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  • Can Testosterone Protect Women’s Bones After Menopause? Study Reveals Surprising Results

    Can Testosterone Protect Women’s Bones After Menopause? Study Reveals Surprising Results

    It’s sadly no secret that menopause wreaks havoc on your bones and joints. An estimated 20 percent of bone loss can happen during the menopause transition and beyond, dramatically increasing your risk of fractures. And while hormone therapy (HT) with estrogen and progesterone is currently the best defense against bone loss, a recent study published in the Journal of the American Academy of Orthopedic Surgeons suggests that testosterone replacement therapy (TRT) could have some surprising bone-supporting benefits for older women.

    The researchers looked at the Mariner165 Database, which collected info from a million men and women between the ages of 35 to 75 over the course of 11 years. The goal: to see if people taking TRT for at least three months were less likely to have a hip fracture. Why the focus on hip fractures, you ask? They’re a common, expensive, and deadly injury for older adults. (And per the Bone Health and Osteoporosis Foundation, a woman’s risk of breaking a hip is equivalent to her combined risk of breast, uterine, and ovarian cancer.)

    The study authors found that those who were prescribed TRT were nearly two times less likely to get a hip fracture compared to those who were not. This benefit was seen in both men and women, particularly for men over 46 and women over 56.

    Before you go running off to your doctor’s office for a prescription, note that there are some limitations to these findings. We don’t know what types or doses of TRT the researchers were controlling for (just that it’s exogenous, which can include topicals, patches, shots, gels, pills, etc.), and the study was done retroactively, meaning there’s no definite proof of testosterone causing better bone strength. (Plus, TRT as it exists today is not approved by the FDA for women, nor is it typically covered by insurance.)

    But the findings add to the existing—and growing—body of studies that say testosterone could help. “We know from the basic science of testosterone that it can enhance the bone-building effects of estrogen—it plays an additive role,” says Vonda Wright, MD, an orthopedic surgeon and author of Unbreakable. (Wright was not involved with the study.) “But right now, testosterone alone is not a sole modality for building bone.”

    While TRT probably won’t replace HT anytime soon, it could someday offer your skeleton some much-needed backup—and that’s worth further study. The midlife women of the world, now and in the future, deserve more treatment options.

    Headshot of Sofia Lodato

    Sofia Lodato (she/her) is the editorial assistant at Oprah Daily. Aside from reading, writing, and wellness, she is a lover of all things media-related, and can usually be found overanalyzing her latest favorite show, album, or video game.
     

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  • Tokyo Gendai Best Booths 2025

    Tokyo Gendai Best Booths 2025

    This year marks the third edition of Tokyo Gendai. Held in September for the first time, the 2025 fair is organized around three sections: the main Galleries sector; Hana “Flower,” which highlights emerging and mid-career artists; and Eda “Branch,” which features works by established artists and thematic presentations. Sixty-six galleries from 16 or 17 countries and regions are presenting a wide range of work.

    This year also saw an expansion of public programming and increased efforts to support Japan’s art scene and its working artists.

    Among the new initiatives is the inaugural Hana Artist Award, which honors one artist exhibiting in the Hana section and comes with a prize of $10,000. The 2025 recipient is painter Etsuko Nakatsuji (b. 1937), represented by Yoshiaki Inoue Gallery. Another returning initiative, Tsubomi “Flower Bud,” continues its focus on women artists working with craft-based materials such as lacquer, glass, and ceramics. Other highlights include Sato “Meadow,” a group presentation of 12 installations, and a series of artist talks.

    More than a third of the participating galleries this year are newcomers. Magnus Renfrew, global director of organizer Art Assembly, addressed the turnover at a press conference before the fair.

    “There are various reasons for the low number of returning galleries,” he said. “However, we believe that the participation of new galleries is proof that they are gaining a deeper understanding of Japan and leading to new discoveries.”

    Fair director Eri Takane added, “While some galleries found it difficult to participate this year due to the shift from July to September, several first-time galleries that were forced to skip last year due to scheduling conflicts have now joined.”

    What follows is a look at 10 standout presentations from Tokyo Gendai 2025, selected by the ARTnews Japan editorial team.

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  • Study links high THC levels with egg quality and fertility issues

    Study links high THC levels with egg quality and fertility issues

    High levels of THC — the compound in marijuana that causes a “high” — may affect how eggs develop and could lead to fertility problems, miscarriages and chromosome issues in embryos, new research shows.

