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Warriors' 2025 Draftees Share Court for First Time in Summer League Loss to Heat – NBA
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Research explains why promising cancer treatments trigger serious side effects-Xinhua
SYDNEY, July 9 (Xinhua) — Research is shedding new light on the causes of serious side effects linked to some promising cancer treatments.
Scientists have discovered that the protein MCL-1, a key target in cancer drug development, plays not only a role in preventing cell death in cancer cells but also supplying energy to normal cells, according to a statement released Tuesday by Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne.
As a result, drugs that inhibit MCL-1 can inadvertently damage healthy tissues that rely on this protein for energy, especially in organs with high energy demand like the heart and liver, leading to the severe side effects observed in clinical trials, WEHI said.
The new findings clarify that these side effects may be linked to the protein’s critical role in cellular energy production, which enables the development of safer, more targeted cancer therapies that reduce harm to healthy tissues while staying effective against cancer.
“If we can direct MCL-1 inhibitors preferentially to tumor cells and away from the cells of the heart and other healthy tissues, we may be able to selectively kill cancer cells while sparing healthy tissues,” said the study’s co-senior researcher Andreas Strasser, a WEHI laboratory head.
The study, published in Science, also paves the way for safer combination therapies by enabling smarter dosing and pairing of MCL-1 inhibitors with other treatments to reduce toxicity. ■
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Court tells Berlin to honour visa pledges to Afghans – Newspaper
BERLIN: A German court ruled on Tuesday that the government is obliged to issue visas to Afghan nationals and their family members who were accepted into a humanitarian admissions programme that the new centre-right coalition intends to shut down.
A foreign ministry official said the government was reviewing the decision, which is not yet legally binding. After the hasty withdrawal from Afghanistan in 2021 by Western allies, Germany established several programmes to resettle local staff as well as particularly vulnerable Afghans.
Since May 2021, Germany has admitted about 36,500 vulnerable Afghans including former local staff by various pathways. Some 2,400 Afghans approved for admission are waiting in Pakistan to travel to Germany without a clear idea of when, as the programme has been suspended pending a government review, the foreign ministry in Berlin said this month. The court decision, in response to an urgent appeal by an Afghan woman and her family, ruled that the government was legally bound to honour its “irrevocable” commitment to them.
“The applicants assert that they are entitled to a visa and can no longer remain in Pakistan. They face deportation to Afghanistan, where they fear for their lives,” it said.
However, the government is within its rights to end the programme for Afghans and refrain from issuing any new admission commitments going forward, according to the court in Berlin.
NGOs have said that an additional 17,000 Afghans are in the early stages of selection and application under the now-dormant scheme.
Published in Dawn, July 9th, 2025
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200-million-year-old flying reptile species found in Arizona – Newspaper
WASHINGTON: Scientists have unearthed in Arizona fossils from an assemblage of animals, including North America’s oldest-known flying reptile, that reveal a time of transition when venerable lineages that were destined soon to vanish lived alongside newcomers early in the age of dinosaurs.
The remains of the pterosaur, roughly the size of a small seagull, and the other creatures were discovered in Petrified Forest National Park, a place famous for producing fossils of plants and animals from the Triassic Period including huge tree trunks. The newly found fossils are 209 million years old and include at least 16 vertebrate species, seven of them previously unknown.
The Triassic came on the heels of Earth’s biggest mass extinction 252 million years ago, and then ended with another mass extinction 201 million years ago that wiped out many of the major competitors to the dinosaurs, which achieved unquestioned supremacy in the subsequent Jurassic period. Both calamities apparently were caused by extreme volcanism.
The fossils, entombed in rock rich with volcanic ash, provide a snapshot of a thriving tropical ecosystem crisscrossed by rivers on the southern edge of a large desert. Along with the pterosaur were other new arrivals on the scene including primitive frogs, lizard-like reptiles and one of the earliest-known turtles — all of them resembling their relatives alive today. This ecosystem’s largest meat-eaters and plant-eaters were part of reptile lineages that were flourishing at the time but died out relatively soon after. While the Triassic ushered in the age of dinosaurs, no dinosaurs were found in this ecosystem, illustrating how they had not yet become dominant.
“Although dinosaurs are found in contemporaneous rocks from Arizona and New Mexico, they were not part of this ecosystem that we are studying,” said paleontologist Ben Kligman of the Smithsonian Institution’s National Museum of Natural History in Washington, who led the study published in the journal Proceedings of the National Academy of Sciences.
