Author: admin

  • Apple’s ‘Back to School’ Offer Now Available Across Europe

    Apple’s ‘Back to School’ Offer Now Available Across Europe

    Apple’s annual Back to School offer for university students and educational staff is now available in many European countries, after initially launching in the U.S., Canada, Mexico, Singapore, India, and the United Arab Emirates last month.

    Apple’s online educational store is now showing the limited-time promotional offer in a long list of countries. With the purchase of an iPad, MacBook, or iMac, students can receive an accessory such as the Apple Pencil Pro, AirPods 4, or ‌AirPods 4‌ with Active Noise Cancellation for free. Alternatively, for a fee, customers can upgrade to a pricier accessory while retaining their overall saving.

    The available accessories, savings, and supplementary costs are as follows (UK pricing):

    iPad

    • ‌Apple Pencil‌ Pro (£119.00 savings)
    • ‌AirPods 4‌ (£129.00 savings)
    • ‌AirPods 4‌ with Active Noise Cancellation (£129.00 savings, after paying additional £50.00 fee)
    • AirPods Pro 2 (£129.00 savings, after paying additional £100.00 fee)
    • Magic Keyboard for iPad Air 11-inch (£119.00 savings, after paying additional £130.00 fee)
    • Magic Keyboard for ‌iPad Air‌ 13-inch (£119.00 savings, after paying additional £160.00 fee)
    • Magic Keyboard for iPad Pro 11-inch (£119.00 savings, after paying additional £160.00 fee)
    • Magic Keyboard for ‌iPad Pro‌ 13-inch (£119.00 savings, after paying additional £210.00 fee)

    MacBook

    • ‌AirPods 4‌ with Active Noise Cancellation (£179.00 savings)
    • ‌AirPods Pro‌ 2 (£179.00 savings, after paying additional £50.00 fee)
    • Magic Mouse (£79.00–£99.00 savings)
    • Magic Trackpad (£129.00–£149.00 savings)
    • Magic Keyboard with Touch ID (£179.00–£199.00 savings)

    iMac

    • ‌AirPods 4‌ with Active Noise Cancellation (£179.00 savings)
    • ‌AirPods Pro‌ 2 (£179.00 savings, after paying additional £50.00 fee)

    The offer is now live in the UK, Ireland, France, Germany, Italy, Spain, Portugal, Austria, Belgium, Czechia, the Netherlands, Hungary, Poland, Switzerland, Denmark, Finland, Norway, Sweden, and a few other countries and territories in Europe, as well as in Türkiye.

    The free accessory is included in addition to Apple’s standard year-round 10% educational discount on select Mac and ‌iPad‌ models. In Europe, the promotion ends on October 21. In the U.S., it ends on September 30.

    Continue Reading

  • Jail trial conducted in three May 9 cases

    Jail trial conducted in three May 9 cases

    LAHORE  –  The jail trial of three cases, including the arson attack on Shadman Police Station and torching of police vehicles, during the May 9 riots, continued on Wednesday at Kot Lakhpat Jail under tight security. Administrative Judge of the Anti-Terrorism Court (ATC), Manzer Ali Gill, presided over the proceedings which lasted until 6:30 PM. During the hearing, eight prosecution witnesses recorded their statements against the accused while defence counsel completed cross-examination of five witnesses. The trial proceedings were adjourned until tomorrow for further evidence. Prominent PTI leaders on bail, including Aliya Hamza and Khadija Shah, appeared before the court, while the attendance of detained leaders such as Shah Mahmood Qureshi and Dr. Yasmin Rashid was also marked.


    Continue Reading

  • Kellogg shares soar on reports of Ferrero takeover talks

    Kellogg shares soar on reports of Ferrero takeover talks

    Shares in breakfast cereal giant WK Kellogg have soared after reports that chocolate maker Ferrero is close to buying the firm for about $3bn (£2.2bn).

    Ferrero could finalise the deal for the maker of Fruit Loops and Corn Flakes as soon as this week, the Wall Street Journal and Financial Times reported.

    The Italian owner of the Ferrero Rocher and Kinder brands has been expanding in recent years, buying Nestle’s confectionery business and several other food firms.