    The findings were reported Tuesday in the journal Nature Communications.

    Researchers analyzed more than 1,000 samples of ovarian fluid from patients undergoing fertility treatment. They compared unfertilized eggs (oocytes) from 62 women who tested positive for THC with a control group who did not use cannabis.

    The study found that women with detectable levels of THC had a higher egg maturation rate. But they also produced fewer embryos with the correct number of chromosomes.

    “Chromosomes need time to align perfectly to be ready to be fertilized by sperm and create healthy embryos,” Cyntia Duval, who led the study as a postdoctoral fellow at the University of Toronto, told CNN. “So yes, we have more oocytes that are mature, but at what price if they don’t have the right number of chromosomes?”

    The immature eggs were donated by women undergoing fertility treatment and were not suitable for use, Duval said.

    When the eggs were exposed to THC in a lab for 24 hours, researchers found more altered spindles — structural issues that affect chromosomes. These changes can interfere with healthy embryo development.

    However, Duval noted that the study can’t prove cause and effect.

    “This is a hypothesis, and the worst thing I would want is for the public to read this and become fearful,” she told CNN. “More studies are needed to verify our findings and determine how or even if the changes we observed affect reproduction.”

    The findings dovetail with a rise in marijuana use during pregnancy. A June study found that past-month cannabis use among pregnant women more than tripled in the U.S. between 2002 and 2020.

    “The findings of this study are concerning and highlight the importance of a cautious approach in using cannabis when planning to conceive,” Dr. Jamie Lo, an obstetrician and associate professor at Oregon Health & Science University in Portland, told CNN.

    She added in an email that the results could support a harm-reduction strategy.

    “With this information, these patients can consider reducing the amount of cannabis that they are using to mitigate adverse outcomes to their babies,” Lo explained.

    THC potency has quadrupled between 1995 and 2022, with some cannabis concentrates reaching 40% THC or higher, according to the National Institute on Drug Abuse.

    “Higher THC concentrations have been associated with a greater likelihood of cannabis use progressing to cannabis use disorder, among other health concerns,” the Institute’s website says.

    As such, Lo offered a cautionary note.

    “Because it’s hard to know the specific level of THC in various cannabis products on the shelves, I advise my patients to consider safer alternatives to treat the symptoms they’re using cannabis for or at least try to reduce the frequency of their use,” Lo said.

    More information

    The American Academy of Family Physicians has more on cannabis use during pregnancy.

    Copyright © 2025 HealthDay. All rights reserved.

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  • Andre Onana: Manchester United keeper joins Trabzonspor on loan

    Andre Onana: Manchester United keeper joins Trabzonspor on loan

    Manchester United keeper Andre Onana has joined Trabzonspor on loan for the rest of the 2025-26 season.

    The move has taken place before the transfer window in Turkey closes on Friday and follows the Cameroon international not playing in United’s opening three Premier League games.

    “We would like to wish Andre good luck,” said United in announcing the deal, which is subject to international clearance and registration.

    Onana’s only appearance for Ruben Amorim’s side this season came in their shock Carabao Cup exit at the hands of League Two Grimsby.

    The 29-year-old was signed from Inter Milan for £47.2m in July 2023 by former Old Trafford boss Erik ten Hag to replace David de Gea as United’s number one.

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  • Jair Bolsonaro’s coup trial gripped Brazil

    Jair Bolsonaro’s coup trial gripped Brazil

    This is a huge moment for Brazil.

    Ex-President Jair Bolsonaro has been convicted of attempting a coup and leading an armed criminal group after losing the last election, which culminated in his supporters attacking government buildings.

    He now faces a 27-year prison sentence, after four out of five of Brazil’s Supreme Court justices found him guilty.

    For years, Bolsonaro has fiercely divided the country into those who love him and those who hate him.

    His supporters, who include President Donald Trump, have described the trial as political persecution. Trump used it as an excuse to impose 50% tariffs on Brazil.

    Trump has said he is “very unhappy” with the verdict and Secretary of State Marco Rubio said the US would “respond accordingly to this witch hunt”. Bolsonaro’s son Eduardo, who has been lobbying in the US on his father’s behalf, said he expects the US to impose more sanctions. The US had already sanctioned the Supreme Court judge Alexandre de Moraes.

