Author: admin

  • Holloway wins UFC 318 main event in Poirier’s retirement fight

    Holloway wins UFC 318 main event in Poirier’s retirement fight

    NEW ORLEANS — Dustin Poirier couldn’t secure a win in the final fight of his storied UFC career on Saturday — but ultimately, that mattered very little.

    Poirier’s final walk to the Octagon at UFC 318 inside the Smoothie King Center ended in a unanimous decision loss to former featherweight champion Max Holloway, but it was still a fitting end to his 16-year professional career. The five-round BMF title fight saw several dramatic swings of momentum and culminated in the two meeting in the middle of Holloway’s patented point-down exchange.

    All three judges scored the lightweight bout for Holloway: 49-46, 49-46 and 48-47. Immediately after the win, Holloway (27-8) welcomed all BMF challengers and made a brief reference to 155-pound champion Ilia Topuria before ceding the spotlight to Poirier (30-10).

    “It’s been overwhelming honestly,” Poirier said about the amount of fight-week adoration he received. “I feel appreciated. I feel seen. I never stepped outside of fighting and looked at it this way. I never got to look at it third person. This week has been incredible. I feel loved by the fans, Louisiana and the company. I’m a kid living the dream out here, man, throwing punches.”

    Poirier, 36, retires in a tie for the fifth-most wins in UFC history with 22. He is also tied for fourth-most knockouts with 11.

    Poirier’s legacy involves three undisputed title appearances in 2019, 2021 and 2024. He came up short in each, against Khabib Nurmagomedov, Charles Oliveira and Islam Makhachev. He captured an interim lightweight title in 2019, though, by defeating Holloway via unanimous decision in an instant five-round classic.

    Saturday’s trilogy against Holloway — Poirier won the first two meetings — featured everything the sport came to expect from a Poirier fight. Holloway dropped him with a right hand in the opening minutes, but Poirier survived and scrambled back to his feet. Holloway dropped him again in the second round, but Poirier recovered and actually dropped Holloway later in the frame and shot for a guillotine.

    Poirier walked out to the Octagon with New Orleans rapper Lil Wayne, in a poetic nod — Poirier, who was born and raised in Lafayette, walked out to Lil Wayne’s track “A Milli” for his UFC debut in 2011. The UFC rearranged its schedule to book Poirier’s final fight in his home state.

    According to UFC Stats, Holloway, of Hawaii, outlanded Poirier in total strikes 186-114. Poirier cut Holloway under his left eye in the fourth round, but the volume of Holloway’s strikes also started to take a toll on him around that same time. His movements grew a little sluggish late, although he still had enough to accept Holloway’s invitation to stand in the center of the Octagon and swing at the end of the fight.

    It’s a big win for Holloway, who came off the first knockout loss of his career to Topuria in their 145-pound title fight last October.

    Continue Reading

  • Watford FC helps to plant trees with kit sales

    Watford FC helps to plant trees with kit sales

    Louise Parry

    BBC News, Hertfordshire

    Watford FC Two young women stand in the countryside on a grass track under some large trees. They wear the new Watford away shirt which is a dark forest green with lighter green checks. They smile at the camera and both have long straight fair hair. It is a sunny day.Watford FC

    Watford FC, which has unveiled its new away kit, aims to cut its carbon emissions in half by 2030

    A football club is joining a campaign to plant trees by donating money from shirt sales.

    Championship side Watford FC has unveiled its new 2025/26 away kit, which is made from recycled polyester.

    The club will donate 50p from every away shirt sale to Your Tree Our Future – a free tree giveaway programme in Hertfordshire.

    Run by the county and borough councils, the project aimed to get 1.8 million new trees planted by 2030.

    In the past four years, 191,000 trees have been planted in Hertfordshire in places including gardens and schools.

    In Watford alone, 5,000 trees were handed out to residents this year, taking the total over the whole scheme to 13,000.

    The away shirt is aptly coloured forest green, and matches the kit’s black shorts and green socks.

    Fans can choose to buy tops without the branding of a local gambling company, although, on the pitch, players’ shirts will feature the sponsor’s logo.

