showcased how our game should be played.
8. Team spotlight – Italy
Italy kept up their preparations for Rugby World Cup 2025 by beating Scotland 34-29 at Stadio Luigi Zaffanella on Friday night, with the impressive Alyssa D’Inca scoring a hat-trick of tries.
The Italians beat Wales and Scotland in this year’s Six Nations, and in the first two WXV 2 tournaments they have notched five wins out of six games, including victories over USA and South Africa.
The ever-improving Italians will no doubt be looking to make an immediate impact when their tournament gets underway against France in Exeter on the opening weekend.
9. Mural unveiled in Salford
The excitement for #RWC2025 is rapidly building – mostly evident on the actual buildings themselves in Salford.
Salford Watersports Centre have revealed a mural that includes a tribute to Sale Sharks’ Morwenna Talling, who is part of England’s squad. With all the fever of the Lionesses winning this year’s Euros, there is a real feeling the Red Roses can follow suit and make it a few months to remember for England sports fans!
10. And finally… Rugby Pass to pick Top 50 Players
With so many players at the peak of their powers heading to England for Rugby World Cup 2025, debate around the best and brightest players in the game is hotting up.
Rugby Pass have decided to try settle the debate by engaging experts from around the world to whittle down a long list of supreme talent and come up with the top 50 women’s rugby players.
They’ve considered many factors, from hard-built reputations after years of service, to leadership qualities, consistency and raw ability.
It’s not a simple task and no doubt will spark even more heated conversations online and in rugby clubs and pubs around the world!
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Katie Ledecky goes for 1500 freestyle crown, Kaylee McKeown takes on Regan Smith in 100 backstroke final – live updates
USA legend Katie Ledecky will go for her first gold medal on Day 3 of the swimming competition at the 2025 World Aquatics Championships on Tuesday, 29 July.
Having secured bronze in the women’s 400m freestyle on Day 1, the nine-time Olympic gold medallist is the strong favourite to land the 1500m freestyle title as the Olympic champion and world record holder in the event.
Before that, there will be a mouth-watering showdown in the women’s 100m backstroke final between double Olympic champion Kaylee McKeown of Australia and world record holder Regan Smith of Team USA.
Elsewhere, Romanian star David Popovici will hope to back up his Paris 2024 Olympic gold with a second men’s 200m freestyle world title, while Hubert Kos and Thomas Ceccon lock horns in the men’s 100m backstroke final.
Finally, there will be another clash of the titans in the women’s 100m backstroke final, where US swimmer Kate Douglass takes on former world champion Tang Qianting of the People’s Republic of China.
In this morning’s heats, USA’s Bobby Finke qualified for the men’s 800 freestyle final alongside fellow Olympic gold medallists Lukas Märtens and Daniel Wiffen, the latter still recovering from a recent appendicitis, while reigning Olympic champion Mollie O’Callaghan of Australia booked her place in this evening’s women’s 200 freestyle semis.
The World Aquatics Championships — previously known as the FINA World Championships and often referred to as the World Swimming Championships — have been held since 1973. The Singapore edition marks the 22nd staging of the event.
Follow our live updates across the four finals.
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Sovereign Club seals landmark Pakistan-France partnership
At the prestigious Cercle National des Armées in Paris—France’s historic military command center—a high-level signing ceremony took place, symbolizing a new era of strategic cooperation between France and Pakistan.
The ceremony was attended by Aurélien Lechevallier, Private Secretary to the French Minister of Foreign Affairs, a senior figure deeply embedded within President Emmanuel Macron’s inner circle.
Mr. Hassan Ahmed signed two landmark agreements on behalf of The Sovereign Club:
With Mr. Olivier Chiabodo, CEO of The Explorers, to promote Pakistan’s global image through impactful cultural storytelling and documentary productions.
With Mr. Charles Guépratte, CEO of FEHAP, for the structured training and deployment of Pakistani caregivers to France, executed through BORDERAK, a dedicated platform bridging Pakistan and Europe.
A symbolic exchange of medallions between Mr. Ahmed and Mr. Lechevallier highlighted the mutual respect and strategic depth of this partnership. The selection of Cercle National des Armées as the venue underscores that the initiative is recognized and supported at the highest level of the French Republic.
