Author: admin

  • Films directed by women drop to seven-year low in 2025, study finds

    Films directed by women drop to seven-year low in 2025, study finds

    Female directors were behind only nine of the 100 top-grossing films of 2025, accounting for roughly 8.1% of the total

    A recent industry report shows a…

    Continue Reading

  • Society Matters: Year in Pictures

    Society Matters: Year in Pictures

    S.B. County Animal Care Foundation President and Co-founder Linda Greco, Event Chair Lee Heller, Event Emcees…

    Continue Reading

  • ‘Gotten Everything He Wanted’ — Source

    ‘Gotten Everything He Wanted’ — Source

    It sounds like Timothée Chalamet is getting a little tired of Kylie Jenner. Reports indicate the Academy Award nominee and the reality star’s relationship is on thin ice at the moment.

    The Marty Supreme actor was notably absent from Kris…

    Continue Reading

  • Stark Manifold Dynamics With Rydberg Atoms Advances Understanding Of Thermalization

    Stark Manifold Dynamics With Rydberg Atoms Advances Understanding Of Thermalization

    The tendency of isolated systems to reach a stable, predictable state, known as thermalization, remains a fundamental question in physics, with the eigenstate thermalization hypothesis offering one potential explanation. Sarah E. Spielman,…

    Continue Reading

  • Shi, J. et al. Active biointegrated living electronics for managing inflammation. Science 384, 1023–1030 (2024).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • Chen, C., Ding, S. & Wang, J. Digital health for aging populations. Nat. Med. 29, 1623–1630 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Wang, C. et al. Bioadhesive ultrasound for long-term continuous imaging of diverse organs. Science 377, 517–523 (2022).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • Gao, W. et al. Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis. Nature 529, 509–514 (2016).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Musk, E. An integrated brain-machine interface platform with thousands of channels. J. Med. Internet Res. 21, e16194 (2019).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Chortos, A., Liu, J. & Bao, Z. Pursuing prosthetic electronic skin. Nat. Mater. 15, 937–950 (2016).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • Williams, E. Environmental effects of information and communications technologies. Nature 479, 354–358 (2011).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • Shi, H. H. et al. Sustainable electronic textiles towards scalable commercialization. Nat. Mater. 22, 1294–1303 (2023).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • Chen, S. How much energy will AI really consume? The good, the bad and the unknown. Nature 639, 22–24 (2025).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • Kim, H. J., Koo, J. H., Lee, S., Hyeon, T. & Kim, D.-H. Materials design and integration strategies for soft bioelectronics in digital healthcare. Nat. Rev. Mater. 10, 654–673 (2025).

    Article 
    ADS 

    Google Scholar 

  • Nikolka, M., Göke, S., Burkacky, O., Spiller, P. & Patel, M. Unlocking net-zero in semiconductor manufacturing. Nat. Rev. Electr. Eng. 1, 487–488 (2024).

    Article 

    Google Scholar 

  • McCulloch, I., Chabinyc, M., Brabec, C., Nielsen, C. B. & Watkins, S. E. Sustainability considerations for organic electronic products. Nat. Mater. 22, 1304–1310 (2023).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • The Global E-Waste Monitor 2024–Electronic Waste Rising Five Times Faster than Documented e-Waste Recycling (United Nations, 2024); https://ewastemonitor.info/wp-content/uploads/2024/12/GEM_2024_EN_11_NOV-web.pdf.

  • Yang, Q. et al. Ecoresorbable and bioresorbable microelectromechanical systems. Nat. Electron. 5, 526–538 (2022).

    Article 
    CAS 

    Google Scholar 

  • Jeong, H. et al. Novel eco-friendly starch paper for use in flexible, transparent and disposable organic electronics. Adv. Funct. Mater. 28, 1704433–1704442 (2018).

    Article 

    Google Scholar 

  • Zhang, Z. et al. Recyclable vitrimer-based printed circuit boards for sustainable electronics. Nat. Sustain. 7, 616–627 (2024).

    Article 

    Google Scholar 

  • Vũ, N. Đ et al. Gallium-catalyzed recycling of silicone waste with boron trichloride to yield key chlorosilanes. Science 388, 392–400 (2025).