    WK Kellogg shares rose by more than 50% in after-hours trading in New York after the reports.

    WK Kellogg and Ferrero did not immediately respond to BBC requests for comment.

    Kellogg has been struggling financially in recent years despite a major shakeup in 2023 that saw it focus solely on breakfast cereals.

    Food firms are facing major challenges as customers shift to healthier options, which has forced them to change the way the operate.

    The industry has also come under pressure from the Trump administration, which has targeted artificial colouring in brands like Fruit Loops as part of its “Make America Healthy Again” campaign.

    Kellogg has said it will remove the synthetic colours from cereals eaten in schools by the 2026-27 school year. But it has not yet set a timeline for taking them out of cereals sold to the general public.

    The company’s founder, Will Keith Kellogg, is widely considered to be the inventor of corn flakes.

    Continue Reading

  • Chinese yuan strengthens to 7.1510 against USD Thursday-Xinhua

    BEIJING, July 10 (Xinhua) — The central parity rate of the Chinese currency renminbi, or the yuan, strengthened 31 pips to 7.1510 against the U.S. dollar Thursday, according to the China Foreign Exchange Trade System.

    In China’s spot foreign exchange market, the yuan is allowed to rise or fall by 2 percent from the central parity rate each trading day.

    The central parity rate of the yuan against the U.S. dollar is based on a weighted average of prices offered by market makers before the opening of the interbank market each business day.

    Continue Reading

  • Nicola Peltz’s brother engaged to Quincy Jones’ youngest daughter

    Nicola Peltz’s brother engaged to Quincy Jones’ youngest daughter

    Nicola Peltz’s brother Will Peltz engaged to Quincy Jones’ daughter Kenya Kinski-Jones

    Nicola Peltz’s older brother, Will Peltz, is engaged to Kenya Kinski-Jones after dating each other for 10 years.

    The 39-year-old actor, who proposed to the daughter of the late Quincy Jones and actress and model Nastassja Kinski, announced the news on Wednesday via a joint Instagram post, featuring a romantic black-and-white photo from the proposal.

    “JUST ENGAGED. My whole heart for my whole life,” wrote Kenya, 32, in the caption and tagged the Lola actor in the photo of them sharing a kiss on a boat.

    Congratulations were in order for the newly-engaged couple, especially from Nicola and her husband, Brooklyn Beckham.

    “KENYA JONES PELTZ!!!!!!! MY FOREVER SISTER!!!! IM SO HAPPY I LOVE YOU BOTH!!!!!” wrote Nicola as she reshared the announcement.

    Nicola Peltzs brother engaged to Quincy Jones youngest daughter

    She also left a sweet comment on the couple’s original post, saying, “KENYA JONES PELTZ! ! ! ! ! ! ! MY FOREVER SISTER! ! ! ! IM SO HAPPY I LOVE YOU BOTH! ! ! ! !”

    Brooklyn, who has been radio-silent on his own family’s celebrations, also congratulated the couple, writing, “Congratulations [Will and Kenya] x love u 2 x so happy for you guys.”

    Brooklyn has grown close to his in-laws in recent months amid speculations of a rift with his parents, David and Victoria Beckham.

    Brooklyn and Nicola’s absence from his family’s recent gatherings further fueled the reports of the quiet rift, allegedly linked to Nicola and Brooklyn’s disapproval of Romeo’s now ex-girlfriend, Kim Turnbull.


    Continue Reading

  • After the Preemptive Strikes on Iran: Evolving Limits of Israel’s Nuclear Ambiguity

    After the Preemptive Strikes on Iran: Evolving Limits of Israel’s Nuclear Ambiguity

    In consequence of recent hostilities, Iran’s prospects for gaining military nuclear capacity have been significantly degraded. Ipso facto, the potential Iranian nuclear threat to Israel has been slowed. Still, these unprecedented prospects have not been removed altogether.  And Iran remains allied with certain state enemies of Israel that are “already nuclear.”

    What should Israel do?

    What ought to be Jerusalem’s next protective steps, whether sudden or sequential?

