Category: 3. Business

  • Ipsen Acquires ImCheck Therapeutics: A&O Shearman Advises Deal

    Ipsen Acquires ImCheck Therapeutics: A&O Shearman Advises Deal

    This acquisition is focused on the clinical-stage program ICT01 in acute myeloid leukemia (AML) targeting patients who are ineligible for intensive chemotherapy or targeted treatments. ICT01 is a first-in-class monoclonal antibody whose data from an ongoing trial showed a high treatment response, which could make it a new standard of care for acute myeloid leukemia, an aggressive blood cancer affecting older adults.

    The transaction is expected to close by the end of Q1 2026, subject to fulfilment of customary closing conditions, including the required regulatory and governmental approvals under French and U.S. regulations.

    Marc Castagnède, partner at A&O Shearman, said: “This transaction clearly demonstrates our ability to support clients in executing complex, strategic deals in highly specialized sectors such as life sciences. We are proud to have advised Ipsen on this landmark acquisition, which sits at the heart of biotech innovation and therapeutic advancement.”

    The A&O Shearman team is being led by M&A partner Marc Castagnède with support from M&A senior associate Antoine Messent, and associate Fatima Ahamada.

    Other members of the Paris team involved in the transaction include partner Olivier Picquerey and senior associate Antoine Tantaro on employment matters; partners Laëtitia Bénard and Charles Tuffreau, associate Manon Perret and consultant Marianne Delassaussé on IP matters; senior associate Clémence d’Almeida on antitrust matters; counsel Luc Lamblin and associate Charles-Hugo Lerebour on regulatory and FDI matters; partner Laurie-Anne Ancenys and associate Thomas Feigean on IT and data aspects; and partner Charles del Valle on tax matters.

    Support was also provided by the A&O Shearman US corporate and antitrust teams.

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  • ‘Attacks will get through’: head of GCHQ urges companies to do more to fight cybercrime | Cybercrime

    ‘Attacks will get through’: head of GCHQ urges companies to do more to fight cybercrime | Cybercrime

    Companies need to do more to mitigate the potential effects of cyber-attacks, the head of GCHQ has said, including making physical, paper copies of crisis plans to use if an attack brings down entire computer systems.

    “What are your contingency plans? Because attacks will get through,” said Anne Keast-Butler, who has headed GCHQ, the British government’s cyber and signals intelligence agency, since 2023.

    “What happens when that happens to you in a company, have you really tested that?” said Keast-Butler, speaking on Wednesday at a London conference organised by the cybersecurity company Recorded Future. “Your plans … have you got them on paper somewhere in case all your systems really go down? How will you communicate with each other if you’re completely reliant on a system that actually you shut down?”

    Last week, the National Cyber Security Centre, which is part of GCHQ, announced figures showing that “highly significant” cyber-attacks have risen by 50% in the past year. Security and intelligence agencies are now dealing with a new attack several times per week, the figures showed.

    Keast-Butler said the government and business needed to work together to tackle future attacks and improve defensive systems, as modern technology and artificial intelligence make the threats more diffuse and reduce “the entry level capability” that malicious actors need to do damage. She said work with internet service providers to block malicious websites at source was “blocking millions of potential hits” but said major companies needed to do much more to protect themselves.

    On Tuesday, a report by the Cyber Monitoring Centre (CMC) said the hack of Jaguar Land Rover had cost the UK economy an estimated £1.9bn, which could make it the most costly cyber-attack in British history.

    JLR had to shut down systems across all its factories and offices after the attack in August, and may not be able to return to normal production capacity until January.

    Keast-Butler said “[there are] far, far, far more attacks that get stopped than the ones that we’re focusing in on”, but added that the increased publicity around the JLR and several other major cyber-attacks provided a good moment to ram home the importance of cybersecurity protocols.

    She said she spoke regularly to CEOs of major companies and one of her messages to them was that they need to put people who understand cybersecurity on their boards. “Quite often, the way boards are configured, they don’t have people who will know the right questions to be asking. So the interest is there, but the right questions don’t get asked,” she said.

    Earlier this year, the Co-op Group suffered a cyber-attack that cost it up to £120m in lost profits and compromised the personal data of some of its members. Shirine Khoury-Haq, the group’s CEO, released an open letter in the aftermath detailing the importance of cybersecurity drills to build strategy on how to deal with an attack.