“This is peculiar, and may have to do with dinosaurs preferring to live in other types of environments,” Kligman added. This ecosystem was situated just above the equator in the middle of the bygone supercontinent called Pangaea, which later broke apart and gave rise to today’s continents.
Pterosaurs, cousins of the dinosaurs, were the first vertebrates to achieve powered flight, followed much later by birds and bats. Pterosaurs are thought to have appeared roughly 230 million years ago, around the same time as the earliest dinosaurs, though their oldest-known fossils date to around 215 million years ago in Europe.
The newly identified pterosaur, named Eotephradactylus mcintireae, is thought to have hunted fish populating the local rivers. Its partial skeleton includes part of a tooth-studded lower jaw, some additional isolated teeth and the bones of its elongated fingers, which helped form its wing apparatus. Its wingspan was about three feet (one meter) and its skull was about four inches (10 cm) long. It had curved fangs at the front of its mouth for grabbing fish as it flew over rivers and blade-like teeth in the back of the jaw for slicing prey. The researchers said Eotephradactylus would have had a tail, as all the early pterosaurs did.
Published in Dawn, July 9th, 2025
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Sherry urges shared action to tackle ‘climatic polycrisis’ – Newspaper
ISLAMABAD: The chairperson of the Senate Standing Committee on Climate Change, Senator Sherry Rehman, has urged collective climate action to address the cascading polycrisis.
Speaking at the conference on ‘Pakistan’s Final Warning: Climate Calamity or Collective Action’, the PPP senator said that despite unprecedented climate shocks, there was a troubling silence in policy corridors.
“I see no alarm bells ringing anywhere in power corridors. No budgets are being recalibrated for coping better with the crisis,” she noted.
“If there is one priority for collective climate action in Pakistan it has to be water conservation. The water crisis means we have either too much water in the system and rivers at the wrong time, or too little when and where we need it, to sustain food security and livelihoods across the country.
Pakistan, she noted, is deeply underprepared for the scale of climate investment required: “To meet the climate crisis head on, everything will have to be scaled up. Finance is just one part of it. And let’s be clear — it’s not coming in anywhere close to the quantum needed by frontline ecosystems like ours.”
She also reminded the international community of their responsibilities and stressed the importance of public-private partnerships.
Published in Dawn, July 9th, 2025
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Trump upbeat as Gaza ceasefire talks resume – World
• Negotiators are ‘certainly working’ on truce, Netanyahu tells reporters
• Qatar insists ‘we will need time’ for ceasefire
• Palestinian official says no breakthrough achieved so farDOHA: Indirect Gaza ceasefire talks resumed on Tuesday in Qatar, while Israeli Prime Minister Benjamin Netanyahu visited Washington to meet US President Donald Trump, who expressed optimism about a possible breakthrough.
Qatar, a mediator along with the United States and Egypt, said the meetings were focused on a “framework” for the talks. Qatar said negotiations for a ceasefire between Israel and Hamas are continuing but “need time”.
A fresh round of indirect talks, after 21 months of fighting in Gaza Strip, began on Sunday, with Qatar’s foreign ministry spokesman Majed al-Ansari confirming discussions had gone into a third day.
“I don’t think that I can give any timeline at the moment, but I can say right now that we will need time for this,” Majed Al-Ansari told reporters at a regular briefing, when asked if a deal was close.
“Indirect negotiations are continuing this morning in Doha, with a fourth meeting being held… the discussions are still focused on the mechanisms for implementation, particularly the clauses related to withdrawal and humanitarian aid,” a Palestinian official close to the talks told AFP.
“No breakthrough has been achieved so far, and the negotiations are ongoing,” another Palestinian official said.
Israel and Hamas began the latest round of negotiations on Sunday, with representatives seated in separate rooms within the same building.
Netanyahu’s trip to Washington is his third visit since Trump’s return to office. On Monday, Trump expressed confidence a deal could be reached.
“I don’t think there is a hold-up. I think things are going along very well,” Trump told reporters when asked what was preventing an agreement.
Sitting across from Netanyahu at the White House, Trump said Hamas was willing to end the Gaza conflict, now entering its 22nd month.
“They want to meet and they want to have that ceasefire,” Trump said when asked if ongoing clashes would derail talks.
Trump’s special envoy Steve Witkoff was set to join the talks in Doha this week.
Trump-Netanyahu meeting
Trump and Netanyahu will meet again on Tuesday evening to discuss Gaza, a day after they met for hours while officials conducted indirect negotiations on a US-brokered ceasefire.
