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  • Oncology Updates You Need to Know

    Oncology Updates You Need to Know

    Welcome to this week’s edition of The Targeted Pulse, your weekly wrap-up of the top developments in oncology. This week, we saw several breakthroughs in targeted therapies and FDA decisions, bringing renewed hope to patients and clinicians alike. From regulatory designations for promising new drugs to crucial clinical trials, here are the top stories that shaped the week.

    FDA Grants Orphan Status to Novel JAK2 Inhibitor for Polycythemia Vera

    The FDA has granted orphan drug designation to VGT-1849B, a new investigational drug for the treatment of polycythemia vera (PV). This rare blood cancer, caused by the JAK2 V617F mutation, results in an overproduction of blood cells. VGT-1849B is a novel peptide nucleic acid-based antisense oligonucleotide (ASO) that selectively targets and reduces the production of the JAK2 protein. Unlike current JAK inhibitors, this targeted approach is expected to have a better safety profile and fewer side effects. The orphan drug designation highlights the need for new treatment options for PV patients and provides incentives for the drug’s development.

    Abemaciclib Significantly Improves Overall Survival in High-Risk Early Breast Cancer

    Abemaciclib (Verzenio), in combination with endocrine therapy, has been shown to significantly improve overall survival in patients with high-risk, early breast cancer. This finding comes from a 7-year analysis of the phase 3 monarchE trial, which enrolled over 5600 patients. The 2-year treatment regimen with abemaciclib also provided long-term benefits in disease-free and distant relapse-free survival. The study’s results are considered “practice-changing,” establishing abemaciclib as a new standard of care for this patient population. The safety profile of the treatment remained consistent, with manageable adverse effects. The data validates the drug’s role in reducing the risk of recurrence.

    TT125-802 Gains FDA Fast Track Designation in NSCLC

    A new small-molecule bromodomain inhibitor, TT125-802, has been granted 2 fast track designations by the FDA for the treatment of advanced or metastatic non–small cell lung cancer (NSCLC). This dual designation applies to patients whose disease has progressed after treatment with either an EGFR or a KRAS G12C inhibitor. The fast track status is intended to expedite the drug’s development to address an urgent unmet medical need.

    Initial data from an ongoing phase 1 clinical trial has shown promising results, with durable responses in drug-resistant NSCLC. Notably, the drug’s safety profile is considered favorable, as it does not cause thrombocytopenia, a common adverse effect of similar inhibitors. This allows for higher dosing to maximize the antitumor effect.

    FDA Approves 3-Month Leuprolide Mesylate Formulation for Advanced Prostate Cancer

    The FDA has approved a new 3-month, ready-to-use, long-acting injectable formulation of leuprolide mesylate (Camcevi ETM) for the treatment of advanced prostate cancer. This new quarterly injection, which comes in a prefilled syringe, aims to simplify administration and reduce handling errors.

    The approval was based on a phase 3 clinical trial that demonstrated high efficacy, with 97.9% of patients achieving the primary end point of testosterone suppression to castrate levels. The trial also confirmed that the drug’s safety profile was consistent with other GnRH agonists, with common side effects being mild to moderate in intensity. This new formulation provides a convenient option for managing advanced prostate cancer through androgen deprivation therapy.

    FDA Grants Breakthrough Designation for ctDNA Test in Colorectal Cancer

    The Haystack MRD test, a circulating tumor DNA (ctDNA) assay developed by Quest Diagnostics, has received breakthrough device designation from the FDA. This designation recognizes the test’s potential to significantly improve the management of minimal residual disease (MRD) in patients with stage II colorectal cancer following surgery. The test uses ultrasensitive sequencing to detect microscopic cancer remnants in the bloodstream, often months before they would be visible on a CT scan.

    The designation will accelerate the test’s review and approval, bringing a more precise and timelier tool to clinicians. By identifying patients who may benefit from adjuvant therapy, the test can help guide personalized treatment decisions, reduce unnecessary chemotherapy exposure, and improve patient outcomes.

