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  • Cervical cancer cases on rise in Pakistan

    Cervical cancer cases on rise in Pakistan

    Cervical cancer, one of the most preventable yet deadly diseases, is rising at an alarming rate in Pakistan, where more than 5,000 women are diagnosed and over 3,000 lose their lives each year, as health authorities and international partners now launch the country’s first HPV vaccination campaign in September 2025 to protect millions of girls against the virus.
     
    Pakistan currently has an estimated 68.6 million women aged 15 and older at risk of developing cervical cancer. The disease ranks as the third most common cancer among women in the country and the second most prevalent among women aged 15 to 44. Despite its severity, awareness remains alarmingly low, and stigma surrounding women’s reproductive health discourages many from seeking timely diagnosis and treatment.
     
    The primary cause of cervical cancer is the Human Papillomavirus (HPV). In Pakistan, about 0.5 percent of women in the general population carry HPV types 16 or 18, which account for nearly 88 percent of invasive cervical cancer cases.

    However, late detection has resulted in a staggering mortality rate of 60 to 85 percent, far higher than in many other countries. Medical experts emphasize that regular screening and HPV vaccination are the most effective ways to curb this disease, but these measures have been slow to reach communities.
     
    For years, Pakistan lacked a national strategy to address cervical cancer. Screening programs were inconsistent and largely unavailable in rural areas, where health facilities often lack trained staff and laboratory support. Social taboos around reproductive health further contributed to the underreporting of cases and delayed care. As a result, thousands of women lose their lives each year to a disease that could have been prevented.
     
    To counter this crisis, the government, with support from international health organizations, has launched Pakistan’s first nationwide HPV vaccination campaign. The campaign, beginning in Sindh in September 2025, will target around 4.1 million girls aged 9 to 14, aiming to protect exposure to the virus. Routine vaccination is scheduled to begin in January 2026, with gradual expansion to Punjab, Islamabad, Azad Kashmir, Khyber Pakhtunkhwa, Balochistan, and Gilgit-Baltistan by 2027.
     
    Alongside vaccination, nearly 49,000 health workers are being trained to spread awareness, educate families, and administer vaccines effectively in both urban and rural areas.
     
    Health experts stress that vaccination alone will not be enough. Awareness campaigns, affordable screening, and strengthened cancer registries are equally critical to reducing the national burden. In many cases, women are unaware of the availability of simple tests like PAP smears or HPV screening, while in others, facilities lack the infrastructure to conduct them. Without addressing these systemic gaps, the disease is likely to continue taking lives, particularly in underserved areas.
     
    Cervical cancer is one of the few cancers that can be prevented with vaccines and detected early through screening. In Pakistan, where cultural stigma and health inequities remain barriers, breaking the silence around women’s health is essential.
     
    Each preventable death represents not just a number, but a family torn apart. Public health advocates insist that with the right mix of education, prevention, and care, thousands of lives can be saved, but the time to act is now, before the statistics climb even higher.


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  • Alonso reveals the ‘anonymous’ drive that he ranks as his best in F1 so far

    Alonso reveals the ‘anonymous’ drive that he ranks as his best in F1 so far

    Fernando Alonso has shared the untold story behind what he believes to be his best drive in Formula 1 up to this point, picking out an “anonymous” performance at the Malaysian Grand Prix a decade-and-a-half ago.

    Alonso is the most experienced driver on the F1 grid, having made his debut back in 2001 and racked up 417 starts so far – scoring more than 2,300 points, 106 podium finishes, 32 wins, 22 pole positions and two world titles as of the 2025 Italian Grand Prix.

    However, rather than any of those successes topping his list of greatest races across that period, the 44-year-old Spaniard would go back to the early-2010s and a particularly challenging Sunday afternoon with Ferrari.

    Speaking in an interview with Maaden, a partner of his current team Aston Martin, Alonso instead made reference to the 2010 Malaysian Grand Prix, where race-long gearbox and clutch issues blighted his efforts to recover from 19th on the grid (following a shock Q1 exit amid changeable weather conditions).