    Watford FC A young man wearing the new Watford away shirt and giving a huge smile, looking very energised. He is standing against a black background.Watford FC

    Fifty pence from the sale of each away shirt will go towards the tree planting project in Hertfordshire

    Tarang Panchal, head of procurement and sustainability at the club, said: “We have an ambition to be one of the most sustainable, green football clubs in the UK, and the launch of our away kit is very much aligned with this vision.”

    He said the recycled polyester kit and tree planting pledge were “part of a development plan with short, medium and long-term goals”.

    He added: “For example, we recently partnered with The Wildlife Trust, an organisation that would help us to develop the training ground from a biodiversity and ecological point of view.”

    Ian Stotesbury, a Liberal Democrat councillor with a responsibility for sustainability at Watford Borough Council, said: “Watford FC continues to lead by example – aiming for net zero by 2040 and a 50% carbon cut by 2030.

    “Linking their new away kit sales to the Your Tree Our Future programme also supports Watford’s ambition to be a carbon-neutral town by 2030.

    “Trees help absorb carbon and clean the air, making a real difference to our environment.

    “All the club does for the community highlights why they are the original family club,” he said.

    Continue Reading

  • Al Futtaim Retail to Buy $666 Million Stake in Cenomi Retail

    Al Futtaim Retail to Buy $666 Million Stake in Cenomi Retail

    Al Futtaim Retail has agreed to buy a major stake in Saudi Arabian firm Cenomi Retail for 2.5 billion riyals ($666 million).

    The United Arab Emirates-based firm plans to purchase 49.95% of the share capital of Cenomi Retail from shareholders including Saudi FAS Holding Company and FAS Real Estate Company, according to a statementBloomberg Terminal on Sunday.

    Continue Reading

  • What is Baby Grok? Elon Musk announces kids-friendly AI app after controvery over sexualized AI avatar – Mint

    1. What is Baby Grok? Elon Musk announces kids-friendly AI app after controvery over sexualized AI avatar  Mint
    2. Elon Musk announces Baby Grok AI chatbot designed specifically for children’s learning needs  Fox Business
    3. Meet Baby Grok @xAI: A Safe, Smart, and Fun App for Kids Everywhere  Vocal
    4. Musk’s xAI to roll out Baby Grok inspired by Marvel’s Baby Groot | xAI had apologised for antisemitic Grok posts | Inshorts  Inshorts
    5. Elon Musk to launch child-friendly ‘Baby Grok’ after his ‘social media is bad’ warning to kids; netizens ask is it free?  Mint

    Continue Reading

  • Eating eggs linked to less buildup of toxic proteins

    Eating eggs linked to less buildup of toxic proteins

    Share on Pinterest
    Eating eggs regularly is linked to less buildup of toxic proteins in brain, according to a study on human brains. Image credit: Ingrid Bertens/Stocksy
    • A study finds that eating eggs is associated with a reduced risk of developing Alzheimer’s disease.
    • Using brain autopsies, the scientists also showed that those who ate eggs more regularly had less protein buildup in the brain associated with Alzheimer’s.
    • The researchers conclude that this link may be due to eggs’ choline and omega-3 content.

    Eggs have been a dietary staple since before humans evolved to be humans. Although they are packed with nutrients, relatively cost-effective, and easy to source, they have been the subject of much controversy in the health and wellness domain over the years.

    According to the authors, eating one egg per week was associated with a 47% reduction in Alzheimer’s risk compared with eating eggs less than once each month.

    They also showed that those eating eggs had a reduced buildup of the toxic proteins associated with Alzheimer’s.

    Before we get into the details, we should mention that some of the authors received funding from the Egg Nutrition Center, “the science and nutrition education division of the American Egg Board.”

    Are eggs good for you or bad for you? One hundred years ago, and for thousands of years before that, eggs were considered essential. Nutrient-dense and rich in protein and micronutrients, eggs were a staple throughout the world.

    However, as nutrition science progressed, it became clear that dietary cholesterol did not significantly impact blood levels of cholesterol.

