Author: admin

  • Our Milky Way galaxy may be surrounded by 100 undetected ‘orphan’ galaxies

    Our Milky Way galaxy may be surrounded by 100 undetected ‘orphan’ galaxies

    Our cosmic neighborhood may be far more crowded than previous estimates have suggested. New research hints the Milky Way could have many more small dwarf galaxy “satellites” around it than expected.

    The team, comprised of cosmologists from Durham University, combined supercomputer simulations with mathematical modeling to predict the existence of missing Milky Way “orphan” galaxies. The researchers’ novel technique suggests that as many as 100 extra satellite dwarf galaxies could orbit our large, spiral galaxy.

    Continue Reading

  • BiomEdit raises $18.4m to expand designer probiotics platform

    BiomEdit raises $18.4m to expand designer probiotics platform

    Indiana-based animal microbiome specialist BiomEdit has raised an $18.4 million Series B round and is gearing up to launch its first product, an engineered probiotic (BE-101) to tackle necrotic enteritis, a bacterial affliction driving significant losses in the broiler chicken industry.

    The round—which was led by Anterra Capital with follow-on investment from animal nutrition co Nutreco and new participation from AgriZeroNZ, Elevate Ventures, and Betagro Ventures—will fund BiomEdit through conditional licensure and into the commercial launch of BE-101.

    Spun out of animal health company Elanco in 2022 after partnering with synthetic biology co Ginkgo Bioworks, BiomEdit is working with Diamond Animal Health as its contract development and manufacturing organization to scale production of BE-101. The product, which has entered the final phase of USDA’s conditional licensure process, is expected to launch commercially in late 2026.

    To support the launch, animal health industry execs Kristin Bloink (Elanco) and Andrew Carlson (ADM) have joined BiomEdit’s team as VP of development and CCO, respectively.

    BiomEdit has also secured over $1.7 million in new non-dilutive grants including an USDA grant targeting avian flu with a novel biologic approach, an NIH award for early research into a human therapeutic application based on BiomEdit’s tech, and a Global Methane Hub grant to support its work exploring enteric methane reduction in cattle.

    First-of-its-kind probiotic vectored antibody (pvAb) product

    BE-101, which will assume the brand name Optavant upon full licensure, is a first-of-its-kind probiotic vectored antibody (pvAb) product. It comprises a pair of microbes that BiomEdit has genetically engineered to express antibodies to toxins produced by the bacterium Clostridium perfringens, which causes necrotic enteritis.

    The product is sprayed on the back of birds the day they hatch. “They then peck and preen each other, and ingest the product which is colonizing bacteria, so they don’t need a lot of it,” CEO Aaron Schacht told AgFunderNews in a recent interview.

    “The colony lasts for about two weeks and expresses the biomolecules that target the toxins. We then give a boost in the drinking water to replenish the colony, which gives us coverage for about five weeks of the growth cycle [the typical broiler growth cycle is six weeks].”

    Genomic analysis, metabolomic analysis, and proteomic analysis

    After the spinoff from Elanco, BiomEdit “took advantage of something Elanco had unique access to, the intestinal or fecal content of thousands of animals, and built a library,” said Schacht. “From 2016 to 2021, we sampled and analyzed over 10,000 samples from 7,500 pigs, chickens, fish, cows, and dogs.

    “That was the origin of the sample database that we created, and then we built a platform for culturing these organisms so that we could learn how they grow and then isolate and purify them. And then we could do genomic analysis, metabolomic analysis, and proteomic analysis to see what molecules they made.”

    In parallel, BiomEdit built a strain engineering, gene editing, and synthetic biology capability “with the idea that we would find microbes of interest that could produce feed additives or serve as a delivery vehicle for a targeted molecule if they colonized the gut of the animal,” he explained.

    While BE-101 is its most advanced product, BiomEdit has multiple products in its pipeline, including BE-01, an enzyme that degrades Lipopolysaccharide, which is found in the leftover cell wall remnants from gram-negative bacteria and serves as a potent inflammatory stimulant across all major farm animal species.

