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Living in microgravity changes the human body — and usually for the worse. Bone density decreases, muscles atrophy, and eyes swell, to name a few of the physical side effects of long-duration spaceflight. However, according to a new study, there’s some good news for astronauts: Spending extended time on the International Space Station (ISS) doesn’t pose any risks to their arteries.

Researchers studied 13 NASA astronaut volunteers, ranging in age from the late 30s to late 50s, who spent between four months and a year on the ISS. They took ultrasound images of the participants’ carotid and brachial arteries before, during and immediately after spaceflight, as well as at the one-, three-, and five-year marks following spaceflight. And, wonderful news — everyone’s arteries looked great.

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NASA has selected University of Hawaiʻi at Mānoa scientists to lead one of three teams developing instruments for Moon travel through the Artemis campaign. Two instruments, including UH’s, will be integrated onto a Lunar Terrain Vehicle (LTV), which astronauts will drive on the Moon. Another instrument will orbit the Moon.

“I’m so excited to see this project come into reality,” said Matthew Siegler, associate researcher in the Hawaiʻi Institute of Geophysics and Planetology (HIGP) at the UH Mānoa School of Ocean and Earth Science and Technology, who will lead the team developing the Lunar Microwave Active-Passive Spectrometer (L-MAPS). “UH has become a major player in the search for ice on the Moon. This instrument selection takes us to the next level.”

The L-MAPS instrument will help determine what is below the Moon’s surface, the heat production of the Moon and search for possible locations of buried ice. The UH science and spacecraft engineering team will work in partnership with instruments developed at NASA’s Jet Propulsion Laboratory (JPL) and the German Technical University at Dresden.

Siegler and deputy principal investigator Shannon Brown, a researcher at JPL, and their team have been designing and testing the L-MAPS instrument for more than five years, preparing for an opportunity to get to the Moon. Being selected for the LTV instrument team moves the development to the next stage—the build—which will primarily take place at JPL.

Outfitting the first crew-driven vehicle on the Moon in 50 years

The LTV vehicle is part of NASA’s efforts to explore the lunar surface as part of the Artemis campaign and is the first crew-driven vehicle to operate on the Moon in more than 50 years. Designed to hold up to two astronauts, as well as operate remotely without a crew, this surface vehicle will enable NASA to achieve more of its science and exploration goals over a wide swath of lunar terrain.

In the NASA announcement, Nicky Fox, associate administrator, Science Mission Directorate at NASA Headquarters in Washington, D.C., emphasized that the Artemis Lunar Terrain Vehicle will advance humanity across the lunar frontier toward exploration and discovery and added that the instruments planned for the LTV combine the best of human and robotic exploration.

When combined, data from the L-MAPS and other instruments will paint a picture of the components of the lunar surface and subsurface to support human exploration and will uncover clues to the history of rocky worlds in our solar system.

“I feel incredibly lucky to be working on lunar research in a time when NASA has prioritized the Artemis return of humans to the Moon,” said Siegler. “Work like this is possible because of researchers at the University of Hawaiʻi working for years leading in planetary science and developing spaceflight technologies. It is exciting to be in the right place and time to ride this wave.”

Collaboration is key to success

At JPL, the L-MAPS instrument will be built with components from Deutsches Zentrum für Luft- und Raumfahrt and Ohio State University. Final testing will be done partially at UH Mānoa. The instrument production and operation on the Moon will be managed by HIGP faculty Miguel Nunes and Trevor Sorensen and will include many roles for UH faculty, undergraduate and graduate students.

—By Marcie Grabowski

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Living in microgravity changes the human body — and usually for the worse. Bone density decreases, muscles atrophy, and eyes swell, to name a few of the physical side effects of long-duration spaceflight. However, according to a new study, there’s some good news for astronauts: Spending extended time on the International Space Station (ISS) doesn’t pose any risks to their arteries.

Researchers studied 13 NASA astronaut volunteers, ranging in age from the late 30s to late 50s, who spent between four months and a year on the ISS. They took ultrasound images of the participants’ carotid and brachial arteries before, during and immediately after spaceflight, as well as at the one-, three-, and five-year marks following spaceflight. And, wonderful news — everyone’s arteries looked great.

“Long-duration spaceflight missions on the ISS did not result in thickening of the carotid artery wall, increased CCA stiffness, endothelial dysfunction, or development of new symptoms or signs of cardiovascular disease in the first 5 years after long-duration spaceflight,” wrote the researchers in their study. They also noted that any risk of cardiovascular disease was likely due to natural aging, not spaceflight.

The study did, however, find oxidative stress and inflammation — signs of concern for the cardiovascular system — in the astronauts’ blood and urine samples. These disappeared within one week of returning to Earth. Ultimately, it seems that the cardiovascular system is quite resilient when it comes to spending time in microgravity.

Of course, this is just one study. As we look toward returning to the moon and establishing a human presence on Mars, we’ll want to continue medical research on astronauts to ensure their long-term health.

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“Continued long-term surveillance of cardiovascular health in the larger astronaut cohort is necessary to characterize the lifetime risk of disease, particularly in astronauts who venture beyond low Earth orbit and are exposed to deep space radiation,” wrote the researchers.

A paper about the research was published on June 10 in the Journal of Applied Physiology.

Earlier this month, astronomers studying the young star V883 Orionis reported spotting complex organic molecules floating in its dusty disk that’s in the process of forming planets.

The discovery hints that life’s chemical toolbox gets stocked well before rocky worlds are even stirred together.