    “The intensity, urgency and unpredictability of a live attack is unlike anything you can rehearse. That said, those drills are invaluable; they build muscle memory, sharpen instincts, and expose vulnerabilities in your systems,” wrote Khoury-Haq.

    Keast-Butler encouraged companies to share information on attacks with government agencies, saying that “safe spaces” had been set up to enable them to do so without the risk of giving away commercially sensitive information to competitors.

    “I think sometimes people are a bit too reticent to come forward because there’s a sort of personal thing on them or their company as a whole. And that doesn’t help any of us, because then they’re not making the kind of long-term strategic systems changes that we can help out with,” she said.

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  • WPP unveils WPP Open Pro – WPP

    1. WPP unveils WPP Open Pro  WPP
    2. WPP boosts AI marketing with $400mn Google deal  Financial Times
    3. WPP’s AI Tool Lets Brands Skip Agencies for Ad Creation  WebProNews
    4. WPP cuts out the agency to help brands create their own ads with AI  Yahoo Finance
    5. Ad agency WPP Commits to Spend $400 million on Google AI  The Information

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  • Tiragolumab Disappoints in Untreated Advanced HCC – Medscape

    1. Tiragolumab Disappoints in Untreated Advanced HCC  Medscape
    2. TRIPLET-HCC at ESMO 2025: Adding Ipilimumab to Atezolizumab–Bevacizumab Fails to Improve Outcomes in Unresectable HCC  Oncodaily
    3. ESMO 2025: Roche’s TIGIT failures continue, this time in liver cancer  Yahoo
    4. Tiragolumab Regimen Misses PFS End Point in Hepatocellular Carcinoma  CancerNetwork

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  • Remarks by Philip R. Lane, Member of the Executive Board of the ECB, on the occasion of the conferral of the 2025 Pádraig Ó hUiginn Award

    Remarks by Philip R. Lane, Member of the Executive Board of the ECB, on the occasion of the conferral of the 2025 Pádraig Ó hUiginn Award

    Dublin, 23 October 2025

    It is an honour to receive the Pádraig Ó hUiginn Award. Pádraig Ó hUiginn and the previous recipients of this award (John Bruton, Catherine Day and Michael Noonan) have all contributed to the development of Irish and European policy frameworks for the financial services sector.

    A successful financial services sector requires the sound underpinning provided by high-quality public institutions and sustainable public finances. In particular, the financial services industry is characterised by distinct complementarities between the private sector and the public sector: commercial providers of financial services benefit from a public regulatory and supervisory framework that maintains prudential standards, protects consumers and underpins financial stability.[1]As the severe costs of the Irish banking crisis so painfully demonstrated, it is neither in our collective interest as a society nor in the interest of the financial services sector to be complacent about the essential contribution of financial regulation to the long-term health of the sector.

    At the same time, the regulatory and supervisory system should neither deter new entrants nor inhibit the capacity of the financial services sector to innovate and roll out new technologies. In adapting to a rapidly-digitalising financial system, it is in the shared interest of regulators and financial services firms to make sure that this digital transition takes place without putting at risk the essential features of a well-regulated financial system.

    In the context of financial digitalisation, let me also highlight that the European Central Bank (ECB) is working hard to make sure that central bank money – which provides the underlying foundations for the entire financial system – is also modernised. In particular, the digital euro would provide a digital version of central bank money, maintaining the essential feature of the monetary system that commercial bank money is fully interchangeable at par with central bank money.[2]

    In terms of wholesale transactions, the ECB has also approved a plan that will enable distributed ledger technology (DLT) transactions to be settled using central bank money.[3]The initiative follows a two-track approach: the first track “Pontes” provides a short-term offering to the market – including a pilot phase – and the second track “Appia” focuses on a potential long-term solution. The decision is in line with the commitment of the Eurosystem to supporting innovation without compromising on safety and efficiency in financial market infrastructures.

    In addition to the digitalisation agenda, let me also highlight another fundamental and, indeed, inter-connected challenge for the financial services sector: it is clear that geopolitical developments have made it all the more urgent to make substantial progress on integrating the European financial system.[4]In particular, it is critical to complete the savings and investments union and the banking union to an ambitious timetable.

