Chimeric Therapeutics (ASX:CHM) has signed a Letter of Intent (LOI) with Viral Vector Manufacturing Facility Pty Ltd (VVMF) to establish a strategic partnership focused on the development and Good Manufacturing Practice (GMP) production of Lentiviral vectors in Australia.
Under the agreement, VVMF will support process development, technology transfer and GMP-grade manufacturing of Lentiviral vectors for Chimeric’s clinical-stage chimeric antigen receptor T-cell (CAR-T) therapy programme. Viral vectors are essential in producing CAR-T therapies, which are revolutionising cancer treatment worldwide.
“We’re pleased to partner with VVMF as we continue to advance our CAR-T cell therapy programmes,” said Chimeric Therapeutics CEO Dr Rebecca McQualter. “Having access to local, GMP-grade viral vector manufacturing not only strengthens our supply chain but also supports the broader goal of building world-class advanced therapy capabilities here in Australia.”
VVMF CEO Stephen Thompson said the collaboration would strengthen sovereign manufacturing and create high-value jobs in Western Sydney. “This collaboration allows us to demonstrate our capability to develop and manufacture GMP-grade viral vectors for the global cell and gene therapy marketplace,” he said.
The agreement was described as a milestone for Australia’s growing advanced manufacturing sector and the development of Advanced Therapy Medicinal Products (ATMPs) — innovative medicines derived from genes, cells, or engineered tissues. These therapies are opening new possibilities for treating cancer, neurodegenerative, and cardiovascular diseases.
Supported by strong R&D incentives, a pragmatic regulatory environment and a mature clinical trial ecosystem, Australia is well positioned to become a global hub for advanced therapy development and manufacturing.
Amandip Kaur said her pharmacy in St Dennis made a loss on half of the medicines it dispenses
A pharmacist has warned more chemists in the South West could be forced to shut because of funding pressures, without urgent action from the government.
The National Pharmacy Association said about 27 had closed in Cornwall and Devon between October 2022 and June this year.
Those in the industry said the cost of up to half of the medicines they have to provide was no longer covered by the amount of NHS funding they received.
The Government said it had invested £3.1bn into pharmacies this year and they were central to its 10 year plan for the future of local healthcare.
Amandip Kaur, from Bann’s Pharmacies Limited who run the pharmacy in St Dennis, said the current situation was “unsustainable.”
She said: “There is no profit margin for the pharmacist and the dispensing fees we get is nothing. It really does not cover the cost of running the pharmacy.”
She said “40 to 50 percent” of the medicines they were purchasing were not covered by the amount the NHS was paying them.
“It really needs to be looked into by the government sooner rather than later,” she added.
Owners said it was difficult to cover the running costs of independent pharmacies like in St Dennis
Nick Kaye, a pharmacist in Newquay who represents the National Pharmacy Association said: “Up to 63 percent of our members may be at risk of closing over the next 12 months.
“People will do loads of things to keep them going – borrow money from family members, re-mortgage, cash in pensions. Which is a really difficult situation to be in and it can be perilous.”
He called on the government to stabilise the current situation with the cost of dispensing prescriptions.
“The government’s own independent economic review recognized a £2.6bn shortfall in community pharmacy funding so what we really need is a roadmap to make sure that bridge is gapped over the coming years,” he added.
‘Largest uplift’
A Department of Health and Social Care spokesperson said: “Community pharmacists are at the heart of local healthcare.
“As set out in the 10 Year Health Plan we want them to play a bigger role as we shift care out of hospitals and into the community.
“This year we increased funding to community pharmacies to almost £3.1 billion – representing the largest uplift in funding of any part of the NHS for 2025/2026 – providing patients with more services closer to home and freeing up GP appointments.”
SAN ANTONIO — SAN ANTONIO (AP) — On a scorching hot Saturday in San Antonio, dozens of teachers traded a day off for a glimpse of the future. The topic of the day’s workshop: enhancing instruction with artificial intelligence.
After marveling as AI graded classwork instantly and turned lesson plans into podcasts or online storybooks, one high school English teacher raised a concern that was on the minds of many: “Are we going to be replaced with AI?”
That remains to be seen. But for the nation’s 4 million teachers to stay relevant and help students use the technology wisely, teachers unions have forged an unlikely partnership with the world’s largest technology companies. The two groups don’t always see eye to eye but say they share a common goal: training the future workforce of America.
Microsoft, OpenAI and Anthropic are providing millions of dollars for AI training to the American Federation of Teachers, the country’s second-largest teachers union. In exchange, the tech companies have an opportunity to make inroads into schools and win over students in the race for AI dominance.