    “There are many races that people were not maybe aware of,” said Alonso, reasoning why he did not choose one of his legendary wins, such as the 2012 European Grand Prix in Valencia, which saw him charge from 11th to the top step of the podium.

    “It was Malaysia, Sepang [in 2010], where I had a problem on the gearshift. The gearbox was broken, semi-broken, the clutch had a problem – the gears went up okay, but not down.

    “Around halfway through the race I tried to downshift into Turn 1 and from seventh [gear] I went to only fifth instead of second, so I did Turn 1 in fifth, I lost time, and I realised in the following corner that there was a problem.

    “Out of desperation, I tried to blip the throttle on a downshift, because if not I would retire the car in that lap. I blipped the throttle and the downshift went in, so on the next braking point I blipped the throttle four times and four downshifts [happened].

    “I communicated to the team, ‘What I’m doing is right or wrong? I will break the gearbox within one lap?’ They said, ‘Keep doing what you’re doing, the gearbox is safe by doing that’.

    “I did like 30 laps like that, so the upshift was okay, then braking I had to brake and, while having the pressure on the brake pedal, I had to blip the throttle a couple of times to do the downshifts that I wanted – obviously synchronising the throttle and the paddle shift.”

    An engine failure a couple of laps from the chequered flag left Alonso 13th in the overall classification, without a point to his name, but even today he takes great pride from the performance he was able to deliver while managing so many issues.

    “The engineers said [after the race], ‘I don’t know [how] you came [up] with that solution that fast, because that could be a solution, but you did it like in 13 or 14 seconds, the second corner after you had a problem’,” added Alonso. “I said, ‘I hate losing, I hate retiring the car, I will try everything before accepting that we have to DNF’.

    “[It was] completely anonymous, no one will remember that race, but the level of energy that I had to put [into] that race, the level of concentration, focus, and [to] instinctively come out with a solution [to] a problem that was never tested or experienced… I think it was quite a race to remember.”

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  • Top stocks to watch from analysts include Nvidia, FedEx, UPS, Amazon

    Top stocks to watch from analysts include Nvidia, FedEx, UPS, Amazon

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  • Chashma Sugar Mills Completes Amalgamation with Ultimate Whole Foods

    Chashma Sugar Mills Completes Amalgamation with Ultimate Whole Foods

    Chashma Sugar Mills Limited (CSM) has officially completed its amalgamation with its wholly-owned subsidiary, Ultimate Whole Foods (Private) Limited.

    The announcement was made in a notice submitted to the Pakistan Stock Exchange (PSX).

    The merger, previously approved under the Scheme of Amalgamation, consolidates the operations of the two entities, with Chashma Sugar Mills Limited serving as the transferee company.

    This strategic move is expected to streamline operations, enhance efficiency, and create new growth opportunities for the company.

    Chashma Sugar Mills Limited, headquartered in Islamabad, operates multiple factories in Dera Ismail Khan, including sugar mills and an ethanol fuel plant.

     


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  • Ireland threatens to withdraw from Eurovision if Israel participates

    Ireland threatens to withdraw from Eurovision if Israel participates

    The Irish state broadcaster RTÉ has said it will not take part in the 2026 Eurovision Song Contest “if the participation of Israel goes ahead”.

    In a statement, RTÉ said that Ireland’s participation in the event “would be unconscionable given the ongoing and appalling loss of lives in Gaza”.

    Ireland has won the contest seven times in total, most recently in 1996.

    RTÉ will make a final decision once the Eurovision organisers, the European Broadcasting Union, makes its decision.

    Next year’s contest will be held in May in Vienna.

    Slovenia’s national broadcaster, RTVSLO, has also said it will withdraw from the competition if Israel participates.

    Spain’s Culture Minister Ernest Urtasun has said that his country may also not take part should Israel participate.

    In a statement on Thursday, RTÉ said: “It is RTÉ’s position that Ireland will not take part in the 2026 Eurovision Song Contest, if the participation of Israel goes ahead, and the final decision regarding Ireland’s participation will be made once the EBU’s decision is made”.