    A more integrated and more fully developed European financial system is in our collective interest. An integrated European financial system will: improve market efficiency; offer greater opportunities to European firms to raise both equity and debt financing; and, through the benefits of economies, make it easier for European households to hold diversified financial portfolios, while also lowering transaction costs.[5] In addition, an integrated financial system will make Europe more attractive for global investors, allowing Europe to gain from an improvement in the financial “terms of trade”. In terms of public policy objectives, an integrated European financial system will also support the large-scale funding needs of the green transition and the scaling up of the European defence industry, including through greater scope for joint funding of pan-European initiatives.[6]

    These topics are high on the agenda for today’s European Council and Euro Summit meetings in Brussels, reflecting the political urgency in building an integrated-but-open European digital-ready financial system that ensures sovereignty and resilience, improving the performance of the European economy and making Europe a more attractive destination for global investors.

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  • Super Micro cuts first-quarter revenue forecast – Reuters

    1. Super Micro cuts first-quarter revenue forecast  Reuters
    2. Supermicro (NASDAQ: SMCI) reports $12B design wins, reiterates at least $33B revenue  Stock Titan
    3. Super Micro slumps after announcing preliminary Q1 net sales far below Wall Street’s expectations  Sherwood News
    4. Super Micro Computer stumbles on Q1 revenue shortfall  Investing.com

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  • S&P Global Partners with Eightfold AI on Innovative Talent Intelligence Platform, Advancing Capabilities of Company’s Future-Ready Workforce

    S&P Global Partners with Eightfold AI on Innovative Talent Intelligence Platform, Advancing Capabilities of Company’s Future-Ready Workforce

    • Strategic partnership leverages Eightfold AI’s native talent intelligence to strengthen workforce development for the future
    • Engagement empowers S&P Global employees with skills-based career mobility and personalized learning

    NEW YORK, Oct. 23, 2025 /PRNewswire/ — S&P Global (NYSE: SPGI) today announced a strategic collaboration with Eightfold AI, a leading AI-native talent intelligence platform, to strengthen workforce development and enable skills-based career mobility across the company.

    S&P Global logo (PRNewsfoto/S&P Global)

    Adopting Eightfold AI’s Talent Design framework will help S&P Global blend human expertise with advanced AI capabilities to enhance skills-based career architecture, benchmark roles against global markets, and unlock data-driven insights to prepare its workforce for the future of work.

    S&P Global will leverage Eightfold AI’s expertise in navigating the evolving workforce challenges of today’s global economy to empower employees to discover new internal career opportunities, access personalized learning, and build future-ready skills aligned with the organization’s business needs. Key capabilities include:

    • Skills-based career pathing that connects employees with career opportunities across the organization
    • Curated learning and upskilling recommendations to build individualized future-ready capabilities
    • Talent intelligence at scale to increasingly align S&P Global’s workforce development with long-term business strategy

    “S&P Global has long championed AI adoption and upskilling as part of our workforce strategy through our EssentialTECH education, mandatory ‘AI for Everyone’ employee training, and internal tools including Kensho Spark Assist. This partnership with Eightfold AI marks another milestone in our commitment to propelling our people forward by equipping our workforce with the skills and opportunities to thrive during this era of transformative change,” said Girish Ganesan, Chief People Officer at S&P Global. “We are creating new pathways for career growth and internal mobility while building capabilities that accelerate innovation and deliver even greater impact for our customers; Eightfold AI’s skills-based approach complements our existing training programs and offerings and reinforces our vision for a future-ready workforce.”

    “We are pleased to work with S&P Global on this workforce intelligence AI initiative, which aligns perfectly with its stature as a leading provider of essential intelligence to global markets,” said Ashutosh Garg, Co-Founder and CEO of Eightfold AI. “Eightfold AI believes that valuing human insight is indispensable to successful AI-driven initiatives and this collaboration showcases the power of combining human insight with AI to unlock additional potential.”

    To learn more about S&P Global’s talent and career opportunities, visit: www.spglobal.com/careers

    Learn more about Artificial Intelligence at S&P Global:
    https://www.spglobal.com/en/research-insights/market-insights/artificial-intelligence

    Media Contact:

    Orla O’Brien 
    S&P Global
    +1 857-407-8559
    orla.obrien@spglobal.com 

    About S&P Global

    S&P Global (NYSE: SPGI) provides essential intelligence. We enable governments, businesses and individuals with the right data, expertise and connected technology so that they can make decisions with conviction. From helping our customers assess new investments to guiding them through sustainability and energy transition across supply chains, we unlock new opportunities, solve challenges and accelerate progress for the world.