    Thanks to this new understanding, and a healthy dose of research funding from the Egg Nutrition Center, eggs were edged slowly back into play.

    Their saturated fat content, though, is still a concern, so eggs are still partially sidelined. Still, they are likely much healthier than many of the low-fat, highly processed snacks that have replaced eggs in modern kitchens. In fact, eggs contain all essential trace elements.

    Today, most nutritionists and associated experts have a relatively neutral view of eggs. In general, the advice is that they can form a part of a healthy, well-balanced diet, but at the same time, eating multiple eggs per day could be unhealthy.

    Alzheimer’s is the most common form of dementia, and despite decades of research, there is no cure, and treatments that can slow the disease are severely lacking.

    For that reason, understanding the lifestyle factors associated with increased risk is essential. In this vein, many scientists are focusing on dietary influences.

    Previous research has shown that choline is important for cognitive function. It has also identified a potential link between moderate choline intake and a reduced risk of dementia. As the authors of the latest study explain, eggs are the “top food source” of choline, so they are worth investigating.

    Choline has many important functions; for instance, it is a precursor to the neurotransmitter acetylcholine, plays a pivotal role in cell membranes, and has neuroprotective powers.

    Also, as the authors explain, “choline modulates the expression of key genes related to memory, learning, and cognitive functions via epigenetic mechanisms.”

    Although our body can synthesise choline, it cannot synthesize enough to meet all the body’s needs, so some must be taken in with our diet.

    These facts led the authors of the new study to investigate links between egg consumption and Alzheimer’s risk.

    The recent study included data from 1,024 older adults with an average age of 81.4. All participants lived in retirement communities and residential facilities in Illinois.

    They attended yearly checkups and completed food frequency questionnaires, and the researchers followed them for an average of 6.7 years.

    During this time, a little over one-quarter of them developed Alzheimer’s disease.

    After analysis, the scientists found that individuals who consumed at least one egg per week had a 47% reduced risk of developing Alzheimer’s during follow-up compared with those eating one egg per month or fewer.

    In the second part of their study, they looked at the post-mortem brains of 578 participants. They found that those who ate one or more eggs each week were more likely to have less Alzheimer’s-associated protein buildup.

    Overall, the authors suggest that consuming at least one egg per week may help reduce the risk of Alzheimer’s. They explain that the choline and omega-3s in eggs might have a “synergistic” effect, whereby they join forces to protect brain health during aging.

    Medical News Today spoke to Christopher U. Missling, PhD, president and CEO of Anavex Life Sciences, who was not involved in the study. Missling explained that:

    “About 39–40% of the protective effect was explained by higher dietary choline intake. Egg yolks also contain omega-3 fatty acids, which have known neuroprotective properties. The combination of choline and omega-3s may be particularly beneficial for brain health.”

    The study authors also point to previous research demonstrating that people with Alzheimer’s are more likely to be deficient in omega-3s and choline.

    Overall, the scientists conclude that, “once replicated in other prospective cohorts and confirmed by clinical trials, these findings may have important public health implications for reducing the population’s risk of [Alzheimer’s].”

    If the results are replicated, this could be a very useful, low-cost intervention. MNT also spokle with Maddie Gallivan, RD, a registered dietitian who was likewise not involved in the recent study.

    “Eggs are often a go-to food for older adults, as they’re soft in texture, which can be helpful for those with dentures, quick to prepare, and packed with key nutrients,” Gallivan explained. “So it’s great to see a study focussing on how they may support cognitive health in later life.”

    However, the study does have certain limitations. For instance, they only had a relatively short follow-up — just 6.7 years. This, as the authors explain, increases the risk of reverse causality.

    “The study population consisted of older adults from the Rush Memory and Aging Project, a specific U.S.-based cohort,” Missling told MNT. “The findings may not generalize to younger populations or those from different cultural or dietary backgrounds.”

    He also reminded us that “dietary intake was assessed through self-reported food frequency questionnaires, which are subject to recall bias and inaccuracies.” So, participants may not have accurately reported or remembered their egg consumption.

