Author: admin

  • Square Enix celebrates Final Fantasy 9’s 25th anniversary, so where’s the rumoured remake?

    Square Enix celebrates Final Fantasy 9’s 25th anniversary, so where’s the rumoured remake?

    Square Enix has released a special movie to celebrate the 25th anniversary of Final Fantasy 9, but fans are still left wondering what’s going on with the rumoured remake.

    The movie is just a minute long, and is essentially a highlights reel from the game’s FMV sequences, edited over a new recording of the game’s iconic theme song Melodies of Life.

    The video follows a number of other small releases in the run up to the anniversary. Back in March, Square Enix launched a 25th anniversary website for the game that’s slowly been updated with new artwork in celebration of the game’s Japanese release on 7th July 2000 (it was released in the UK a year later in 2001).

    Final Fantasy 9 25th Anniversary Special MovieWatch on YouTube

    New merchandise has also been released, and – perhaps most interestingly – a new prequel picture book has been released from the game’s event designer Kazuhiko Aoki and character designer Toshiyuki Itahana. It details how adorable black mage Vivi got his name – I won’t spoil anything here.

    So where, then, is the rumoured remake?

    The rumour began back in 2021, as part of the infamous Nvidia leak which included a number of unreleased and unannounced Square Enix games. The leak has proven to be accurate so far, following the likes of the Chrono Cross remaster, Final Fantasy 7 Remake, and the recently revealed Final Fantasy Tactics remaster. The Final Fantasy 9 remake is now the only remaining officially unannounced Final Fantasy game from the leak.

    As on the anniversary website, a new vinyl subtitled Timeless Tales is due for release later this week on 9th July – some fans believe this may be the name of the remake itself too.

    Final Fantasy 14’s latest expansion, Dawntrail, also heavily references Final Fantasy 9. This could be coincidence considering the MMORPG regularly references past games, but its director and producer Naoki Yoshida has denied remaking Final Fantasy 9.

    With this 25th anniversary, Square Enix seems to be really pushing Final Fantasy 9. The company announced earlier this year the game had sold 8.9m units worldwide, but this is less than many others in the series, not only including renowned favourite Final Fantasy 7 and the widely released Final Fantasy 15, but also Final Fantasy 8 and 10 – the two games either side of FF9. Where was Final Fantasy 8’s big 25th anniversary?

    Released late in the PS1’s lifecycle, Final Fantasy 9 launched a year after Final Fantasy 8, which proved popular for its realistic graphical style, and a year before Final Fantasy 10 on the more powerful PS2. Though critically well-received, Final Fantasy 9 hasn’t always been the most popular of the series.

    Still, a remake of the game would be great timing for Square Enix. The game’s original PS1 release was seen as a callback to the origins of the series, with its more medieval setting and cartoonish art style. A remake release now – if it stayed true to the original – would parallel this callback at a time Square Enix needs it most.

    The Final Fantasy 7 Remake series has proven divisive in its approach to a remake, despite some welcome modernisation, while Final Fantasy 16 was exemplary for some fans of Square Enix’s decision to move further into action game territory.

    A remake of Final Fantasy 9 would return the company to its turn-based roots and bring newer fans into the series with a classic remake. But at this point, Square Enix is just leaving us waiting.

    If you’re yet to play Final Fantasy 9, a remaster is already available across PC, PS4, Xbox One, Switch, and mobile.

    Continue Reading

  • Windows 11 has finally overtaken Windows 10 as the most used desktop OS

    Windows 11 has finally overtaken Windows 10 as the most used desktop OS

    Microsoft has finally crossed an important milestone for Windows 11, months ahead of Windows 10’s end of support cutoff date. Stat Counter, spotted by Windows Central, now lists Windows 11 as the most used desktop operating system nearly four years after its release, with 52 percent of the market, compared to 44.59 percent for Windows 10.

    Windows 11 became the most popular OS for PC gaming in September, but overall adoption had still been lagging behind Windows 10 until now. Leaked data in October 2023 also revealed Windows 11 was used by more than 400 million devices at the time, a slower adoption pace than Windows 10 — which took just a year to reach 400 million devices compared to Windows 11’s two year period.