AFT President Randi Weingarten said skepticism guided her negotiations, but the tech industry has something schools lack: deep pockets.
“There is no one else who is helping us with this. That’s why we felt we needed to work with the largest corporations in the world,” Weingarten said. “We went to them — they didn’t come to us.”
Weingarten first met with Microsoft CEO Brad Smith in 2023 to discuss a partnership. She later reached out to OpenAI to pursue an “agnostic” approach that means any company’s AI tools could be used in a training session.
Under the arrangement announced in July, Microsoft is contributing $12.5 million to AFT over five years. OpenAI is providing $8 million in funding and $2 million in technical resources, and Anthropic has offered $500,000.
With the money, AFT is planning to build an AI training hub in New York City that will offer virtual and in-person workshops for teachers. The goal is to open at least two more hubs and train 400,000 teachers over the next five years.
The National Education Association, the country’s largest teachers union, announced its own partnership with Microsoft last month. The company has provided a $325,000 grant to help the NEA develop AI trainings in the form of “microcredentials” — online trainings open to the union’s 3 million members, said Daaiyah Bilal, NEA’s senior director of education policy. The goal is to train at least 10,000 members this school year.
“We tailored our partnership very surgically,” Bilal said. “We are very mindful of what a technology company stands to gain by spreading information about the products they develop.”
Both unions set similar terms: Educators, not the private funders, would design and lead trainings that include AI tools from multiple companies. The unions own the intellectual property for the trainings, which cover safety and privacy concerns alongside AI skills.
The Trump administration has encouraged the private investment, recently creating an AI Education Task Force as part of an effort to achieve “global dominance in artificial intelligence.” The federal government urged tech companies and other organizations to foot the bill. So far, more than 100 companies have signed up.
Tech companies see opportunities in education beyond training teachers. Microsoft unveiled a $4 billion initiative for AI training, research and the gifting of its AI tools to teachers and students. It includes the AFT grant and a program that will give all school districts and community colleges in Washington, Microsoft’s home state, free access to Microsoft CoPilot tools. Google says it will commit $1 billion for AI education and job training programs, including free access to its Gemini for Education platform for U.S. high schools.
Several recent studies have found that AI use in schools is rapidly increasing but training and guidance are lagging.
The industry offers resources that can help scale AI literacy efforts quickly. But educators should ensure any partnership focuses on what’s best for teachers and students, said Robin Lake, director of the Center on Reinventing Public Education.
“These are private initiatives, and they are run by companies that have a stake,” Lake said.
Microsoft CEO Brad Smith agrees that teachers should have a “healthy dose of skepticism” about the role of tech companies.
“While it’s easy to see the benefits right now, we should always be mindful of the potential for unintended consequences,” Smith said in an interview, pointing to concerns such as AI’s possible impact on critical thinking. “We have to be careful. It’s early days.”
At the San Antonio AFT training, about 50 educators turned up for the three-hour workshop for teachers in the Northside Independent School District. It is the city’s largest, employing about 7,000 teachers.
The day started with a pep talk.
“We all know, when we talk about AI, teachers say, ‘Nah, I’m not doing that,’” trainer Kathleen Torregrossa told the room. “But we are preparing kids for the future. That is our primary job. And AI, like it or not, is part of our world.”
Attendees generated lesson plans using ChatGPT, Google’s Gemini, Microsoft CoPilot and two AI tools designed for schools, Khanmingo and Colorín Colorado.
Gabriela Aguirre, a 1st grade dual language teacher, repeatedly used the word “amazing” to describe what she saw.
“It can save you so much time,” she said, and add visual flair to lessons. She walked away with a plan to use AI tools to make illustrated flashcards in English and Spanish to teach vocabulary.
“With all the video games, the cellphones you have to compete against, the kids are always saying, ‘I’m bored.’ Everything is boring,” Aguirre said. “If you can find ways to engage them with new technology, you’ve just got to do that.”
Middle school teacher Celeste Simone said there is no turning back to how she taught before.
As a teacher for English language learners, Simone can now ask AI tools to generate pictures alongside vocabulary words and create illustrated storybooks that use students’ names as characters. She can take a difficult reading passage and ask a chatbot to translate it into Spanish, Pashto or other languages. And she can ask AI to rewrite difficult passages at any grade level to match her students’ reading levels. All in a matter of seconds.
“I can give my students access to things that never existed before,” Simone said. “As a teacher, once you’ve used it and see how helpful it is, I don’t think I could go back to the way I did things before.”