    Under authoritative international law, the right to take such steps[1] would  be  “peremptory.”[2]

    The correct answers are clear and straightforward. Israel should do what is needed to upgrade and enhance its nuclear deterrence posture. More precisely,this posture, which includes both doctrine and strategy,[3] will depend on Israel’s willingness to substitute “selective nuclear disclosure” for “deliberate nuclear ambiguity.”[4]

     Assorted clarifications are necessary. Reason dictates that Israel does have a “bomb in the basement” (i.e., an operational nuclear military capacity), but that its deliberately ambiguous nuclear deterrent will need core modifications. The overall strategic purpose of a more conspicuous nuclear deterrent would not be to acknowledge the obvious (i.e., that Israel has nuclear weapons), but to emphasize that these weapons are usable at foreseeable levels of military engagement. Plausibly, where a major state adversary did not perceive such “usability,” it would not be adequately deterred.[5]

    It’s high time for candor. Even after Israel’s recent victories over Iran, it would be unreasonable to assume that “deliberate nuclear ambiguity” will work indefinitely. At some not yet determinable point, Iran’s degraded potential to acquire functional nuclear forces could return to status quo ante bellum. By anticipating such peril, a tangible danger that could become force-multiplying in calibrated increments, the Jewish State could best understand something genuinely elemental: In the future, Iranian perceptions of Israeli nuclear credibility will require more rather than less nuclear disclosure.[6]

    At first, this argument may sound naïve or counter-intuitive. Nonetheless, strategic realities in the Middle East should never be extrapolated from simplifying narratives or empty witticisms. To meaningfully identify and calculate these realities will represent a challenging intellectual task, an imperative of the highest order.

    To survive, even after expressly acknowledging nuclear ordinance and nuclear policy, a country smaller that America’s Lake Michigan will require extraordinary strategic thinkers. On existential matters, such unique “minds” could matter much more than courageous military warriors.[7] Looking ahead to the “next war,” Israel’s always-capable warfighters will remain necessary but insufficient.

    For Israel, this is not the time for “common sense.” Among other things, leadership in Jerusalem will need to understand progressively urgent matters of “chronology.” To wit, Iran’s leaders function with a different concept of time than do Israel’s decision-makers.[8] Unambiguously, the Iranian side has subordinated “clock time” (i.e. “profane time”) to “sacred time.”

     There will be tangible correlates. On critical matters of strategic doctrine, Iran maintains a “higher law” obligation not to capitulate to enemy “unbelievers.” Inter alia, leaders in Tehran would never submit to an American president’s demand for “unconditional surrender.” Like it or not, and for as long as it takes, these leaders are fully prepared to “wait.”

    For Israel, Israel’s cumulative stance requires a timely loosening of “deliberate nuclear ambiguity.” Even if Iran’s nuclear potentialities were massively set back by the recent Israeli and American bombardments, there would be other enemy states to worry about. These states could be already-nuclear, pre-nuclear or “merely” non-nuclear adversaries. Relevant examples would be Sunni Arab states (e.g., Saudi Arabia, Egypt), Turkey, or Pakistan. After the just-halted Israel-Iran war, Pakistan explicitly reaffirmed “complete solidarity” with Iran. This declaration included threats of direct nuclear retaliation against Israel if Iran were to face nuclear attack by the Jewish State.[9]

    Another nuclear state ally of Iran is increasingly problematic. North Korea, a geographically distant and non-Islamic state, has a documented history of belligerent interactions with Israel. In principle, at least, a temporarily defanged Iran could call upon an already-nuclear proxy in Pyongyang, and Israel’s survival would then depend on the enhanced credibility of its nuclear deterrent.

                   How do matters stand right now, in the aftermath of a temporarily-halted Israel-Iran war?[10] Using Reason as its sole decisional standard, Israel will need to update its national strategic posture (doctrine and strategy) by shifting from “deliberate nuclear ambiguity” to “selective nuclear disclosure.” Though a resumed war with Iran could become nuclear even while Iran remained non-nuclear, that war would be “asymmetrical” and favor Israel ipso facto.