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    September 7, 2025
  • WCH Tokyo 25 preview: women’s 5000m | News | Tokyo 25

    WCH Tokyo 25 preview: women’s 5000m | News | Tokyo 25

    • Four fastest women in the history of the 5000m will be in Tokyo
    • Double Olympic champion Beatrice Chebet and defending champion Faith Kipyegon go head-to-head
    • Italy’s Nadia Battocletti and USA’s Josette Andrew have both bettered 14:30 this year

    The four fastest women in history will be in contention in the women’s 5000m at the World Athletics Championships Tokyo 25, though the focus will be on global champions Faith Kipyegon and Beatrice Chebet in what will be their first clash since the Paris 2024 Olympic Games.

    Chebet, the double Olympic champion, became the first woman to cover 5000m within 14 minutes with her world record of 13:58.06 at the Prefontaine Classic in July. The race, which doubled as the Kenyan Trials, also featured Agnes Ngetich and Gudaf Tsegay, who clocked 14:01.29 and 14:04.41 respectively.

    The 2022 silver medallist and a bronze medal winner a year after that, Chebet will be keen to complete her set of World Championship medals when she takes on Kipyegon, her idol and the defending champion.

    Kipyegon, 31, hasn’t raced in the 5000m since the Paris Olympics, where she took silver behind Chebet. Three weeks ago in Silesia, she threatened the long-standing world 3000m record with 8:07.04, the second-fastest time in history, bumping Chebet’s 8:11.56 down to third on the world all-time list.

    Chebet and Kipyegon will have reinforcement from Agnes Ngetich and Japan-based Margaret Akidor. Ngetich, the third-fastest woman in history at 5000m and world record-holder for 10km, has grown in confidence on the track this year with wins in Brussels and Miramar.

    The Kenyan quartet is aiming for a sweep of the medals, but Tsegay may have something to say about that. The Ethiopian, who won the world 5000m title in 2022 and the world 10,000m crown in 2023, will be keen to make amends after coming away from the Paris Olympics without a medal.

    Tsegay is joined on the Ethiopian team by world indoor 3000m champion Freweyni Hailu, who set a PB of 14:19.33 in Rome earlier this year, world U20 record-holder Birke Haylom, and two-time world U20 champion Medina Eisa. It’s not clear yet exactly which three team members will take to the start line.

    The 5000m won’t solely be an East African battle, though.

    Olympic 10,000m silver medallist Nadia Battocletti reduced her own Italian record to 14:23.15 earlier this year. She has also set national records at 3000m (8:26.27) and 5km (14:32).

    Josette Andrews, making her outdoor World Championships debut, is the fastest US entrant after setting a PB of 14:25.37 in Rome. Teammate Shelby Houlihan, winner of the US 5000m title, could also feature.

    Australia’s Rose Davies, Spain’s Marta Garcia, and Britain’s double European U20 champion Innes FitzGerald are also among the athletes to watch.

    Michelle Katami for World Athletics

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    September 7, 2025
  • New Zealand stave off gallant Japan, clinch third place

    New Zealand stave off gallant Japan, clinch third place

    ULAANBAATAR (Mongolia)- New Zealand left nothing to chance and took control of the scoreboard early on but needed a last gasp effort to stave off a gallant Japan tally and win 93-92 in the bronze medal play-off on the concluding day of the FIBA U16 Asia Cup at the M Bank Arena on Sunday.

    The result helped the coach Ben Sheat’s team with their fourth successive medal in the competition in as many appearances. Japan a losing finalist of the 2022 edition in Qatar thus missed out on their fourth medal having appeared in all the eight editions so far.

    Both teams, however, had already booked their tickets to the FIBA U17 World Cup 2026 in Turkey.

    A strong support coming from the bench took New Zealand on a 11-0 spree, breaking away from an evenly poised tilt to close the opening quarter very strong.

    That surge seemed to keep them in good stead till Japan staged their fourth quarter rally.

    Keiji Koshi’s jumper followed by a long ranger put Japan ahead for the first time in the game with 25 seconds left.