    Article 
    ADS 
    PubMed 

    Google Scholar 

  • Park, H. et al. Organic flexible electronics with closed-loop recycling for sustainable wearable technology. Nat. Electron. 7, 39–50 (2024).

    Article 
    CAS 

    Google Scholar 

  • Corzo, D. et al. High-performing organic electronics using terpene green solvents from renewable feedstocks. Nat. Energy 8, 62–73 (2023).

    Article 
    ADS 

    Google Scholar 

  • Min, J. et al. An autonomous wearable biosensor powered by a perovskite solar cell. Nat. Electron. 6, 630–641 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Cordella, M., Alfieri, F. & Sanfelix, J. Reducing the carbon footprint of ICT products through material efficiency strategies: a life cycle analysis of smartphones. J. Ind. Ecol. 25, 448–464 (2021).

    Article 

    Google Scholar 

  • Peng, P. & Shehabi, A. Regional economic potential for recycling consumer waste electronics in the United States. Nat. Sustain. 6, 93–102 (2023).

    Article 

    Google Scholar 

  • Moni, S. M., Mahmud, R., High, K. & Carbajales-Dale, M. Life cycle assessment of emerging technologies: a review. J. Ind. Ecol. 24, 52–63 (2020).

    Article 
    CAS 

    Google Scholar 

  • Strazza, C. et al. Technology Readiness Level—Guidance Principles for Renewable Energy Technologies Final Report (European Commission, Directorate-General for Research and Innovation, 2017).

  • Huijbregts, M. A. J. et al. ReCiPe2016: a harmonised life cycle impact assessment method at midpoint and endpoint level. Int. J. Life Cycle Assess. 22, 138–147 (2017).

    Article 

    Google Scholar 

  • Dexcom G6 CGM system for personal use. Dexcom https://provider.dexcom.com/products/g6-personal-cgm (2025).

  • Williams, E. D., Ayres, R. U. & Heller, M. The 1.7 kilogram microchip: energy and material use in the production of semiconductor devices. Environ. Sci. Technol. 36, 5504–5510 (2002).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • Yang, Y. et al. A laser-engraved wearable sensor for sensitive detection of uric acid and tyrosine in sweat. Nat. Biotechnol. 38, 217–224 (2020).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Xu, Y. et al. Pencil–paper on-skin electronics. Proc. Natl Acad. Sci. USA 117, 18292–18301 (2020).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Bonnassieux, Y. et al. The 2021 flexible and printed electronics roadmap. Flex. Print. Electron. 6, 023001 (2021).

    Article 
    CAS 

    Google Scholar 

  • Schaubroeck, T. et al. Attributional & consequential life cycle assessment: definitions, conceptual characteristics and modelling restriction. Sustainability 13, 7386–7433 (2021).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Norgate, T. & Haque, N. Using life cycle assessment to evaluate some environmental impacts of gold production. J. Clean. Prod. 29–30, 53–63 (2012).

    Article 

    Google Scholar 

  • Bigum, M., Damgaard, A., Scheutz, C. & Christensen, T. H. Environmental impacts and resource losses of incinerating misplaced household special wastes (WEEE, batteries, ink cartridges and cables). Resour. Conserv. Recycl. 122, 251–260 (2017).

    Article 

    Google Scholar 

  • Global smartphone market soared 7% in 2024 as vendors prepare for tricky 2025. canalys.com https://canalys.com/newsroom/worldwide-smartphone-market-2024 (2025).

  • Yuk, H., Lu, B. & Zhao, X. Hydrogel bioelectronics. Chem. Soc. Rev. 48, 1642–1667 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Feig, V. R., Tran, H. & Bao, Z. Biodegradable polymeric materials in degradable electronic devices. ACS Cent. Sci. 4, 337–348 (2018).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Fujisaki, Y. et al. Transparent nanopaper-based flexible organic thin-film transistor array. Adv. Funct. Mater. 24, 1657–1663 (2014).

    Article 
    CAS 

    Google Scholar 

  • Material property data. MatWeb https://www.matweb.com/index.aspx (2025).

  • Fan, Z.-J. et al. Facile synthesis of graphene nanosheets via Fe reduction of exfoliated graphite oxide. ACS Nano 5, 191–198 (2011).

