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  • Bioiberica’s hyaluronic acid-based nutricosmetic makes the skin ‘glow’, study reveals

    Bioiberica’s hyaluronic acid-based nutricosmetic makes the skin ‘glow’, study reveals

    A new study has touted the anti-ageing and skin health-boosting effects of Bioiberica’s hyaluronic acid matrix ingredient, Dermial.


    With a high concentration of hyaluronic acid (>60%), collagen and a balance of other glycosaminoglycans (GAGs) including dermatan sulfate, Dermial is the first hyaluronic acid matrix ingredient on the market, according to Bioiberica.


    To assess the efficacy of Dermial as a nutricosmetic, the company performed a 12 week, randomised, double-blind, placebo-controlled clinical trial with 60 healthy female participants aged between 35 and 65 — all of which had visible signs of skin ageing.


    Published in Dermatology and Therapy, results revealed that daily supplementation with 60mg of Dermial can enhance skin hydration and reduce the appearance of facial wrinkles.1


    This suggests that hyaluronic acid, and specifically Dermial, could offer significant beauty from within benefits when taken daily.


     


    Beauty isn’t skin deep


    Hyaluronic acid has long been a staple of the cosmetics industry, with a vast number of topical products on the market utilising the super-ingredient to promote skin health and vitality.


    However, when applied topically, the ingredient can only achieve surface-level hydration, which doesn’t address dryness at a cellular level. (For more information on the rise of beauty from within ingredients, check out this interview with Tosla Nutricosmetics’ Monika Jesenko.)


    To overcome this issue, nutraceutical suppliers in both the joint health and beauty from within spaces have begun formulating with hyaluronic acid as an ingestible nutricosmetic ingredient — with promising results. 


    To assess the efficacy of Dermial specifically, Bioiberica conducted this clinical trial, which found that a low dose of 60mg a day could offer ‘powerful regenerative and moisturising properties’ alongside its unique glow-inducing effect, which was achieved six weeks into supplementation. 


    Researchers also observed: 


    • Significant improvements in the appearance of skin wrinkles in the Dermial group at six weeks
    • Those taking Dermial experienced significant improvements in skin smoothness by six weeks
    • Participants given Dermial had reduced skin roughness, while maintaining a more healthy skin pH balance (12 weeks)
    • The Dermial group had brighter and more hydrated skin by the end of the study
    • Those taking Dermial experienced a decrease in skin scaliness


    Meanwhile, participant satisfaction was 69%, with this proportion all stating they were either very satisfied or satisfied with the product. 


     


    Beauty benefits for all ages


    Alongside the measures discussed above, Bioiberica ran a sub-analysis of the study’s results, which suggest that Dermial could also offer different skin-supporting effects depending on a user’s age.


    Interestingly, participants older than 55 experienced significant improvements in biomarkers of skin barrier function — including brightness, hydration, smoothness, deformability, roughness, scaliness and temperature.


    Meanwhile, pH balance was also better maintained in the older group compared with the placebo, suggesting that Dermial can address age-related skin concerns, such as the appearance of wrinkles, dryness, dullness and roughness.


    “We are so excited to share the full details of this ground-breaking debut clinical trial, demonstrating the incredible potential Dermial holds for nutraceutical innovation,” comments Daniel Martínez-Puig, Head of R&D Human and Animal Health at Bioiberica and one of the study’s authors.


    “While overall improvements were less pronounced in volunteers younger than 55 years, they nevertheless experienced benefits in hydration, brightness and smoothness. These results point to the versatility of Dermial as a skin health supplement, able to meet consumers where they are in their skin health journey, regardless of age.”


     


    Reference


    Oral Supplementation with a New Hyaluronic Acid Matrix Ingredient Improves Skin Brightness, Hydration, Smoothness, and Roughness: Results from a Randomized, Double-Blinded, Placebo-Controlled Study

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  • London Pulse win the Netball Super League Grand Final for the First Time Ever

    London Pulse win the Netball Super League Grand Final for the First Time Ever

    London Pulse won their first ever Netball Super League (NSL) Grand Final this weekend at the O2 Arena, London, live and on demand for the international netball family on NetballPass.

    Pulse, who finished top of the ladder this season and won the pre-season Super Cup, faced defending Champions Loughborough Lightning in front of the biggest NSL Grand Final crowd ever.