    Jackson Couper’s success from beyond the arc brought New Zealand back to par, but when Shunzuko Miyazoto lined up at the foul-line, Japan seemed to have turned from being hunted to becoming the hunter.

    Miyazato found success only on one of the two attempts from the foul-stripe and in the following play, Marco Sula utilised a Japanese defense misread and his layup clinched the game for New Zealand.

    Tawhiri Cate was New Zealand’s highest scorer with 17 points and 7 assists.

    Koshi led all scorers with 24 points, 17 of them in the second half.

    FIBA

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    September 7, 2025
  • Top eight again: Poland down Dragons to advance

    Top eight again: Poland down Dragons to advance

    The official EuroBasket app

    RIGA (Latvia) – Poland booked a return trip to the Quarter-Finals of the FIBA EuroBasket with a workman-like 80-72 victory over Bosnia and Herzegovina.

    The 2022 Semi-Finalists Poland bounced back from two straight losses to finish the Group Phase to register consecutive top eight showings for first time since 1971.

    Turning Point

    Bosnia and Herzegovina came out of the game on fire and opened a 13-2 advantage early on. The lead was still double figures at 31-21 before Poland pulled within 34-33. The Dragons were up 44-40 at the break.

    Bosnia and Herzegovina extended the cushion to 55-47 but watched as Poland surged back with a 10-1 spurt to go ahead 57-56 – Poland’s first lead of the game. And they led 62-61 after 30 mintues. Poland opened some breathing run with an 11-2 spurt to make it 76-68 with 4 mintues to go.

    Poland kept up their defensive work and Jordan Loyd drained a jumper with 56 seconds to play for an 80-72 cushion to decide the game.

    TCL Player of the Game

    Jordan Loyd would not let Poland lose three straight games as he hit 3 three-pointers and scored 26 points while also adding 2 rebounds and 1 assist, steal and block each.

    Captain Mateusz Ponitka played his usual pivotal role in pouring in 19 points with 9 rebounds and 3 steals. At the other end, Jusuf Nurkic scored 20 points and John Roberson had 19 points in the loss before a late injury.

    Nurkic climbs again

    Nurkic moves into top five on Bosnia and Herzegovina’s EuroBasket scorers list

    Stats Don’t Lie

    Poland grabbed 16 offensive rebounds and took the points off turnovers category 19-12. The Poles also converted 24 of 29 free throws compared to just 11 of 20 for Bosnia and Herzegovina.

    Bottom Line

    Poland took another step to matching their magical run from three years ago when they reached the Semi-Finals for their first top four showing since 1971. Igor Milicic’s team will face Türkiye in the Quarter-Finals.

    Bosnia and Herzegovina were happy to advance from the group stage for the first time since 1993, but they will be disappointed about leaving Riga after just one game.

    They Said

    For more quotes, tune in to the official post-game press conference!

    FIBA

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    September 7, 2025
  • A year under CEO Niccol: Starbucks workers’ long fight for a union contract | US unions

    A year under CEO Niccol: Starbucks workers’ long fight for a union contract | US unions

    It’s been a year since Brian Niccol took the top job at Starbucks and promised change after years of bitter fighting with the company’s burgeoning union.

    “I deeply respect the right of partners to choose, through a fair and democratic process, to be represented by a union,” Niccol wrote in a letter to the union last September. “If our partners choose to be represented, I am committed to making sure we engage constructively and in good faith with the union and the partners it represents.”

    But 12 months on, the union and Niccol are still at loggerheads, according to workers, and the most successful corporate union drive in recent history has been stymied.

    More than 12,000 workers at nearly 650 Starbucks stores around the US have unionized since December 2021, the fastest-growing union campaign in modern history. The growth has come despite hundreds of allegations of union-busting, retaliation and unfair labor practices lodged against Starbucks by the union.

    Starbucks Workers United had made progress toward securing a first union contract with the company since bargaining sessions began in early 2024. But that progress has largely stalled since Niccol took over the company.

    His first year on the job began with implementing a new strategy for the company, which he dubbed “Back to Starbucks”, which outlined an emphasis on customer service, decreasing wait times for orders and improving in-store experiences.