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Worfolk, B. J. et al. Ultrahigh electrical conductivity in solution-sheared polymeric transparent films. Proc. Natl Acad. Sci. USA 112, 14138–14143 (2015).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Someya, T., Bao, Z. & Malliaras, G. G. The rise of plastic bioelectronics. Nature 540, 379–385 (2016).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • Liu, H., Liu, D., Yang, J., Gao, H. & Wu, Y. Flexible electronics based on organic semiconductors: from patterned assembly to integrated applications. Small 19, 2206938 (2023).

    Article 
    CAS 

    Google Scholar 

  • Chu, M. et al. Co-recycling of plastics and other waste materials. Nat. Rev. Clean Technol. 1, 320–332 (2025).

    Article 

    Google Scholar 

  • Dai, Y. et al. Soft hydrogel semiconductors with augmented biointeractive functions. Science 386, 431–439 (2024).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Piao, Z., Agyei Boakye, A. A. & Yao, Y. Environmental impacts of biodegradable microplastics. Nat. Chem. Eng. 1, 661–669 (2024).

    Article 

    Google Scholar 

  • Peng, J. et al. Surface coordination layer passivates oxidation of copper. Nature 586, 390–394 (2020).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • Bell, E. L. et al. Directed evolution of an efficient and thermostable PET depolymerase. Nat. Catal. 5, 673–681 (2022).

    Article 
    CAS 

    Google Scholar 

  • Jiang, Y. et al. A universal interface for plug-and-play assembly of stretchable devices. Nature 614, 456–462 (2023).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • Sacchi, R. et al. Prospective environmental impact assement (premise): a streamlined approach to producing databases for prospective life cycle assessment using integrated assessment models. Renew. Sustain. Energy Rev. 160, 112311 (2022).

    Article 

    Google Scholar 

  • Yoshimoto, M. & Izumi, S. Recent progress of biomedical processor SoC for wearable healthcare application: a review. IEICE Trans. Electron. 102, 245–259 (2019).

    Article 
    ADS 

    Google Scholar 

  • Malmodin, J. & Lundén, D. The energy and carbon footprint of the global ICT and E&M sectors. Sustainability 10, 3027–3057 (2018).

  • Ercan M., Malmodin J., Bergmark P., Kimfalk E., & Nilsson E. Life cycle assessment of a smartphone. In Proc. ICT for Sustainability 2016 124–133 (Atlantis Press, 2016).

  • Suckling, J. & Lee, J. Redefining scope: the true environmental impact of smartphones? Int. J. Life Cycle Assess. 20, 1181–1196 (2015).

    Article 
    CAS 

    Google Scholar 

  • Zhang, T. et al. Life cycle assessment (LCA) of circular consumer electronics based on IC recycling and emerging PCB assembly materials. Sci. Rep. 14, 29183 (2024).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Zhang, M. et al. Towards sustainable perovskite light-emitting diodes. Nat. Sustain. 8, 315–324 (2025).

    Article 

    Google Scholar 

  • Yang, C. et al. A bioinspired permeable junction approach for sustainable device microfabrication. Nat. Sustain. 7, 1190–1203 (2024).

    Article 

    Google Scholar 

  • Li, P. et al. Monolithic silicon for high spatiotemporal translational photostimulation. Nature 626, 990–998 (2024).

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Malmodin J. & Lövehagen N. A methodology for simplified LCAs of electronic products. In 2024 Electronics Goes Green 2024+ (EGG) 1–12 (IEEE, 2024).

  • Zhang, Z. et al. DeltaLCA: comparative life-cycle assessment for electronics design. In Proc. ACM on Interactive, Mobile, Wearable and Ubiquitous Technologies, Vol. 8, 1–29 (ACM, 2024).

  • Teer J. & Bertolini M. Reaching Breaking Point: The Semiconductor and Critical Raw Material Ecosystem at a Time of Great Power Rivalry (The Hague Centre for Strategic Studies, 2022); https://hcss.nl/wp-content/uploads/2022/10/Reaching-breaking-point-full-HCSS-2022-revised.pdf.

  • Pizzol, M. et al. Normalisation and weighting in life cycle assessment: quo vadis?. Int. J. Life Cycle Assess. 22, 853–866 (2017).