    An end-to-end frantic start to the game made it hard to see who was going to come out on top, but once Pulse found their rhythm there was no stopping them.

    England Rose Funmi Fadoju lead the Pulse defensive end as she has all season, making eight deflections, three interceptions and eight gains – a performance she was later awarded Player of the Match for.

    The defensive work of Fadoju, and fellow international and domestic league teammates, Halimat Adoi and Zara Everitt, knocked Lightning and broke down their attacking flow which Pulse were able to capitalise on ensuring they always kept their opposition at arm’s length.

    There were later two Everitt’s on court for a period of time, as Zara’s sister, Darcey Everitt replaced an injured Adio in defence – despite the forced change, Pulse still did not miss a beat.

    Lightning on the other hand had their lowest scoring game of the season, scoring just 45 goals to Pulses 53.

    Pulse became the 7th different team to be crowned NSL Champions, and the first of the new era.                                                 

    One of their players also broke a record of her own, with the introduction of Gracie Smith as a substitute in the match making her the youngest ever player, aged just 16, to feature in a NSL Grand Final.

    You can catch up on the Grand Final on NetballPass, here. *

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  • How Xbox’s Game Pass policies is signalling the doom for the AAA industry | Esports News

    How Xbox’s Game Pass policies is signalling the doom for the AAA industry | Esports News

    Microsoft Xbox Game Pass provides gamers with unprecedented access to hundreds of titles for a very minimal monthly fee. Yet beneath its player-friendly model, as suggested and warned by industry leaders, there’s a gathering storm. This storm as per them, threatens blockbuster game development’s very foundation.Be it unsustainable developer payout or cannibalising sales, Xbox Game Pass, as per reports, is setting a dangerous precedent. The subscription giant and its strategy, as argued, are quietly undermining the AAA ecosystem’s economic pillars, forcing a reckoning that the industry might not survive without being unscathed.

    Game Pass policies have an unsustainable core

    At the heart of this entire crisis is Game Pass’s fundamental economics. As argued by Industry veterans, Microsoft leverages vast resources for subsidizing services. It creates an artificially lower price point. The model, as contended by critics, distorts market value—artificial market conditions created with traditional sales struggling to compete.

    Xbox Dev BLASTS Xbox Game Pass: “This Model DESTROYS Studios”

    Ex-founder of Arkane Studios, Raphael Colantonio, bluntly labelled Game Pass as unsustainable. As per his assertions, it “progressively harmed” the gaming industry for over a decade now, and it survives on corporate subsidies instead of genuine value. He further added that it’s propped by Microsoft’s “infinite money”. It is feared that Microsoft will persist until all alternative business models are crushed. It will leave all developers with a very limited choice.

    Xbox Game Pass for Developers Acts as Double-Edged Sword

    Microsoft’s subscription model promises guaranteed payouts and exposure for developers. But as revealed, Game Pass instead devalues games, conditioning players to expect content for just “free” under their subscription. Probably this was the reason why some major AAA titles, including Monster Hunter Wilds, Kingdom Come: Deliverance II, and Civilisation VII, avoided Xbox Play Anywhere, which is meant to unify the platform.Even Towerborne, the Xbox-published game, chose to launch its early access on Steam and not Xbox. That’s a sign of some internal doubts about the health of the Xbox platform.While smaller studios benefit from all upfront payments, AAA developers face a huge dilemma. If some major titles launch on Game Pass, the standalone sales of the game plummet. Despite Microsoft compensating them, in the long term, this model discourages purchases made at full price. It shrinks revenue streams while funding big-budget games. It even fails to attract Indies or AAA developers.

    Cannibalized sales create a devastating impact

    To understand the above-said better, when a game makes its debut on Game Pass, players do not need to buy it outright. While Microsoft does pay off developers for offsetting losses, it doesn’t replace the traditional sales value that could have been otherwise generated. As said, or rather warned by Michael Douse, Larian Studios’ publishing director, ‘infinite money doesn’t make sense forever.’