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The Associated Press’ education coverage receives financial support from multiple private foundations. AP is solely responsible for all content. Find AP’s standards for working with philanthropies, a list of supporters and funded coverage areas at AP.org.
Gold notched a new high above $4,300 an ounce on Friday and was poised for its best week in five years, as signs of weakness in U.S. regional banks, global trade frictions and expectations of more rate cuts sent investors flocking to the safe-haven metal.
Bloomberg | Bloomberg | Getty Images
Gold notched a new high above $4,300 an ounce on Friday and was poised for its best week in five years, as signs of weakness in U.S. regional banks, global trade frictions and expectations of more rate cuts sent investors flocking to the safe-haven metal.
Spot gold was up 0.3% at $4,336.18 per ounce, as of 0233 GMT, after reaching a fresh high of $4,378.69 earlier in the session. U.S. gold futures for December delivery jumped 1% to $4,348.70.
Bullion has risen about 8% so far this week in what would be its best week since March 2020, notching a record high in each session.
Spot silver fell 0.7% to $53.86 per ounce, but stayed on track for a weekly gain. Earlier in the session, prices reached a record high of $54.35, tracking the rally in gold and a short squeeze in the spot market.
“(For gold) $4,500 could arrive as a target perhaps sooner than expected, but much may depend upon how long concerns about U.S.-China trade and the government shutdown linger over the market for,” said KCM Trade Chief Market Analyst Tim Waterer.
China levelled fresh accusations against the U.S. of causing panic over its rare earth controls, while rejecting calls to reverse export curbs.
Meanwhile, Federal Reserve Governor Christopher Waller voiced support for another rate cut due to labour market concerns.
Investors are expecting a 25-basis-point reduction at the Fed’s Oct. 29-30 meeting and another reduction in December.
Elsewhere, Wall Street closed lower on Thursday, with signs of weakness in regional banks spooking investors already on edge over U.S.-China trade tensions.
“The flare-up in U.S. regional bank credit concerns has given traders one more reason to buy gold,” Waterer said.
Non-yielding bullion, which tends to do well in a low interest rate environment, has gained more than 65% year-to-date, driven by geopolitical tensions, aggressive rate-cut bets, central bank buying, de-dollarisation and robust exchange-trade fund inflows,
On the geopolitical front, U.S. President Donald Trump and Russian President Vladimir Putin agreed on Thursday to another summit on the war in Ukraine.
Western nations continued to pressure Russia over its oil sales, with Britain imposing sanctions on major Russian oil firms.
Platinum fell 0.7% to $1,701.0 and palladium lost 0.4% to $1,607.93. Both metals were headed for weekly gains.
Roula Khalaf, Editor of the FT, selects her favourite stories in this weekly newsletter.
The writer is a managing partner and head of research at Axiom Alternative Investments
The AT1 bond market does not have many friends. When Swiss authorities controversially wiped out $17bn of the Additional Tier 1 bonds issued by Credit Suisse, many claimed that the market was dead. As the argument went: “Surely no one would be foolish enough to read the terms and conditions and still buy bonds that can be worth zero overnight?”
Lots of people were, it turned out: since lows hit in the wake of the failure of Credit Suisse, a Bloomberg index of the price of the bonds is up 50 per cent. And 2024 still saw a near 60 per cent increase in issuance to €46bn, according to Barclays. This year issuance has reached €34bn.
AT1s were introduced as a form of supplementary bank capital, designed to be wiped out in a crisis to cover losses. They are crucial to reduce banks cost of equity and increase their capacity to lend. The issue with the Credit Suisse AT1s is whether the bonds were wiped out fairly. The Swiss Federal Court ruled on Tuesday that the treatment of the bonds was unlawful — a decision my investment firm supports as we own some bonds affected and are taking separate legal action. Now we are hearing a similar argument to the one made at the time of the Credit Suisse failure, only in reverse: if you cannot wipe out AT1 capital when an entity is a “gone concern”, the asset class is dead.
But the circumstances of the Credit Suisse saga are idiosyncratic. To simplify, Swiss regulator Finma argued that it had basically three grounds to wipe out the bonds: two contractual grounds based on the terms of the bonds, and one general legal right, as an authority overseeing the bank’s resolution. The court dismissed the contractual grounds with a reasoning that is strictly limited to the specifics of this case. The terms and conditions allowed the wipeout in two situations: i) a notification by Finma of the non-viability of the bank and request by it for the wipeout of both AT1 and Tier 2 bonds or ii) necessary state aid improving the capital of the bank. On the first point, the court noted that Finma issued no such notification and, incomprehensibly, did not wipe out Tier 2 bonds. It could have done so. On the second point, the court says that Credit Suisse only received liquidity, and liquidity does not improve capital.