This landmark event blends diplomacy, culture, and human capital—positioning The Sovereign Club at the forefront of Pakistan’s international engagement with powerful allies across Europe.
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Surprising ally in the fight against schizophrenia: Llamas
Thanks to llama antibodies, French researchers have successfully reduced the symptoms of schizophrenia.
This breakthrough, which involves crossing the brain’s protective barrier, could revolutionize the treatment of mental disorders. According to a new study, llamas may offer a beacon of hope for schizophrenia treatment.
Schizophrenia is a severe brain disorder that causes individuals to perceive reality abnormally. However, this domesticated, woolly animal native to South America might hold the key to helping treat the disease.
This week, French scientists announced they designed a small part of an antibody called a “nanobody” using llama antibodies – proteins that help protect the immune system. This nanobody can activate a neurotransmitter that regulates neural activity in the brain.
Neurotransmitters are chemical molecules that carry messages between nerve cells.
Previously, llama antibodies have been shown to be effective in combating COVID-19 and other SARS-like viruses.
Researchers at the Institute of Functional Genomics (IGF) observed that when this molecule was injected intravenously or intramuscularly, it could cross the blood-brain barrier and reach brain receptors. This barrier is a tightly packed layer of cells that protects the brain from harmful substances.
In two separate tests on mice, scientists found that the nanobodies improved cognitive impairments. A single injection led to noticeable improvements in cognitive functions and these effects lasted for up to a week.
The next step involves clinical trials to determine whether these findings could offer a new approach for treating Schizophrenia in humans.
How does Schizophrenia develop?
Schizophrenia is a chronic disease with no known exact cause. However, the World Health Organization (WHO) suggests that a combination of genetic and environmental factors may contribute to the development of the condition. It is difficult to measure how often Schizophrenia occurs precisely.
Although it can appear at any age, Schizophrenia is typically diagnosed between the ages of 16 and 30. Symptoms vary from person to person.
While there is no definitive cure, Schizophrenia can be managed with antipsychotic medications, therapy and personal coping strategies, according to the National Alliance on Mental Illness (NAMI).
The authors of this study aim to integrate this new nanobody-based method into existing treatment strategies.
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Cola NEXT Sets New Sustainability Benchmark With Eco-friendly Bottle Design
Cola NEXT’s innovative packaging initiative is thoughtfully designed to tackle some of Pakistan’s most pressing environmental issues—such as smog, marine debris and overall pollution
KARACHI: (UrduPoint /UrduPoint / Pakistan Point News-July 29th, 2025) In a remarkable achievement for local innovation, Cola NEXT has boldly surpassed multinational corporations by setting a new industry benchmark in sustainable packaging. Proudly Pakistani, Cola NEXT introduces its latest breakthrough: an advanced, eco-friendly PET bottle design that significantly reduces plastic usage by 8-10% compared to conventional standards.
Central to this industry-leading innovation is the revolutionary 26/22 cap, replacing the older 1881 version. The new cap not only enhances the consumer experience with superior sealing that keeps beverages fresher for longer but also significantly cuts down plastic consumption, directly contributing to environmental sustainability.
Cola NEXT’s innovative packaging initiative is thoughtfully designed to tackle some of Pakistan’s most pressing environmental issues—such as smog, marine debris, and overall pollution. By choosing Cola NEXT, consumers are actively participating in creating a cleaner, healthier Pakistan.
Key Highlights of Cola NEXT’s Sustainable Packaging:
Significant Plastic Reduction: 8-10% less plastic per bottle, with future projections of up to 30%.
Advanced Cap Technology: The 26/22 cap design ensures better freshness, reduces plastic use, and boosts production efficiency.
Unmatched Durability: Tested extensively to ensure reliability during transportation and prolonged shelf life.
Environmental Leadership: Directly addresses pollution challenges and supports nationwide sustainability efforts.
Energy Conscious Manufacturing: Cola NEXT’s commitment includes state-of-the-art machinery and solar-powered factories, enhancing energy efficiency and fostering a greener environment.
Cola NEXT’s dedication to continuous innovation ensures that sustainability remains at the core of its business practices, consistently setting new standards and paving the way for a brighter, greener future.