                    In the future, if Israel remained committed to its “bomb in the basement” nuclear posture, the country’s intra-war opportunities to achieve “escalation dominance”[11] would be severely limited. Even if Tehran were to accept the reality of Israel’s nuclear options, it might not believe that Jerusalem would be willing to actually exercise these options. As a result, a tit-for-tat dynamic of conventional warfare could proceed unabated and Israel might need to face the exhausting prospect of interminable attrition warfare.[12] Already, Iran is planning to buy Chinese Chengdu J-10C fighter jets compatible with PL-15 missiles, the same ordnance used by Pakistan’s air force.

                   There are many complex and intersecting issues. From Israel’s perspective, only “selective nuclear disclosure” could help keep Iran non-nuclear. Unless Israel had somehow managed to persuade Iran that its operational nuclear forces were tactically usable (ironically, this means weapons that are not presumed “too destructive”), Israel’s re-arming adversary could remain committed to ongoing military struggle. Plausibly, such commitment would be hardened by any further Iranian embrace of “martyrdom operations.”

                     Here , antecedent reasoning warrants clarifications. Harboring alternative hopes for regime change in Tehran would be futile and self-deceiving. Among other shortcomings,[13] Iranian regime transformations would always be subject to prompt or incremental reversals.

                    Israel cannot rely forever on an implicit nuclear deterrence posture. Regarding any future or still-impending war with Iran, it is necessary for Israel to consider once- speculative but no longer unrealistic scenarios. Among narrative possibilities, Pakistan and/or North Korea could sometime become nuclear proxies for a non-nuclear Iran. At that stage, any Israeli continuance of “deliberate nuclear ambiguity” would be stubbornly foolish and manifestly self-destructive.

                    Until now, Iran’s hyperbolic threats against Israel have been contrived (“pretended irrationality”). How else could a reason-directed strategist explain a non-nuclear state’s military threats against a nuclear state?  In principle, Israel could “call Iran’s bluff,” but only if its non-nuclear forces were recognizably superior to Iran’s conventional forces and/or Jerusalem had previously made more explicit Israel’s nuclear options.

                   There is more. Israel will need to ensure “escalation dominance” in all realistic conflict scenarios. Ultimately, this means keeping Iran non-nuclear.[14] Though there will be many technical questions on optimal levels and times regarding “selective nuclear disclosure,” this is not yet the right moment for raising such details.

                    Some final clarifications are now in order. Even a pre-nuclear Iran could make combat use of radiation dispersal weapons and/or conventional missiles/drones launched against Israel’s Dimona nuclear reactor. In a worst case scenario, Iranian ally North Korea would place nuclear assets at Tehran’s operational disposal. North Korea has a tangible history of involvement in Middle Eastern military matters. Pyongyang built a nuclear reactor for Syria at Al Kibar that was subsequently destroyed by Israel’s Operation Orchard on September 6, 2007.

    For Israel, even after the dramatic weakening of Iran and its terror-surrogates, the time for “deliberate nuclear ambiguity” is coming to an end. Failure to recognize this inflection point could ensure intermittent or near-continuous warfare with a rearming Iran. Whatever the relative costs, any such conflict would be net-injurious for Israel.

    While it is uncertain that “selective nuclear disclosure” could end Iran’s belligerent designs against Israel, a more selectively-explicit Israeli deterrence posture would represent Jerusalem’s only rational choice. At the same time, even this enhanced doctrine and strategy might not be enough. Jerusalem, with or without its American ally, might still need to launch a new round round of measured preemptive strikes.[15]

    For the moment, Iran is down, but it is not out.


    [1] In law, even if a threatened state has defensible “just cause,” it must still respect corollary obligations of “just means.” These are obligations of the “law of armed conflict” or “humanitarian international law.” In essence, under law, every use of force must be judged twice:  once with regard to the right to wage war (jus ad bellum), and once with regard to the means used in conducting war (jus in bello).  Following the Kellogg-Briand Pact of 1928, and the United Nations Charter, all right to aggressive war has been abolished ipso facto.  However, the long-standing customary right of self-defense remains, codified at Article 51 of the Charter.  Similarly, subject to conformance, inter alia, with jus in bello criteria, certain instances of humanitarian intervention and collective security operations may be consistent with jus ad bellum.  The laws of war, the rules of jus in bello, comprise (1) laws on weapons; (2) laws on warfare; and (3) humanitarian rules.  Codified primarily at The Hague and Geneva Conventions (and known thereby as the law of The Hague and the law of Geneva), these rules attempt to bring distinction, proportionality and military necessity into belligerent calculations.