    His critics have praised the proceedings as necessary to bring closure, and to set a precedent that trying to undermine democracy will not be tolerated.

    This ruling is likely to divide the country further.

    This trial has gripped Brazil, as millions have seen it live-streamed on social media and television into their homes. And the story line has been no less dramatic than a TV series.

    Many people may remember the shocking moments when thousands of Bolsonaro supporters attacked government buildings on 8 January 2023, in scenes reminiscent of the 6 January Capitol riots in the US two years before.

    But throughout the course of this trial, many gobsmacking pieces of evidence have been revealed and read out in court.

    These include that a plan, drafted by Bolsonaro’s allies, for elite armed forces personnel to assassinate the president-elect Luiz Inacio “Lula” da Silva, his running mate, and the Supreme Court judge Alexandre de Moraes was printed out at the presidential palace. It listed “poison” as a method to kill Lula.

    Bolsonaro’s lawyer was visibly incensed on behalf of his client, when he argued there was no evidence linking Bolsonaro to this plot or the 8 January riots.

    The court was also reminded of Bolsonaro’s attempts to cast doubt on the electoral system. These included him holding a meeting with foreign ambassadors at the presidential palace to make false claims about electronic voting machines before the election, and public bodies obstructing voters from getting to polling stations – under the guise of “checking the condition of vehicles” – on the day of the vote.

    At various moments throughout this trial, the judges referred to Brazil’s past. Its democracy is young – it was only restored in 1985 after two decades of a dictatorship, instigated by a military coup, backed by the US.

    To Bolsonaro’s critics, the parallels were chilling.

    The judge leading this case – Alexandre de Moraes – said Brazil risked “slowly forgetting” that it nearly returned to a dictatorship because “a criminal organisation, comprised of a political group, doesn’t know how to lose elections”.

    Brazil’s past has been littered with coups or attempted coups, but no one has ever sat in the dock, and past plotters have been granted amnesty. Bolsonaro’s critics hope this verdict sends a clear signal: no more.

    So what happens next?

    Bolsonaro’s sentence is, effectively, a life one for the 70-year-old.

    The judges said at least 24 years and 9 months of this should be spent in jail.

    He will likely try to appeal the sentence length and ask for it to be turned into a house arrest – something he is already on.

    Jair Bolsonaro didn’t appear in the courtroom for the verdicts. His lawyer has cited health reasons. He has suffered various health problems after he was stabbed at a presidential campaign rally in 2018, before he took office.

    There is a precedent in Brazil of convicts being granted house arrest due to age or health reasons.

    Congress – where Bolsonaro’s party has a majority – is also trying to push through legislation that would grant him amnesty. One of the right-wing frontrunners for next year’s presidential election, who is courting Bolsonaro’s support, has said he would give Bolsonaro amnesty if elected.

    So, while this ruling is an important milestone, his punishment still remains unclear.

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  • COVID-19 no longer among the top 10 causes of death in the U.S.

    COVID-19 no longer among the top 10 causes of death in the U.S.

    For the first time since the pandemic began, COVID-19 dropped out of the nation’s top 10 causes of death in 2024, new U.S. government data shows.

    Overall U.S. death rates also fell to their lowest level since 2020, according to the National Center for Health Statistics.

    Heart disease and cancer remained the leading causes of death. In all, 683,037 deaths due to heart disease and 619,812 due to cancer were reported last year — both up slightly from 2023.

    Unintentional injuries ranked third, while suicide moved into the top 10 for the first time, displacing COVID-19.

    “Heart disease is still number one, and it’s definitely not going in the right direction,” Dr. Eric Topol, founder and director of Scripps Research in San Diego, told STAT News.

    Further, “there are many thousands of people dying of COVID still,” he added.

    After unintentional injuries, the list continued with stroke, chronic lower respiratory diseases, Alzheimer’s disease, diabetes, kidney disease, chronic liver disease and cirrhosis.

    Topol said these leading causes are largely preventable through lifestyle changes such as exercise and diet.

    “These numbers are not encouraging,” he told STAT News. “We’re talking about diseases that are eminently preventable, just with lifestyle factors, but we have 75% of the population that doesn’t do even the minimum requirement of exercise.”

    Despite the overall drop in death rates, some disparities remain:

    Black Americans continue to have the highest death rates among racial and ethnic groups.