    It added: “RTÉ is also deeply concerned by the targeted killing of journalists in Gaza, the denial of access to international journalists to the territory, and the plight of the remaining hostages.”

    Prior to this year’s Eurovision in May, RTÉ asked the EBU for a discussion on Israel’s inclusion in the Eurovision Song Contest.

    At that time, its director general, Kevin Bakhurst, said he was “appalled by the ongoing events in the Middle East and by the horrific impact on civilians in Gaza, and the fate of Israeli hostages”.

    He added that he was mindful of RTÉ’s obligations to maintain objectivity in covering the war in Gaza.

    “We are also very mindful of the severe political pressure on Israel’s public service broadcaster, Kan, from the Israeli government,” he said.

    Earlier this year, more than 70 former Eurovision contestants signed a letter calling on the organisers to ban Israel from the 2025 competition.

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  • Your morning coffee could secretly be weakening antibiotics

    Your morning coffee could secretly be weakening antibiotics

    Ingredients of our daily diet – including caffeine – can influence the resistance of bacteria to antibiotics. This has been shown in a new study by a team of researchers at the Universities of Tübingen and Würzburg led by Professor Ana Rita Brochado. They discovered bacteria such as Escherichia coli (E. coli) orchestrate complex regulatory cascades to react to chemical stimuli from their direct environment which can influence the effectiveness of antimicrobial drugs.

    In a systematic screening, Brochado’s team investigated how 94 different substances – including antibiotics, prescription drugs, and food ingredients – influence the expression of key gene regulators and transport proteins of the bacterium E. coli, a potential pathogen. Transport proteins function as pores and pumps in the bacterial envelope and control which substances enter or leave the cell. A finely tuned balance of these mechanisms is crucial for the survival of bacteria.

    Researchers describe phenomenon as an ‘antagonistic interaction’

    “Our data show that several substances can subtly but systematically influence gene regulation in bacteria,” says PhD student Christoph Binsfeld, first author of the study. The findings suggest even everyday substances without a direct antimicrobial effect – e.g. caffeinated drinks – can impact certain gene regulators that control transport proteins, thereby changing what enters and leaves the bacterium. “Caffeine triggers a cascade of events starting with the gene regulator Rob and culminating in the change of several transport proteins in E. coli – which in turn leads to a reduced uptake of antibiotics such as ciprofloxacin,” explains Ana Rita Brochado. This results in caffeine weakening the effect of this antibiotic. The researchers describe this phenomenon as an ‘antagonistic interaction.’

    “Caffeine triggers a cascade of events starting with the gene regulator Rob and culminating in the change of several transport proteins in E. coli – which in turn leads to a reduced uptake of antibiotics such as ciprofloxacin.” Ana Rita Brochado

    This weakening effect of certain antibiotics was not detectable in Salmonella enterica, a pathogen closely related to E. coli. This shows that even in similar bacterial species, the same environmental stimuli can lead to different reactions – possibly due to differences in transport pathways or their contribution to antibiotic uptake. President Prof. Dr. Dr. h.c. (Dōshisha) Karla Pollmann emphasizes: “Such fundamental research into the effect of substances consumed on a daily basis underscores the vital role of science in understanding and resolving real-world problems.”

    The study, which has been published in the scientific journal PLOS Biology, makes an important contribution to the understanding of what is called ‘low-level’ antibiotic resistance, which is not due to classic resistance genes, but to regulation and environmental adaptation. This could have implications for future therapeutic approaches, including what is taken during treatment and in what amount, and whether another drug or food ingredient – should be given greater consideration.

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  • European Qualifiers for the 2026 World Cup: What to look out for on Matchday 7 and 8 – UEFA.com

    1. European Qualifiers for the 2026 World Cup: What to look out for on Matchday 7 and 8  UEFA.com
    2. What teams are qualified for 2026 World Cup? Full list, latest updates  USA Today
    3. How five-star England thrashed Serbia to extend their 100 per cent World Cup qualifying record – The Athletic  The New York Times
    4. Europe’s Football Giants Battle for World Cup Glory  Devdiscourse
    5. European World Cup qualifying: Spain reigns, Tuchel’s England emerges and Mbappé keeps France steady  ehextra.com

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  • Stroll Through UNESCO’s Gardens for the European Heritage Days

    Stroll Through UNESCO’s Gardens for the European Heritage Days

    On the occasion of the European Heritage Days, UNESCO will open its doors to the public on Saturday 20 September 2025, from 12 p.m. to 6 p.m., for a unique stroll through its gardens and art esplanade.