    Part of the slow adoption is down to Windows 11’s hardware requirements. While Microsoft offered a free upgrade to Windows 10 users, millions of machines have been left behind due to stricter CPU and security requirements. Microsoft has been trying to convince the owners of these machines to upgrade their hardware in order to get Windows 11, sometimes with a full-screen prompt.

    Windows 10 is due to reach end of support on October 14th, and Microsoft recently revealed it would give away a free year of extra security updates to consumers if they were willing to enable Windows Backup and sync their Documents folder to OneDrive. If you don’t want to do this, you’ll have to pay $30 for a year of updates, or redeem 1,000 Microsoft Reward points.

    Continue Reading

  • How Sony might double down on their anti-consumer practices as PlayStation becomes the only hardware in console space | Esports News

    How Sony might double down on their anti-consumer practices as PlayStation becomes the only hardware in console space | Esports News

    As Xbox pivots to a multiplatform strategy, and Nintendo carves a unique niche, PlayStation might expectedly cement its position as a primary hardware in the console market sooner. The possibility of such an unprecedented market position being enjoyed by Sony has raised some serious concerns—without any fierce competition, could Sony intensify its anti-consumer practices that have priority over profits and not player choices? Historical evidence suggests a troubling path forward.

    Sony might double down on anti-consumer move: What does its playbook suggest?

    With the company’s past as a prologue, there’s a pattern of Sony leveraging market control to restrict user freedom while maximizing revenue. Sony is popularly known for blocking cross-platform for many years. It was only after being under pressure, as Microsoft supported and promoted the feature, that the company gave in.As the data reveals, Sony got exposed demanding royalties from the publishers just to enable the online cross-play. It was a clear tactic for protecting the walled garden revenue.

    Why Sony STILL won’t allow cross-play!

    Further, Sony has even aggressively locked users into the ecosystem. The company enforced a near-total monopoly on PlayStation Store’s digital game sales, prohibiting any third-party retailers from selling the digital codes, unlike its competitors.Popularly known as Sony Tax, this move allows the company to artificially inflate prices. This was clearly evidenced during the UK £5 billion ($6.35 billion approx.) lawsuit. Therein, it was alleged that digital games cost 47% more than the PlayStation’s physical copies.Additionally, Sony was even fined €13.5 million ($14.85 million approx.) previously by the French regulators. It was due to their deliberate attempt to sabotage the third-party PS4 controllers via software updates, while continuing to maintain an opaque licensing program, which stifled the entire competition. When any licensing dispute arises, like 2023’s removal of the purchased Discovery content, users even lose access entirely. It even highlighted Sony’s ownership fragility within the digital domain, serving as one of the most egregious examples of how Sony handheld digital purchases. The entire case was highlighted as Warner Bros. Discovery content got pulled in 2023, from user libraries, without any offered refunds.

    PlayStation DELETING 1200 Titles – NO REFUND 🤯 (All Discovery Content)

    With all being said and considered, the past trends clearly show that Sony is not the one to back down. It will continue to push its anti-consumer policies as and when it gets a chance. Especially with major competition from the console market, it’s highly likely to see that such practices are repeated or, probably, soon, there will be some new way to own a monopoly.

    Why does PlayStation stand alone in shifting the Console landscape?

    Controversial Xbox Strategy: Moving Exclusive Games to PlayStation

    The console landscape has dramatically shifted, and the traditional console war is now dynamically crumbling. Microsoft has already made a fundamental shift in strategy, moving some major exclusives, including “Indiana Jones and the Great Circle” and “Sea of Thieves,” to PlayStation. The company is now heavily promoting Game Pass accessibility across varied devices—mobile and Fire TV. They are signaling to a future that is beyond pure hardware sales. Xbox now competes within an ecosystem, not just the consoles.Meanwhile, Nintendo is thriving on a unique hybrid model and the family-friendly IP. It’s operating in a distinct market segment instead of directly competing for hardcore gamers. Its lower price point is a huge appeal to a broad and casual audience. While some of the franchises here, like Zelda, Mario and Animal Crossing, cater to different demographics than the cinematic and mature exclusives of PlayStation.The focus of Nintendo on affordability and portability, together with its reluctance to engage in a hardware arms race and subscription wars, means it can coexist with PlayStation instead of directly opposing it. Not to mention, as Sony continues to chase high-fidelity graphics and the live-service dominance, Nintendo thrives on nostalgia and accessibility. It ensures Nintendo remains insulated from any cutthroat competition between PlayStation and Xbox.With the changing dynamics, PlayStation now seems to be the only major player that’s solely focused on publishing premium-priced and dedicated console hardware. With Xbox “embracing the multiplatform strategy” and Nintendo “doing its own thing”, Sony now faces diminished pressure from competition, for giving priority to consumer-friendly policies.The company’s dominance within traditional console hardware is now looking to be increasingly uncontested. Sooner, it might allow Sony to enforce some policies, like raising PS Plus subscription price without any addition of meaningful value. It could be riskier in the contested market.