    Men face significantly higher death rates than women: 844.8 deaths per 100,000 compared with 613.5 per 100,000 for women.

    Topol added that U.S. health outcomes still lag behind many other countries, pointing to gaps in chronic disease prevention, life expectancy and maternal and infant death rates.

    He expressed dismay about cuts in federal funding for health-related studies.

    “The reduction of research support isn’t going to help matters,” he said. “It’s the U.S. Centers for Disease Control and Prevention. Where is the prevention?”

    More information

    The U.S. Centers for Disease Control and Prevention has more on the leading causes of death in the U.S.

    Copyright © 2025 HealthDay. All rights reserved.

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  • Study Shows How Smoking Drives Pancreatic Cancer: What to Know

    Study Shows How Smoking Drives Pancreatic Cancer: What to Know

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    Chemicals in cigarette smoke may promote the growth and spread of tumors in pancreatic cancer, a new mouse study shows. Bob Thomas/Getty Images
    • Prior research has linked smoking to pancreatic cancer, but the reasons why were unclear.
    • A new mouse study shows that chemicals in cigarette smoke change the immune system, which may prevent the immune system from fighting tumors.
    • These findings could open the door for new treatments targeting this mechanism, but in the meantime, experts say this is yet another reason to quit smoking.

    It has long been understood that there was a link between smoking and pancreatic cancer, but the exact mechanism was unclear.

    Now, a group of scientists has discovered that certain chemicals in cigarette smoke actually reprogram the immune system in a way that helps tumors grow and spread. This could point to new treatment strategies for pancreatic cancer, which currently has very few options.

    According to the authors, their findings are significant because pancreatic cancer is one of the deadliest types of cancer, with only a five-year survival rate of 13%. The full results of the study were published on September 4 in Cancer Discovery.

    In 2025 alone, it is estimated that more than 67,000 Americans will be diagnosed with pancreatic cancer, and nearly 52,000 will die from it.

    The research, carried out by a team at the University of Michigan, combined lab experiments, mouse models, and human tissue samples.

    They focused on a group of chemicals in cigarette smoke called aryl hydrocarbon receptor ligands (AhRLs).

    These include well-known carcinogens such as dioxins. To mimic smoking, mice were treated with cigarette smoke extract or with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a powerful AhR ligand.

    The researchers then implanted pancreatic cancer cells directly into the animals’ pancreases to track tumor growth.

    They also used genetically engineered mice to tease apart how different immune cells responded to these smoke-related chemicals.

    Finally, they compared the mouse findings to human pancreas tissue from organ donors and cancer patients.

    The results were striking. Both cigarette smoke and TCDD accelerated pancreatic tumor growth in mice — but only if their immune system was intact. That means the chemicals weren’t damaging tumor cells directly. Instead, they were altering the immune response.

    The key player was a receptor called AhR on CD4+ T cells. Once activated, these cells began producing more of a molecule called IL-22 and also boosted the number of regulatory T cells (Tregs).

    Normally, Tregs keep the immune system in check. But in this case, they prevented CD8+ T cells — the ones that usually attack cancer — from doing their job. In other words, smoking tipped the balance of the immune system away from fighting tumors and toward letting them grow.

    The team also saw that exposure to TCDD promoted early precancerous changes in the pancreas, suggesting that chemicals in cigarette smoke may play a role not just in cancer progression but also in its initiation.

    Human tissue samples told a similar story. Smokers had more activation of the AhR pathway, and pancreatic tumors from smoking patients contained more Tregs.

    The number of these suppressive cells also tracked with how much the patient had smoked over their lifetime.

    According to the authors, what they have learned could potentially lead to new treatments that block AhR activation or reduce the suppressive effect of Tregs.

    This could help the immune system mount a stronger anti-cancer response, especially in smokers.

    They additionally note that, since AhR ligands are also found in pollutants and industrial chemicals, the findings may carry wider public health significance.

    However, Asfar Azmi, PhD, director of the Pancreatic Cancer Research Initiative at the Barbara Ann Karmanos Cancer Institute, who was not involved in the study, urges caution in interpreting what the findings mean.

    “Although this research represents an important step forward, it’s still early,” Azmi said, adding that much of the evidence comes from labs, animal studies, and findings from human tissues.

    “That means the results show a mechanism linking smoking and pancreatic cancer, but they don’t prove that every smoker will develop this cancer, or that blocking this pathway will automatically prevent it,” he told Healthline.

