- Intel gets $2 billion lifeline in the form of SoftBank equity investment Reuters
- Intel shares jump as Softbank to buy $2bn stake in chip giant BBC
- SoftBank Group and Intel (INTC.O) Sign $2 Billion Investment Agreement Bitget
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Intel gets $2 billion lifeline in the form of SoftBank equity investment – Reuters
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Intel’s stock rallies after $2 billion investment by Japan’s SoftBank
By Mike Murphy
Intel headquarters in Santa Clara, Calif.
Intel Corp. shares jumped in after-hours trading Monday after the chipmaker announced a $2 billion investment by Japan’s SoftBank Group Corp.
Earlier in the day, Bloomberg News had reported the Trump administration was in talks to take a 10% stake in Intel, essentially equal to the amount of funding the company received from the Chips and Science Act under the Biden administration. That sent the stock down 3.7% in regular trading.
But shares turned around in the extended session after the SoftBank announcement, rallying 5.4%.
In a statement late Monday, Intel (INTC) said the deal with SoftBank (JP:9984) comes as both companies “deepen their commitment to investing in advanced technology and semiconductor innovation” in the U.S.
“Semiconductors are the foundation of every industry,” SoftBank Chief Executive and Chairman Masayoshi Son said in a statement. “For more than 50 years, Intel has been a trusted leader in innovation. This strategic investment reflects our belief that advanced semiconductor manufacturing and supply will further expand in the United States, with Intel playing a critical role.”
SoftBank shares fell 1.8% in Tokyo trading.
Intel has been undergoing a painful restructuring as it tries to catch up in the AI chip game, after being surpassed by rivals such Taiwan Semiconductor Manufacturing Corp. (TSM). Intel reported another quarterly loss last month, and President Donald Trump recently called for CEO Lip-Bu Tan’s resignation, though Trump toned down his rhetoric following a meeting with Tan last week.
Read more: Trump’s clash with Intel’s CEO isn’t just politics – it’s a crucial test for U.S. chip making
In a statement Monday, Tan said he was “pleased” with SoftBank’s investment, “and I appreciate the confidence [Son] has placed in Intel.”
SoftBank will pay $23 per share of Intel common stock.
Intel shares closed Monday at $23.66 a share, and are up about 18% year to date, compared to the S&P 500’s SPX nearly 10% gain.
Also read: Opinion: Intel has 18 months to determine its future – or Qualcomm and Arm will
-Mike Murphy
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Nepal eliminates rubella, highly contagious viral disease: WHO
August 19, 2025
KATHMANDU – Nepal has eliminated rubella, a highly contagious viral disease as a public health problem, the World Health Organisation, announced on Monday.
The UN health body in its statement said that it is a remarkable achievement for a country making concerted efforts to protect its people from vaccine preventable diseases.
Rubella, or German measles, is a highly contagious viral infection. It is serious particularly for pregnant women as infection can lead to miscarriage, stillbirth, or a range of lifelong and debilitating birth defects. But rubella is preventable with safe and cost-effective vaccines.
“Nepal’s success reflects the unwavering commitment of its leadership, persistent efforts of the health care workers and volunteers, and unstinting support of engaged and informed communities, for a healthy start for babies and a future free of rubella disease,” said Dr Catharina Boehme, officer-in-charge WHO South-East Asia, while endorsing the recommendation of the Regional Verification Commission for Measles and Rubella elimination in South-East Asia Region (SEA-RVC) for Nepal to be verified for eliminating rubella.
The SEA-RVC which held its annual meeting from July 22-24, 2025, reviewed and evaluated information and data submitted by the national verification committee on measles and rubella disease surveillance and immunisation coverage rates, and recommended verification of rubella elimination in Nepal.
Nepal is the sixth country in WHO South-East Asia to achieve rubella elimination. Prioritising elimination of measles and rubella as public health problems in WHO South-East Asia by 2026, Bhutan, DPR Korea, Maldives, and Timor-Leste have eliminated measles, and Bhutan, DPR Korea, Maldives, Sri Lanka, Timor- Leste, and now Nepal have eliminated rubella.
“Congratulations to Nepal for eliminating rubella. This public health achievement is the result of close collaboration between the government, dedicated health workers, partners and communities,” said Dr Rajesh Sambhajirao Pandav, WHO Representative to Nepal. “WHO is proud to have contributed to this journey and remains committed to supporting Nepal sustain this accomplishment.”
Nepal introduced rubella-containing vaccine in its immunisation programme in 2012 with a nationwide campaign for the age group 9 months to 15 years. A second dose of rubella-containing vaccine was added to the routine immunisation schedule in 2016.