    We are widely sought after by many of the world’s leading organizations to provide credit ratings, benchmarks, analytics and workflow solutions in the global capital, commodity and automotive markets. With every one of our offerings, we help the world’s leading organizations plan for tomorrow, today. For more information, visit www.spglobal.com.

     

    SOURCE S&P Global

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  • The next space race will be won at night

    On the lunar surface, every “night” lasts roughly 14 Earth days. With the sun out of view, temperatures plunge to nearly minus 300 degrees Fahrenheit, solar panels stop generating power, batteries drain and electronics freeze. In 2024 and 2025, the United States made its return to the moon with three commercial landers thanks to investments by NASA and industry. Each completed its primary mission but lacked the thermal and power systems needed to survive the lunar night, dying within two weeks. By contrast, Chinese landers equipped with nuclear power systems have remained operational for more than 2,400 days. 

    Since 2013, multiple Chinese landers have used radioisotope power systems, or nuclear batteries, to keep vehicles and infrastructure warm and operational through the lunar night. Chang’e-4 has been continuously operating for more than five years on the far side of the moon, out of sight of U.S. monitoring capabilities. The more advanced Chang’e 8 will reach the south pole in 2028 to test resource extraction, paving the way for a permanent Chinese lunar base.

    A recent Commercial Space Federation comprehensive assessment of China’s space progress stated that “China’s ambitions to develop super-heavy lift vehicles, autonomous in-situ resource utilization, and nuclear power on the moon raises strategic challenges to U.S. technological advantages.” If the U.S. is to catch up, it needs to embrace nuclear power as soon as possible.

    NASA is meeting the moment with plans to launch a fission reactor to the south pole of the moon by 2030 under the Fission Surface Power (FSP) program. FSP will be a breakthrough, providing continuous power through the lunar night and enabling sustained lunar operations for years to come for the Artemis program. 

    However, China’s success on the moon makes it an imperative that the U.S. not wait until 2030. Multiple U.S. missions across the lunar surface planned in the coming years can use nuclear energy, enabling us to do substantially more on the moon and to surpass China’s current lead.

    The space industry is already preparing to meet this need with transportation, power and long-duration infrastructure. Significant private capital invested alongside government funding has matured the technology and secured the supply chain with successful prototypes demonstrated, nuclear fuel sources secured and facilities established. Coupled with the now-successful Commercial Lunar Payload Services (CLPS) partnership between NASA and U.S. commercial companies, landing a nuclear battery on the lunar surface could be achieved within two years.

    Establishing survive-the-night capability on the lunar surface with nuclear batteries is complementary to development of a nuclear reactor. A recent U.S. Department of Energy study proposed a “commercially led radioisotope power system demonstration to… derisk the broader space nuclear ecosystem, especially if larger efforts encounter delay.” 

    Nuclear batteries will enable new kinds of missions as we expand exploration not only across the moon but in the rest of the solar system — powering operations in multiple lunar locations, establishing distributed science networks, and supporting our ambitions for Mars. For example, U.S. efforts to utilize lunar resources, such as water, metals and helium-3 will require power and long duration operations, making night survival essential. NASA’s various mission directorates for exploration, science and technology will all directly benefit from this capability.

    The Department of Energy also made the case to act with urgency, saying in a recent report that “the United States cannot afford to delay while others shape the rules of the road and claim first-mover advantage.” In this lunar race, it is not about who lands on the moon first, it is about who lands and stays there. Staying there means a continuous U.S.-led strategic presence on multiple lunar sites to secure our rights to conduct science, exploration and resource utilization. Such a continuous U.S. presence requires continuous power.

    For the U.S. to win the next space race, we need to deploy sustained power to stay on the moon, or risk ceding space leadership to China.

    Alan Campbell is the Director of Growth and Capture for Space Systems at Draper. Alan is responsible for driving Draper’s strategy to provide mission-enabling technology across the Space industry, inclusive of civil, commercial and national security space customers. Previously, Alan led Draper’s support to NASA’s CLPS program including Draper’s CP-12 task order award.

    A.C. Charania is the Senior Vice President of Space Business Development at Zeno Power. Most recently, he served as NASA’s Chief Technologist, advising the agency on technology strategy. He previously worked in the commercial aerospace industry for more than two decades delivering disruptive innovations in lunar exploration, commercial spaceflight, planetary defense, aviation autonomy and launch vehicle/hypersonic programs. 