    Article 

    Google Scholar 

  • Wang, B., Tian, X., Stranks, S. D. & You, F. Transitioning photovoltaics to all-perovskite tandems reduces 2050 climate change impacts of PV sector by 16%. Environ. Sci. Technol. 59, 9540–9551 (2025).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • Bass, F. M. A new product growth for model consumer durables. Manag. Sci. 50, 1825–1832 (2004).

    Article 

    Google Scholar 

  • Kaminski, J. Diffusion of innovation theory: theory in nursing informatics column. Can. J. Nurs. Inform. 6, 1–6 (2011).

  • Norton, J. A. & Bass, F. M. A diffusion theory model of adoption and substitution for successive generations of high-technology products. Manag. Sci. 33, 1069–1086 (1987).

    Article 

    Google Scholar 

  • Sultan, F., Farley, J. U. & Lehmann, D. R. A meta-analysis of applications of diffusion models. J. Mark. Res. 27, 70–77 (1990).

    Article 

    Google Scholar 

  • Managing Complications in Pregnancy and Childbirth: A Guide for Midwives and Doctors (World Health Organization, 2003).

  • Zhou, B. et al. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet 398, 957–980 (2021).

    Article 

    Google Scholar 

  • Cardiovascular diseases (CVDs). WHO https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds) (2021).

  • Papolos, A., Narula, J., Bavishi, C., Chaudhry, F. A. & Sengupta, P. P. U.S. hospital use of echocardiography: insights from the nationwide inpatient sample. J. Am. Coll. Cardiol. 67, 502–511 (2016).

    Article 
    PubMed 

    Google Scholar 

  • Pawar P. Apple Watch statistics by revenue, sales, series, market share, country, users and usage. Coolest Gadgets https://www.coolest-gadgets.com/apple-watches-statistics/ (2023).

  • Forti, V., Baldé, K. & Kuehr, R. E-waste Statistics: Guidelines on Classifications, Reporting and Indicators (United Nations Univ., 2018).

  • Electrical and Electronic Equipment Placed on Market Calculation Tool Manual (UNITAR, 2023); https://academy-ce.info/wp-content/uploads/2024/02/ENG-EEE-POM-calculation-tool-manual.pdf.

  • Miller, T. R., Duan, H., Gregory, J., Kahhat, R. & Kirchain, R. Quantifying domestic used electronics flows using a combination of material flow methodologies: a US case study. Environ. Sci. Technol. 50, 5711–5719 (2016).

    Article 
    ADS 
    CAS 
    PubMed 

    Google Scholar 

  • Weibull formulas. What are the basic lifetime distribution models used for non-repairable populations? NIST https://www.itl.nist.gov/div898/handbook/apr/section1/apr162.htm?utm (2025).

  • Ciroth, A., Muller, S., Weidema, B. & Lesage, P. Empirically based uncertainty factors for the pedigree matrix in ecoinvent. Int. J. Life Cycle Assess. 21, 1338–1348 (2016).

    Article 

    Google Scholar 

  • Uncertainties. Ecoinvent Support https://support.ecoinvent.org/uncertainties (2025).

  • Gong, J., Darling, S. B. & You, F. Perovskite photovoltaics: life-cycle assessment of energy and environmental impacts. Energy Environ. Sci. 8, 1953–1968 (2015).

    Article 
    CAS 

    Google Scholar 

  • Worrell, E. et al. Potentials and Policy Implications of Energy and Material Efficiency Improvement (United Nations, 1997).

  • Zio XT® long-term continuous monitoring service. iRhythm Technologies https://www.irhythmtech.com/us/en/solutions-services/irhythm-service/zio-xt (2025).

  • Aktiia 24/7. Blood pressure monitor. Aktiia https://aktiia.com/uk/blood-pressure-monitor (2024).

Continue Reading

  • Random heteropolymers as enzyme mimics

    Random heteropolymers as enzyme mimics

  • Breslow, R. Artificial enzymes. Science 218, 532–537 (1982).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • DeGrado, W. F., Wasserman, Z. R. & Lear, J. D. Protein design, a minimalist approach. Science 243, 622–628 (1989).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Kuhlman, B. et al. Design of a novel globular protein fold with atomic-level accuracy. Science 302, 1364–1368 (2003).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Castriciano, M. A., Romeo, A., Baratto, M. C., Pogni, R. & Scolaro, L. M. Supramolecular mimetic peroxidase based on hemin and PAMAM dendrimers. Chem. Commun. 14, 688–690 (2008).