    Azmi noted that more clinical research is necessary before these findings will actually change doctors’ practices regarding the treatment of pancreatic cancer.

    Najeeb Al Hallak, MD, MS, a medical oncologist with the Barbara Ann Karmanos Cancer Institute, said that “the message is clear that quitting smoking is one of the most important steps people can take to lower their risk of pancreatic cancer.” Hallak wasn’t involved in the study.

    He further pointed out that smoking cessation may help reduce people’s risk of many other cancers, as well as heart and lung diseases.

    “Even reducing exposure helps,” Hallak told Healthline, “but the greatest benefit comes from complete cessation.”

    Hallak added that if you are a heavy smoker, it would also be a good idea to speak with your doctor about pancreatic cancer risk and whether you qualify for specialized monitoring or risk-reduction programs.

    He also acknowledged the difficulties of smoking cessation, offering smokers some encouraging words. “Quitting is hard, but it is absolutely possible, and thousands succeed every day,” he said.

    The first step in quitting? Speak with your personal physician. “They can guide you to nicotine replacement (patches, gum, or lozenges) or medications that reduce cravings,” Hallak said.

    Hallak added that seeking support is essential. “Counseling, support groups, and quit lines (e.g., 1-800-QUIT-NOW) double your chances of success,” he said.

    Additionally, Hallak suggests planning for your triggers. For example, if you are accustomed to smoking after meals or with coffee, create a healthier alternative that you can do instead.

    Finally, he urges that you don’t give up after slips.

    “Many people need several tries before quitting for good,” said Hallak. “Each attempt builds skills for the next.”

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  • Powering Up: Improving Energy Grid Reliability and Resilience to Lower Energy Bills | Briefing

    Powering Up: Improving Energy Grid Reliability and Resilience to Lower Energy Bills | Briefing

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    A live webcast will be streamed at www.eesi.org/livecast.

    The Environmental and Energy Study Institute (EESI) invites you to a briefing about policy solutions to meet the reliability, resilience, and affordability challenges facing the U.S. energy grid. The grid underpins modern life—enabling economic activity, supporting national security, and powering everything from basic necessities in homes to critical infrastructure like hospitals and transportation. Today, the grid’s stability is being tested like never before. Aging infrastructure, extreme weather, and unprecedented increases in electricity demand could soon overwhelm generation and transmission capacity and outpace states and utility planners. These challenges hit home, from higher energy bills for consumers to rolling blackouts that leave communities vulnerable during heat waves, wildfires, winter storms, and hurricanes. 

    This briefing will outline policy options and technological innovations to address these challenges. Panelists will expand on several aspects of grid modernization, including the buildout of new transmission lines, bringing online new power generation and energy storage capacity, and improving energy efficiency. They will also describe the state of permitting reform in the 119th Congress. Attendees will leave this briefing with a better understanding of the imperatives and multiple benefits of an environmentally and economically sustainable energy grid to power the 21st century.

    Panelists to be announced. 
     

    This event is free and open to the public. Please RSVP to expedite check-in.

     

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  • Gertrude Stein got famous lampooning celebrity culture – but not everyone got the joke

    Gertrude Stein got famous lampooning celebrity culture – but not everyone got the joke

    Today, modernist literary icon Gertrude Stein is famous for many reasons. The “autobiography” she wrote of her partner Alice B. Toklas: a gossipy, ironic tour of bohemian Paris, featuring memorable cameos by artist Henri Matisse, poet T.S. Eliot, Ernest Hemingway and others. Surviving Nazi-occupied France as a Jewish lesbian, somehow. And of course, her dazzling, disorienting and difficult body of work. Often in that order.

    Francesca Wade’s ambitious new biography Gertrude Stein: An Afterlife charts how her subject sought and achieved lasting fame – but not exactly on her own terms.

    “Work your ass off to change the language and don’t ever get famous,” experimental American poet Bernadette Mayer – who was influenced by Stein – told her students. Stein did, undeniably, challenge the way we think about language – as well as about meaning and literary form.

    Wade’s nuanced biography is divided into two distinct parts. The first is a rich, detailed account of Stein’s life and career. The second picks up in the immediate aftermath of Stein’s death in 1946. Shifting registers, it charts the complicated and contested legacy she left behind.