    [2] According to Article 53 of the Vienna Convention on the Law of Treaties: “…a peremptory norm of general international law is a norm accepted and recognized by the international community of states as a whole as a norm from which no derogation is permitted and which can be modified only by a subsequent norm of general international law having the same character.” See: Vienna Convention on the Law of Treaties, Done at Vienna, May 23, 1969. Entered into force, Jan. 27, 1980. U.N. Doc. A/CONF. 39/27 at 289 (1969), 1155 U.N.T.S. 331, reprinted in 8 I.L.M.  679 (1969).

    [3] In military parlance, strategy is not identical to doctrine. More precisely, doctrine is the framework from which strategic goals should be extrapolated. Generically, in orthodox military thinking, such doctrine describes the tactical manner in which national forces ought to fight in pertinent combat situations, the prescribed “order of battle,” and assorted corollary operations. The literal definition of “doctrine” derives from Middle English, from the Latin doctrina, meaning teaching, learning, and instruction. Always, a central importance of codified military doctrine lies not only in the way it can animate, unify and optimize available military forces, but also in the fashion that it can transmit desired “messages” to a pertinent enemy.

    [4] For an earlier assessment of this distinction by the author, see Louis René Beres at 2013 Herzliya Conference address (Israel): https://www.runi.ac.il/media/soipnf0a/louisreneberes.pdf

    [5] Recall classical nuclear strategist Herman Kahn’s observation in Thinking About the Unthinkable (1962): “Deterrence is not just a matter of military capabilities. It has a great deal to do with perceptions of credibility.”

    [6] On deterring a potentially nuclear Iran, see: Louis René Beres and General John T. Chain, “Could Israel Safely Deter a Nuclear Iran?” The Atlantic, August 2012; and Professor Louis René Beres and General John T. Chain, “Israel and Iran at the Eleventh Hour,” Oxford University Press, February 23, 2012. General Chain (USAF/deceased.) served as Commander-in-Chief, U.S. Strategic Air Command (CINCSAC).

    [7] Examples would be J. Robert Oppenheimer, nuclear thinker Herman Kahn (see epigraph, above) and Yuval Ne’eman. The present author (Louis René Beres) was a long-time friend and colleague of Professor Ne’eman.

    [8] See by this writer at Israel Defense: Louis René Beres, https://www.israeldefense.co.il/en/node/65219

    [9] For early accounts by this author of nuclear war risks and effects, see: Louis René Beres, Apocalypse: Nuclear Catastrophe in World Politics (Chicago: University of Chicago Press, 1980); Louis René Beres, Mimicking Sisyphus: America’s Countervailing Nuclear Strategy (Lexington, Mass., Lexington Books, 1983); Louis René Beres, Reason and Realpolitik: U.S. Foreign Policy and World Order (Lexington, Mass., Lexington Books, 1984); and Louis René Beres, Security or Armageddon: Israel’s Nuclear Strategy (Lexington, Mass., Lexington Books, 1986). Most recently, by Professor Beres, see: Surviving Amid Chaos: Israel’s Nuclear Strategy (New York, Rowman & Littlefield, 2016; 2nd ed. 2018). https://paw.princeton.edu/new-books/surviving-amid-chaos-israel%E2%80%99s-nuclear-strategy

    [10] Under international law, a cease-fire is a temporary cessation of hostilities, not a war-terminating agreement. But when does a formal “state of war” exist between states? In the traditional view, a declaration of war was necessary before any true state of war could exist. Hugo Grotius divided wars into declared wars, which were legal, and undeclared wars, which were not. (See Hugo Grotius, The Law of War and Peace, Bk. III, Chapters. III, IV, and XI.) By the start of the twentieth century, the position that war obtains only after a conclusive declaration of war by one of the parties was codified by Hague Convention III. This treaty stipulated that hostilities must never commence without a “previous and explicit warning” in the form of a declaration of war or an ultimatum. (See Hague Convention III Relative to the Opening of Hostilities, 1907, 3 NRGT, 3 series, 437, article 1.) Currently, declarations of war may be tantamount to admissions of international criminality, because of the express criminalization of aggression by authoritative international law, and it could therefore represent a clear jurisprudential absurdity to tie any true state of war to formal and prior declarations of belligerency. It follows that a state of war may now exist without any formal declarations, but only if there is taking place an actual armed conflict between two or more states and/or at least one of these states considers itself “at war.”