Four national campaigns with rubella vaccines in 2012, 2016, 2020, and 2024, helped increase access, despite major public health emergencies such as the COVID-19 pandemic and earthquakes in 2015 and 2023. By 2024, Nepal achieved over 95 percent coverage for at least one dose of rubella vaccine.
Innovative strategies such as observing ‘immunisation month’, outreach to vaccinate missed children, and motivation for the districts to be declared ‘fully immunised’, provided further impetus to elimination efforts.
To further strengthen surveillance, Nepal recently introduced a robust laboratory testing algorithm, the first in the WHO South-East Asia Region to do so.
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Sana gets Senate ticket – Newspaper
LAHORE: PML-N President Nawaz Sharif has awarded the party ticket to PM’s adviser Rana Sanaullah for the Senate by-election from Punjab for a general seat.
The seat was vacated due to PTI’s Senator Ejaz Chaudhry’s disqualification by the Election Commission after his conviction in May 9, 2023, cases. The election will be held on September 9.
Published in Dawn, August 19th, 2025
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Singapore Dollar Consolidates Amid Focus on Possible Russia-Ukraine Meeting – The Wall Street Journal
- Singapore Dollar Consolidates Amid Focus on Possible Russia-Ukraine Meeting The Wall Street Journal
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PM reaffirms Pakistan's commitment to serving humanity – RADIO PAKISTAN
- PM reaffirms Pakistan’s commitment to serving humanity RADIO PAKISTAN
- Dar urges global solidarity to address rising humanitarian crises Associated Press of Pakistan
- Humanity transcends all boundaries, relationships: CM Maryam Dunya News
- PM reiterates Pakistan’s commitment to serving humanity on World Humanitarian Day Dunya News
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Normal abnormal – Newspaper – DAWN.COM
THE humidity hangs heavily in the air but doesn’t deter the quiet protest by a small group of women. They sit silently, their heads bowed, a small splash of colour against the grey concrete. With their old-fashioned hand fans, they occupy a sheet of plastic in the middle of the road.
The nearby green areas, which once allowed Pakistan to bring its problems to Islamabad by holding protests there, is closed to these women. The earth and grass are far too comfortable for them to be allowed there. They have to sit on the road, close to a busy commercial area, but away from the business in the area, as traffic barriers create a boundary, separating them from life in the capital. They have been here for a month but have not managed to disturb the life of the city or the government. How can they when even the doors of the washrooms of the press club close by are closed to them? Those who should be the flag-bearers of freedom of information are now a part of a system which bears down on citizens rather than standing up for the oppressed.
So it’s not just the washrooms but also coverage which is denied. These protesters are ignored, blacked out. There was a time, when such a gathering would have galvanised enough opinion to put any government on the back foot. Not anymore. The women’s steadfastness in this heat and in these circumstances moves no one. Perhaps partly because most people do not even know they are here and partly because this government has no space to even pretend to care about human rights.
The protest has been rendered invisible.
But then the political suffering of women has been normalised in the abnormal times we live in — the women in Islamabad who are not even allowed to sit on grass lest it prove too comfortable, or Mahrang Baloch who has been imprisoned with little chance of any relief in the near future. In Lahore, Yasmin Rashid has been behind bars for two years, with little concern for anyone outside of her party (which can barely do more than pay lip service to the matter). Her age moves no one; neither do the elderly women sitting on the road in this heat in a corner of Islamabad, carrying pictures of their missing loved ones in their heavily wrinkled hands. Their endless wait is for closure as well as some compassion from those in charge.
Ask the government about anything untoward and they simply shrug it off.
But suffering and lack of compassion have been normalised in the abnormal times we live in. As has been the indifference of political parties, which can no longer even pretend to care. Not even those who continue to bask in the glory of a woman who was once the lone symbol of suffering and the target of the powerful ones.
This is not all that has been normalised.
Consider journalism. Arrests, FIRs, disappearances — temporary and permanent — were part of what journalists signed up for. What it meant was that only the brave ones would continue down certain paths (most opened the door and walked through to the compound where awards adorn one’s resumé). But despite this, we have seen a fair share of brave souls who continued to face the dangers. Here too, though, there is an effort to remind them that this may not prove enough.
In recent times, at least two journalists have spoken about how the bank accounts of family and even acquaintances have been blocked. Parents, siblings and even vendors who made the mistake of selling to pesky journalists have been affected. The only recourse left to them were the courts, which, too, are now enveloping themselves in the mantle of indifference. But the message is that collective punishment is the fate of those who will not heed more specific messages about falling in line. Or that the element of surprise will always be their fate. When blocked bank accounts did not prove enough, one of them was stopped from flying out of the country recently. Since then, a PTI politician’s daughter has also found her way to the list. Her father is neither in power nor in parliament and is perhaps not in a position to make any decision but still had to be sent a message. And for this, a university student was stopped from leaving the country, putting her education at risk.