    Niccol has praised the strategy, and the company had a record sales week on the release of its Fall menu this year after six consecutive quarters of same-store sales declines.

    But workers organizing at Starbucks have criticized the strategy, citing increased demands on workers, such as having to write personalized messages on customer drink orders, without improvements to staffing or pay.

    Brian Niccol speaks at the company’s leadership conference in Las Vegas on 10 June 2025. Photograph: Joshua Trujillo/Starbucks via Reuters

    A survey conducted by Starbucks Workers United and the Strategic Organizing Center of 737 Starbucks workers found 91% reported understaffing at their stores in the past three months, and 93% said the policy changes under Niccol either had no impact or worsened the customer experience.

    “It’s clear that ‘Back to Starbucks’ isn’t working and won’t succeed until we finalize a fair union contract with the hours, take-home pay and protections baristas need to do our jobs,” said Michelle Eisen, a spokesperson for Starbucks Workers United and a barista for 15 years.

    “Brian has talked about like simplifying the menu to make things easier for partners, and wanting to get customers in and out of the stores faster, but these changes that he’s rolled out haven’t accomplished any of those things,” said Jasmine Leli, a Starbucks barista since December 2021 at a Starbucks store in Cheektowaga, New York, the second store to unionize in the US. “We really need him to get back to the table to finalize this contract so that we can start to turn things around.”

    Leli warned Starbucks can expect further actions from unionized workers to force the company to get back to the bargaining table. The union has frequently utilized strikes and protests to address specific issues at stores.

    “We are going to do whatever it takes to get them back to the table so that we can start to address the issues with the wages, scheduling and staffing,” Leli added. “We are the ones that are working in the stores and interacting with the customers day in and day out, and partners want to be a part of making change in the workplace. So that’s why stores are joining the fight.”

    graphic 1

    Niccol’s exorbitant compensation has been a point of criticism for workers and labor advocates; Niccol received $97.8m in total compensation in 2024, 6,666 times more than the median annual salary of a Starbucks worker at $14,674, the biggest CEO-to-worker pay gap among the top 500 corporations in the US. Starbucks claimed its average compensation, including benefits for workers who work at least 20 hours a week, is $30 an hour.

    “If you’re the Starbucks CEO you get $96m for four months of work including a $5m bonus,” Senator Bernie Sanders wrote on social media in March. “If you’re a Starbucks union worker, the CEO is refusing to give you a decent raise to pay rent and buy groceries. Starbucks must end its greed & negotiate a fair union contract.”

    A spokesperson for Starbucks said in response to criticism of Niccol’s compensation: “Starbucks believes Brian has established himself as one of the most effective leaders in our industry, with a proven track record of delivering long-term value to employees, customers and shareholders. The majority of his reported first-year compensation reflects multi-year replacement equity grants, awarded to offset compensation forfeited upon his departure from Chipotle, which are now directly tied to Starbucks future performance.”

    The company also paid $3.8bn to shareholders in fiscal year 2024 through stock buybacks and dividends.

    Starbucks Workers United have criticized Niccol’s pay, his private jet use and the $81m spent by Starbucks on a June convention in Las Vegas for 14,000 store managers and other leaders.

    “It would take less than what Brian made in four months to settle fair contracts with our union,” stated the union in a recent video posted on Instagram.

    graphic 2

    In December 2024, thousands of baristas at Starbucks stores around the US went on strike, the largest strike in the company’s history, after the union claimed Starbucks backtracked on an agreement to finalize a deal.

    In April 2025, the union rejected a proposal from Starbucks for 2% pay increases, with 81% of unionized stores voting it down due to its failure to adequately address other economic benefits and provide an immediate pay hike. A new proposal has yet to materialize.

    In the midst of stalled negotiations, Starbucks Workers United has continued growing to 648 unionized stores, from 500 stores in September 2024.

    Diego Franco, a barista at Starbucks for five years at a unionized store in Chicago, Illinois, criticized the personalized note change when he says his store is often understaffed, resulting in long waits for orders.