    The AAA Gaming Industry Just Got Destroyed From The Inside

    With evidence suggesting that Game Pass cannibalizes traditional sales, particularly on the Xbox platform, there are many who are now raising their voices against it. As per Industry journalist Christopher Dring, games that are launched on Game Pass can easily be expected to lose around 80% of the expected Xbox premium sales.Taking an example of Starfield, its inclusion within Game Pass boosted subscriber members. However, it likely slashed its direct sales. Even Hellblade 2 and Indiana Jones and the Great Circle underperformed in their full-priced Xbox sales. While Microsoft might not have directly blamed it on Game Pass, the correlation here is just undeniable.Even players start to gravitate to “free” access through subscription and bypass outright purchases. Such correlation is not coincidental, but it is structural. When any major release lands on the Xbox Game Pass, buying it becomes redundant. Now, if this starts to become a new norm, studios, especially AAA studios, might struggle to justify massive budgets. This will lead to a few AAA risks and a high reliance on Microsoft’s funding.

    Xbox Game Pass offers a false lifeline to smaller studios

    Proponents quite often highlight that Game Pass does act as a boon to smaller developers and all the risky new IPs. Douse acknowledges this potential. As noted by him, it could derisk those smaller teams’ launch, which face uncertain markets, but what exactly would happen when all the money runs out?

    Is Xbox Game Pass BAD for Developers?

    The current model is reliant on continuous and massive investments made by Microsoft to secure content. However, if funding shifts or slows down, the safety net for smaller studios would vanish overnight. It would leave them exposed, without any security for the creative risks.

    Game Pass: Destroying Gaming? Indie Devs Reveal Shocking Truth!

    But wait, there’s more beyond money running out. Game Pass, which initially was praised to help Indie games reach a wide audience, isn’t the same anymore. With growing services, smaller titles are at higher risk of getting buried within an oversaturated catalogue. Unlike Steam, where the games remain purchasable quite indefinitely, Game Pass keeps rotating titles in and out. It leaves developers scrambling for needed visibility.Even some successful indies are now facing a catch-22—Microsoft’s short-term payouts vs. Long-term sustainability. If the players do not buy outside the subscriptions, Indies would lose leverage over pricing and discoverability at the same time.

    Player Advantage vs Developer Disadvantage

    Why Xbox Game Pass Ultimate is Still the Best Deal

    For the players, Game Pass is quite an undeniably phenomenal deal. It gives instant access to a vast library that includes all major releases. With day-one access to the content, there’s an incredible value for players. It democratizes gaming. It makes AAA experiences affordable for those who might not otherwise participate in them. But what about AAA studios? They get forced to profit outside the subscriptions, and for it, they would either cut budgets or shift to live-service models, to sustain revenue.

    Is XBOX Game Pass Bad for Developers?

    For developers, especially those who are behind those large-budgeted AAA games, the entire picture is more grim. Xbox Game Pass subscription model devalues individual titles. Players who are accustomed to the lower monthly fee just become resistant to paying $70 for a purchase. This creates a shift in revenue stream from direct sales to those opaque subscription payouts as per engagement metrics. It creates huge financial uncertainty that is lethal for the AAA industry, especially for studios that invest $200M+ in projects.It is due to this that Colantonio has suggested Game Pass to keep its focus on back-catalogue titles and not day-one releases. It will help preserve sales for the newer games while still continuing to offer value. But will Game Pass do so? Only time can tell about it.

    Escalating situation seeks balance before the bubble bursts

    The industry is not calling for the demise of Game Pass, but it wishes for a critical reassessment. Colantonio and many others have already suggested a sustainable path for it—Game Pass must primarily function as the back-catalogue service and not the day-one AAA release platform. It will help preserve the value proposition for the players. It will also protect the economic model, which is required to fund ambitious and new projects.The current trajectory that’s been fueled by deep pockets of Microsoft risks creating a market where only subscription giants could survive. Without bringing in an urgent policy adjustment or a fundamental shift within the Game Pass model, the ability to fund next-generation, groundbreaking AAA experiences faces existential peril. So, in short, the time for a balance is right now.

    What will the AAA industry be without this balance?

    WILL XBOX GAME PASS LAST? Pros & Cons of Microsoft’s Game Pass

    The gaming industry today is at a crossroads. If the Game Pass continues to dominate, the world will see fewer big-budget single-player games, which will also be riskier without a direct sales line. There will also be more live-service and microtransactions models for offsetting lost revenue. Additionally, with increased consolidations of studios under Microsoft, competition will be reduced.The solution is therefore simple. There’s a need for a balanced approach. Subscriptions must complement, instead of replacing, the traditional sales. Otherwise, Xbox Game Pass might accelerate the decline of AAA games, on which it relies.