In all of these random, seemingly disconnected incidents, there is a commonality — no one can be asked about them or even shamed. The government has moved beyond this — ask them about anything untoward and they simply shrug it off. There must be a reason, a valid reason, is the only answer. If it’s a journalist, he or she must have done something wrong to attract the ‘long arm of the law’. And if there is a story involving a politician from the opposition, the easiest response is to either hint at the former’s non-patriotic credentials or feign ignorance and move on.
Indifference has been normalised in these abnormal times.
And while some of us do express horror, grief and shock, it amounts to little; the second such incident is taken in its stride. It has already happened to others and if the previous incident was accepted, so should the new one. The shock and horror turns into acceptance.
But then, these are abnormal times, we tell ourselves. And they might not last and neither will these stories. However, this provides little comfort for I can remember when we first began to hear of ‘missing people’; when stories about the missing were read avidly because it was so new. Or when suicide bombings first happened in Pakistan. Then the times changed, leaders changed but we learnt to live with the missing and the suicide bombers. Times don’t last necessarily but the abnormal soon becomes normal.
The writer is a journalist.
Published in Dawn, August 19th, 2025
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On a wing and a prayer – Pakistan
WHEN most European countries and Volodymyr Zelensky were praying together with American neocons for the collapse of Vladimir Putin’s Alaska summit with Donald Trump, India was vocal in hoping for its success. The Indian idea was laudable, only the argument was a tad self-regarding. If the talks ended on a positive note, assorted Indian analysts reasoned, the impugned oil trade with Russia would no longer draw Trump’s ire. Putin would have saved the day for New Delhi.
On a wing and a prayer, the Modi foreign policy has bodily lifted its model from international sports contests where the ousted team pulls out its pocket calculators to desperately speculate its chance of returning to the contest should some other team beat another team. China is also affected by Trump’s frowning on its Russian oil imports. But the Communist Party-backed Global Times headline seemed in no tearing hurry to eye Beijing-centred success or failure in the otherwise important US-Russia talks. All the paper said was: “Trump and Putin addressed a joint press conference.”
And that is more or less what we know did happen. Much else is speculative. It is evident, Prime Minister Modi’s foreign policy prefers to ride piggyback on future outcomes over which it exerts no control. This is not how it used to be. A vital difference has emerged between then and now.
Indira Gandhi took Soviet help to bridge military and economic gaps. Yet she censured Moscow when the ally invaded Afghanistan. Nehru had the best of relations with Britain and even made India a member of the Commonwealth for which he was criticised roundly by his leftist supporters. Majrooh Sultanpuri found himself writing some memorable songs for the blockbuster movie Andaz from prison where he was sent for penning an acerbic poem against Nehru’s Commonwealth membership. But even as a member of the Commonwealth Nehru stoked the anti-colonial fervour in Asia and Africa, which won him lifelong friendships in the Global South.
Why is it so difficult to instil a simple, inexpensive idea for diplomacy?
Nehru supported the rise of China as a major post-colonial power but was misled by a combination of historians and cartographers into laying claim on tracts of Tibet that China had refused to accept during British rule. Nehru paid the price for his decision, until his grandson travelled to shake hands with Deng Xiaoping in a memorable move in 1988. Even Atal Bihari Vajpayee decided for better or worse to accept the heavy cost of declaring India a nuclear power even though he slipped up by explaining to Bill Clinton that the bomb was aimed at China. Everyone did what they deemed good for the country, which can’t be said of Narendra Modi. He has been doing whatever he could to appease the US until Trump poured cold water on the enthusiasm.
And yes, Indira Gandhi waged a decisive war on Pakistan but bore no ill will towards its people. She had a landmark meeting with Z.A. Bhutto in Shimla. Likewise, Rajiv Gandhi and Benazir Bhutto had a widely cheered rendezvous in Pakistan. Vajpayee and Manmohan Singh came close to resolving the Kashmir issue and, importantly, they did so with the help and support of their people, not of a foreign prompter. That’s what is missing in the pocket calculator diplomacy today, the engagement of the people on both sides of the equation, be it with Pakistan, or Bangladesh or Sri Lanka. India’s military has a problem with Pakistan’s military. But it’s Pakistan’s people that are known to have shown the door to many dictators, military or civilian. Modi has sidelined people on both sides. Faiz Ahmed Faiz’s daughters were denied visas for the first time in India’s history. Now, Modi has announced an iron dome-like project to protect the country from enemy attacks. Many see it as a wasteful idea given the hammering a heavily guarded Israel took from Iran recently.