    Sony’s digital dominance and ownership erosion

    Sony’s control over PlayStation Store is the cornerstone of a potential exploitation in the future. Inability to purchase digital games from third-party retailers, including CD Keys like PC platforms or Xbox, creates a captive audience. Such a monopoly would allow Sony to set high prices and resist discounting pressures.The threat extends much beyond pricing. The terms of service of the company explicitly state that users only license the digital content. They do not own it. It was starkly demonstrated as Warner Bros. Discovery content got removed from the user libraries due to expired licensing. With physical media fading, Sony now wields absolute power to revoke access to all purchased media or games, making the libraries of players inherently insecure.

    PlayStation Loyalty faces rising cost, subscription squeeze and proprietary lock-in

    Sony Is Being Sued For Trying To Monopolize Digital Games

    Pricing strategies employed by Sony have grown quite aggressive. The new first-party PlayStation games are now retailing at $70, while the digital versions often cost significantly more than the physical copies. It goes up to 47% more in some of the regions, as per a Dutch lawsuit that sought €1 billion ($1.17 billion approx.) in damages from Sony.The company has even restricted digital game sales to its storefront. It eliminates price competition. On Xbox, players could purchase digital codes from retailers like CDKeys or Amazon, but PlayStation instead locked buyers into Sony’s inflated pricing.Note: The price hikes with the Premium tier taking a jump to $160 annually come with a little justification, especially as Sony has removed perks like PlayStation Plus Collection.Considering all of this, the price of PlayStation Plus now seems to be more strategic and merely inflationary. While it offers few tangible benefits, as compared to all past offerings, Sony now leverages the necessity of service for online play to bring in more revenue. New tiers—Essential, Extra and Premium lack compelling value, quite especially the underwhelming classic game library of Premium. It suggests that Sony’s focus is on profit maximization rather than service enhancement.

    PlayStation is Anti Consumer

    Even hardware lock-ins now look like another tactic. The PlayStation Portal streaming device quite notably lacks standard Bluetooth audio support. It forces users to expensive and proprietary PlayStation Link headsets. It mirrors the costly proprietary memory cards of Vita—artificial banners that have been designed to generate accessory revenue in Sony’s closed ecosystem.

    Sony’s gamble on content control and live services comes with high manipulation tactics

    Sony’s pursuit of live-service games has raised some red flags. While it promised many such titles, only a few materialized, and it was often laden with increased microtransactions. The launch controversy of Gran Turismo 7, where the in-game economy was altered drastically post-release to push MTX purchases after the published reviews, shows Sony’s willingness to manipulate player experience just for profit.

    PlayStation’s Greed Is OUT OF CONTROL… – Gran Turismo 7 MTX, Directors Cuts, Live Service, & MORE!

    Together with a lack of transparency over major first-party single-player releases, much beyond Wolverine and Spider-Man 2, the live-services push shows the future to all, where the players’ engagement would get highly monetized, aggressively. All of it would be possible with Sony’s control over the environment and, quite potentially, at the expense of complete game experiences.

    Roadmap ahead: Sony’s monopoly and power bring consumer risk

    With the diminished competition within the traditional console hardware space, Sony now faces very little incentive to reverse its course. The current trajectory and past both point to Sony doubling down on anti-consumer practices, which can maximize its revenue in walled garden—high subscription cost, strict digital control, aggressive monetization within live-service titles and proprietary hardware dependencies.

    The 10 Worst Things Sony Has Ever Done

    While Sony offers acclaimed exclusives and powerful hardware, the path of PlayStation as a potential sole major hardware player risks prioritizing shareholder value over consumer ownership and choices. There will be a lot of vigilance required in the future from consumers and regulators. It is only then that Sony’s dominance could be prevented from stifling the broader gaming ecosystem.


