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  • Measles cases in the US reach 33-year high

    Measles cases in the US reach 33-year high

    The number of reported measles cases in the US has reached a 33-year high, with nearly 1,300 confirmed infections across the country as of Friday.

    The data, released by John Hopkins University, marks a new milestone in an ongoing outbreak of the highly contagious, vaccine-preventable disease that was once thought to be eliminated in the US.

    Measles cases have been reported in 38 states and the District of Columbia this year. At least three people have died from the illness, and 155 others were in hospital.

    A vast majority of the measles cases – 92% – were in people who were either unvaccinated or whose vaccination status was unknown, according to the Centres for Disease Control (CDC).

    The worst hit state is Texas, CDC data shows, where more than 700 cases have been reported. Other states with dozens of cases include Kansas and New Mexico.

    Health officials say that measles spread is occurring mostly in neighbourhoods where vaccination rates are lower, such as Mennonite communities in Texas that opt out of modern medicine.

    The outbreak comes as anti-vaccine sentiment in the US and elsewhere has grown in recent years.

    Health Secretary Robert F Kennedy Jr had previously spread misinformation about childhood vaccinations and had minimised the outbreak. He later endorsed the measles, mumps and rubella vaccine as illness spread, saying in a post on X that it is “the most effective way to prevent the spread of measles”.

    Measles cases in the US were at their highest in recent memory in 1990, with nearly 28,000 reported infections, according to CDC data.

    The illness was later declared eliminated around the year 2000, when cases sharply declined to less than 90 thanks to high vaccination rates and rapid outbreak response.

    Cases started ticking up slightly in 2014 and again in 2019, when 1,274 confirmed infections were reported. But cases in 2025 have just surpassed that figure, with 1,277 infections now reported across the US.

    Public health experts have said that the US will lose measles elimination status if there is continued spread of measles at the current rate for more than 12 months.

    As a result of the current outbreak, more people are now getting the measles vaccine in the US. Between 1 January and 16 March, Texas gave at least 173, 000 measles doses compared to 158,000 in the same time period last year, state health department data shows.

    The MMR vaccine is the most effective way to fight off the dangerous virus, which can lead to pneumonia, brain swelling and death. The jabs are 97% effective and also immunise against mumps and rubella.

    Large measles outbreaks have been reported recently in other countries, including the UK. Last year marked the highest number of confirmed measles cases reported in England since 2012 at nearly 3,000.

    Since January of this year, there had been 529 cases reported in England.

    Canada is also experiencing a measles outbreak, with more than 3,000 cases reported in 2025 so far. The bulk of the cases are in the provinces of Ontario and Alberta.

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  • Woman who had skin cancer warns of sunbed danger

    Woman who had skin cancer warns of sunbed danger

    Stuart Maisner

    BBC News, South East

    Levi-Mariah Verrall Close up image of Levi-Mariah VerrallLevi-Mariah Verrall

    Levi-Mariah Verrall had been using sunbeds since she was 16

    A woman from Kent has warned of the dangers of excessive sunbathing and sunbed use after she had surgery on her face for skin cancer.

    Levi-Mariah Verrall, 33, from Rochester, started using sunbeds when she was 16.

    She described herself as “pale-skinned and freckly”, but said she would “lay in the sun whenever I could”.

    Ms Verrall said: “We’re all told about the dangers of sunbeds now, and having too much sun, but you never think it’s going to happen to you.”

    She said she used oil for sunbathing, adding: “I didn’t use high-factor sunscreen or cover up when I was out.”

    In 2022, her partner noticed a white patch on her face.

    She said: “I thought it was just pigmentation, because it didn’t look like a mole or what I took to be the usual signs of skin cancer.

    “Even the GP thought it was pigmentation.

    “But I wasn’t happy because it just didn’t look right so I pushed for some tests.”

    A biopsy revealed she had basal cell carcinoma, the most common form of skin cancer which develops from cells found in the deepest part of the outer layer of the skin.

    For most people, this type of cancer does not spread.

    It can be removed by surgery and no further treatment is required.

    However, Ms Verrall’s carcinoma needed a deep and lengthy incision to remove all traces of it.