    Here, instead of using microbes to deliver the enzyme inside farm animals, BiomEdit uses a microbe to express it at scale, isolate the enzyme and then make the enzyme itself a feed additive. In the process, it had to engineer the host strain to get better at producing and secreting the enzyme, said Schacht. “So there’s an example of where we used synthetic biology to improve a production host.”

    He added: “Separately [as with BE-101, for example] we can use synthetic biology to create products where the microbial host is the product, and it expresses and secretes the molecule in situ [inside the animal].”

    People have been “feeding probiotics to chickens and pigs and cows forever,” said Schacht. “We want to bring real science to [understand] why microbial solutions work, and use synthetic biology to make them even better.”

    Further reading:

    BiomEdit CEO: Next gen designer probiotics will disrupt the animal and human health market

    🎥 Designer probiotics startup ZBiotics has sold 8 million ‘pre-alcohol’ shots, launched new ‘sugar to fiber’ product

    Verb Biotics on next gen biotics: ‘We’re function-first, and we’re not tied into any one organism or flagship strain’

    Continue Reading

  • Apple inks $500m deal for rare earth magnets with US mining firm | Apple

    Apple inks $500m deal for rare earth magnets with US mining firm | Apple

    Apple has signed a $500m deal with a US firm for rare earth magnets, essential for manufacturing electronics, after China curbed exports of the scarce, vital materials.

    The backing from one of the world’s most valuable companies comes after MP Materials, which operates the only US rare earths mine, last week agreed to a multibillion-dollar deal with the US Department of Defense that will see the Pentagon become its largest shareholder. Both deals are aimed at mitigating supply chain risks after China limited the outgoing supply of rare earths earlier this year in response to Donald Trump’s sweeping tariffs.

    The deal, announced on Tuesday, guarantees Apple a steady flow of rare earth magnets free from China – by far the world’s largest producer. For Apple, the cost to support US magnet production pales in comparison to the long-term risk that it could lose access entirely to the critical components, analysts said.

    “We’re in an era where executives are willing to pay a significant premium for a reliable supply chain. They don’t want stoppage,” said Gracelin Baskaran, director of the critical minerals security program at the Center for Strategic and International Studies.

    Rare earths are a group of 17 metals used to make magnets that turn power into motion, including the devices that make cellphones vibrate. They are also used in weapons, electric vehicles and many other electronics.

    China placed export restrictions on rare earths in April in response to Trump’s tariffs. Though the US and China reached a deal in June that has resolved much of the rare earths dispute, broader trade tensions continue to underscore demand for a non-Chinese supply.

    As part of the agreement, Apple will prepay MP $200m for a supply of magnets slated to begin in 2027. The companies did not disclose the length of the deal nor the volumes of magnets to be provided.

    The agreement calls for magnets produced from recycled material, in keeping with Apple’s longstanding goal of ending its reliance on the mining industry. They will be produced at MP’s Fort Worth, Texas, facility using magnets recycled at MP’s Mountain Pass, California, mining complex.

    “Rare earth materials are essential for making advanced technology, and this partnership will help strengthen the supply of these vital materials here in the United States,” Apple’s CEO, Tim Cook, said in a statement.

    Las Vegas-based MP Materials’ stock price has nearly doubled since the government deal was announced. It has had remarkable turnaround since last year, when it contemplated merging with an Australian rival as profits plunged in what its CEO, Jim Litinsky, called a “very frustrating” pricing environment for rare earths.

    Bob O’Donnell, president at market research firm TECHnalysis Research, said Tuesday’s move “makes complete sense” given that Apple requires significant amounts of rare earth magnets for its devices.

    skip past newsletter promotion

    “Plus, by focusing on a US-based supplier, it does help position Apple more positively in Washington,” he said.

    Apple, which said the deal is part of its $500bn four-year investment commitment to the US, has faced threats from Trump over iPhones not made in the US. But many analysts have said making the iPhone in the US is not possible, given labor costs and the existing smartphone supply chain.