    Continue Reading

  • All About China Gaming – Niko Partners

    All About China Gaming – Niko Partners

    Niko executives Lisa Hanson and Daniel Ahmad joined Bill Bishop on his Sinocism podcast on Substack Live to dive into the current state of China’s $50 billion games industry and how Chinese companies are making their marks in the global stage. Our 22 years of tracking China’s games industry coupled with Bill’s decades of expertise on China’s politics, economics and policy yielded a lot of food for thought on the pod. Scroll down for the link to view it directly.  

    By the way, Niko News is now available on Substack! If you like your newsletters delivered that way, please subscribe there and recommend us on the platform. We are new to Substack and want to spread the good news, as well as the Niko News! 

    We discussed some hot topics on Sinocism with Bill Bishop, concerning China’s games industry and international growth of Chinese game companies. Here are a few points we talked about: 

    • The international expansion of the two giants in the Chinese game scene: Tencent and NetEase, as well as their domestic success and evergreen titles.  
    • Non-licensed games can find success through Steam international as Chinese gamers can access both the Chinese and international version of Steam.  
    • More game developers or publishers turn to generative AI (genAI) for game development to increase efficiency and lower cost. Almost half of Chinese gamers are both aware and interested in the leveraging of gen AI in video games. 

    Watch the full episode here (42 minutes).  

    Check out our reports and services to help you staying up to date on the China video game market: 

    NikoIQ: Get the latest updates on game approvals, the top internet café games, esports tournaments and all the latest news and analysis on the China games market. 

    China Games & Streaming Tracker: Track games, streamers, fans, tips, and more across China’s leading game live streaming platforms. 

    China Games Market Report Series: Get access to our three-part report series that includes our market model and five-year forecast, gamer survey insights, and market analysis. 

    Related Articles


    Continue Reading

  • Max Stock Limited releases an immediate report on holdings of interested parties and senior officers as of June 30, 2025

    Regulations 33(c)-(d) of the Securities Regulations (Periodic and Immediate Reports), 1970

    CAESAREA, Israel, July 7, 2025 /PRNewswire/ — Max Stock Limited (TASE: MAXO) (the “Company”) today announced holdings of interested parties and senior officers as of June 30, 2025:

    Corporation’s interested parties (including the CEO and directors, and including any other employee holding 5% or more of the corporation’s issued share capital or voting rights):

    Holder no.

    Holder’s Name

    Name, class and series of security

    Updated no. of securities

    % holdings

    % equity      % voting

    % holdings (on a fully diluted basis)

    % equity % voting

    1

    Moose Holdco Ltd.

    Max Stock Ordinary Share

    31,558,386

    22.61           22.61

    22.43            22.43

    2

    Ori Max

    Max Stock Ordinary Share

    24,981,492

    17.90           17.90

    17.76            17.76

    3

    Y.D. More Investments Ltd. (Mutual Funds)

    Max Stock Ordinary Share

    2,362,904

    1.69             1.69

    1.68              1.68

    4

    More Provident Funds and Pension Ltd. (Provident Funds)

    Max Stock Ordinary Share

    12,066,976

    8.65             8.65

    8.58              8.58

    5

    Max Stock Ltd.

    Max Stock Ordinary Share

    3,658,971

    0.00             0.00

    0.00              0.00

    6

    Migdal Insurance and Financial Holdings Ltd – Profit sharing life insurance policies

    Max Stock Ordinary Share

    9,600,229

    6.88             6.88

    6.82              6.82

    7

    Migdal Insurance and Financial Holdings Ltd. – Mutual funds management companies

    Max Stock Ordinary Share

    1,850,609

    1.33             1.33

    1.32              1.32

    8

    G. Gissin Advocates

    Max Stock Ordinary Share

    44,087

    0.03             0.03

    0.03              0.03

    9

    Ibex Israel Fund LLP

    Max Stock Ordinary Share

    7,315,547

    5.24             5.24

    5.20              5.20

    % holdings

    % equity    % voting

    % holdings (on a fully diluted basis)

    % equity   % voting

    64.33          64.33

    63.82                63.82

    B. Corporation’s senior officers (excluding the CEO and directors, and excluding any other employee holding 5% or more of the corporation’s issued share capital or voting rights):

    Presented below is a summary table of the holdings of the corporation’s senior officers:

    Holder no.