    Levi-Mariah Verrall Close up of the right side of Levi-Mariah Verrall's face showing skars under the eye after skin cancer surgeryLevi-Mariah Verrall

    Ms Verrall was operated on when she was 30

    Around 3,100 people are diagnosed with skin cancer every year in the south-east of England, according to Cancer Research UK.

    Ms Verrall, who runs an industrial door company, said she is now passionate about urging people to look after their skin.

    “What I went through was traumatising and I don’t want other people to experience that,” she said.

    Beth Vincent, Cancer Research UK health information manager, said: “Getting sunburnt just once every two years can triple the risk of developing skin cancer, compared to never being burnt.

    “Even on a cloudy day, the sun can be strong enough to burn between mid-March and mid-October.”

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  • ‘He absolutely deserves this moment’ – The F1 paddock reacts to Nico Hulkenberg’s maiden podium

    ‘He absolutely deserves this moment’ – The F1 paddock reacts to Nico Hulkenberg’s maiden podium

    Nico Hulkenberg finished third at Silverstone for Kick Sauber to score his maiden F1 podium at the 239th time of asking. For a driver one month short of his 38th birthday, it was an incredible result – not least because it was achieved from 19th on the grid.

    The German made his F1 debut all the way back in 2010, and his career in the sport looked to be over when he was left without a seat at the conclusion of the 2019 season.

    But after two years on the sidelines bar a handful of ‘super sub’ appearances, Hulkenberg was handed a lifeline to return to F1 in 2022 with Haas – and since then has put in a string of strong performances.

    You only have to look at the last handful of races, since Kick Sauber introduced an upgrade package, to see the kind of performances the German is delivering. P16 on the grid in Spain became fifth at the flag, P13 on the grid in Canada resulted in an eighth-place finish and then Hulkenberg started 20th last weekend in Austria, climbing up to finish ninth.

    All of those results were dwarfed by his drive at Silverstone, with his colleagues old and new swift to offer their congratulations.

    Team mate Gabriel Bortoleto was on hand to hug the German as he parked up at the end of the race, saying: “Congratulations to Nico! Seeing him fight for the podium and achieve this result after so many years in Formula 1 means a lot. He is the best teammate I have ever worked with – both as a driver and as a person – and he absolutely deserves this moment: I am genuinely happy for him.”

    Max Verstappen was also swift to go over to Hulkenberg in parc ferme and shake his hand, before saying afterwards that “the race wasn’t that enjoyable for me but it was nice to see Nico get his first podium and I’m sure he will be celebrating tonight.”

    Oscar Piastri shared the podium with Hulkenberg, and while the Australian was another left disappointed with their own result, seeing the Sauber driver’s celebrations at least tempered Piastri’s own frustrations.

    “Well done to Nico – I think that’s the highlight of the day,” Piastri said in his post-race interview.

    ‘He’s always been a top-five driver’

    Williams’ Carlos Sainz – a former team mate of Hulkenberg at Renault in 2018 – was also hugely complimentary towards the German after he secured his long-awaited podium. “Congrats – he must have done a very solid race to be up there in P3,” the Spaniard told media.

    “Honestly, for me, the fact that people kept cursing him, the fact that he didn’t have any podiums, for me it was completely irrelevant. For me, he’s always been a top-five driver in the grid every time he’s been in F1 – his level of talent and race execution is incredible.”

    Williams Team Principal James Vowles also added: “Congratulations to Sauber and to Nico – an extraordinary result today and well-earned in these difficult conditions.”

    Ferrari driver Lewis Hamilton was the man chasing Hulkenberg in the closing stages of the race, unable to get close enough to steal the podium position and maintain his streak of podium finishes at Silverstone.

    While his own streak came to an end, the Briton praised what the Sauber driver had achieved. “Third place felt within reach at times but credit to Nico on his first podium, he drove a strong race,” Hamilton concluded

    “Congratulations to Nico for his podium, it’s a great achievement for him and his team,” added Hamilton’s team mate Charles Leclerc, before team boss Fred Vasseur gave his own opinion: “Finally, congratulations to Nico on his first podium. Given his undoubted talent, he deserves it.”

    The last word had to go to Piastri though, who turned to Hulkenberg in the post-race press conference and asked the German how he felt about his first ever F1 trophy being made of… Lego.

    “I love Lego!” laughed the German. “It’s good. My daughter can play with it too.