    Apple did not disclose which devices in which it will use the magnets. MP said the deal will supply magnets for hundreds of millions of devices, which would constitute a significant share of any of Apple’s product lines.

    MP produces mined and processed rare earths and has said it expects to start commercial magnet production in its Texas facility by the end of this year.

    Continue Reading

  • Israel strikes Damascus military HQ as fighting between Syrian forces and Druze continues – live updates

    Israel strikes Damascus military HQ as fighting between Syrian forces and Druze continues – live updates

    Israel defence minister: ‘Warnings have ended and painful blows to come’published at 14:05 British Summer Time

    Image source, Reuters

    Shortly after Israeli strikes on Damascus began, Israel’s defence minister shared a statement of intent on social media.

    “The warnings in Damascus have ended – now painful blows will come,” Israel Katz writes.

    Katz says the Israeli military will “continue to operate forcefully” in Suweida, the area of southern Syria where Israel has recently intervened in clashes between the minority Druze community and other armed groups.

    He then speaks directly to the Druze community in Israel, saying the Israel Defense Forces will protect the Syrian Druze population.

    “Prime Minister Netanyahu and I, as Minister of Defence, have made a commitment – and we will uphold it,” he adds.

    Katz also shared a video of a live TV news broadcast, showing a building in Damascus being hit by a strike and the on-air newsreader ducking for cover.

    Continue Reading

  • Princess Beatrice’s dreamy curls give Disney vibes

    Princess Beatrice’s dreamy curls give Disney vibes



    Princess Beatrice channels fairytale glamour at 18th birthday.

    Princess Beatrice marked her 18th birthday in 2006 with a celebration straight out of a storybook complete with a grand Victorian ball at Windsor Castle.

    Hosted by her parents, the Duke and Duchess of York, the opulent event invited guests to dress for the occasion in full period attire. 

    The birthday girl stole the spotlight in a show stopping powder blue gown adorned with gold embroidery, a voluminous skirt and bustle, draped sleeves, and a V-shaped neckline.

    The party’s ‘1888 masked ball’ theme held special significance. Beatrice was born exactly a century later, at 8:18 p.m. on August 8, 1988. 

    With over 400 guests donning elaborate costumes, many reportedly spending hundreds of pounds on custom made period pieces.

    Her auburn hair was styled in a dramatic bouffant half updo, with curls far longer than her usual locks, completing her enchanting transformation.

    Princess Eugenie also celebrated the theme in a Hollywood designed gown by The Addams Family costume designer Barbara Matera, paired with elegant white lace gloves.

    Among the attendees were Demi Moore and Ashton Kutcher, Kelly and Jack Osbourne, and Pixie Geldof. 

    However, several senior royals were notably absent, including the late Queen Elizabeth II, King Charles, and Princes William and Harry, who all skipped the extravagant affair.

    Continue Reading

  • Trump tariffs threaten US economy as much as European one, says German finmin – Reuters

    1. Trump tariffs threaten US economy as much as European one, says German finmin  Reuters
    2. EU threatens €72 billion tariffs on US goods amid Stalled Trade Talks  Ptv.com.pk
    3. In Trump’s game of chicken, the EU cannot afford to back down | Nathalie Tocci  The Guardian
    4. Statement by President von der Leyen on EU-U.S. trade  European Commission
    5. EU warns that its trade with the US could be effectively wiped out if Trump follows through on his threat  CNN

    Continue Reading

  • At least 21 people killed in stampede, suffocation at GHF site in Gaza | Israel-Palestine conflict News

    At least 21 people killed in stampede, suffocation at GHF site in Gaza | Israel-Palestine conflict News

    Gaza’s Health Ministry says tear gas was fired on Wednesday at crowds of Palestinians at aid facility in Khan Younis.

    At least 21 Palestinians have been killed in the latest carnage at the GHF aid distribution centre in southern Gaza, with most of the victims reported to have died in a stampede.