    Holder’s Name

    Name, class and series of security

    Updated no. of securities

    % holdings

    % equity      % voting

    % holdings (on a fully diluted basis)

    % equity % voting

    10

    Shlomo Cohen

    Max Stock Op2020 share options

    102,695

    0                      0

    0.07      0.07

    11

    Nir Dagan

    Max Stock Op2020 share options

    48,987

    0                      0

    0.03      0.03

    12

    Shahar Kanizo

    Max Stock Op2020 share options

    23,619

    0                      0

    0.02      0.02

    13

    Ofir Edri

    Max Stock Op2020 share options

    94,326

    0                      0

    0.07      0.07

    % holdings

    % equity    % voting

    % holdings (on a fully diluted basis)

    % equity   % voting

    0                      0

    0.19          0.19

    The summary table below includes an overview of interested party holdings which were subject to a change in the reporting period:

    Name

    Balance in previous report

    (31-Mar-2025)

    Change (+/-)

    Maximal holding in period (%)

    Minimal holding in period (%)

    Comments

    Moose Holdco Ltd.

    39,350,594

    -7,792,208



    (*) Moose Holdco and the Company’s other controlling shareholder and CEO, Mr. Ori Max, are party to a shareholder agreement regulating their relationship.

    The Company has been informed that Moose Holdco is wholly (100%) owned (indirectly) by AMI Opportunities, a foreign private investment fund (incorporated in Guernsey). AMI Opportunities is wholly-controlled (indirectly) by AMI Foundation. To the Company’s best knowledge, AMI Foundation is advised by Apax Partners Israel Ltd.

    Y.D. More Investments Ltd.

    1,853,406

    +509,498

    1.69 %

    1.29 %

    (*) Y.D. More Investments Ltd. (“More Investments”) holds more than 5% of Max Stock’s share capital through the mutual funds and provident funds managed by More Investments. More Investments is a public company jointly owned through a holding structure by Messrs. Eli Levi, Yosef Levi, Binyamin, Yosef, Michael and Dotan Meirov.

    More Provident Funds & Pension Ltd.

    12,885,350

    -818,374

    9.00 %

    8.64 %

    See above.

    Migdal Holdings Insurance & Finance Ltd – Profit sharing life insurance policies

    7,327,501

    +2,272,728

    6.88 %

    5.25 %

    (*) Migdal Insurance & Financial Holdings Ltd. (“Migdal”) holds more than 5% of Max Stock’s share capital through the mutual funds and provident funds managed by the Migdal corporate group. Migdal is a public company which is ultimately controlled by Mr. Shlomo Eliyahu (48.59%).

    Migdal Holdings Insurance & Finance Ltd. – Mutual funds management companies

    1,103,199

    +747,410

    1.37 %

    0.72 %

    See above.

    Shlomo Cohen

    102,775

    -80



    Exercise of employee options.

    (*) As notified to the Company by the interested party or to the best of the Company’s knowledge.

    This is an English translation of segments of a Hebrew immediate report that was published on July 7, 2025 (Ref. No. 2025-01-049563) (hereinafter: the “Hebrew Version“). This English version is only for convenience purposes. This is not an official translation and has no binding force. Whilst reasonable care and skill have been exercised in the preparation hereof, no translation can ever perfectly reflect the Hebrew Version. In the event of any discrepancy between the Hebrew Version and this translation, the Hebrew Version shall prevail.

    About Max Stock
    Max Stock is Israel’s leading extreme value retailer, currently present in 64 locations throughout Israel. We offer a broad assortment of quality products for customers’ everyday needs at affordable prices, helping customers “Dream Big, Pay Small”. For more information, please visit https://ir.maxstock.co.il,

    Company Contacts:
    Talia Sessler,
    Chief Corporate Development and IR Officer
    [email protected]

    SOURCE Max Stock Limited

    Continue Reading

  • Hertz adopts AI for fleet and workforce management

    Hertz adopts AI for fleet and workforce management

    Hertz got its start renting out a dozen Model T Fords more than 100 years ago. Today, Hertz operates in 160 countries and has more than 20,000 employees and 500,000 vehicles in its fleet. To streamline an operation with so many moving parts, the company has deployed Hertz Connected Fleet OS, an AI-enabled operating system for fleet management.