Netanyahu spent much of Tuesday at the US Capitol, telling reporters after a meeting with House of Representatives Speaker Mike Johnson that while he did not think Israel’s campaign in the Palestinian enclave was done, negotiators are “certainly working” on a ceasefire.
“We have still to finish the job in Gaza, release all our hostages, eliminate and destroy Hamas’ military and government capabilities,” Netanyahu said.
Shortly after Netanyahu spoke, Steve Witkoff said he hoped to reach a temporary ceasefire agreement this week.
“We are hopeful that by the end of this week, we’ll have an agreement that will bring us into a 60-day ceasefire. Ten live hostages will be released. Nine deceased will be released,” Witkoff told reporters at a meeting of Trump’s Cabinet.
An Israeli official accompanying Netanyahu to Washington said the proposal under discussion was “80-90 per cent of what Israel wanted”. “I believe that with military and political pressure,” all the prisoners can be returned, the official told Israeli media.
According to Ariel Kahana of Israel Hayom daily, “President Trump and his advisers are currently exerting considerable effort to reach an agreement” that would lead to the release of the prisoners and could even end the war in Gaza.
However, far-right National Security Minister Ben Gvir opposed negotiations with Hamas, saying that “there is no need to negotiate with those who murder our fighters; they must be torn to shreds”.
While Israel has the full backing of the Trump administration, the US leader has increasingly pushed for an end to what he called the “hell” in Gaza and said on Sunday he believes there is a “good chance” of an agreement this coming week. “The utmost priority for the president right now in the Middle East is to end the war in Gaza and to return all of the prisoners,” White House Press Secretary Karoline Leavitt said.
Published in Dawn, July 9th, 2025
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Notices issued on plea for FIR over Lyari building collapse – Newspaper
KARACHI: A sessions court on Tuesday sought a report from police on an application seeking registration of an FIR against the city mayor, director general of the Sindh Building Control Authority (SBCA) and others over the collapse of a five-storey building in Lyari last week.
Advocate Muhammad Haroon has filed the application under Sections 22-A and 22-B of the criminal procedure code (CrPC) for registration of an FIR against Mayor Murtaza Wahab, the SBCA chief, heads of utility companies and officials of other public departments for their alleged wilful misconduct and “criminal negligence” in connection with the collapse of the Lyari building.
The applicant also requested the formation of a joint investigation team (JIT) under the supervision of the court to probe a “pattern of illegal constructions, building collapses, forged approvals and loss of life across Karachi”.
After a preliminary hearing, the additional district and sessions judge (South) issued notices to the SSP complaint cell (South) and the SHO of the Baghdadi police station to submit their respective reports.
Referring to the tragic incident in which at least 27 people lost their lives and several others sustained injuries, the applicant contended that an FIR should be registered under relevant sections of the Pakistan Penal Code (PPC) against officials of public departments responsible for enforcing building safety regulations, as well as those who approved utility connections from K-Electric, Sui Southern Gas Company, Sindh Environmental Protection Agency and others.
He also held the fire department responsible for failing to conduct inspections or ensure emergency access in high-density areas.
The applicant alleged that, despite repeated written complaints by residents, no action was taken by the SHO of the concerned police station or the SSP South, claiming that police officials had been “routinely providing protection to builders and land grabbers involved in illegal constructions.”
He also claimed that it was a matter of public knowledge that bribes were allegedly collected by police officials and SBCA personnel on a per-floor basis to permit unlawful vertical expansion.
“These systemic corrupt practices have directly contributed to repeated building collapses, including the tragic incidents in Lyari, Ranchor Line, and Usmanabad,” he submitted.
Citing a Supreme Court ruling in a suo motu case on illegal construction in Karachi, the applicant asked the court to direct the police to record his statement and register an FIR against the proposed accused.
Published in Dawn, July 9th, 2025
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Three killed in north Lebanon strike – Newspaper
BEIRUT: Lebanon said three people were killed on Tuesday in a strike near Tripoli that the Israeli military said targeted a Hamas fighter, the first on the north since a November ceasefire with Hezbollah.
The strike came amid ceasefire negotiations between Israel and Hamas in Qatar and as five Israeli soldiers were killed in combat in the Gaza Strip, one of the deadliest days for Israeli forces in the Palestinian territory this year.
Israel has kept up its strikes on Lebanon despite the November truce, mainly hitting what it says are Hezbollah targets but also occasionally targeting Hamas.
“A short while ago, the (Israeli military) struck a key Hamas fighter in the area of Tripoli in Lebanon,” the Israeli army said.