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  • UniCredit, BPM shares up on report Italy will have to drop merger conditions – Reuters

    1. UniCredit, BPM shares up on report Italy will have to drop merger conditions  Reuters
    2. Ops Unicredit on Banco Bpm: Wednesday 9 July the moment of truth with the ruling of the TAR on…  firstonline.info
    3. Banco BPM jumps after media report EU ready to warn Italy on UniCredit bid  TradingView
    4. UniCredit-Banco BPM Deal: A Regulatory Crossroads for European Banking  AInvest
    5. Unicredit: “Golden power su ops Banco Bpm ambiguo, rischiamo pesanti sanzioni”. Via libera per …  firstonline.info

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  • Iran receives Chinese surface-to-air missile batteries

    Iran receives Chinese surface-to-air missile batteries

    The deliveries of Chinese surface-to-air missile batteries occurred after a de-facto truce was struck between Iran and Israel on 24 June, an Arab official familiar with the intelligence told MEE.

    Another Arab official, who spoke on the condition of anonymity to discuss the sensitive intelligence, said that the US’s Arab allies were aware of Tehran’s efforts to “back up and reinforce” its air defences and that the White House had been informed of Iran’s progress. 

    The officials did not say how many surface-to-air missiles, or SAMs, Iran had received from China since the end of the fighting. However, one of the Arab officials said that Iran was paying for the SAMs with oil shipments.

    China is the largest importer of Iranian oil, and the US Energy Information Administration suggested in a report in May that nearly 90 percent of Iran’s crude and condensate exports flow to Beijing.

    For several years, China has imported record amounts of Iranian oil despite US sanctions, using countries such as Malaysia as a transshipment hub to mask the crude’s origin.

    “The Iranians engage in creative ways of trading,” the second Arab official told MEE.

    MNA/

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  • Australian scientists develop “biological AI” system to speed drug discovery-Xinhua

    SYDNEY, July 8 (Xinhua) — Australian scientists have unveiled a pioneering “biological artificial intelligence (AI)” platform designed to dramatically accelerate drug discovery.

    The innovative system enabled the rapid creation and evolution of molecules with new or enhanced functions directly inside mammalian cells, paving the way for more effective gene therapies and advanced medicines, according to a statement released recently by the University of Sydney, which led the study.

    Called PROTEUS (PROTein Evolution Using Selection), the platform marked a major leap in molecular engineering by enabling rapid evolution of proteins within mammalian cells, something previously limited to bacteria, which allowed scientists to mimic and speed up natural selection, reducing processes that once took years to just weeks, researchers said.

    “What is new about our work is that directed evolution primarily works in bacterial cells, whereas PROTEUS can evolve molecules in mammal cells,” said the study’s co-senior author Greg Neely from the University of Sydney.

    Led by the University of Sydney’s Charles Perkins Center and the Centenary Institute, the research has made PROTEUS open source, enabling global adoption to speed the development of advanced enzymes, molecular tools, therapeutics, and improved gene-editing and mRNA medicines.

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  • PM Calls Of Comprehensive Action Plan To Boost Agri Production – UrduPoint

    1. PM Calls Of Comprehensive Action Plan To Boost Agri Production  UrduPoint
    2. Pakistan to deploy AI, global experts in push to modernize agriculture  Arab News
    3. Prime Minister Muhammad Shehbaz Sharif chairs a meeting regarding matters pertaining to the Agriculture sector  Associated Press of Pakistan
    4. PM Shehbaz calls for urgent action plan to boost farm output, reforms, and climate resilience  Profit by Pakistan Today
    5. Enhancing agricultural productivity Govt’s top priority: PM Shehbaz  SUCH TV

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  • Syria – Wildfires (DG ECHO, JRC GWIS, SARD, media) (ECHO Daily Flash of 8 July 2025) – ReliefWeb