Among the 17 molecular species identified were ethylene glycol and glycolonitrile, both considered stepping stones toward sugars and amino acids.

The project was led by Abubakar Fadul at the Max Planck Institute for Astronomy (MPIA).

Young star named V883 Orionis

V883 Orionis, which is 1,300 light-years away in Orion, is flaring as it gorges on infalling gas, briefly raising parts of its protoplanetary disk above the water-ice line.

That extra warmth liberates chemicals that were frozen onto dust grains, which sends tell-tale radio signals toward Earth.

Using the Atacama Large Millimeter/submillimeter Array in Chile (ALMA), Fadul’s team mapped radiation frequencies between 348 and 366 GHz, isolating 15 emission lines from ethylene glycol and six from glycolonitrile.

The hotter molecule traces gas around 570°F (300°C), while its cooler cousin prefers about 190°F (88°C).

“Our finding points to a straight line of chemical enrichment and increasing complexity between interstellar clouds and fully evolved planetary systems,” said Fadul.

Life molecules freed from ice

Comet observations show that ethylene glycol easily slips from ice when sunlight or mild heat lofts it into space. V883 Orionis supplies the same gentle oven, but on a grander, disk-wide scale.

Glycolonitrile has been detected in dense clouds near the galactic center, proving it can form and survive in harsh stellar nurseries. Its presence in V883 Orionis suggests that survival continues right into the planet-building zone.

In space, ethylene glycol can oxidize into glycolaldehyde, a simple, two-carbon sugar. That sugar was spotted around a young solar-type protostar in Ophiuchus nine years ago.

Laboratory experiments show that glycolonitrile reacts with ammonia to yield glycine, the simplest amino acid, and joins with other nitriles to make adenine, one of DNA’s four bases.

Finding both precursors in the same disk raises the possibility that sugars, acids, and nascent genetic material can migrate together onto pebbles that will seed future planets.

Life’s chemistry in V883 Orionis’ dust

Many researchers believed outbursts and radiation destroyed inherited molecules, requiring disks to completely rebuild their chemistry from scratch. The new observation tilts the debate back toward inheritance.

Spectral surveys of massive, star-forming cores already list more than two hundred organic species, including ethylene glycol and relatives.

Chemical models show methanol, once locked in ice, endures for millions of years in disk midplanes, later feeding bigger molecules such as ethylene glycol.

Because the outburst heats a wide area of the disk, astronomers can track the chemistry across different regions.

These regions will eventually become asteroid belts, icy rings, and zones where giant planets form – offering a preview of the chemical layout in developing planetary systems.

Ancient ice holds life clues

Rosetta’s ROSINA instrument sniffed glycine venting from comet 67P/Churyumov-Gerasimenko in 2016. That find proved that amino acid building blocks can hitch rides on icy bodies that eventually rain down on young planets.

Ethylene glycol has turned up in the tails of comets like Lemmon and Lovejoy, underscoring the match between solar system leftovers and V883 Orionis chemistry.

Comets act as time capsules, preserving the Sun’s protoplanetary ice for 4.5 billion years.

Each molecular match between those relics and faraway disks strengthens the argument that the delivery of life-building organics to young planets is a standard step, not a quirk of our history

Gaps the models must close

Current disk simulations underproduce glycolonitrile, indicating that additional surface pathways, such as UV-driven reactions between formaldehyde, ammonia, and hydrogen cyanide, are still missing.

Adding these energetic routes may also explain why the molecule pops into the gas so readily during stellar flares.

Laboratory studies on cold-grain chemistry continue to improve our understanding of reaction networks.

However, these networks often leave out the latest radiation experiments, forcing scientists to estimate reaction rates that are still poorly measured.

Questions still remain

The ALMA spectra show almost no sign of glycolaldehyde, even though the molecule readily converts to ethylene glycol in laboratory ice studies.

Researchers wonder whether rapid hydrogenation or destruction by hydroxyl radicals keeps the sugar’s signature too faint to see.

Better spectral resolution and follow-up at other wavelengths will help disentangle blended lines and perhaps reveal even heftier organics, from simple peptides to phospholipid precursors.

Scientists still don’t know whether the chemical levels change across the disk or follow patterns called snow lines for each molecule. Answering that question would take sharper images than ALMA can currently provide.

Next steps for V883 Orionis

The team plans to revisit V883 Orionis once the outburst subsides, so that they can compare hot and cold chemistry in the same system. Such time-lapse snapshots could show which molecules linger and which vanish as the disk cools.

Meanwhile, other groups are targeting similar flare-up stars of different ages, aiming to chart a timeline of organic complexity across the journey from interstellar cloud to comet.

Future disk surveys with the upcoming ngVLA will be ten times more sensitive. This could help detect sugars, peptides, and key cell-forming molecules in many star-forming regions.

Planets may start life-ready

If most disks start with a rich stockpile of prebiotic molecules, nascent planets everywhere may inherit a chemical head start on life.

Meteorites that fall to Earth have been found to contain the building blocks of genetic material, like cytosine and uracil. 

Scientists already simulate how comet impacts on young planets like Earth could have delivered the building blocks of life.

Now, they’re extending those simulations to distant star systems like V883 Orionis to see if young planets there could receive similar amounts.

The new ALMA data suggest that delivery service begins well before meteorites form, boosting the odds that rocky worlds across the galaxy begin their stories with similar ingredients.

The study is published in The Astrophysical Journal Letters.

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