    “It’s important to remember that no single food acts in isolation,” Gallivan told us, “and it’s our overall dietary pattern that really counts. A varied, nutrient-dense diet rich in whole foods is key to supporting brain health and reducing dementia risk.”

    For now, if you like eggs, enjoy them. They may reduce your dementia risk, but if not, they will certainly provide you with a good dose of protein and a healthy range of micronutrients.

    Continue Reading

  • Ex-Olympic cyclist Emma Pooley on the pressures of diet

    Ex-Olympic cyclist Emma Pooley on the pressures of diet

    Former Olympic cyclist Emma Pooley has spoken about how her relationship with food was coloured by the idea that cyclists should be thin and to her food was not “joyful”.

    Pooley, 42, grew up in Norwich and studied mathematics and engineering at Cambridge University, only coming to cycling in her 20s after a running injury.

    The triple Olympian and five-time world champion, retired from professional road cycling in 2014.

    She has released a book telling her story and sharing her favourite recipes, and said: “My point is that enjoyment is a really big part of healthiness.”

    Looking back on her time as a champion cyclist, Pooley said: “At the elite level, the idea that thinner is faster is wrong… and I think it’s quite damaging.

    “I had some problems in the sport but.. I’m fine now and I wasn’t that bad.

    “But I know other athletes have had problems and it affects your health long-term, so it is something I’m concerned about.”

    She said she addressed those issues in her book and said it was important that the sport “gives a healthy impression on the viewers as well, so that it should inspire people to cycle”.

    Some of her recipes were meals she “learned to make to support my training, but now I eat as part of a healthy lifestyle”.

    However, she said attitudes had “changed for the better and there was a lot of really well-founded science-based thinking in cycling and other sports about a balanced diet and a healthy body”.

    “Some people are naturally very slim and some aren’t and you can’t force everybody to look the same,” Pooley said.

    “No-one forced calorie restriction upon me, it was because I was told it was better to be thin and I looked around me and saw lots of thin people so I inflicted it upon myself, but I realised… the more I ate the faster I went.

    “Now I realise that I was over-restricting and so a lot of people realise it’s not about restriction, it’s about healthy fuel.

    “My point is that enjoyment is a really big part of… healthiness.”

    Continue Reading

  • Why NimbleEdge Is Betting Big On Open Source AI

    Why NimbleEdge Is Betting Big On Open Source AI

    As regulatory compliance and data security concerns take centre stage, conversations around AI and GenAI are moving towards a more transparent open source system. According to the World Economic Forum, open source AI development offers three key advantages. It accelerates innovation while maintaining product safety, makes models more reliable, as datasets and codes are thoroughly audited, and significantly lowers time to market and development costs. 

    Conversely, closed-source models such as the PaLM (Pathways Language Model, a family of large language models developed by Google), most of the OpenAI GPT models, or Claude, an advanced language model by Anthropic, evade audits because these are not publicly available for developers to use. Besides, the data in use is organisation-specific, which is a practice that raises questions about the responsible use of AI.

    India might have missed the bus when the open source initiative (OSI) first made a foray in the late 1990s and the first decade of the new millennium. But today, tech entrepreneurs have started building open source AI models and platforms for new applications and better data security. It is a timely push towards ‘Sovereign AI’, boosting the country’s ability to develop, deploy and control AI-related intellectual properties in tune with its priorities.

    Take, for instance, NimbleEdge, a San Francisco- and Bengaluru-based AI startup set up in 2021 by AI researcher Varun Khare. It has recently launched DeliteAI, a full-stack and production-ready on-device agentic AI platform, enabling developers to build, deploy and run scalable and privacy-first AI-native solutions directly on smartphones. Additionally, there is a dedicated marketplace to find and integrate pre-built AI agents with applications. NimbleEdge has also introduced an on-device conversational AI assistant with built-in productivity features (more on its technology later).

    In an AI era dominated by cloud-based LLMs (large language models) and big tech companies wresting control of global user data, NimbleEdge is making a contrarian play by bringing AI model development to consumer devices to empower companies, developers and users. It is a move away from the mainframe (think of the massive shift from desktops to laptops and handhelds) for better operations, greater control and stringent privacy levels.