    Gaza’s Ministry of Health has disputed the allegation from the controversial United States- and Israel-backed organisation that armed agitators were responsible for the incident on Wednesday morning at the site in Khan Younis.

    In an earlier statement, the GHF had said 19 victims were trampled and another was stabbed “amid a chaotic and dangerous surge”.

    (Al Jazeera)

    Without providing any evidence, it said the stampede had been provoked by “elements within the crowd – armed and affiliated with Hamas”.

    The statement also claimed that GHF staff saw multiple weapons in the crowd and that one of its US contractors was threatened with a gun.

    However, Palestinian witnesses and authorities have vehemently contested the GHF’s version of events.

    One survivor told Al Jazeera, “We were running like everyone else. We got to the gate and realized that it was closed, thousands of people were there. The Americans fired tear gas into the crowd to disperse them which caused a stampede and many people died while being crushed by the crowd”.

    Gaza’s Health Ministry released a statement saying 21 Palestinians had been killed at the GHF site on Wednesday. It noted that 15 of the victims died as a result of a stampede and suffocation after tear gas was fired at crowds of aid seekers.

    “️For the first time, deaths have been recorded due to suffocation and the intense stampede of citizens at aid distribution centres,” the ministry added.

    Speaking from Gaza City on Wednesday, Al Jazeera’s correspondent Hani Mahmoud said a witness had confirmed that tear gas was fired on the crowd, “causing mayhem and chaos”, which led to a stampede.

    Palestinians carry aid supplies
    Palestinians carry aid supplies received from the US-backed GHF in the central Gaza Strip [File: Ramadan Abed/Reuters]

    Meanwhile, a medical source at Nasser Hospital told the AFP news agency that the desperate and starving victims had been trying to receive food, but the main gate to the distribution centre had been closed.

    “The Israeli occupation forces and the centre’s private security personnel opened fire on them, resulting in a large number of deaths and injuries,” they said.

    Since the GHF started operating in the enclave in late May, at least 875 people have been killed trying to get food, according to the United Nations, which said on Tuesday that 674 of these deaths had occurred “in the vicinity of GHF sites”.

    Speaking last week, UN rights office spokeswoman Ravina Shamdasani said most of the casualties had suffered “gunshot injuries”.

    Both the Israeli army and GHF contractors have been accused of carrying out the killings.

    The UN has described the GHF sites as “death traps”, calling them “inherently unsafe” and a breach of humanitarian impartiality standards.

    Amjad Shawa, director of the Palestinian NGOs Network, said on Wednesday that the GHF was guilty of gross mismanagement.

    “People who flock in their thousands (to GHF sites) are hungry and exhausted, and they get squeezed into narrow places, amid shortages of aid and the absence of organisation and discipline by the GHF,” he said.

    The latest deaths near aid distribution centres came as an Israeli attack on a camp of displaced people in al-Mawasi killed nine people.

    In total, at least 81 Palestinians, including 25 people who were seeking aid, have been killed on Wednesday, according to medical sources.

    Continue Reading

  • As Iran Deports a Million Afghans, ‘Where Do We Even Go?’ – The New York Times

    1. As Iran Deports a Million Afghans, ‘Where Do We Even Go?’  The New York Times
    2. The scale of Afghans returning from Iran is overwhelming, says UN official  AP News
    3. The Take: Why are Afghan refugees being sent back to Taliban rule?  Al Jazeera
    4. Empty Promises, Bitter Realities: The Shelter Crisis for Returnees and the Taliban’s Incompetence  8am.media
    5. 8pm News 15 July 2025  Amu TV

    Continue Reading

  • What browser is best for macOS Big Sur?

    What browser is best for macOS Big Sur?

    Chrome and Safari (left) have abandoned or are abandoning support for macOS Big Sur

    You need a browser that gets security updates. If you’re still using macOS macOS Big Sur, soon your only choices will be Firefox and Microsoft Edge.

    Here’s how crucial it is to use a browser that still get updates. Apple recently defended making developers use its WebKit browser engine specifically on the grounds that browsers are such a target for security issues.