    Article 

    Google Scholar 

  • Schmidt, B. V. K. J., Fechler, N., Falkenhagen, J. & Lutz, J.-F. Controlled folding of synthetic polymer chains through the formation of positionable covalent bridges. Nat. Chem. 3, 234–238 (2011).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Terashima, T. et al. Single-chain folding of polymers for catalytic systems in water. J. Am. Chem. Soc. 133, 4742–4745 (2011).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Wiester, M. J., Ulmann, P. A. & Mirkin, C. A. Enzyme mimics based upon supramolecular coordination chemistry. Angew. Chem. Int. Ed. 50, 114–137 (2011).

    Article 
    CAS 

    Google Scholar 

  • Kaphan, D. M., Levin, M. D., Bergman, R. G., Raymond, K. N. & Toste, F. D. A supramolecular microenvironment strategy for transition metal catalysis. Science 350, 1235–1238 (2015).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Nath, I., Chakraborty, J. & Verpoort, F. Metal organic frameworks mimicking natural enzymes: a structural and functional analogy. Chem. Soc. Rev. 45, 4127–4170 (2016).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Liu, Q., Wang, H., Shi, X. H., Wang, Z.-G. & Ding, B. Q. Self-assembled DNA/peptide-based nanoparticle exhibiting synergistic enzymatic activity. ACS Nano 11, 7251–7258 (2017).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Mundsinger, K., Izuagbe, A., Tuten, B. T., Roesky, P. W. & Barner-Kowollik, C. Single chain nanoparticles in catalysis. Angew. Chem. Int. Ed. 63, e202311734 (2024).

    Article 
    CAS 

    Google Scholar 

  • Lutz, J.-F., Ouchi, M., Liu, D. R. & Sawamoto, M. Sequence-controlled polymers. Science 341, 1238149 (2013).

    Article 
    PubMed 

    Google Scholar 

  • Lombardi, A., Pirro, F., Maglio, O., Chino, M. & DeGrado, W. F. De novo design of four-helix bundle metalloproteins: one scaffold, diverse reactivities. Acc. Chem. Res. 52, 1148–1159 (2019).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Rose, G. D., Fleming, P. J., Banavar, J. R. & Maritan, A. A backbone-based theory of protein folding. Proc. Natl Acad. Sci. USA 103, 16623–16633 (2006).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Zaccai, G. How soft is a protein? A protein dynamics force constant measured by neutron scattering. Science 288, 1604–1607 (2000).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Henzler-Wildman, K. & Kern, D. Dynamic personalities of proteins. Nature 450, 964–972 (2007).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Magazù, S. et al. Protein dynamics as seen by (quasi) elastic neutron scattering. Biochim. Biophys. Acta Gen. Subj. 1861, 3504–3512 (2017).

    Article 
    PubMed 

    Google Scholar 

  • Robertson, D. E. et al. Design and synthesis of multi-haem proteins. Nature 368, 425–432 (1994).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Sugase, K., Dyson, H. J. & Wright, P. E. Mechanism of coupled folding and binding of an intrinsically disordered protein. Nature 447, 1021–1025 (2007).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Hilburg, S. L., Ruan, Z., Xu, T. & Alexander-Katz, A. Behavior of protein-inspired synthetic random heteropolymers. Macromolecules 53, 9187–9199 (2020).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Jiang, T. et al. Single-chain heteropolymers transport protons selectively and rapidly. Nature 577, 216–220 (2020).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Daghrir, R. & Drogui, P. Tetracycline antibiotics in the environment: a review. Environ. Chem. Lett. 11, 209–227 (2013).