    Ditching the traditional cloud infrastructure is a case in point. It counters the limitations of cloud-based AI, which requires constant connectivity, increases latency and incurs high operational costs. Furthermore, developers will own the entire stack — everything from models to intelligence integration — enabling unique, AI-powered user experiences. Better still, when data is processed locally on the hardware in use, it enhances data security and user privacy.        

    “AI is the electricity of our generation. When we remove all the hype, it is still a fundamental shift in technology. This essentially means three things: Scaling beyond what the current cloud can do because the cloud infrastructure in India is very limited compared to the smartphone infrastructure. Again, AI must be personal and adapt quickly as the use of technology varies vastly among different generations. More importantly, it has to be private and secure,” said cofounder and CTO Neeraj Poddar, who joined Khare in 2024.

    Why Edge AI Forms The Core Of NimbleEdge

    Before we delve deeper into the tech components of DeliteAI and their benefits, it is essential to understand the tech philosophy behind shifting the mainframe, introduced by NimbleEdge. Unlike traditional AI, which relies on cloud-based backend systems to process data, Edge AI is all about building AI algorithms and models directly on connected devices located at the ‘edge’ of the network, closer to the data source, instead of relying on central cloud servers or remote data centres for processing. 

    This is, undoubtedly, a paradigm shift, as computation happens on the hardware itself (smartphones or other IoT devices) or a nearby Edge server. This decentralised approach allows devices to collect data, analyse it and make real-time decisions using built-in machine learning (ML) models. 

    Simply put, NimbleEdge is working at the intersection of data technology, artificial intelligence, and the collective intelligence of billions of tech enthusiasts keen to build personalised AI models. In doing so, it is eliminating the traditional dependency on cloud or high-end GPUs (graphic processing units) and ushering in a whole new architecture aligned with the power of smartphones.       

    Khare seems quite confident about the outcome. Elsewhere, in an interaction, he said that NimbleEdge could run 100 Mn AI models personalised for 100 Mn users.   

    But first things first. Khare, a graduate in computer science from IIT Kanpur, joined the University of California at Berkeley in 2020 for his research and started working with Professor Dawn Song, an AI and privacy advisor to the US Congress. Under her guidance, he realised the profound impact of AI when placed in human hands. Soon enough, he started leading the on-device training team at OpenMined, one of the biggest communities developing privacy-first infrastructure around AI and ML.

    The startup’s first major offering was an SDK (software development kit) for AI-powered app development. Within the first two years, its early versions reached more than 30 Mn devices, as NimbleEdge partnered with some of the biggest ecommerce and fantasy sports platforms. However, it declined to reveal customers’ names, citing non-disclosure agreements.

    Last year, Khare was joined by Neeraj Poddar, a seasoned entrepreneur with a decade of experience. Poddar’s first venture was Aspen Mesh, alongside an open source community that he built for about five years. Next, the duo focussed on two key areas — making the SDK an open source platform and launching a dedicated agent marketplace for developers. 

    Their efforts paid off, and DeliteAI was globally launched on July 10, 2025. 

    On the B2C front, NimbleEdge has developed an AI Assistant, which it claims to be an industry-first, fully on-device conversational AI assistant with built-in productivity capabilities. open source platform. In the past four years, the startup has partnered with Swiggy, SarvamAI, Meta, Qualcomm and several other industry leaders to develop its open source platform.

    A Deep Dive Into The Open Source Stack

    As discussed, the latest tech stack driving the DeliteAI platform includes a production-ready, open source SDK, an agent marketplace and the NimbleEdge AI voice assistant for end users.

    To begin with, the platform is natively built for smartphones (both Android and iOS), addresses many hardware constraints and bridges critical gaps such as the lack of unified tooling and standardised runtimes across the on-device AI ecosystem. 