    [11] On “escalation dominance,” see article by Professor Louis René Beres at The War Room, US Army War College, Pentagon:  https://warroom.armywarcollege.edu/articles/nuclear-decision-making-and-nuclear-war-an-urgent-american-problem/

    [12] For analysis of Israel deterring not-yet-nuclear adversaries, see article co-authored by Professor Louis René Beres and (former Israeli Ambassador) Zalman Shoval at the Modern War Institute, West Point (Pentagon): https://mwi.usma.edu/creating-seamless-strategic-deterrent-israel-case-study/

    [13] An obvious case in point would be Iranian regime change to a more dangerous government in Tehran. Here, the “success” of Israel-promoted regime change would be a substantially worse outcome for Jerusalem.

    [14] On Iran’s post-war nuclear weapons potential, see at Israel Defense: https://www.israeldefense.co.il/en/node/65544

    [15] Any future Israeli decisions on preemption would likely be based on (a) expectations of enemy rationality or irrationality; (b) expected likelihood of enemy first-strikes; (c) expected costs of enemy first-strikes; (d) expected schedule of enemy nuclear (or biological) weapons deployments; (e) expected efficiencies of enemy active defenses over time; (f) expected efficiencies of Israel’s active defenses over time; (g) expected efficiencies of Israeli hard-target counterforce operations over time; (h) expected reactions of unaffected regional enemies; and (i) expected US, Russian, Chinese, Pakistani  and/or North Korean reactions to Israeli preemptions.

    Continue Reading

  • Australian scientists advance jadarite processing to fuel clean energy transition-Xinhua

    CANBERRA, July 10 (Xinhua) — Australian scientists are leading research to harness jadarite, a rare mineral originally discovered in Serbia, as a key resource for the transition to clean energy.

    Australian scientists are developing advanced methods to extract and process jadarite’s lithium and boron — key materials for batteries and renewable energy, the Commonwealth Scientific and Industrial Research Organization (CSIRO), Australia’s national science agency, announced Thursday.

    Jadarite, recognized as a new mineral in 2006, is a sodium lithium boron silicate hydroxide with a chemical makeup similar to kryptonite. Unlike the green fictional version, jadarite appears dull white and glows pinkish-orange under UV light, said a CSIRO statement.

    Its real-world significance, however, lies in its rich lithium content, positioning it as a potential game-changer for the global energy sector, it said.

    Australia’s Nuclear Science and Technology Organization (ANSTO) and the Critical Minerals R&D Hub at CSIRO are leading research on processing jadarite and other lithium minerals to advance next-generation batteries and renewable energy, experts said.

    “The Jadar deposit where it was first discovered is considered one of the largest lithium deposits in the world, making it a potential game-changer for the global green energy transition,” said Michael Page, a scientist at ANSTO.

    Continue Reading

  • AI Outperforms Supercomputers in Galaxy Simulation

    AI Outperforms Supercomputers in Galaxy Simulation

    In the first study of its kind, researchers led by Keiya Hirashima at the RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS) in Japan, along with colleagues from the Max Planck Institute for Astrophysics (MPA) and the Flatiron Institute, have used machine learning, a type of artificial intelligence, to dramatically speed up the processing time when simulating galaxy evolution coupled with supernova explosion. This approach could help us understand the origins of our own galaxy, particularly the elements essential for life in the Milky Way.

    Understanding how galaxies form is a central problem for astrophysicists. Although we know that powerful events like supernovae can drive galaxy evolution, we cannot simply look to the night sky and see it happen. Scientists rely on numerical simulations that are based on large amounts of data collected from telescopes and other devices that measure aspects of interstellar space. Simulations must account for gravity and hydrodynamics, as well as other complex aspects of astrophysical thermo-chemistry.