    “This is all around our purpose for our customers, which is making sure we have the right car, at the right place, at the right time,” said EVP and CIO Tim Langley-Hawthorne at Palantir’s AIPC last month, before stepping down from the role soon after. “It orchestrates customers, vehicles, and workforce. Those are the three critical components for businesses like ours on the ground.”

    Hertz has leveraged Palantir Foundry and Palantir Artificial Intelligence Platform (AIP) to create a set of AI-powered applications to help it increase efficiencies in vehicle turnaround, reduce maintenance expenses, predictively allocate its workforce across field locations, and match the best car to customers.

    Continue Reading

  • Stay buckled up, the market ride is going to get wilder still, says this strategist – MarketWatch

    1. Stay buckled up, the market ride is going to get wilder still, says this strategist  MarketWatch
    2. S&P 500 just saw its first ‘golden cross’ in more than 2 years. Here’s what comes next.  MarketWatch
    3. Watch out: The threats that could derail the big rally  TheStreet
    4. BlackRock’s Rick Rieder says there is a ‘generational opportunity’ for income right now  CNBC
    5. Can the bull market in US stocks continue? Analyst: Looking at history, it can continue to rise, but the “threshold” is higher.  富途牛牛

    Continue Reading

  • Android 16 is causing lock-screen issues on some Pixel phones – here’s what we know

    Android 16 is causing lock-screen issues on some Pixel phones – here’s what we know


    • Some Pixel owners are reporting Android 16 lock-screen issues
    • They say the screen can be laggy and unresponsive
    • So far, Google hasn’t issued any official advice about the issue

    The official Android 16 rollout got underway last month, with the best Pixel phones first in line for the update – but it appears that the software is causing lock-screen issues for a significant number of Pixel owners.

    A variety of problems have been reported, as per 9to5Google. These include the lock screen not waking up when tapped, and not responding to a press of the power button, as well as fingerprint ID issues and extreme variations in brightness.

    Continue Reading

  • If You’re a Prime Member, the Fire TV Stick Range Is 50% Off on Amazon

    If You’re a Prime Member, the Fire TV Stick Range Is 50% Off on Amazon

    For Prime Day, Amazon is (once again) rolling out some of the best deals of the year on its own products. Whether you’re interested in a Kindle, a Ring or Blink security system, or the ever-popular Fire TV Sticks, these limited-time offers are the best you can get.

    This year, the discounts on Fire TV Sticks go even deeper than last year with the Amazon HDMI streaming dongles hitting their lowest prices ever. It’s important to note that these are Prime Deals, so you’ll need a Prime membership to access the savings. If you’re not a member yet, you can also join the free 30-day trial and still enjoy these record-low prices.

    The Fire TV Stick 4K is now discounted to just $24 from its regular $49. The Fire TV Stick 4K Max with even more high-end features is reduced to $34 from $59. If you’re wanting the most affordable option, the Fire TV Stick HD is just $17, reduced from its normal $34. Prices this low, it’s a good idea to grab a few extra devices for different rooms or even as gifts.

    See Fire TV Stick 4K at Amazon

    See Fire TV Stick HD at Amazon

    See Fire TV Stick 4K Max at Amazon

    AI-Powered Search

    The star of the show is the Fire TV Stick 4K and it delivers a powerful streaming experience in a compact size. It supports 4K Ultra HD, Dolby Vision, HDR, and HDR10+, so you’ll enjoy sharp details on compatible TVs. It also boasts Wi-Fi 6 for a fast and stable connection and smooth streaming even if you have multiple devices connected to your home network. The newest model also features AI-powered Fire TV Search. With access to over 1.5 million movies and TV episodes, plus free and live TV options, you’ll never run out of things to watch.

    Setting up the Fire TV Stick 4K is simple: Plug it into your TV’s HDMI port, connect to Wi-Fi, and you’re ready to stream. The Alexa Voice Remote that’s included lets you search for content and even control compatible smart home devices using only your voice. You can use the remote to turn up the volume, mute the TV, or launch apps without needing to touch a button.

    Even the Fire TV Stick HD, Amazon’s entry-level model, offers a strong streaming experience with HD resolution, Alexa Voice Remote, and smart home controls. The Fire TV Stick 4K Max offers a faster streaming experience and improved connectivity compared to the Fire TV Stick 4K, thanks to its more powerful processor, expanded storage, and support for Wi-Fi 6E.