Lebanon’s health ministry said the strike on a vehicle “killed three people and wounded 13”.
Published in Dawn, July 9th, 2025
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Maryam inaugurates GPO underpass, flyover in Pindi – Newspaper
RAWALPINDI: Punjab Chief Minister Maryam Nawaz on Tuesday inaugurated the General Post Office (GPO) underpass on the Mall and the Nawaz Sharif Flyover on Adiala Road.
The work on the Nawaz Sharif Flyover started in January and its initial cost was Rs2.1 billion, which later escalated to Rs3.6 billion. The work on the GPO underpass started in February for Rs4.6 billion.
In a briefing, the CM was informed that 67 road projects, stretching up to 607 kilometres, had been launched in Rawalpindi, out of which 51 had been completed.
The newly inaugurated Nawaz Sharif Flyover, which starts from Kutchery Chowk on Adiala Road, will benefit traffic passing through GT Road, Ring Road, and the Chakri Interchange on the Motorway.
It was further apprised in the briefing that the traffic from Gorakhpur, Adiala, Khalsa Khurd, Khalsa Kalan, Dhalan, Jarrar Camp, Dhok Awan, and other surrounding localities will benefit from the flyover. A two-kilometre service road has also been constructed around the Nawaz Sharif Flyover.
The CM was informed that for the first time, the latest intelligent signal systems had been installed as part of the GPO Underpass project. The nearly two-kilometre-long underpass will provide easy access to the National Highway N-5 via Kashmir Road. It was further apprised in the briefing that the GPO underpass will also facilitate millions of patients coming to the CMH, MH, and AFIC.
At the inauguration ceremony, Chief Minister Maryam Nawaz also announced that the government would launch clean drinking water projects across Punjab. She announced potable water projects for south Punjab and Potohar. The chief minister also hinted at the early resolution of the water supply problem in Murree, besides the preparation of a project for the construction of an expressway along Leh Nullah in Rawalpindi.
She said, “…the Nawaz Sharif Flyover project will reduce the travel time from Rawalpindi to Chakri by one hour. Most of the road construction and rehabilitation projects have been completed in Rawalpindi.”
According to the CM, the Punjab government has constructed and repaired 12,000 km of roads, and within a few weeks, 19,000 km of roads will be repaired and rehabilitated across the province.
She maintained, “People acknowledge that roads are being built in a record period, it seems as if giants are working. Roads which had not been built for the last 30 years have been built now.”
She congratulated the relevant official for ensuring the timely completion of the Nawaz Sharif Flyover and the GPO underpass. “This project, which will facilitate the plying of two lakh vehicles daily, has been made state-of-the-art,” she added.
The CM also said that the Rawalpindi Ring Road would be completed in record time. “All schools in Rawalpindi are being revamped and will be completed soon. I am personally monitoring the beautification projects of Rawalpindi city,” she added.
More than 1250 health centres across Punjab have been revamped and turned into mini hospitals. The condition of hospitals has entirely changed in a record period of time,” she added.
The CM also highlighted the ‘Suthra Punjab’ project, saying commendable work was being carried out across the province under this project.
“When visitors reach Barian (in Khyber Pakhtunkhwa) from Murree, where the jurisdiction of Punjab ends, a visible difference in cleanliness and infrastructure is witnessed,” she elaborated.
She emphasised that teamwork had become their distinguishing feature in Punjab. The entire team worked with dedication and devotion during Muharram, which was appreciated by the public, particularly the Shia community.
Published in Dawn, July 9th, 2025
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Peshawar High Court halts oath of two women MPAs-elect – Pakistan
• Peshawar High Court orders ECP to modify notification of women seats in KP Assembly
• Sets aside notification declaring JUI-F’s Gorpal Singh minority lawmaker
• IHC also issues notice to Election Commission over KP reserved seatsPESHAWAR: The Peshawar High Court (PHC) on Tuesday barred two women MPAs-elect of the Khyber Pakhtunkhwa Assembly from taking oath and directed the Election Commission of Pakistan (ECP) to modify its last year’s notification on the allocation of these seats.
A two-member bench comprising Justice Syed Arshad Ali and Justice Dr Khurshid Iqbal also set aside the ECP’s notification dated March 26, 2024, which had declared Jamiat Ulema-i-Islam Fazl (JUI-F) candidate Gorpal Singh as MPA-elect on a seat reserved for non-Muslims in the KP Assembly.