Why is it so difficult to instil a simple, inexpensive idea for diplomacy? Why not let the masses — as opposed to state-backed mobs — take the initiative to build inevitable excellent ties, and see the menace called terrorism vanish in a jiffy?
Many current foreign policy preferences are, of course, rooted in Modi’s ideological pursuit of Hindutva. Or more accurately, it’s about marrying big business with Hindutva and passing it off as national interest. Of course, other than pervasive corruption, this has led to little else, as can be gleaned from the criminal cases in the US involving a major tycoon.
Bureaucracies, too, play a role in the wrack and ruin of India’s fair name. Inured to the social costs that state policies incur, they formulate or conjure ‘national interest’ from personal expediencies or biases, which currently seem to be heavily tilted towards the West. Much has been said about Modi’s Mittyesque media, which cut a sorry figure in the recent military engagement with Pakistan. But what does one make of respected current and former diplomats? One such served in Islamabad as high commissioner. In his view, in the absence of a decisive military victory, India should periodically “mow the grass” in Pakistan, a phrase used by Israel for periodically raiding Gaza and killing Palestinians before the events of October 2023. Mow the grass in nuclear Pakistan?
India has experienced many economic woes, mostly caused by oil price fluctuations. When the prices went through the roof in 1990, and the USSR had all but disappeared, the country pawned gold reserves to stave off defaulting. People accepted it. V.P. Singh was prime minister when the oil crisis began. He announced rationing on petrol. People understood. There were regulations about using cars. People took it in their stride. Something has changed today. It’s more about guarding the interests of this or that business house refining Russian oil to ship it off to Europe. From the dominant Indian perspective, the Alaska summit was about Russian oil, sadly, not about saving the world from nuclear annihilation.
The writer is Dawn’s correspondent in Delhi.
jawednaqvi@gmail.com
Published in Dawn, August 19th, 2025
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Targeting a sugar metabolism pathway offers hope for treating rare and aggressive childhood cancer
A new study delving into the genetic drivers of a rare and aggressive childhood cancer called Malignant Peripheral Nerve Sheath Tumor (MPNST) has revealed metabolic frailties in the cancer cells that might be exploited to improved treatments for patients.
MPNST is a rare and deadly childhood cancer, which mainly affects teenagers and young adults. These tumors grow quickly, spread easily, and don’t respond well to current treatments. Metastasis is the leading cause of death in MPNST and there currently are no targeted treatments for metastatic disease.
The study, led by University of Iowa researchers Eric Taylor, PhD, professor of molecular physiology and biophysics, and Rebecca Dodd, PhD, associate professor of internal medicine, identifies a specific metabolic pathway that is critical for MPNST cells’ survival and growth, which could potentially be targeted with future therapies.
Targeting cancer metabolism to slow tumor progression
To better understand these tumors, the UI researchers used gene editing to create new research models that closely match the cancer-driving mutations found in patients. Using these models, they then applied state-of-the-art genomic and metabolomic tools to map the metabolic pathways that fuel tumor growth in MPNST.
The study, published in Science Advances, found that these cancers rely on a key metabolic pathway to help them survive oxidative stress and drive tumor growth. This pathway, known as the Pentose Phosphate Pathway (PPP), metabolizes sugar to produce a critical antioxidant molecule that the cancer cells require to combat oxidative stress. When the researchers blocked the PPP, the tumors grew more slowly and were more vulnerable to chemotherapy.
This is the first time this specific metabolic pathway has been linked to MPNST tumor growth, making it a completely new target for therapy in this cancer type. It opens the door to treatment strategies that haven’t been explored before and could lead to more effective treatments and better outcomes for patients who urgently need new options.”
Rebecca Dodd, PhD, associate professor of internal medicine, University of Iowa
The highly collaborative study combined Dodd’s expertise in cancer biology with Taylor’s expertise in metabolism. The lead author was UI graduate student Gavin McGivney, PhD, from Bayard in Guthrie County, Iowa, who was co-mentored by Dodd and Taylor. McGivney graduated from the UI Cancer Biology graduate program in 2024, and is now a postdoctoral scholar at University of Chicago. Dodd and Taylor are both members of UI Health Care Holden Comprehensive Cancer Center, and Taylor is a member of the UI Fraternal Order of Eagles Diabetes Research Center.
In addition to Dodd, Taylor, and McGivney, the research team also included UI researchers in the Departments of Internal Medicine, Molecular Physiology and Biophysics, and Radiation Oncology at the UI Roy J. and Lucille A. Carver College of Medicine. Researchers at Washington University School of Medicine, University of Texas MD Anderson Cancer Center, and the University of Toronto, were also part of the team.