    “If I’m a customer, I don’t care to read a personalized note on my cup when I’m already waiting 20 minutes for my drink, and as a worker, I’m getting chastised for not having a Sharpie at all times,” Franco said. “It’s been a huge mishandling of so much money, but the company continues to lose, thinking that Brian or any of our previous CEOs have had the answers.”

    “I believe if the company truly wanted to fix the problems happening in their stores, it could have happened by now,” he added. “Where the company might see a bottom line, I see human experiences, human lives that are affected by the work that we do. So I hope to preserve that and to make it better, not just for me and my co-workers, but for people who come in the stores.”

    A spokesperson for Starbucks said: “Since last April 2024, Starbucks and Workers United have held more than nine bargaining sessions over 20 days and three mediation sessions over five days with a federal mediator. We’ve reached over thirty meaningful agreements on hundreds of topics Workers United delegates told us were important to them. We are ready to finalize a reasonable contract for represented partners, but we need the union to return to the bargaining table to finish the job.”


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    September 7, 2025
  • iPhone Price Hike, Siri AI Upgrades, Buffett Criticism And More: This Week In Appleverse – Apple (NASDAQ:AAPL)

    iPhone Price Hike, Siri AI Upgrades, Buffett Criticism And More: This Week In Appleverse – Apple (NASDAQ:AAPL)

    The week was packed with news, and we’ve got it all covered. Here’s a quick roundup of the top Apple stories you might have missed.

    Apple Expected To Raise iPhone Prices This Month Despite Tim Cook’s Tariff Win

    Despite Apple Inc. AAPL CEO Tim Cook‘s successful handling of the tariff issue with the Trump administration, the company is anticipated to raise the prices of its new iPhones. The price hike is expected to be announced on Tuesday, September 9.

    Read the full article here.

    Apple’s AI Story Could Finally Take Off, Says Gene Munster

    Apple could be on the brink of a significant AI breakthrough. Gene Munster, the managing partner at Deepwater Asset Management, believes that Apple’s AI growth could finally take off. This comes after a Bloomberg report revealed that Apple is working on its own AI-powered search tool, set to launch in 2026.

    Read the full article here.

    See Also: Tesla Model Y L Averaging Over 10,000 Daily Orders Since Launch, Received 120,000 Orders To Date: Report

    Ross Gerber Slams Warren Buffett’s Apple Exit

    Ross Gerber, the CEO of Gerber Kawasaki Wealth and Investment Management, has dismissed comparisons between the current AI boom and the dot-com bubble. He also criticized Warren Buffett for reducing his stake in Apple. Gerber argues that the current AI boom may not be as unsustainable as it seems.

    Read the full article here.

    Apple Faces Class-Action Lawsuit

    Apple is facing a class-action lawsuit for allegedly using copyrighted books without permission to train its artificial intelligence systems. Authors Grady Hendrix and Jennifer Roberson filed the complaint in a Northern California federal court, claiming that Apple copied protected works without consent, credit, or compensation.

    Read the full article here.

    Apple Plans Siri AI Upgrade To Outpace Perplexity

    Apple is reportedly developing its own artificial intelligence-powered web search tool, internally dubbed “World Knowledge Answers,” for integration into Siri by 2026.

    Read the full article here.

    Read Next: 

    Photo courtesy: jamesteohart / Shutterstock.com

    Disclaimer: This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.

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    September 7, 2025
  • Technical training centre in St Blazey wins £250k grant

    Technical training centre in St Blazey wins £250k grant

    A new community group which provides engineering training has been given a £250,000 grant by the National Lottery.

    MPower Cornwall Community Interest Company (CIC) has a technical training centre for science, technology, engineering, maths and construction industry skill in St Blazey.

    Chief executive Duncan Mitchell said the grant would help the first intake of entrants, many of who were not in education, employment or training and some who had special needs, to learn skills to help them get jobs in engineering.

    He said the team’s objective was to “to equip those whom the traditional education system has not served well, with the skills that will help them into well-paid, rewarding jobs”.