    Its SDK is powered by an optimised inference engine, responsible for reasoning and decision-making, and an on-device Python runtime that manages agentic workflows using Python scripts. These components integrate seamlessly with industry-standard runtimes like ONNX and ExecuTorch, abstract away different mobile hardware and enable developers to create dynamic applications using familiar tools. The open source stack also ensures quick cross-platform deployment of LLMs, multimodal AI and transformer models without GPUs or cloud infrastructure. 

    On DeliteAI, workflows and models can be updated on the fly via a SaaS tool without releasing new apps. Again, user interactions are captured in real time, and intent-driven agents are activated for diverse use cases, from ecommerce to entertainment and grocery shopping.

    According to Poddar, no one has been able to run Python on phones until now, while integrating and orchestrating AI on phones remains a significant challenge.

    “Besides, our open source SDK will unlock a whole new experience for developers to enhance their applications. They can connect our on-device SDK to our SaaS platform, or link their custom SaaS platforms to update/change models or Python scripts. This will be a game-changer for our customers to explore innovation faster,” the CTO added.

    As DeliteAI is built for complete customisation and developer control, companies and individuals can bring their proprietary models and run inference directly on the device for enterprise-grade customisation. Processing everything locally ensures no data leaves the device, allowing organisations to fine-tune and deploy large language models and agents entirely offline.

    The Agent Marketplace at NimbleEdge provides a fast-growing library of plug-and-play AI agents for tasks like summarisation, recommendations and speech processing.

    Finally, there is the on-device, conversational AI assistant with built-in productivity use cases. But unlike proprietary assistants bound to a single ecosystem, NimbleEdge enables fully customised workflows and branded assistants, all powered by an open source, on-device platform without relying on external dependencies. 

    However, the startup faces stiff competition from global players like Apple’s Siri, Google Assistant, and a growing list of email summarisation and note-taking platforms like Fireflies and Fathom.

    Khare argues that Siri and Google Assistant struggle to scale as they require access to multiple applications, while many users are wary of sharing data.

    “In contrast, NimbleEdge integrates seamlessly with Slack, Gmail, phone voice recorders and other apps, without requiring users to send their data to third-party developers,” he explained.

    Can NimbleEdge Compete With Global Giants, Align With India’s AI Mission? 

    NimbleEdge has started generating revenue but has not disclosed its financials. But going forward, it will place its bets on a B2B subscription model as its primary revenue stream. Currently, customers are charged based on the number of devices using the application. For smaller apps with around 10K monthly active users, the cost per device is 20 cents per day. However, the pricing will change with the increasing integration of LLMs into these applications.

    Within the next 12 months, NimbleEdge expects to reach 100 Mn devices and a subsequent jump in revenue. But in spite of this business growth, its core focus will be expanding its open source community.

    There lies the crux. Unlocking the full potential of AI through on-device, open-source operations and scaling personalised models to deliver engaging experiences should be considered a leap forward. As Podder highlighted in a recent press statement: This is the missing infrastructure layer and developer tooling we longed for while building distributed systems at a global scale. Now, it’s accessible to everyone.

    Still, can it scale the open-source business fast enough to compete globally?

    The AI industry remains a fiercely competitive, proprietary space, where the adoption of open source solutions is far from widespread. Unlike China, where the OpenAtom Foundation — a non-profit formed in 2020 with support from major corporations and the Ministry of Civil Affairs — has been a catalyst for large-scale open-source AI projects, India has yet to establish a comprehensive policy.

    The rise of big tech companies like Microsoft, Meta, and Google in this space is another cause for concern. For instance, Microsoft created Open Neural Network Exchange (ONNX), and Meta developed PyTorch, a popular open-source machine learning library widely leveraged for R&D and product development. 

    NimbleEdge is not overly worried, though, saying it isn’t in direct competition with these tech giants. In fact, its platform is built on top of these frameworks. “Our objective is to efficiently run open source models like Llama (from Meta) on smartphones. We are also training some predictive models,” said founder-CEO Khare.

    Although the startup intends to develop proprietary models in the future, the founders kept the details under wraps. “Building this ecosystem starts with open source technology. We have already crafted a solid monetisation strategy and built a SaaS platform, which delivers new configurations and updates, tracks model performance, and improves user experience. We believe this business model will thrive,” said Poodar.