The court directed the ECP to reallocate reserved seats for women and non-Muslims within 10 days in accordance with the law, after hearing all relevant political parties, their representatives and contesting candidates.
Until the ECP issues a new decision, the bench ordered that the oath should not be administered to JUI-F MPAs-elect Naheeda Noor and Arifa Bibi, who were elected on the disputed seats.
The bench issued a short order on a petition filed by the PML-N through its KP President Amir Muqam, who challenged two ECP notifications dated March 4 and March 26, 2024. These notifications declared candidates from various parties as MPAs-elect on reserved seats for women and non-Muslims.
The PML-N argued that both it and JUI-F had seven MPAs in the KP Assembly, but while PML-N received eight reserved seats for women, JUI-F was allotted 10. On the non-Muslim seats, JUI-F was granted two out of four seats, whereas PML-N was allocated only one.
The petition also challenged the ECP’s cut-off date of Feb 22, 2024, for independent MPAs to join political parties, after which reserved seat allocations were made.
The bench declared that the ECP’s use of the Feb 22 date for allocating reserved seats was illegal and contrary to the mandate of Article 106 of the Constitution, Sections 18 and 104 of the Elections Act 2017, and Rule 92 of the Elections Rules 2017.
The bench pointed out that the electoral college for reserved seats must include all members of political parties, as well as independent candidates who have joined parties, as of the actual date of election or allocation of the reserved seats.
A panel of lawyers, including Aamir Javed, Saqib Raza and Syed Inayat Shah, appeared for the petitioner and stated that the PML-N had initially won five seats in the Feb 8 general elections, and two independents later joined it.
Mr Javed said that the ECP allegedly calculated reserved seat allocations based on only six MPAs rather than seven. He noted that although an independent MPA joined PML-N on Feb 22, the same day he was officially notified as an MPA-elect, the ECP did not include him in the final seat tally.
Initially, the ECP allocated five women’s seats on Feb 22 — two each to PML-N and JUI-F, and one to PPP. On March 4, it issued a second notification for the remaining 21 seats, resulting in JUI-F receiving a total of 10 reserved seats and PML-N eight.
As for the four seats reserved for non-Muslims, one each was initially allocated to JUI-F, PML-N and PPP. The petitioner contended that the fourth seat should have been decided through a draw between JUI-F and PML-N, but the ECP unilaterally awarded it to JUI-F candidate Gorpal Singh.
The ECP was represented by Special Secretary Zafar Iqbal, legal counsel Mohsin Kamran Siddique, Special Secretary (Law) Mohammad Arshad and Deputy Director Saima Tariq Janjua. Advocate Naveed Akhter appeared for JUI-F and argued that his party had not been made a respondent in the petition despite being directly affected.
IHC issues notice to ECP
The Islamabad High Court (IHC) on Tuesday also issued a notice to the ECP on a petition filed by Pakistan Tehreek-i-Insaf Parliamentarians (PTI-P), seeking suspension of the ECP’s July 2 notification allocating 21 reserved seats in the Khyber Pakhtunkhwa Assembly.
Justice Raja Inaam Ameen Minhas heard the plea. PTI-P’s legal team, comprising Advocates Sultan Muhammad Khan and Tufail Shahzad, appeared in court alongside the party’s Central Secretary General Malik Habib Noor.
Advocate Khan argued that the ECP’s notification was based on flawed calculations and had deprived PTI-P, founded in 2023 by the former KP chief minister Pervez Khattak, of its lawful share of reserved seats. He maintained that the party should have received additional seats based on its performance in the Feb 8 general elections.
Justice Minhas inquired whether any court had suspended the notification. The lawyer confirmed that no stay had been granted so far. The court declined to suspend the notification immediately but issued a notice to the ECP to submit a response and adjourned the hearing.
PTI-P argued that allowing lawmakers elected through the disputed notification to take oath would cause “irreversible prejudice” and undermine the party’s main petition.
The party contended that the ECP’s March 4, 2024, notification erroneously recorded PTI-P as having secured only one general seat in KP, whereas it had actually won two — PK-73 and PK-103. This misrepresentation allegedly cost the party at least three reserved seats.
The matter was also earlier under review in the PHC, which had granted a stay on the oath-taking of MPAs on reserved seats. However, after a two-member PHC bench raised questions about the petition’s maintainability in light of similar proceedings at the IHC, PTI-P withdrew its petition from the PHC, resulting in the dismissal of the case and recall of the stay order.
Malik Asad in Islamabad also contributed to this report
Published in Dawn, July 9th, 2025
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