    Wade traces Stein’s posthumous reputation through currents in criticism, showing how her work has been variously celebrated or sidelined, depending on prevailing ideological and educational trends.

    The result is a book as much about Stein’s lasting presence in our culture as it is about the life she lived.

    From Pennsylvania to Paris

    Born in Allegheny, Pennsylvania, in 1874, Stein studied psychology at Radcliffe College under the tutelage of William James, conducting research into processes of attention and the workings of the human mind. Her true intellectual and artistic journey, however, began when she moved to Paris in 1903.

    Stein immersed herself in the city’s bustling modern art scene and hosted salons in her apartment at 27 rue de Fleurus on the Left Bank. From there, she honed a pioneering approach to writing that came to define her creative practice.

    The move marked a decisive break with the conventions of 19th-century realism and the emergence of a singular literary voice – rhythmic, irreverent, recursive and pretty much unlike anything else out there. Inspired by the formal innovations of Cubism and particularly by her close friendship with Pablo Picasso, who painted a famous portrait of her, Stein strove to translate visual abstraction into words.

    Her most famous works included Tender Buttons (1914) and The Making of Americans (1925). Playful and provocative in equal doses, her prose takes no prisoners.

    Just as Cubist painters distorted perspective to reveal multiple viewpoints at once, Stein dismantled conventional syntax and structure, aiming not to describe experience, but to enact it on the printed page.

    Here, for example, is Stein’s description of what she assures us is meant to be a piano, taken from Tender Buttons:

    If the speed is open, if the color is careless, if the selection of a strong scent is not awkward, if the button holder is held by all the waving color and there is no color, not any color. If there is no dirt in a pin and there can be none scarcely, if there is not then the place is the same as up standing.

    As Wade notes, Stein’s uncompromising writing, replete as it is with “wordplay, non-sequitur and extended passages of repetition, confounded publishers, critics and readers”. Bafflement soon became suspicion.

    Was Stein a genius, revolutionising a sterile literary tradition, or a self-important charlatan? A true experimenter who freed language from its formal constraints, or a pretender who knew nothing about the modern art she supposedly championed?

    A gossipy tour of bohemian Paris

    This, in part, helps to explain why, at the age of 58, Stein sat down to write The Autobiography of Alice B. Toklas – the volume that would secure her lasting fame and fortune, even as it threatened to overshadow the more radical type of writing she spent decades perfecting.

    Proud as she rightly was of her achievements, Stein had nonetheless struggled to persuade publishers to take her work seriously. Yet, as literary scholar Kristin Grogan observes, Stein always maintained her work “could be read by a general audience”. Faced with this impasse, she decided it was now or never.

    Appearing in 1933, the Autobiography was a calculated departure from Stein’s earlier work. Accessible and ironic, the book is narrated from the perspective of Stein’s life partner, California-born Alice B. Toklas. Taken at face value, it offers readers a free-wheeling tour of bohemian Paris and its celebrities.

    Yet there is far more to it than initially meets the eye: the text is a masterclass in ventriloquism, a memoir disguised as autobiographical reportage, in which Stein carefully constructs her own legend while seeming to stand aside. By writing in her lover’s voice, she found a way to narrate – and carefully curate – her own story without seeming to; the result is at once self-effacing and self-aggrandising, intimate and performative.

    In Wade’s words, the book

    is a joke, a myth, an audacious act of knowing artifice. It contravenes every rule of autobiography – and, in doing so, draws attention to its own act of creation.

    Stein may have upended the rules yet again, but the general public couldn’t get enough. “For the first time in her career,” Wade reflects,

    her writing was in demand – but the voice readers wanted was not her own. She had finally achieved the fame she had long desired, but for the wrong reasons: she was being appreciated not as a serious writer, but as the comedic heroine of Alice B. Toklas’ fictional autobiography.

    Stein took tea with Eleanor Roosevelt on an American book tour.
    AAp

    Riding the wave of the book’s runaway success, Stein returned to America for the first time in 30 years. Arriving in October 1934, she spent six months touring the country, delivering lectures and appearing before enthusiastic crowds. Feted as a bona fide celebrity, she took tea with Eleanor Roosevelt, paid a visit to F. Scott Fitzgerald and discussed cinema with Charlie Chaplin.