    “You’ve always got to see the bright side. But, you know, a bit of silver or gold would have been nice too, but I won’t complain.”

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  • Cardiologist shares new sugar alternative that ‘doesn’t spike insulin levels and reduces body fat’

    Cardiologist shares new sugar alternative that ‘doesn’t spike insulin levels and reduces body fat’

    Until now, the only healthy alternatives to sugar have been known as stevia, truvia, monk fruit extract, coconut sugar, date sugar and more. All of these might be healthier for consumption than sugar but do have similar harmful effects on the body in lesser quantities.Now, an expert has shared a unique alternative to sugar that not only doesn’t spike blood sugar and insulin levels but also reduces fat. Dr Alok Chopra, cardiologist and functional medicine expert defined the alternative as allulose, which is 70% as sweet as sugar.“Allulose is a rare sugar alternative that doesn’t spike blood sugar or insulin levels, making it a promising option for those managing diabetes or insulin resistance,” shared the doctor on Instagram. Additionally, he added that 70% of allulose is absorbed in the blood and passes out in the urine.

    What are the benefits of allulose?

    The doctor even mentioned the benefits of consuming allulose:Low calories: With just 0.2-0.4 calories per gram, it consists of only 1/10th of the calories of sugar.Vital for organs: It is safe for vital organs such as the liver, kidneys and fat tissues and also reduces inflammation and oxidative stress.Healthy for blood-sugar: With its low glycemic index, allulose improves insulin sensitivity and reduces post-meal glucose spikes.Increases energy: Allulose not only boosts mitochondrial function but also improves endurance and protects the body against diabetic nephropathy.Improves metabolism and reduces fat: Allulose also helps in fat burning, reduces body fat and enhances feelings of satiation.

    What are the natural sources of Allulose?

    What are the natural sources of Allulose?

    Image credits: X

    Naturally, allulose is present in small amounts in wheat figs, raisins, molasses, maple syrup, jackfruit, kiwi, caramel, juices and coffee. In terms of commercial production, they are made enzymatically by converting fructose, making it affordable and accessible.

    How is Allulose better than other alternatives?

    Well, according to the cardiologist, all other sugar alternatives are nothing when compared to allulose. He added how stevia and truvia are often mixed with artificial sweeteners and their long-term use can increase craving and weight. Other sugars such as coconut and date are natural but have varying glycemic impacts.According to a study published in the National Library of Medicine, a 5g-10g intake of allulose per meal is effective enough to lower postprandial blood glucose levels.Disclaimer: This article is for information purposes only. Consult a certified physician before pursuing any new changes in diet.


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  • FDA approves first-of-a-kind oral therapy for rare disease

    FDA approves first-of-a-kind oral therapy for rare disease

    The US drug agency’s authorisation provides hereditary angioedema (HAE) patients with the first new on-demand treatment in over ten years.

    FDA hereditary angioedema

    The US Food and Drug Administration (FDA) has approved the first oral on-demand therapy for acute attacks of hereditary angioedema (HAE) in individuals aged 12 years and older.

    This rare genetic disease leads to tissue swelling attacks in the body that can be life-threatening. It is caused by a deficiency or dysfunction in the C1 esterase inhibitor (C1INH) protein and subsequent uncontrolled activation of the kallikrein-kinin system, KalVista Pharmaceuticals shared.

    The company’s novel plasma kallikrein inhibitor Ekterly® (sebetralstat) “enables people to treat attacks the moment symptoms begin, wherever they are,” commented Ben Palleiko, CEO of KalVista Pharmaceuticals.

    Significance of the FDA’s hereditary angioedema treatment approval

    “This is an important moment for patients, giving people living with HAE a treatment option that could provide greater independence and control over managing their condition,” explained Dr Marc Riedl, Professor of Medicine and Clinical Director, U.S. Hereditary Angioedema Association Center at the University of California, San Diego, and an investigator for the KONFIDENT Phase III trial.

    “Until now, on-demand treatment relied on injectable subcutaneous or intravenous administration, often resulting in delayed intervention. Having an oral option empowers patients to treat attacks early, which aligns with treatment guidelines and advances our goal as physicians to reduce the overall burden of disease.”