    Article 
    CAS 

    Google Scholar 

  • Dill, K. A. et al. Principles of protein folding — a perspective from simple exact models. Protein Sci. 4, 561–602 (1995).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Ruan, Z. et al. Population-based heteropolymer design to mimic protein mixtures. Nature 615, 251–258 (2023).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Artar, M., Souren, E. R. J., Terashima, T., Meijer, E. W. & Palmans, A. R. A. Single chain polymeric nanoparticles as selective hydrophobic reaction spaces in water. ACS Macro Lett. 4, 1099–1103 (2015).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Hoshino, Y. et al. The rational design of a synthetic polymer nanoparticle that neutralizes a toxic peptide in vivo. Proc. Natl Acad. Sci. USA 109, 33–38 (2012).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Popot, J.-L. et al. Amphipols from A to Z. Annu. Rev. Biophys. 40, 379–408 (2011).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Chakraborty, A. K. & Shakhnovich, E. I. Phase behavior of random copolymers in quenched random media. J. Chem. Phys. 103, 10751–10763 (1995).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Geissler, P. L. & Shakhnovich, E. I. Mechanical response of random heteropolymers. Macromolecules 35, 4429–4436 (2002).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Panganiban, B. et al. Random heteropolymers preserve protein function in foreign environments. Science 359, 1239–1243 (2018).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Koshland, D. E. Jr The key–lock theory and the induced fit theory. Angew. Chem. Int. Ed. Engl. 33, 2375–2378 (1995).

    Article 

    Google Scholar 

  • Jayapurna, I. et al. Sequence design of random heteropolymers as protein mimics. Biomacromolecules 24, 652–660 (2023).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Hoshino, T. & Sato, T. Squalene–hopene cyclase: catalytic mechanism and substrate recognition. Chem. Commun. 4, 291–301 (2002).

    Article 

    Google Scholar 

  • Moffet, D. A. et al. Peroxidase activity in heme proteins derived from a designed combinatorial library. J. Am. Chem. Soc. 122, 7612–7613 (2000).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Walker, F. A. Models of the bis-histidine-ligated electron-transferring cytochromes. Comparative geometric and electronic structure of low-spin ferro- and ferrihemes. Chem. Rev. 104, 589–616 (2004).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Tronnet, A. et al. Star-like polypeptides as simplified analogues of horseradish peroxidase (HRP) metalloenzymes. Macromol. Biosci. 24, 2400155–2400155 (2024).

    Article 
    CAS 

    Google Scholar 

  • Yu, H. et al. Mapping composition evolution through synthesis, purification, and depolymerization of random heteropolymers. J. Am. Chem. Soc. 146, 6178–6188 (2024).

    Article 
    ADS 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Arbe, A., Colmenero, J., Monkenbusch, M. & Richter, D. Dynamics of glass-forming polymers: “homogeneous” versus “heterogeneous” scenario. Phys. Rev. Lett. 81, 590–593 (1998).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Hart-Cooper, W. M., Clary, K. N., Toste, F. D., Bergman, R. G. & Raymond, K. N. Selective monoterpene-like cyclization reactions achieved by water exclusion from reactive intermediates in a supramolecular catalyst. J. Am. Chem. Soc. 134, 17873–17876 (2012).

    Article 
    ADS 
    PubMed 
    CAS 

    Google Scholar 

  • Hammer, S. C., Marjanovic, A., Dominicus, J. M., Nestl, B. M. & Hauer, B. Squalene hopene cyclases are protonases for stereoselective Brønsted acid catalysis. Nat. Chem. Biol. 11, 121–126 (2015).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Gibney, B. R. & Dutton, P. L. Histidine placement in de novo–designed heme proteins. Protein Sci. 8, 1888–1898 (1999).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Walker, F. A., Reis, D. & Balke, V. L. Models of the cytochromes b. 5. EPR studies of low-spin iron(III) tetraphenylporphyrins. J. Am. Chem. Soc. 106, 6888–6898 (1984).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Murphy, E. A. et al. High-throughput generation of block copolymer libraries via click chemistry and automated chromatography. Macromolecules 58, 8369–8376 (2025).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Cochran, A. G. & Schultz, P. G. Peroxidase-activity of an antibody heme complex. J. Am. Chem. Soc. 112, 9414–9415 (1990).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Tracy, T. S. Atypical cytochrome P450 kinetics. Drugs R D 7, 349–363 (2006).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Wu, G.-R. et al. Efficient degradation of tetracycline antibiotics by engineered myoglobin with high peroxidase activity. Molecules 27, 8660 (2022).