    Though she relished the attention, her newfound fame left her in something of a quandary. As Wade writes, the Autobiography “had been marketed as a tell-all confessional affording privileged access to a coterie of celebrities”. The subtlety of Stein’s venture was lost on many:

    At no point were readers informed that the Autobiography was written with cunning self-awareness and a large dose of irony: that it lampoons the very celebrity culture to which Stein had now fallen prey, which reduces artists to cartoonish, two-dimensional figures, and privileges the personality over the work.

    Stein worried: “By writing as Alice B. Toklas, had she killed off Gertrude Stein?”

    The American tour was followed by a prolonged period of self-reflection, where she mused about what her writing – and the practice of writing itself – meant.

    Vichy France and Nazi pressure

    Back in France, Stein spent the latter half of the 1930s producing a series of introspective, highly experimental works, “as she wrestled with her competing desires for solitude and for appreciation”. Then, in 1939, “her peaceful routines” were ruptured, as war loomed.

    The outside world began to press in on the cherished domestic life Stein and Toklas had so carefully constructed. As the threat of Nazi Germany’s invasion of France came into sharper focus, she became fixated on astrological predictions and prophetic signs, retreating into bouts of wishful thinking.

    But when Hitler invaded France in May 1940, illusion gave way to reality. French flags were replaced with Nazi swastikas. Clocks were set to Berlin time. Antisemitic flyers appeared on lampposts. Soldiers roamed the streets.

    Out shopping in the commune of Belley, Stein and Toklas, who had for many years rented a house in the nearby hamlet of Bilignin, watched tanks rumble into the market square. A bridge was bombed. Curfews were imposed. Nightly blackouts became commonplace.

    Despite the severity of the situation, Stein continued to cast about for sources of optimism. Like many others in France, she took solace in the figure of Philippe Pétain, who appeared to offer stability amid the chaos and uncertainty.

    Hurriedly installed as the premier of France in the wake of the Nazi invasion, the 84-year-old former solider signed the Franco-German Armistice on June 22, 1940. With this act, France was split in two: the north was occupied by the Germans, while the south – soon known as Vichy France – remained nominally independent under Pétain’s rule.

    Philippe Pétain was the leader of Nazi-occupied Vichy France, which introduced its own antisemitic legislation.
    AAP

    The Vichy regime, far from being a passive puppet of the Third Reich, swiftly introduced its own antisemitic legislation – stripping Jews of citizenship, banning them from public service and facilitating deportations even before Nazi pressure demanded it.

    Jewish lesbians surviving

    Despite having the option to go back to the US, Stein and Toklas – now living under the Vichy regime – chose to stay in France. Their decision to stay, and the question of how they managed to survive the war unscathed, has long preoccupied critics and biographers alike. Janet Malcolm, for one, famously asked: “How had the pair of elderly Jewish lesbians survived the Nazis?”

    It’s a question that continues to haunt Stein’s legacy. Published in 2007, Malcolm’s Two Lives is one of two major works Wade considers in detail when addressing this murky chapter of Stein’s life. The other is literary historian Barbara Will’s Unlikely Collaboration, which centres on Stein’s decades-long friendship with Bernard Faÿ, who would go on to become a powerful operator in the Vichy regime.

    A historian of Franco-American relations, Faÿ, who helped organise Stein’s triumphant tour of America, played a prominent role in the regime’s anti-Masonic efforts – a sweeping crackdown that involved shuttering Masonic lodges, publishing lists of members and accusing Freemasons of anti-French conspiracies.

    He was eventually convicted for his collaborationist activities and sentenced to prison, but escaped in September 1951. Wade details how, in a bizarre, almost unbelievable twist worthy of the detective novels Stein once devoured, it was none other than Alice B. Toklas who stumped up the funds that helped him cross into Switzerland, disguised as a Catholic priest.

    How had the pair of elderly Jewish lesbians survived the Nazis?
    Bettmann/Getty

    Will is interested in not just what Stein may have done to protect herself during the war, but what that might mean when we read her work – and what we expect from our greatest writers.

    She draws particular attention to the fact Stein translated dozens of politically reactionary and nationalistic speeches by Pétain, intended for publication in America. In the preface to her translation, Stein compared Pétain with George Washington as “first in war, first in peace and first in the hearts of countrymen.”

    While these translations remain unpublished, Will argues – convincingly – that they reveal Stein as a willing propagandist for the Vichy regime. Her rigorously researched academic study raises uncomfortable questions about ethics, moral compromise and the troubling link between modern art and reactionary politics.