    Furthermore, the startup’s decentralised, privacy-first approach and data localisation policy may align with India’s sovereign AI mission. This will lead to new opportunities to contribute to a trusted, open source AI infrastructure.

    Given its primary focus on the US and India markets, it will be interesting to watch how NimbleEdge spearheads its efforts to shape a safer, more regulated AI landscape locally and globally.

    [Edited by Sanghamitra Mandal]


    Continue Reading

  • c2c trains are nationalised and return to public ownership

    c2c trains are nationalised and return to public ownership

    Lewis Adams

    BBC News, Essex

    Ben Schofield/BBC Heidi Alexander wearing a black blazer over a green T-shirt. She is smiling while standing on a train platform.Ben Schofield/BBC

    Transport Secretary Heidi Alexander said she wanted “excellent services” for passengers

    Rail services between south Essex and London have become publicly owned for the first time since the 20th century.

    Operator c2c, which runs services between Fenchurch Street and Shoeburyness, was nationalised on Sunday.

    It became part of Great British Railways, set up by the government to oversee the rail system in England, Wales and Scotland.

    Transport Secretary Heidi Alexander said passengers had been suffering “spiralling costs, fragmentation and waste”.

    Ministers have been allowed to take rail companies back into public ownership when their existing contracts expired.

    It was enabled under the Passenger Railway Services (Public Ownership) Act 2024, passed by Labour in November.

    On Sunday, c2c became the sixth operator to become nationalised.

    It would be followed by Greater Anglia, which runs trains throughout the East of England, on 12 October.

    c2c A white train with c2c printed on the side in pink. The train is parked next to a platform.c2c

    Services run by c2c are the first in the East of England to be nationalised

    Alexander said public ownership would tackle “deep-rooted problems” experienced on the railway.

    She added: “A unified network under Great British Railways will take this further with one railway under one brand with one mission: delivering excellent services for passengers wherever they travel.”

    The government hoped nationalisation of all services in Britain would bring savings of up to £150m, while also reducing delays and cancellations.

    David Burton-Sampson, the Labour MP for Southend West and Leigh, said it would bring a host of benefits for passengers.

    “What they will notice in the longer-term is a better service, a more consistent level of ticketing and hopefully a continued improvement in punctuality,” he added.

    However, shadow rail minister and Conservative Norfolk MP Jerome Mayhew previously said he feared nationalisation would end up costing taxpayers more money in increased costs for leasing rolling stock.

    He said the government was “risking” successful operations for “ideological reasons”.

    C2C rail services are renationalised

    Continue Reading

  • Ozempic and Wegovy may cut dementia risk by 45% and manage diabetes, study finds |

    Ozempic and Wegovy may cut dementia risk by 45% and manage diabetes, study finds |

    A groundbreaking study has revealed that GLP-1 receptor agonists—including popular weight-loss and diabetes drugs like Ozempic, Wegovy, and Mounjaro- may significantly reduce the risk of developing dementia. The analysis, conducted by Irish researchers and published in JAMA Neurology, involved data from over 164,000 participants and found that these medications reduced the risk of memory-robbing disorders by up to 45 per cent. These findings not only open new avenues for neurological protection but also position GLP-1 drugs as powerful tools in both metabolic and cognitive health management.

    Study links GLP-1 drugs like Ozempic and Mounjaro to lower dementia risk

    Researchers from the University of Galway reviewed 26 clinical trials involving 164,531 individuals—65% of whom were men, with an average age of 64. The participants were followed for an average of 31 months. The key discovery: patients taking GLP-1 agonists such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) were 45% less likely to develop dementia compared to those on other glucose-lowering medications.Dr. Catriona Reddin, senior study author, said, “Our findings suggest that GLP-1 receptor agonists, in particular, may have a protective effect on brain health.”