    “Until now, on-demand treatment for [hereditary angioedema] relied on injectable subcutaneous or intravenous administration, often resulting in delayed intervention”

    The Phase III KONFIDENT clinical trial, part of the largest clinical trial programme conducted in HAE, found that Ekterly “achieved significantly faster symptom relief, reduction in attack severity and attack resolution than placebo, and was well-tolerated with a safety profile similar to placebo”, KalVista Pharmaceuticals shared.

    These results for the small molecule therapy are further supported by data from the extension KONFIDENT-S clinical trial. As of September 2024, attacks could be treated with Ekterly in a median of 10 minutes following onset.

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  • Escalating to Biologic Therapy in a 5-Year-Old With Severe Atopic Dermatitis

    Escalating to Biologic Therapy in a 5-Year-Old With Severe Atopic Dermatitis

    Video content above is prompted by the following:

    This case study illustrates the critical decision-making process when managing severe pediatric atopic dermatitis that significantly affects a child’s quality of life and development. The 5-year-old patient presented with severe disease covering greater than 10% body surface area, experiencing 4 to 5 nighttime awakenings and demonstrating academic performance issues requiring parental intervention with school officials. The presence of comorbid conditions, including food allergies and mild asthma, further complicated the clinical picture, highlighting the interconnected nature of atopic diseases and the need for comprehensive treatment approaches.

    The case demonstrates clear indicators for systemic therapy escalation, including disease severity, significant sleep disruption, and functional impairment affecting school performance. The patient’s additional allergic conditions, particularly asthma, influenced treatment selection toward dupilumab, which offers proven efficacy for both atopic dermatitis and asthma management. Findings from clinical studies demonstrate dupilumab’s effectiveness beginning as early as 2 to 4 weeks after initiation, with substantial improvements typically observed by 16 weeks and sustained benefits over 52 weeks, providing families with realistic expectations for treatment response.

    Shared decision-making in pediatric atopic dermatitis requires careful balance between parental concerns and age-appropriate patient involvement. Health care providers must communicate in language accessible to both children and parents, ensuring all parties understand treatment options, expected outcomes, and safety considerations. The excellent safety profile of dupilumab in pediatric populations, with approval for patients as young as 6 months, provides reassurance for families considering biologic therapy. Successful treatment adherence strategies include addressing injection anxiety through techniques such as vibration tools, ice application, and positive reinforcement systems.

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  • Addressing Comorbidities and Skin of Color Considerations in a 55-Year-Old With Newly Diagnosed Atopic Dermatitis

    Addressing Comorbidities and Skin of Color Considerations in a 55-Year-Old With Newly Diagnosed Atopic Dermatitis

    Video content above is prompted by the following:

    Adult-onset atopic dermatitis presents unique diagnostic challenges, particularly in patients with darker skin tones where traditional clinical presentations may differ significantly from textbook descriptions. This 55-year-old African American patient’s case highlights the importance of maintaining a broad differential diagnosis when evaluating new-onset eczematous conditions in adults, including considerations for contact dermatitis, cutaneous T-cell lymphoma, and drug-induced rashes. The patient’s history of occasional childhood rashes suggests possible long-standing disease that remained undiagnosed, emphasizing the need for improved disease recognition and earlier intervention.

    Delayed diagnosis and treatment of atopic dermatitis disproportionately affect patients with skin of color, often resulting in more severe disease presentation and greater functional impairment by the time patients seek dermatologic care. In darker skin tones, the characteristic erythema of atopic dermatitis may present as hyperpigmentation or violaceous discoloration rather than bright red inflammation. Additionally, patients with skin of color may develop different disease variants, including more nodular, papular, or follicular presentations, which can complicate accurate diagnosis and appropriate treatment selection.

    Treatment planning for this patient required careful consideration of multiple comorbidities, including type 2 diabetes, chronic kidney disease, and hypertension. Although these conditions do not represent absolute contraindications to any specific therapy, they influence treatment selection toward options with favorable safety profiles. The patient’s concerns about postinflammatory hyperpigmentation necessitated specific counseling about realistic expectations for improvement, as hyperpigmentation resolution can take months to years. Education about the relationship between inflammatory control and hyperpigmentation prevention becomes crucial for treatment adherence and patient satisfaction.