The research was funded in part by grants from the Children’s Tumor Foundation, the National Institutes of Health, the American Heart Association, the U.S. Department of Defense, and the American Cancer Society through Holden Comprehensive Cancer Center.
Source:
University of Iowa Health Care
Journal reference:
McGivney, G. R., et al. (2025). Somatic CRISPR tumorigenesis and multiomic analysis reveal a pentose phosphate pathway disruption vulnerability in MPNSTs. Science Advances. doi.org/10.1126/sciadv.adu2906.
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Worst civilian era? – Newspaper
NONE of our past regimes established durable progress and many have even put us back. But perhaps only Zia’s era, our worst one by far, matches the reversals we have seen under the current hybrid set-up in just 18 months, contrary to claims of making major progress.
The main harm has been done to democracy as civilian sway is at its lowest in key areas. While our two oldest parties are ruling overtly, they seemed to have nixed the political progress of yore. They began by violating their Charter of Democracy oath not to win power with the establishment’s aid. In 2013, they had ensured our only fair civilian power transfer but won this time through arguably our most rigged poll since the 2002 one held under martial law. To end rigging by incumbents, both had adopted the global good model of neutral caretakers that bars them from joining the next set-up to reduce conflict of interest. But in 2024, they bent their own good law to induct caretakers in cabinets.
Our post-2009 higher judiciary hiring system too was among the best globally as its use of judicial and balanced bipartisan assembly committees ended the executive’s hold. But instead of improving it by adding merit criteria and open applications, they re-cemented the executive hold, which has harmed the judiciary. A crackdown is underway against the PTI, nationalist Baloch and KP groups and even ordinary citizens reminiscent of the Zia era. Media and other freedoms are being nixed via bad laws. While they had rightly criticised the PTI’s era for such political sins, their own have now left the former behind.
The government has achieved fragile economic stability but is clueless about durable growth. The real economic reversal, though, is the loss of ambition. CPEC, along with the Gulf inflows, was a solid way of industrialising. But 10 years later, greater attention is focused on US ties in controversial areas like crypto and natural wealth — a globally feared curse for misruled states like ours — plus remittances and establishment-led farming. The last seems to reflect a concern that greater industrialisation may bring in meritorious rulers, and so dubious sectors are a better focus for the rulers’ narrow interests. Zia had done the same. Ayub and Bhutto had at least adopted varied, though faulty, state-led ways to industrialise. But Zia moved the focus to predatory sectors such as US aid, real estate, etc.
The main harm has been done to democracy.
Insecurity is increasing and negatively affecting the gains of the 2008-18 era. While this set-up rightly pins the blame for this trend on the PTI-era hybrid government for resettling TTP fighters in KP, its own steps have exacerbated matters. Its forcible approach to Balochistan, even towards peaceful marchers, is pushing common people away from normal politics. Oddly, we tell other states facing terrorism to address the root causes but avoid doing so ourselves in Balochistan. Many say the state’s distinction among ‘good and bad’ Taliban stokes terrorism in KP and new operations will only add to people’s miseries.
The big reversal externally is the rekindling of that old, on-off romance with the US via personal, non-civilian ties instead of normal state ties. While the regime calls it progress, many vividly recall the damage three decades of such ties did. The chances of us being fourth time lucky are slim as the key actors on both sides resemble past ones. For us, it’s again a set-up desperately seeking global patrons to overcome its low domestic legitimacy and su-rvive. For the US, it’s a very short-visioned and self-centred (Trump) regime even by US norms. So, many fear the results may benefit our ruling elites but harm the masses.
So, all the reversals approach those in non-civilian eras, making one wonder if this will be the worst civilian era ever and how much more harm it will cause. Sages say talks are the best way out of the mess. But strong autocracies don’t voluntarily concede; instead, they use talks to pressure dissidents to yield and give themselves legitimacy. The current set-up might only accept calls for fair polls, civilian sway, judicial freedom and end to crackdowns if dissidents form a strong joint platform, which seems unlikely for now.
Though the nation is angry, it remains divided. Diverse angry groups are angry on diverse issues and often don’t relate to and even oppose the basis of anger of other angry groups. So, regime may cave in under the weight of its own missteps, as always pushed gently and jointly by dissidents.
The writer has a PhD from the University of California, Berkeley, in political economy and 25 years of grassroots to senior-level experiences across 50 countries.
murtazaniaz@yahoo.com
X: @NiazMurtaza2
Published in Dawn, August 19th, 2025
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