    How GLP-1 agonists may protect against dementia

    Although the exact mechanism remains under investigation, researchers propose several pathways through which GLP-1 medications could shield the brain:Reduced neuroinflammation: These drugs may lower inflammation in the brain, which is known to damage neurons and trigger dementia symptoms.Decrease in amyloid and tau proteins: GLP-1 agonists could suppress the accumulation of toxic proteins linked to Alzheimer’s disease.Improved blood vessel health: They may reduce blood pressure and enhance blood flow, preventing vascular dementia.Neurogenesis stimulation: Early research suggests these drugs may promote neural growth in the hippocampus, the brain region essential for memory.

    GLP-1 drugs may help prevent both diabetes and dementia

    The new study aligns with earlier research from the University of Florida, which followed 400,000 Americans and reported a 33% lower risk of dementia among GLP-1 users compared to other treatments. This growing body of evidence supports the role of semaglutide and tirzepatide not only in treating type 2 diabetes and obesity but potentially in preventing cognitive decline.Professor Martin O’Donnell, Dean at the University of Galway, emphasised, “With both diabetes and dementia rising, these findings have major public health implications.”

    Dementia

    Dementia and diabetes: Twin epidemics in the US

    The study arrives amid alarming trends:

    • Over 8 million Americans currently live with dementia, with 500,000 new cases diagnosed each year.
    • Diabetes now affects 38 million people in the US; around 12% of the population.

    According to the Alzheimer’s Association, Alzheimer’s rates have climbed 25 consecutive years.The intersection of these two epidemics highlights the urgency of therapies that can address both conditions simultaneously.

    Diabetes management

    Study highlights need for more GLP-1 brain health data

    While the findings are promising, researchers caution that more work is needed to confirm the results. Notable limitations include:

    • Lack of data on dementia subtypes like Lewy body and vascular dementia
    • Differences in study design and follow-up durations
    • Unclear long-term cognitive outcomes for different age groups and genders
    • Still, this analysis lays essential groundwork for future research into neurometabolic protection via GLP-1 therapies.

    Originally celebrated as breakthrough treatments for obesity and diabetes, these medications may now be poised to take on an even broader role in preventing neurodegenerative diseases.As Dr. Reddin concluded, “This research marks a significant advancement in how we understand the brain benefits of diabetes medications.”*Disclaimer: This article is based on findings from a study published in JAMA Neurology (July 2024). While the research links GLP-1 drugs like Ozempic and Mounjaro to reduce dementia risk, it is observational and does not prove direct causation. Further studies are needed. Always consult a healthcare provider before making medication decisions.Also Read | 5 coffee routine habits that could be doing more harm than good, say experts


    Continue Reading

  • Anshul Kamboj added as injury cover in India squad ahead of Manchester Test vs England

    Anshul Kamboj added as injury cover in India squad ahead of Manchester Test vs England

    Fast bowler Anshul Kamboj has been added to India’s squad ahead of the fourth Test as a cover for Arshdeep Singh, who suffered a cut on his bowling hand during a training session in Beckenham earlier this week.

    With Arshdeep unlikely to recover in time before the Test in Manchester, which begins on Wednesday, the national selection committee has decided to add the young fast bowler from Haryana as a back-up option.

    Sources in the BCCI confirmed the development to Sportstar and added that the pacer will link up with the squad later on Sunday.

    READ: With series on the line, captain Gill’s real test begins now 

    After a successful domestic season, where he claimed 79 wickets in 24 games for Haryana, Kamboj had a productive stint with India A during its two-match series against England. He claimed five wickets in two games, impressing the selectors with his performance.

    Last season, he claimed a 10-wicket haul in a Ranji Trophy innings, becoming the third cricketer to do so, after Premangshu Chatterjee and Pradeep Sunderram.

    With Arshdeep likely to take another 10 days to recover and Akash Deep still nursing an injury, it would be interesting to see if Kamboj is directly drafted into India’s playing eleven.

    As it rained on Sunday, India’s optional training session remained a closed-door affair. Senior players – including captain Shubman Gill, vice-captain Rishabh Pant, Washington Sundar, K.L. Rahul and Jasprit Bumrah – skipped the session, while the other members spent a couple of hours at the indoor facility. 

    Continue Reading