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  • Virtual mindfulness meditation apps improve cognitive focus in adults

    Virtual mindfulness meditation apps improve cognitive focus in adults

    Studies suggest mindfulness meditation can improve cognition, but few researchers have examined whether virtual mindfulness meditation apps are effective. In a new eNeuro paper, Andy Kim et al., from the University of Southern California, assessed attention control in adults following about a month of mindfulness meditation guided by a mobile app. 

    In participants of all ages, mindfulness improved attention control as measured by reliable eye movement tasks established to assess how quickly people orient their attention. A control group that listened to an audio book did not have this cognitive improvement. Notably, self-reported measures of cognitive ability, including attention and distractibility, suggest that participants were not aware of the cognitive improvement from meditation. 

    According to the authors, they are among the first to measure cognitive improvements from mindfulness using a reliable eye task in addition to self-reporting surveys. Future work may probe whether longer-term mindfulness interventions strengthen the effects observed in this study. 

    Source:

    Journal reference:

    Kim, A. J., et al. (2025) The Effects of Mindfulness Meditation on Mechanisms of Attentional Control in Young and Older Adults: A Preregistered Eye Tracking Study. eNeuro. doi.org/10.1523/ENEURO.0356-23.2025

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  • Unlocking network APIs’ potential: A Deutsche Telekom perspective

    Unlocking network APIs’ potential: A Deutsche Telekom perspective

    Unlocking network APIs’ potential: A Deutsche Telekom perspective

    Chathurangi Wickramasinghe, SVP Magenta API Capability Exposure (MACE) at Deutsche Telekom, who shares how the operator is collaborating with other telcos and partners to simplify network API access for developers. Interviewed by Joanne Taaffe, Editor-in-Chief at TM Forum, Wickramasinghe outlines a strategy focused on standardization, secure integration, and scalable innovation and explores use cases that can help unlock the full potential of telecom networks

    Chathurangi Wickramasinghe

    SVP Magenta API Capability Exposure (MACE)

    Deutsche Telekom

    Joanne Taaffe

    Joanne Taaffe

    Editor in Chief, Inform

    TM Forum

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  • How are aid cuts impacting child vaccines? The IRC’s critical response

    How are aid cuts impacting child vaccines? The IRC’s critical response

    Right now, global funding for humanitarian aid is facing unprecedented cuts. In 2024 alone, there was a staggering $25 billion shortfall between the funds needed for United Nations appeals and the contributions received.

    In a major setback to global humanitarian efforts, in early 2025 the U.S. State Department—once the world’s largest aid donor—terminated more than 10,000 foreign aid grants and contracts. This has had far-reaching consequences, including the disruption of many lifesaving vaccination programs.

    These cuts come at a time when millions of children in conflict and crisis-affected areas already lack access to critical immunizations, remaining at risk simply because national health systems can’t reach them.

    The funding crisis deepens 

    Recent policy shifts have impacted vaccination funding around the world, including those led by Gavi, the Vaccine Alliance. 

    Infectious disease outbreaks cost an estimated $60 billion per year globally. These outbreaks know no borders and can impact us all. In contrast, disease prevention through vaccination and routine immunization, particularly when delivered by frontline actors, have proven to be highly effective.

    The impact of aid cuts on immunization

    Of the 13 countries the IRC has identified as the most affected by global aid cuts, 10 rank among the bottom 20 globally for measles immunization rates, highlighting a critical gap in disease prevention. This issue is even more alarming as climate change continues to heighten the risks of infectious diseases, further compromising global health efforts.

    Due to these funding cuts, 300 IRC-supported health facilities have closed or are at risk of closing. 

    The IRC provides about 4.3 million services for communicable diseases around the world—1.7 of these services are delivered to children under 5. These services are essential for preventing and controlling outbreaks in vulnerable communities. Critical immunization programs in Burkina Faso, Nigeria, and Afghanistan are all facing the threat of closure.

    Nearly 80% of outpatient visits at the IRC’s 3,300 health facilities worldwide are for infectious diseases. Our programs are integral to helping vulnerable groups survive and to stop diseases from spreading.

    Photo: Karl Bergbom for the IRC

    A global health security threat

    “Preparing for the next pandemic starts by investing where outbreaks begin,” says Dr. Mesfin Teklu Tessema, Senior Director of Health at the IRC. “Global health security is not a luxury. It is a strategic imperative—one that demands sustained, coordinated investment.”