    1. Syria – Wildfires (DG ECHO, JRC GWIS, SARD, media) (ECHO Daily Flash of 8 July 2025)  ReliefWeb
    2. Syria appeals to EU for help battling massive wildfires in Latakia  Euronews.com
    3. DAA affirms readiness to provide support in extinguishing coastal fires  وكالة هاوار للأنباء
    4. Reforestation and Afforestation campaign in latakia to restore forests in Latakia – Syrian Arab News Agency  الوكالة العربية السورية للأنباء
    5. Jordanian helicopters continue to help Syria in containing wildfires for 6th day  Arab News

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  • Nearly half a million Afghans return from Iran after crackdown | Refugees News

    Nearly half a million Afghans return from Iran after crackdown | Refugees News

    Nearly 450,000 Afghans have returned from Iran since early June, according to the United Nations refugee agency, after Tehran imposed a July 6 deadline for undocumented migrants and refugees to leave the country.

    The surge compounds Afghanistan’s existing challenges as the impoverished nation struggles to integrate waves of returnees from Pakistan and Iran since 2023, amid one of the world’s worst humanitarian crises after decades of conflict.

    The UNHCR reports that more than 1.4 million people have “returned or been forced to return to Afghanistan” this year alone. Iran’s late May directive potentially affects four million undocumented Afghans among the approximately six million Afghan residents claimed by Tehran.

    Border crossings increased dramatically from mid-June, with some days seeing approximately 40,000 people entering Afghanistan. Between June 1 and July 5, 449,218 Afghans returned from Iran, bringing the 2024 total to 906,326, according to an International Organization for Migration spokesman.

    Many returnees report experiencing pressure from authorities, arrests, deportations, and financial losses due to hasty departures. The crisis response has been hampered by significant cuts in foreign aid, prompting calls for increased funding from the UN, international NGOs, and Taliban officials.

    The UN has cautioned that this mass return could further destabilise Afghanistan, which already faces entrenched poverty, unemployment, and climate change effects. “Forcing or pressuring Afghans to return risks further instability in the region, and onward movement towards Europe,” the UNHCR said on Friday.

    While Taliban officials advocate for a “dignified” return process, Iranian media frequently reports mass arrests of “illegal” Afghans. Iran’s deputy interior minister, Ali Akbar Pourjamshidian, acknowledged that while undocumented Afghans in the country were “respected neighbours and brothers in faith”, Iran’s “capacities also have limits”. He indicated the return process “will be implemented gradually”.

    Many Afghans had migrated to Iran for employment, sending vital remittances to families in Afghanistan. Returnee Ahmad Mohammadi told the AFP news agency at a reception centre in Herat province, “If I can find a job here that covers our daily expenses, I’ll stay here. But if that’s not possible, we’ll be forced to go to Iran again, or Pakistan, or some other country.”

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  • WOC 2025: Qualification kicked off the championships in Finland

    WOC 2025: Qualification kicked off the championships in Finland

    The World Orienteering Championships in Finland kicked off on Tuesday morning with the qualification for Wednesday’s middle distance.

    Here, the athletes were divided into three heats per gender with the goal of finishing in the top 15 to qualify for the final.

    And from the start, they were thrown into demanding Finnish terrain in the race, which was held right across from the WOC event center in Tahko.

    An challenging area with many details and many short legs made up the first part of the courses, which today was 3.3 kilometers for women and 3.9 kilometers for men before ending down a ski slope at the finish area.

    The women’s heat winners in today’s qualification were Natalia Gemperle (SUI), Simona Aebersold (SUI) and home favorite Venla Harju.

    On the men’s side, the Swiss were also strong. Here, the reigning middle distance world champion Matthias Kyburz was fastest in heat 1, while Fabian Aebersold (SUI) and Kasper Fosser (NOR) won the other heats.

    Find results, GPS-tracking and the livestream from today’s qualification in IOF LIVE.


    Timo Sild (EST) was third in heat 1 today. By Kristina Lindgren

    Wednesday’s Middle distance final takes place in Neulamäki close to the host city Kuopio.

    The first start is at 13:40 EEST (UTC +3) and the TV broadcast begins at 14:30 and runs until 18:20.

    Find all you need to follow the Middle final in IOF LIVE

    Reigning middle distance World Champions from Switzerland two years ago are Tove Alexandersson (SWE) and Matthias Kyburz (SUI).

    Watch the WOC 2023 Middle distance in YouTube here

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