    On top of this, they must have a high temporal resolution, meaning that the time between each 3D snapshot of the evolving galaxy must be small enough so that critical events are not missed. For example, capturing the initial phase of supernova shell expansion requires a timescale of mere hundreds of years, which is 1000 times smaller than typical simulations of interstellar space can achieve. In fact, a typical supercomputer takes 1-2 years to carry out a simulation of a relatively small galaxy at the proper temporal resolution.

    Getting over this timestep bottleneck was the main goal of the new study. By incorporating AI into their data-driven model, the research group was able to match the output of a previously modeled dwarf galaxy but got the result much more quickly. “When we use our AI model, the simulation is about four times faster than a standard numerical simulation,” says Hirashima. “This corresponds to a reduction of several months to half a year’s worth of computation time. Critically, our AI-assisted simulation was able to reproduce the dynamics important for capturing galaxy evolution and matter cycles, including star formation and galaxy outflows.”

    Like most machine learning models, the researchers’ new model is trained using one set of data and then becomes able to predict outcomes based on a new set of data. In this case, the model incorporated a programmed neural network and was trained on 300 simulations of an isolated supernova in a molecular cloud that massed one million of our suns. After training, the model could predict the density, temperature, and 3D velocities of gas 100,000 years after a supernova explosion. Compared with direct numerical simulations such as those performed by supercomputers, the new model yielded similar structures and star formation history but took four times less time to compute.

    According to Hirashima, “our AI-assisted framework will allow high-resolution star-by-star simulations of heavy galaxies, such as the Milky Way, with the goal of predicting the origin of the solar system and the elements essential for the birth of life.”

    Currently, the lab is using the new framework to run a Milky Way-sized galaxy simulation.

    Rate this article

    Thank you!

    Hirashima et al. (2025) ASURA-FDPS-ML: Star-by-star Galaxy Simulations Accelerated by Surrogate Modeling for Supernova Feedback. Astrophys J. doi: 10.3847/1538-4357/add689
    /Public Release. This material from the originating organization/author(s) might be of the point-in-time nature, and edited for clarity, style and length. Mirage.News does not take institutional positions or sides, and all views, positions, and conclusions expressed herein are solely those of the author(s).View in full here.

    Continue Reading

  • Exploring the Manifestation of Non-motor Symptoms in Parkinson’s Disease in a Tertiary Care Center: A Comprehensive Analysis

    Exploring the Manifestation of Non-motor Symptoms in Parkinson’s Disease in a Tertiary Care Center: A Comprehensive Analysis


    Continue Reading

  • Antidepressant Withdrawal Is a Major Public Health Issue, Experts Warn : ScienceAlert

    Antidepressant Withdrawal Is a Major Public Health Issue, Experts Warn : ScienceAlert

    A new review of antidepressant withdrawal effects – written by academics, many of whom have close ties to drug manufacturers – risks underestimating the potential harms to long-term antidepressant users by focusing on short-term, industry-funded studies.

    There is growing recognition that stopping antidepressants – especially after long-term use – can cause severe and sometimes debilitating withdrawal symptoms, and it is now acknowledged by the UK government as a public health issue.

    One of the main reasons this issue took decades to recognise after the release of modern antidepressants onto the market is because medical guidelines, such as those produced by Nice (England’s National Institute for Health and Care Excellence), had for many years declared withdrawal effects to be “brief and mild”.

    This description was based on studies run by drug companies, where people had only taken the medication for eight to 12 weeks. As a result, when patients later showed up with severe, long-lasting symptoms, many doctors didn’t take them seriously because these experiences contradicted what the guidelines led them to expect.

    Related: Some Antidepressants Could Speed Decline in Dementia Patients

    Our recent research helps explain this mismatch. We found a clear link between how long someone takes antidepressants and how likely they are to experience withdrawal symptoms – and how severe these symptoms are.

    We surveyed NHS patients and found that people who had used antidepressants for more than two years were ten times more likely to have withdrawal effects, five times more likely for those effects to be severe, and 18 times more likely for them to be long lasting compared with those who had taken the drugs for six months or less.