    Located in the heart of Paris, UNESCO Headquarters is home to a remarkable landscape and artistic heritage, reflecting the dialogue between cultures, nature and contemporary creation.

    A journey through nature and art

    Visitors will be able to discover:

    • The Japanese Garden designed by Isamu Noguchi and recently restored,
    • The meditation space created by Tadao Andō,
    • The Square of Tolerance, a landscape sculpture masterpiece by Dani Karavan,
    • UNESCO’s ecological vegetable garden, a living example of biodiversity and knowledge sharing,
    • The Piazza designed by Roberto Burle Marx, and the esplanade featuring masterpieces of modern art by Joan Miró, Alexander Calder, Henry Moore, Vhils, Eduardo Chillida and many others.

    Set in a green environment conceived as a space for dialogue and peace, this visit offers an immersion into an exceptional landscape heritage, within one of the most iconic examples of brutalist architecture in Paris.

    An outdoor exhibition on the Silk Roads

    The visit continues with the exhibition “Youth Eyes on the Silk Roads”, displayed on UNESCO’s fences, celebrating the cultural richness and diversity of exchanges among peoples.

    👉 For those who wish to explore the interior of UNESCO Headquarters and its emblematic rooms, guided tours are offered throughout the year: unesco.org/en/guided-tours.

    📍 Practical information

    • Date & time: Saturday 20 September 2025, from 12 p.m. to 6 p.m.
    • Venue: Entrance via 7, place de Fontenoy – 75007 Paris

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  • Monsoon 2025: NDMA arranges briefing session for foreign diplomats – RADIO PAKISTAN

    1. Monsoon 2025: NDMA arranges briefing session for foreign diplomats  RADIO PAKISTAN
    2. NDMA briefs foreign missions on Monsoon relief efforts at NEOC headquarters  Associated Press of Pakistan
    3. Parliamentarians visit NEOC to review monsoon response Breaking  Independent News Pakistan
    4. Parliamentary delegation visits NEOC to review monsoon response  Associated Press of Pakistan

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  • DLA Piper advises lenders on landmark USD430 million financing for Genser Energy

    DLA Piper has advised a pool of lenders on the provision of c.USD430 million in financing for Genser Energy Ghana Limited, a leading diversified energy business, marking one of the largest energy sector financings in Ghana in recent years. The funds will be used to refinance existing debt linked to key infrastructure assets in Ghana, including the gas processing plant in Prestea and the natural gas liquids (NGL) storage facility at Takoradi Port, both of which are nearing completion.

    Together with Genser’s network of natural gas pipelines, these facilities will continue to enhance Ghana’s energy infrastructure and play an important role in accelerating the country’s energy transition. Once operational, they will increase the country’s processing and storage capacity, improve energy security, and support industrial growth by providing reliable access to cleaner natural gas.

    The financing deal was completed in under two months and was structured as both a corporate finance loan and a decarbonisation loan. It included USD and EUR tranches alongside an uncommitted accordion facility. Three mandated lead arrangers acted as original lenders, and two additional banks joined before financial close, reflecting strong market confidence in Genser Energy and Ghana’s long-term energy outlook.

    Titus Edjua, partner, commented: “This transaction demonstrates the firm’s commitment to delivering complex cross-border financings at speed while supporting sustainable development and the expansion of critical energy infrastructure in Africa.”

    In addition to Titus, the core team included Senior Associate Shamim Khan (London), Associates Salesh Premjith (London) and Natalie Teoh (London), Trainee Solicitor Jack Ford (London), and Senior Paralegal Ben King (London). Finance Partner Jackie Pennington (Johannesburg) and Associate Thulare Manyaku (Johannesburg) provided support on South African law.

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