Experience the future of sustainable beverages with Cola NEXT—because your choices today shape Pakistan’s tomorrow.
Cola NEXT is a visionary beverage dedicated to innovation, sustainability, and exceptional quality. Committed to reducing environmental impact, Cola NEXT consistently offers products that customers can trust and proudly enjoy.
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Houseplant clinic: why won’t my wax plant bloom? | Houseplants
What’s the problem?
My Hoya carnosa cutting, taken from my father’s treasured plant, bloomed once, in 2022, but has not flowered since. How can I encourage it?Diagnosis
Hoyas, often known as wax plants, have a reputation for thriving on “benign neglect”. They flower best when slightly stressed, as this triggers their reproductive mode. Regular watering and abundant nutrients will encourage leaf growth rather than blooms.Prescription
Allow the soil to completely dry out between waterings – typically, every two to four weeks in autumn and winter, and more often in warmer months. Limit fertiliser applications, as hoyas flower better in nutrient-poor conditions. Ensure bright but indirect sunlight, as too much direct sunlight or a lack of darkness at night can disrupt their flowering cycle. Conversely, some people recommend “sun-stressing” their hoyas. Also, consider a slight drop in temperature overnight.Prevention
Maintain a balance between attentive care and minimal interference. Aim for indirect lighting, cooler night-time temperatures, and less frequent feeding and watering. The mild stress should boost flowering potential.Got a plant dilemma? Email saturday@theguardian.com with ‘Houseplant clinic’ in the subject line
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Kepler-139f: The massive planet that remained ‘invisible’ to scientists for years
It is well known that the universe still hides millions of secrets that remain to be discovered from the dark silences of spaceRecently, astronomers made a discovery hidden in plain sight. Despite orbiting a star system already known to host several planets, this giant exoplanet somehow evaded detection for years.Astronomers announced the discovery of Kepler‑139f, which is a massive exoplanet approximately 36 times the mass of Earth, around twice as large as Neptune, yet it stayed invisible until 2025. Orbiting a G‑type star similar to our Sun, Kepler‑139f completes one orbit in about 355 days, roughly at 1 AU distance, as reported in a study published in The Astrophysical Journal Letters.
So, why was such a large planet missed for so long
The key to its secret lies in its unusual orbit. NASA’s Kepler Space Telescope, which discovered thousands of exoplanets through the transit method, only detects planets that pass directly between the star and Earth, causing slight dips in starlight. Kepler‑139f’s orbit is inclined, so it never transits from our vantage point, remaining invisible to the primary detection method.
What method did scientists use this time
To find out Kepler‑139f, scientists used a combination of radial velocity (RV) and transit timing variations (TTVs). RV measures how a star wobbles due to gravitational pull from orbiting planets, while TTVs capture irregularities in known planets’ transit timings caused by unseen companions. As Caleb Lammers, a graduate student in the Department of Astrophysical Science at Princeton and co-author of the study, told Space.com, “When you observe TTVs that cannot be attributed to the known planets, you can be fairly confident that there is an unseen body in the system”.After the 2023 discovery of Kepler‑139e, scientists went back and rechecked earlier data using RV and TTV methods. This helped them spot Kepler‑139f, hidden between the smaller planet Kepler‑139c and the gas giant Kepler‑139e. According to Lammers, “Many planetary systems likely host invisible worlds—particularly in their distant orbits.” Since traditional planet-hunting methods rely on perfect orbital alignment with Earth, many such planets can go unnoticed. That’s why using a mix of techniques like RV, TTV, and upcoming missions like ESA’s PLATO, launching in 2026, will be important in finding more of these hidden, massive worlds.
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After living in it for just one month, Ellen DeGeneres and Portia de Rossi are selling U.K. farmhouse for $30 million – Morningstar
- After living in it for just one month, Ellen DeGeneres and Portia de Rossi are selling U.K. farmhouse for $30 million Morningstar
- Exclusive | Ellen DeGeneres and Portia de Rossi Are Putting Their U.K. Farm on the Market for $30 Million The Wall Street Journal
- Ellen DeGeneres: I moved to the UK because of Trump BBC
- Ellen DeGeneres eyes talk show comeback from England The Express Tribune
- Why is Ellen DeGeneres selling her £22.5m UK home? Take our quiz The Times
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