    Cutting vital immunization programs – as well as primary healthcare services- increases the risk of infectious disease outbreaks that could impact everyone. Without prevention and treatment efforts, diseases are more likely to spread unchecked, mutate and become harder to control.

    With 21 million children around the world currently under-immunized, reaching these underserved communities is critical to preventing outbreaks that threaten both regional and global health security.

    The IRC’s solution: Access to life-saving vaccines for children in missed communities

    The IRC is committed to ensuring children receive a full schedule of life-saving vaccines, making immunization a cornerstone of its child health programs. In 2024 alone, over 700,000 children under the age of one were protected against vaccine-preventable diseases by receiving their third dose of the diphtheria, tetanus, and pertussis (DTP) vaccine. This vital protection allows these children to grow up healthier and free from the threat of preventable illnesses.

    To expand access to essential healthcare, including immunizations, the IRC has implemented strategic initiatives designed to maximize the impact of its efforts. These programs focus on reaching children in some of the world’s most fragile and conflict-affected regions, ensuring even the most vulnerable populations can access the care they need. 

    In 2022, the IRC launched the Reaching Every Child in Humanitarian Settings (REACH) project in partnership with Gavi, the Vaccine Alliance. The aim: leverage the IRC’s unique humanitarian expertise to ensure that even the hardest-to-reach children receive the full national schedule of vaccines. 

    Using flexible methods like mobile clinics, local community teams, and mapping tools, our teams are able to reach people in places where the government health system can’t work properly because of conflict, danger, or climate-related problems.

    Since its launch, the REACH consortium has enabled health workers to administer over 13 million vaccine doses to children across the Horn of Africa, with recent extension into Chad and Nigeria.

    An IRC nurse attends to a child during an IRC community outreach program in Turkan, Kenya.

    An IRC nurse, Nancy, attends to Selina Naoi’s* child, Maria*, during an IRC community outreach program in Turkan, Kenya.

    Photo: Billy Mutai for the IRC

    Reaching children at the last mile

    Using flexible and evidence-based interventions enables us to reach more children with essential vaccines, while ensuring maximum impact per dollar spent. Training and supporting community health workers with local knowledge is central to this approach. In 2024, the IRC supported 15,800 community health workers to help ensure more children are protected by lifesaving vaccines.

    In South Sudan, we worked with community health workers and local leaders to raise awareness about vaccines for diseases like polio, measles and diphtheria. Community health workers were also empowered to share community feedback with health officials and help combat misinformation. 

    IRC staff in South Sudan traverse through a flooded village to reach children with vaccinations in Koch County.

    IRC staff in South Sudan traverse through a flooded village to reach children with vaccinations in Koch County.

    Photo: International Rescue Committee

    How can you support vital vaccine programs?

    Now, more than ever, your support is urgently needed to help humanitarian organizations continue to deliver lifesaving services. 

    The new era of reduced aid will bring difficult decisions. But by investing in IRC’s Primary Healthcare Programs that deliver immunization services that center proven interventions, empower local responders, and implement smart financing strategies, we can ensure that available resources have the maximum impact for those most in need.

    With collective action, we can prevent this funding crisis from becoming an era of unprecedented suffering and instead set a path toward sustainable relief and long-term resilience for the world’s most vulnerable populations.

    Donate: Financial contributions are key for trusted organizations like the IRC that prevent, treat and contain infectious diseases. Your donation can empower our work in the U.S. and more than 40 countries worldwide.

    Get connected: Follow our InstagramLinkedInFacebook, and Bluesky accounts.

    Stay informed: Subscribe to IRC alerts to get the latest on our programming and learn more about how you can make a difference.

    Our continued commitment to delivering vital health care

    Every child deserves the right to health care and protection, regardless of crisis. But due to aid cuts, vulnerable children who are relying on humanitarian aid to survive, could be left with nothing. This is a matter of life or death.

    With over 90 years of experience, the IRC knows how to push through tough times by focusing on what matters most—helping those in crisis, working hand-in-hand with communities and treating people with dignity. Our commitment to supporting the hardest-to-reach communities with lifesaving immunization will not waver.

    *Names changed for privacy reasons.


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