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    September 7, 2025
  • Nature’s aid: Helping kids stay focused in class

    Nature’s aid: Helping kids stay focused in class | The Jerusalem Post

    Jerusalem Post/Health & Wellness/Parenting

    You don’t have to suffer from ADHD to experience concentration difficulties during studies. Children’s nutrition, together with certain medicinal plants, can make a difference.

    The beginning of the school year is an exciting time, but for children with ADHD it can be accompanied by stress, restlessness, and reduced focus
    The beginning of the school year is an exciting time, but for children with ADHD it can be accompanied by stress, restlessness, and reduced focus
    (photo credit: SHUTTERSTOCK)
    ByMAYA ABIR, NATUROPATH
    SEPTEMBER 7, 2025 14:00



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    September 7, 2025
  • 5 Things to Do at Breakfast to Keep Your Brain Sharp All Day

    5 Things to Do at Breakfast to Keep Your Brain Sharp All Day

    • The formula for staying sharp and clear-headed all day long starts with breakfast. 
    • For better focus, experts recommend drinking water before coffee and eating berries and eggs.
    • They also suggest pairing protein with carbs and limiting added sugar.

    When you eat breakfast, you’re doing more than just fueling your body. You’re also feeding your brain. Planned right, your morning meal can help you focus, stay energized and maybe even help you remember where you put your favorite water bottle. Why? “After a night of fasting, your brain is craving fuel and nutrients to help you focus and stay sharp, and skipping breakfast can leave you feeling foggy and sluggish,” says Lauren Manaker, M.S., RDN. Of course, what you eat is a critical part of the picture. But so is what you do before you take that first bite of food. And what you don’t eat matters, too. 

    So, what’s the ideal breakfast formula to keep your brain on top of its game? To find out, we explored the science and talked with registered dietitians to come up with this five-step plan to keep your brain functioning at its best all day long.  

    1. Hydrate Before Coffee 

    “Hydration is critical for brain function, and even mild dehydration can impair your focus, mental sharpness and attention,” says Anne Danahy, M.S., RDN. The link is so strong that research has found that poor hydration may negatively impact processing speed, memory and attention.

    Even though coffee contains water, drinking a glass of water first can make it easier to ensure you reach your H2O goals. How much water should you be drinking? Danahy recommends downing a glass of water before or with your coffee, and then every hour or two throughout the day. 

    2. Pair Protein with Carbs 

    Eating breakfast gives your brain an edge compared to skipping it. For instance, one study found that older folks who skipped breakfast just once or twice per week were more likely to perform poorly on tests of cognitive ability than regular breakfast eaters.

    But the quality and nutrient mix of that breakfast also matters. While classic breakfast foods like cereal, toast, fruit or oatmeal provide carbohydrates that your brain uses for fuel, balancing carbs with protein gives your meal more staying power. “Protein helps stabilize blood sugar when eaten with carbohydrates and keeps your energy and focus steady instead of crashing mid-morning,” notes Jamie Lee McIntyre, M.S., RDN. To get the protein you need in the a.m., think cottage cheese, yogurt, low-fat milk, soy milk, eggs, smoked salmon or even tuna fish.

    Don’t count out carbs entirely, though. “Your brain needs a mix of nutrients and, most importantly, glucose, to work well,” says Danahy. “If you’ve ever skipped meals and felt tired, foggy or ‘hangry,’ you’ve experienced the effects of low glucose levels on your brain.” Since our brains rely on breakfast to provide nutrients to power through the day, protein and carbohydrates are two key players that work better together.

    3. Eat Berries

    It’s hard to talk about a brain-healthy breakfast and not include a nod to berries. Berries are loaded with fiber, minerals, vitamins and polyphenols that all help support our brains. Their beautiful deep purple, red and blue colors come from anthocyanins. These potent antioxidants are believed to improve memory and cognitive health by increasing blood flow to the brain.

    Sure, you could eat berries any time of day. But why not get a jump start at breakfast? “Toss them in with your overnight oats, add them to a smoothie or top them with Greek yogurt and a sprinkle of granola and nuts,” suggests Danahy. Blueberries, blackberries, raspberries and strawberries all work. If fresh berries aren’t in season or are out of your budget, look for frozen berries, which are just as good for your body and brain. 