    Needless to say, Unlikely Collaborations ignited a firestorm of controversy when it hit shelves in 2011. Some accused Will of tarnishing Stein’s name; others praised her for confronting aspects of Stein’s biography that had long been downplayed or simply ignored.

    A reappraisal: art and politics

    Wade revisits this scandal in the final chapter of Gertrude Stein: An Afterlife. Not to offer definitive judgement, but to reflect on some tensions that continue to shape how we understand Stein: as a writer and a person. Wade reminds us

    Stein has always made people uncomfortable. Her detractors have consistently focused on her friendships, her looks, clichéd ideas of her style; anything but her writing. Her excesses – linguistic and bodily – have been seen as suspect, “ominous”, as though she must have something to hide.

    She continues:

    Discussions of artists with unsavoury politics or personal histories tend to hinge on how and whether art can be divorced from its maker, how enjoyment of a work can or should change if its creator is disgraced. But Stein’s work is usually considered dispensable in these conversations: derided, caricatured, flattened, as if it’s a relief to have a concrete reason to dismiss her.

    It is to Wade’s utmost credit that she refuses this dismissal. She insists both Stein’s life and work “have far more to offer curious readers than these reductive approaches allow”.

    By squarely acknowledging Stein’s very real personal shortcomings, while affirming the enduring vitality of her writing – dazzling, disorienting and difficult as it undoubtedly is – Wade’s biography makes a persuasive case for why Stein’s work continues to matter, “as new voices come into dialogue with it, drawing out different meanings and possibilities”.

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  • FTC launches inquiry into AI chatbots acting as companions, their effects on children

    FTC launches inquiry into AI chatbots acting as companions, their effects on children

    The Federal Trade Commission has launched an inquiry into several social media and artificial intelligence companies about the potential harms to children and teenagers who use their AI chatbots as companions.

    The FTC said Thursday it has sent letters to Google parent Alphabet, Facebook and Instagram parent Meta Platforms, Snap, Character Technologies, ChatGPT maker OpenAI and xAI.

    The FTC said it wants to understand what steps, if any, companies have taken to evaluate the safety of their chatbots when acting as companions, to limit the products’ use by and potential negative effects on children and teens, and to apprise users and parents of the risks associated with the chatbots.

    EDITOR’S NOTE — This story includes discussion of suicide. If you or someone you know needs help, the national suicide and crisis lifeline in the U.S. is available by calling or texting 988.

    The move comes as a growing number of kids use AI chatbots for everything — from homework help to personal advice, emotional support and everyday decision-making. That’s despite research on the harms of chatbots, which have been shown to give kids dangerous advice about topics such as drugs, alcohol and eating disorders. The mother of a teenage boy in Florida who killed himself after developing what she described as an emotionally and sexually abusive relationship with a chatbot has filed a wrongful death lawsuit against Character.AI. And the parents of 16-year-old Adam Raine recently sued OpenAI and its CEO Sam Altman, alleging that ChatGPT coached the California boy in planning and taking his own life earlier this year.

    Character.AI said it is looking forward to “collaborating with the FTC on this inquiry and providing insight on the consumer AI industry and the space’s rapidly evolving technology.”

    “We have invested a tremendous amount of resources in Trust and Safety, especially for a startup. In the past year we’ve rolled out many substantive safety features, including an entirely new under-18 experience and a Parental Insights feature,” the company said. “We have prominent disclaimers in every chat to remind users that a Character is not a real person and that everything a Character says should be treated as fiction.”

    Meta declined to comment on the inquiry and Alphabet, Snap, OpenAI and X.AI did not immediately respond to messages for comment.

    OpenAI and Meta earlier this month announced changes to how their chatbots respond to teenagers asking questions about suicide or showing signs of mental and emotional distress. OpenAI said it is rolling out new controls enabling parents to link their accounts to their teen’s account.

    Parents can choose which features to disable and “receive notifications when the system detects their teen is in a moment of acute distress,” according to a company blog post that says the changes will go into effect this fall.

    Regardless of a user’s age, the company says its chatbots will attempt to redirect the most distressing conversations to more capable AI models that can provide a better response.

    Meta also said it is now blocking its chatbots from talking with teens about self-harm, suicide, disordered eating and inappropriate romantic conversations, and instead directs them to expert resources. Meta already offers parental controls on teen accounts.

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