    For patients who used antidepressants for less than six months, withdrawal symptoms were mostly mild and brief. Three-quarters reported no or mild symptoms, most of which lasted less than four weeks.

    Withdrawal is milder for those who use antidepressants for less than six months. (fizkes/Getty Images/Canva)

    Only one in four of these patients was unable to stop when they wanted to. However, for long-term users (more than two years), two-thirds reported moderate or severe withdrawal effects, with one-quarter reporting severe withdrawal effects.

    Almost one-third of long-term users reported symptoms that lasted for more than three months. Four-fifths of these patients were unable to stop their antidepressants despite trying.

    About 2 million people on antidepressants in England have been taking them for over five years, according to a BBC investigation. And in the US at least 25 million people have taken antidepressants for more than five years. What happens to people in eight-to-12-week studies is a far cry from what happens to millions of people when they stop.

    Studying what happens to people after just eight to 12 weeks on antidepressants is like testing car safety by crashing a vehicle into a wall at 5km/h – ignoring the fact that real drivers are out on the roads doing 60km/h.

    History repeating itself?

    Against this backdrop, a review has just been published in JAMA Psychiatry. Several of the senior authors declare payments from drug companies.

    In what looks like history repeating itself, the review draws on short-term trials – many funded by the pharmaceutical industry – that were similar to those used to shape early treatment guidelines. The authors conclude that antidepressants do not cause significant withdrawal effects.

    Their main analysis is based on eleven trials that compared withdrawal symptoms in people who had stopped antidepressants with those who had continued them or stopped taking a placebo. Six of these trials had people on antidepressants for eight weeks, four for 12 weeks and just one for 26 weeks.

    They reported a slightly higher number of withdrawal symptoms in people who had stopped antidepressants, which they say does not constitute a “clinically significant” withdrawal syndrome. They also suggest the symptoms could be explained by the “nocebo effect” – where negative expectations cause people to feel worse.

    In our view, the results are likely to greatly underestimate the risk of withdrawal for the millions of people on these drugs for years. The review found no relationship between the duration of use of antidepressants and withdrawal symptoms, but there were too few long-term studies to test this association properly.

    The review probably underestimates, in our view, short-term withdrawal effects too by assuming that the fact that people experience withdrawal-like symptoms when stopping a placebo or continuing an antidepressant cancels out withdrawal effects from antidepressants. But this is not a valid assumption.

    We know that antidepressant withdrawal effects overlap with side-effects and with everyday symptoms, but this does not mean they are the same thing. People stopping a placebo report symptoms such as dizziness and headache, because these are common occurrences.

    However, as was shown in another recent review, symptoms following discontinuation of a placebo tend to be milder than those experienced when stopping antidepressants, which can be intense enough to require emergency care.

    So deducting the rate of symptoms after stopping a placebo or continuing an antidepressant from antidepressant withdrawal symptoms is likely to underestimate the true extent of withdrawal.

    back of an ambulance
    Some withdrawal effects are severe enough to require emergency care. (Mikhail Nilov/Pexels/Canva)

    The review also doesn’t include several well-designed drug company studies that found high rates of withdrawal symptoms. For example, an American study found that more than 60% of people who stopped antidepressants (after eleven months) experienced withdrawal symptoms.

    The authors suggest that depression after stopping antidepressants is probably a return of the original condition, not withdrawal symptoms, because similar rates of depression were seen in people who stopped taking a placebo.

    But this conclusion is based on limited and unreliable data (that is, relying on participants in studies to report such events without prompting, rather than assessing them systematically) from just five studies.

    We hope uncritical reporting of a review based on the sort of short-term studies that led to under-recognition of withdrawal effects in the first place, does not disrupt the growing acceptance of the problem and slow efforts by the health system to help potentially millions of people who may be severely affected.

    The authors and publisher of the new review have been approached for comment.The Conversation

    Mark Horowitz, Visiting Clinical Research Fellow in Psychiatry, UCL and Joanna Moncrieff, Professor of Critical and Social Psychiatry, UCL

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

    Continue Reading