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Predicts fossil galaxies at z > 15 using non-singular relativity; simulates 180 Gyr; self-refutes if data contradicts its metric evolution.

CURITIBA, PARANá, BRAZIL, July 8, 2025 /EINPresswire.com/ — In a landmark scientific development, ExtractoDAO announces the global release of DUT Quantum Simulator v4.0, the most advanced cosmological simulation platform currently in operation. Powered by a post-singularity reinterpretation of General Relativity, this simulator mathematically forecasts the imminent discovery of gravitationally fossilized galaxies with redshifts z > 15, beyond the explanatory limits of the ΛCDM model.

Using a regularized curvature model and entropy-gradient geodesics, the DUT reproduces structure formation without inflation, singularities, or dark energy. The simulator predicts SRDs (Stellar Remnant Domains) — massive, low-entropy galaxies that formed less than 200 million years after the cosmic turning point — which should become observable by the Roman Space Telescope, ELT (Extremely Large Telescope), and JWST extended missions by 2030. It is the only known simulator equipped with a self-refutation module, capable of rejecting its own predictions if observations contradict its metric evolution.

Far from abandoning Einsteinian physics, this platform formalizes a continuous, horizonless geometry as the natural endpoint of relativistic gravity. This work represents not only a computational tribute to Einstein’s legacy, but also a bold mathematical step into the cosmology of the post-singularity universe.

“This simulator doesn’t discard Einstein — it completes him,” says Dr. Joel Almeida, lead researcher and developer. “By removing singularities and restoring thermodynamic consistency, we fulfill the deepest promise of General Relativity: a universe governed by geometry, not metaphysical explosions.”

Scientific Breakthroughs Enabled by DUT Quantum:
First predictive model for Small Red Dots (SRDs) at z ≈ 20 — low-entropy fossil galaxies formed just 200 Myr after cosmic retraction.

Equation-driven simulation of the universe’s collapse toward a thermodynamic horizon ~166 billion years from now.

Non-singular gravitational potential replacing the Big Bang with structured entropic curvature.

Self-refutation algorithm that automatically invalidates the theory if future data contradict predictions.

Compatibility with JWST, Roman Telescope, and ELT deep-field missions through falsifiable high-z forecasts.

Redefining the Limits of Cosmology

Current ΛCDM simulators — such as IllustrisTNG and EAGLE — saturate at z ≈ 11, bound by assumptions of inflation and cold dark matter. In contrast, DUT Quantum extends simulations far into the future and deep into the cosmic past by utilizing entropy gradients and curvature dynamics.

Observational anomalies like the Hubble tension, CMB Cold Spot, and massive galaxies at z ≈ 16.7 are naturally resolved under the DUT’s gravitational-thermodynamic paradigm — no inflation, no particle dark matter, no cosmological constant.

Confirmations and Forecasts

CEERS-93316 (z ≈ 16.4) and JADES-GS-z13-0 (z ≈ 13.2) align with DUT’s pre-calculated SRD parameters.

Upcoming instruments — Roman Space Telescope (2027) and ESO’s ELT — are expected to confirm the predicted mass–redshift signature of proto-galaxies at z = 17–21.

Scientific Integrity and Open Verification

The simulator is 100% offline, open-source, and utilizes blockchain (via ExtractoDAO Ledger) for hash-traceable reproducibility. Every simulation run is verifiable, and the codebase contains a built-in validation core capable of signaling theoretical collapse when observational inconsistencies emerge.

Official Release and Access

Simulator Repository: https://zenodo.org/records/15838647

Publication: DUT Quantum: The Computational Framework Enabling 180-Billion-Year Cosmological Simulations

Contact: research Joel Almeida ( j.almeida@extractodao.com )

About ExtractoDAO
https://extractodao.com/
ExtractoDAO S.A. is a scientific and financial blockchain company pioneering the integration of smart contracts with cosmological research. By developing decentralized infrastructures for physics, astronomy, and high-precision simulation, it offers open tools for exploring the deepest layers of the universe — and reality itself.

joel almeida
ExtractoDAO S.A
+55 41 98792-2340
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In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing through narrow spaces.

The study suggests that the physical act of moving through tight, confining spaces, like those between tissues, can influence how stem cells develop. This could open new possibilities for engineering materials and therapies by guiding cell behaviour using physical, rather than chemical, signals.

The research was led by Assistant Professor Andrew Holle from the Department of Biomedical Engineering in the College of Design and Engineering at the National University of Singapore (NUS), and the Mechanobiology Institute (MBI) at NUS, and was published on 8 May 2025 in the journal Advanced Science.

Mechanical ‘memory’

Asst Prof Holle leads the Confinement Mechanobiology Lab at MBI. His lab studies how physical constraints – especially the tight spaces cells encounter as they move – affect how cells behave, function, and develop. While most earlier research in this area focused on cancer and immune cells, his team is among the first to explore how these forces affect stem cells, with the aim of applying their findings to future therapies.

The researchers focused on a type of adult stem cell known as a mesenchymal stem cell, or MSC. These cells are found in bone marrow and other tissues and are known for their ability to develop into bone, cartilage, and fat cells. Because of these properties, MSCs are widely used in research on tissue repair and regeneration.

To test how physical forces influence stem cell fate, we developed a specialised microchannel system that mimics the narrow tissue spaces cells navigate in the body.”

Asst Prof. Holle, Confinement Mechanobiology Lab at MBI

They found that when MSCs squeezed through the smallest channels (just three micrometres wide), the pressure caused lasting changes to the cells’ shape and structure. These cells showed increased activity in a gene called RUNX2, which plays a key role in bone formation. Even after exiting the channels, they retained this effect – suggesting they carry a kind of mechanical ‘memory’ of the experience.

“Most people think of stem cell fate as being determined by chemical signals,” Asst Prof Holle said. “What our study shows is that physical confinement alone – squeezing through tight spaces – can also be a powerful trigger for differentiation.”

While traditional methods of directing stem cells rely on chemical cues or growing them on stiff or soft materials, Asst Prof Holle’s team believes confinement-based selection may offer a simpler, cheaper, and potentially safer alternative. “This method requires no chemicals or genetic modification – just a maze for the cells to crawl through,” he said. “In theory, you could scale it up to collect millions of preconditioned cells for therapeutic use.”

Next steps

The researchers say their findings could help improve the design of biomaterials and scaffolds used in bone repair, by creating physical environments that naturally encourage the right kind of cell development. “By tuning the mechanical properties of materials, we might be able to steer stem cells more reliably toward the cell types we want,” Asst Prof Holle said.

The approach could one day be used to speed up recovery from bone fractures or enhance the effectiveness of stem cell therapies. 

“We’d like to test whether preconditioned cells that have gone through this mechanical selection are better at promoting healing when introduced at injury sites,” Asst Prof Holle said. “That’s one of the next steps.”

Beyond bone repair, the research may have broader implications. MSCs are also known to migrate toward tumours, and the research team is interested in whether mechanically preconditioned cells might be better equipped to move through dense tumour tissue – a challenge that has limited the success of many current cell therapies.

The group is also exploring whether the technique could apply to more potent stem cell types, such as induced pluripotent stem cells (iPSCs), which can develop into almost any tissue in the body.

“We suspect that confinement plays a role even in embryonic development,” Asst Prof Holle said. “Cells migrating through crowded environments early in life are exposed to mechanical stress that could shape their fate. We think this idea has potential far beyond just MSCs.”