    Article 
    PubMed 
    PubMed Central 
    CAS 

    Google Scholar 

  • Jaacks, V. A novel method of determination of reactivity ratios in binary and ternary copolymerizations. Makromolek. Chem. 161, 161–172 (1972).

    Article 
    CAS 

    Google Scholar 

  • Flynn, P. F., Mattiello, D. L., Hill, H. D. W. & Wand, A. J. Optimal use of cryogenic probe technology in NMR studies of proteins. J. Am. Chem. Soc. 122, 4823–4824 (2000).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Andreini, C., Cavallaro, G., Lorenzini, S. & Rosato, A. MetalPDB: a database of metal sites in biological macromolecular structures. Nucleic Acids Res. 41, D312–D319 (2013).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Ravel, B. & Newville, M. ATHENA, ARTEMIS, HEPHAESTUS: data analysis for X-ray absorption spectroscopy using IFEFFIT. J. Synchrotron Radiat. 12, 537–541 (2005).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Martínez, L., Andrade, R., Birgin, E. G. & Martínez, J. M. PACKMOL: a package for building initial configurations for molecular dynamics simulations. J. Comput. Chem. 30, 2157–2164 (2009).

    Article 
    ADS 
    PubMed 

    Google Scholar 

  • Shu, J. Y. et al. Amphiphilic peptide−polymer conjugates based on the coiled-coil helix bundle. Biomacromolecules 11, 1443–1452 (2010).

    Article 
    PubMed 
    CAS 

    Google Scholar 

  • Continue Reading

  • Shrewsbury Food Hub urges people to use its surplus veg

    Shrewsbury Food Hub urges people to use its surplus veg

    A charity that collects surplus food from shops and farms and shares it out, has urged people to help themselves to vegetables after being inundated with them.

    Ali Thomas, from Shrewsbury Food Hub, revealed the group gathered about four tonnes, or 400 trays of food, on Christmas Eve alone from supermarkets and wholesalers.

    “We have been completely inundated with vegetables,” she said.

    The charity distributes to places such as domestic abuse safe houses, foodbanks and hospices, but everyone is invited to collect produce for themselves or their friends and neighbours with collection points open on Friday.

    Continue Reading

  • USITC Votes To Continue Investigations for Chromium Trioxide from India and Turkey Chromium Trioxide from India and Turkey

    December 31, 2025

    News Release 25-133

    Inv. No(s).

    701-TA-779 ,

    731-TA-1765-1766

    Contact: Jennifer Andberg
    , 202-205-1819

    USITC Votes To Continue Investigations for Chromium Trioxide from India and Turkey Chromium Trioxide from India and Turkey

    The U.S. International Trade Commission (Commission or USITC) today determined that there is a reasonable indication that a U.S. industry is materially injured due to imports of chromium trioxide from India and Turkey that are allegedly sold in the United States at less than fair value and subsidized by the government of India.

    Chair Amy A. Karpel and Commissioners David S. Johanson and Jason E. Kearns voted in the affirmative.

    As a result of the Commission’s affirmative determinations, the U.S. Department of Commerce will continue its investigations of chromium trioxide from India and Turkey.

    The Commission’s public report, Chromium Trioxide from India and Turkey (Inv. Nos. No. 701-TA-779 and 731-TA-1765-1766 (Preliminary), USITC Publication 5968, January 2026), will contain the views of the Commission and information developed during the investigations.

    The report will be available by February 3, 2026; when available, it may be accessed on the USITC website.

    # # #

    Continue Reading

  • Psychic John Edward, FBI agent Bob Hilland talk new book ‘Chasing Evil’

    Psychic John Edward, FBI agent Bob Hilland talk new book ‘Chasing Evil’

    NEW YORK (WABC) — As we head into a new year, many people turn to the stars for guidance, checking their horoscopes or sometimes looking to psychics about what’s to come. But the two men at the center of this story have been using those gifts…

    Continue Reading

  • Redmi Turbo 5 Series Could Launch With New Dimensity Chips

    Redmi Turbo 5 Series Could Launch With New Dimensity Chips

    Redmi has been the subject of several recent leaks, and a new report has revealed the chipsets expected to power the upcoming Redmi Turbo 5 lineup.

    According to a tipster on Weibo, the standard Redmi Turbo 5 will be powered by the…

    Continue Reading