    4. Include Eggs 

    Eggs aren’t just a great source of protein. They also contain other brain-boosting nutrients, especially choline. This nutrient is crucial for supporting brain development, memory and mood, yet most of us don’t get enough of it, notes Manaker. Studies have linked higher choline intake with improved measures of cognitive performance, including faster verbal and visual memory.

    Because our bodies can’t make choline, we need to get it from foods or supplements. Just one large egg delivers 27% of your daily dose. So, “kick-start your morning with eggs by scrambling them up with veggies, making a quick avocado-and-egg toast, or by whipping up a simple omelet with your favorite fillings,” says Manaker.

    5. Limit Added Sugar 

    Your brain needs lots of key nutrients at breakfast. But what you skip matters, too. Even though your brain uses glucose (a simple sugar) as its preferred fuel, it’s better to get carbohydrates from fruits and whole grains rather than from added sugar. In fact, research has found a link between eating too much added sugar and poor cognitive and executive function. That includes everything from problem-solving to planning, fine motor skills and processing speed.

    In addition, added sugar is digested quickly, which can lead to blood sugar spikes and dips rather than providing sustained energy. Since most of us eat too much added sugar to begin with, a sugar-heavy breakfast practically guarantees you’ll overdo it throughout the course of the day. 

    Other Morning Strategies to Support Brain Health

    • Get natural sunlight: Starting your day with a bit of fresh air and sunshine can provide the boost your brain needs. “Natural sunlight helps regulate your circadian rhythm, which improves sleep quality—and better sleep is essential for memory consolidation,” notes Manaker.
    • Get some omega-3s: The omega-3 fats DHA and EPA are important for brain function, memory and cognitive well-being. Yet, few of us eat enough of them. The best way to get them is from fatty fish. Start your day with a slice of whole-grain toast topped with smoked salmon. Or, try some pickled herring. If you’re not much of a fish eater, McIntyre recommends adding an omega-3 supplement to your morning routine.
    • Get a good night’s sleep: Sleep is necessary to remove toxins from your brain that build up during the day. “When you don’t get enough sleep or have poor sleep quality, waking up frequently at night, your brain pays the price. You’re more likely to have problems with concentrating, focus and reaction time,” says Danahy. Aim for seven to nine hours per night. 
    • Move your body: Physical activity does more than benefit our bodies. It also keeps our brains happy and healthy. “Exercise increases blood flow to the brain, which can enhance focus, learning and memory,” says Manaker. “Even just 10 minutes of movement can make a difference.” If you can’t squeeze in a workout, even a quick walk can help.

    BRAIN-HEALTHY RECIPES TO TRY

    Our Expert Take

    “Just like every other part of your body, your brain needs a nutritious diet and a healthy lifestyle to do its job well,” says Danahy. “No single nutrient can keep your brain sharp and alert, but a healthy diet pattern [and] the way you eat over time, can help.” To start your day on the right foot, why not give your brain the nutrients it needs to perform at its very best? You can do this by hydrating with water before drinking your morning coffee, combining protein with carbohydrates, and choosing berries and eggs often. While you’re at it, try to limit added sugar, which can lead to blood sugar crashes that make it difficult to think straight. With this five-pronged plan, you’ll set yourself up for better mental clarity and focus throughout the day and support your long-term brain health to boot.

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    September 7, 2025
  • Companies Kick Off September With Deluge of Bond Sales – The Wall Street Journal

    1. Companies Kick Off September With Deluge of Bond Sales  The Wall Street Journal
    2. Companies tap US bond market for nearly $70 billion, starting September on a busy note  Reuters
    3. Merck Taps US Investment-Grade Bond Market for Verona Purchase  Bloomberg
    4. Credit Markets Near Records After $90 Billion Bond Sale Spree  Bloomberg
    5. US corporate debt market returns in force after market holiday  Reuters

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    September 7, 2025
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