    So for safety and privacy as much as for any new features, all users should always use the latest version of whichever browser they choose. But now Google has announced that the current Chrome version 138 “will be the last release to support macOS 11.”

    In a similar note regarding the end of support for Android 8.0 and Android 9.0, Google said that Chrome 139 is tentatively scheduled for release on August 5, 2025.

    Google also stresses how it is essential to run supported versions of Chrome. “On Macs running macOS 11, Chrome will continue to work, showing a warning infobar,” says the support note, “but will not update any further.”

    Apple released macOS 11, called Big Sur, in 2020. It was a major redesign that came alongside the transition from Intel processors to Apple Silicon ones.

    This is the release when Safari gained built-in translation features, and Apple hoped to see developers port Chrome extensions over to it. Safari dropped support for macOS Big Sur, though, in July 2023 with version 16.6.

    Two years later, the current Safari 18.5 requires at least macOS Ventura, which was released in 2022. The developer betas of the forthcoming Safari 26.0 for macOS Tahoe require at least 2023’s macOS Sonoma.

    So the latest versions of Safari are long out of the picture for macOS Big Sur users, and Chrome is ceasing support from August. This leaves only Firefox and Microsoft Edge whose latest versions still support macOS 11.

    On July 16. 2025, the current Firefox 140.0.4 actually supports Macs all the way back to macOS 10.15. That’s macOS Catalina, which was released back in 2019.

    Microsoft Edge also supports macOS Catalina with its current version 128 and its previous 127. However, Microsoft Edge version 129 is expected to be released in September, and after that the browser will require macOS Big Sur.

    Continue Reading

  • Khamenei says Israel war meant to ‘overthrow system’ in Iran

    Khamenei says Israel war meant to ‘overthrow system’ in Iran



    Iran’s Supreme Leader Ayatollah Ali Khamenei speaks in a televised message, after the ceasefire between Iran and Israel, in Tehran, Iran, June 26, 2025. — Reuters 

    Iran’s supreme leader Ayatollah Ali Khamenei on Wednesday said that Israel’s attacks during last month’s 12-day war were intended to weaken the Islamic republic’s system and spark unrest to topple it.

    “The calculation and plan of the aggressors was to weaken the system by targeting certain figures and sensitive centres in Iran,” said Khamenei during a meeting with judiciary officials.

    During the meeting, excerpts of which were published in videos on his website, he said the move was meant to stir “unrest and bring people into the streets to overthrow the system”.

    Israel launched an unprecedented bombing campaign against Iran on June 13, killing top military commanders and nuclear scientists.

    Iranian authorities said more than 1,000 people were killed in Iran.

    During the war, Israeli Prime Minister Benjamin Netanyahu told Fox News that the Israeli strikes “certainly could” bring about a change in the Iranian system.

    “The Iranian regime is very weak,” he said during the interview on June 15.

    Iran responded to the Israeli attacks with drone and missile fire, killing 28 people in Israel, according to Israeli authorities.

    On June 22, Israel’s ally the United States launched unprecedented strikes of its own on Iranian nuclear facilities at Fordo, Isfahan and Natanz.

    Iran hit back with missile strikes on US Al-Udaid airbase in Qatar, which Khamenei described on Wednesday as a “big blow” to the US and warned that “even greater strikes can be dealt to the US and others.”

    A ceasefire between Iran and Israel has been in place since June 24.

    Israel´s attacks took place two days before Iran and the United States were scheduled to meet for a sixth round of nuclear talks which had begun on April 12.

    The talks have not since resumed.

    Tehran has reiterated that it remains open to diplomacy provided that Washington offers guarantees it will not resort to military action against the Islamic republic.

    On Wednesday, Iran’s parliament ruled out negotiations without meeting certain “preconditions”, not giving specifics.

    Khamenei said Iranian diplomats and the military should exercise “care and precision” in the path ahead, without elaborating.

    “Whether we enter the field of diplomacy or the military arena… we will enter from a position of strength.”

    Continue Reading