    Tim Crain is the Co-Founder and Chief Growth Officer of Intuitive Machines. A Ph.D. in aerospace engineering with a specialization in precision navigation and timing, Tim formerly served as a key technology program manager within NASA where he helped shape missions like the Mars Science Lander and Orion spacecraft. Tim brings deep expertise in scalable innovation across the aerospace, energy and medical industries, and expertise in flight dynamics including guidance, navigation and control as well as automated flight systems, high-fidelity system analysis and optimization and precision navigation and timing.

    Elizabeth Kryst is the CEO of ispace-U.S. Before joining ispace-U.S., Elizabeth has held various leadership roles in the aerospace sector, from new product introduction to program management and strategic planning in advanced material science and environmental sciences. Most recently served as the Chief of Staff – Vice President of Business Operations for World View, an Aerospace startup company pioneering un-crewed high altitude stratospheric flight systems for a myriad of remote sensing applications. She holds a master’s degree in engineering (MEng) from Arizona State University and a Bachelor’s degree in Chemistry from the University of Illinois at Chicago.

    SpaceNews is committed to publishing our community’s diverse perspectives. Whether you’re an academic, executive, engineer or even just a concerned citizen of the cosmos, send your arguments and viewpoints to opinion@spacenews.com to be considered for publication online or in our next magazine. The perspectives shared in these opinion articles are solely those of the authors.

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  • Mitigating voluntary carbon market risks: Insurance strategies for corporate climate goals

    Mitigating voluntary carbon market risks: Insurance strategies for corporate climate goals

    As new risks associated with environmental initiatives materialize, the insurance market is adapting to better address these exposures. One notable development is the introduction of carbon credit insurance solutions, designed to help mitigate the specific risks faced by companies engaging in the voluntary carbon market (VCM). The VCM is a decentralized marketplace where each carbon credit represents one ton of carbon dioxide (or equivalent greenhouse gases) either removed or avoided. Carbon credit insurance may help transfer some of the risks associated with buying, investing, or selling carbon credits within this unregulated environment, with the goal of providing greater security and confidence for market participants.

    The growing market for carbon credit insurance

    Companies can face numerous risks when purchasing carbon credits to offset their emissions. These include the invalidation of credits due to fraud, changes in accounting methodologies, or other reasons that lead to the withdrawal of credits previously issued and validated by accrediting bodies. Additional risks include late delivery of credits by project developers and the potential for reversals, where sequestered carbon is re-released into the atmosphere, often due to natural disasters or other unforeseen events. 

    Reversal is a particularly significant risk, especially in regions prone to natural catastrophes. Forest-based offset projects are especially vulnerable; wildfires, for example, can destroy trees that have sequestered carbon, resulting in the release of stored emissions back into the atmosphere. If a company relies on these offsets to meet regulatory or voluntary commitments, such reversals could have serious consequences, including reputational damage, financial penalties, or loss of credibility. 

    While the VCM remains largely unregulated, the potential impact of reversals underscores the need for risk mitigation. Insurance products are emerging to provide coverage against these events, offering companies potential financial protection should a reversal occur. This may allow organizations to repurchase credits or receive indemnity for their investments, with the intent of helping to maintain confidence in their offsetting strategies.

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  • Prada Group continues solid performance in 9M 2025

    Prada Group continues solid performance in 9M 2025

    Patrizio Bertelli, Prada Group Chairman and Executive Director, commented: “The consistency of our results, in a complex macroeconomic environment, confirms the strength of our brands and the validity of our strategy. With the one just closed, the Group has delivered 19 quarters of uninterrupted growth. We continue to focus on creativity, product excellence and craftsmanship as foundations for enduring relevance and long-term development. These principles guide us as we navigate an evolving landscape with confidence, discipline and responsibility.”

    Andrea Guerra, Group Chief Executive Officer, added: “Our performance confirms the health of our brands and further solid, diligent execution by our teams. Prada accelerated versus the previous quarter; Miu Miu has maintained a sustained growth trajectory for 4 years, including in this quarter that was facing triple-digit comps. Despite a still challenging environment, we remain confident in our trajectory, focusing on products and experiences that spark emotional engagement, while further improving our speed and flexibility.”


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