    If you’re looking to modernize your home entertainment system, these Fire TV Stick deals for Prime Day represent some of the best value you’ll find all year. Make sure you don’t miss this opportunity before it runs out of stock.

    See Fire TV Stick 4K at Amazon

    Continue Reading

  • Stressful Life Events Linked to Alzheimer’s Risk

    Stressful Life Events Linked to Alzheimer’s Risk


    Register for free to listen to this article

    Thank you. Listen to this article using the player above.


    Want to listen to this article for FREE?


    Complete the form below to unlock access to ALL audio articles.

    Stressful life events can negatively impact brain health. Specifically, grief over the loss of a partner has been linked to alterations in biological processes associated with Alzheimer’s disease, while unemployment and financial loss have been associated with structural differences in the brain. These are the main conclusions of a study conducted by the Barcelona Institute for Global Health (ISGlobal), a centre promoted by ”la Caixa” Foundation, and the Barcelonaβeta Brain Research Centre (BBRC), a research centre of the Pasqual Maragall Foundation. The results, which highlight differences in the brain’s response to stressful events according to gender and educational level, have been published in the journal Neurology.

    Led by Eider Arenaza-Urquijo, an ISGlobal researcher, the study involved 1,200 people from the ALFA (ALzheimer’s and FAmilies) cohort at the BBRC, which is promoted by ”la Caixa” Foundation. The participants were individuals without cognitive impairment, most of whom had a family history of Alzheimer’s disease. “Using magnetic resonance imaging, we studied the differences in grey matter volume in the brain and analysed Alzheimer’s disease biomarkers in the cerebrospinal fluid, such as beta-amyloid protein,” explains Eleni Palpatzis, a pre-doctoral researcher at ISGlobal and first author of the study.

    The impact of grief and economics on the brain

    In Alzheimer’s disease, changes in the brain—such as alterations in the levels of certain proteins—can occur years before the first symptoms appear. For example, a lower ratio of amyloid beta 42/40 is observed; this ratio compares the concentrations of two forms of the protein. Since amyloid beta 42 is more likely to aggregate in the brain, a decrease in this ratio in the cerebrospinal fluid usually reflects greater amyloid beta deposition in brain tissue, making it an important early indicator of Alzheimer’s disease. Higher levels of phosphorylated tau, which causes neuronal damage, and neurogranin, which increases when connections between neurons are lost, are also found.

    The death of a partner was associated with changes in these biomarkers: a lower amyloid beta 42/40 ratio (an effect that was more pronounced in men), and higher levels of phosphorylated tau and neurogranin (effects that were more pronounced in women). All of these effects were more pronounced in people with lower levels of education.

    Conversely, unemployment and economic losses were associated with a lower grey matter volume in key brain regions responsible for emotional and cognitive regulation. Gender differences were also evident in these effects; unemployment affected men’s brains more, while economic losses had a greater structural impact on women’s brains.

    The role of inequality in Alzheimer’s

    A previous study by the same group already showed that exposure to stressful life events in middle age can increase vulnerability to Alzheimer’s disease. However, the prevalence and impact of stressful life events varies according to certain social determinants, such as gender and education; women and people with lower levels of education experience more stressful life events, and it is also in these groups that the prevalence of Alzheimer’s is most prevalent. The research showed that different stressful situations affect men and women differently.

    “Men seem to be more negatively affected by the loss of a partner (which affects amyloid-related proteins) and unemployment (which reduces grey matter). This may be because men tend to have fewer close relationships, making the loss of a partner more isolating, so the loss of a partner is more isolating for them, and because unemployment carries a greater social stigma for men,” explains Eider Arenaza-Urquijo, ISGlobal researcher and senior author of the study.

    “On the other hand, women seem more vulnerable to financial difficulties, which affect grey matter volume. This could be related to the fact that women have historically had less financial security, and that they tend to report higher levels of economic concern, which negatively impacts their overall mental well-being,” adds the researcher.

    Reference: Palpatzis E, Akinci M, Garcia-Prat M, et al. Grief and economic stressors by sex, gender, and education: associations with Alzheimer disease–related outcomes. Neurology. 2025;104(8). doi: 10.1212/wnl.0000000000213377

    This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source. Our press release publishing policy can be accessed here.

    Continue Reading