The last nail in the coffin? Finma argued that, as AT1 eligible bonds, the terms were maybe unclear but should have allowed the wipeout. The court answered that Finma should not have authorised the bonds if they did not meet AT1 requirements.
The discussion on the “general legal right” is also very intriguing. There were many ways for the Swiss authorities to zero the bonds. Swiss banking law gives huge discretion to Finma as a resolution authority and the court points that it explicitly refused to declare a resolution event and wipe out the bonds, presumably to protect the shareholders who received $3.2bn from UBS in the takeover of Credit Suisse and would have been left with nothing in a resolution. Under the Swiss constitution, an infringement on property rights requires a law and emergency ordinances can only be used as a substitute if no law is readily available.
None of this has direct implications for the rest of Europe. European authorities have already proved that swift and strict application of resolution laws can be done with little litigation risk. Sberbank Europe was wound down in 2022 and even the fall of Banco Popular in 2017 did not leave many pathways for AT1 bondholders to pursue redress in court.
Where does this leave UBS? Our firm has an interest in the outcome as we own UBS bonds but hold short positions on the stock. It’s the big unknown, and the Swiss court was very careful to point out that it was not answering that question — yet. This is why it calls its own decision “partial”. But the full text of the ruling hints at three possibilities.
Ruling that the ordinance wiping out the bonds is null could simply mean that the bonds are reinstated and reintroduced in UBS’s balance sheet. Whether UBS could receive indemnification from the Swiss government, in the middle of the current tense discussion on massive new capital requirements for the bank is another story. But the court could also rule that the AT1s remain void and that its decision only opens the right to seek indemnification from Finma or from the now combined Credit Suisse-UBS.
Who pays what in that scenario remains highly speculative — not to mention that this complex decision is not final and Finma will appealed against it. The Credit Suisse AT1 saga is far from over.
Investors in the $2tn leveraged loan market have warned that the abrupt collapse of First Brands Group is an early sign of trouble for a market where hasty deals and hurried due diligence have become commonplace.
First Brands was among the largest issuers of loans bought by collateralised loan obligations, investment vehicles that buy up small slices of hundreds of individual corporate loans.
CLOs have become popular with insurers and other big investors who bet that by spreading their lending across many different companies they are protected from the pain of defaults in one or two businesses.
But the rapid bankruptcy of First Brands, a maker of antifreeze, windshield wipers and brake pads, has raised concerns over the rapid growth of the CLO market, which has provided almost unquenchable demand for the leveraged loans that private equity firms often use to finance their acquisition sprees. Some fund managers worry that a spate of CLO losses could cause Wall Street’s securitisation machine to sputter.
“Inside credit markets for more than a year, there has been a grudging recognition that there was and is a series of credit problems that could be substantial and could be dangerous to the overall economy,” said Andrew Milgram, chief investment officer of Marblegate Asset Management, a distressed-debt investor.
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First Brands’ downfall, just weeks after subprime auto lender Tricolor filed for bankruptcy amid allegations of fraud, has stoked concerns that the failures are unlikely to be isolated incidents.
“You’re not paid to do due diligence in this market,” an executive at a former lender to First Brands said.
First Brands had issued more than $5bn of senior and junior loans, which were bought up and held in dozens of CLOs issued by asset managers including PGIM, Franklin Templeton, Blackstone, CIFC, Oaktree and Wellington, according to a Morgan Stanley analysis.
Most of those vehicles have already realised their losses, selling out of the loans as First Brands’ problems came to light over the past two weeks. The loans are now changing hands at just cents on the dollar, with an implied loss of more than $4bn.
Those losses will principally hit the returns of CLO equity holders, which includes the managers of the structured credit vehicles themselves. CLOs are often 10 times leveraged, with $50mn of equity supporting a $500mn loan portfolio, for example. Defaults such as First Brands’ cut into that equity cushion, which exists to take the first loss and protect higher-rated investment grade tranches of the CLO.
Trading of those equity tranches is opaque, but investors said they had not yet seen money managers dumping those positions in secondary trades.
The sell-off in First Brands debt has started to weigh on the broader market, with PitchBook LCD data showing the US leveraged loan market is on pace for its biggest monthly loss since 2022.
“The two successive defaults of [First Brands] and Tricolor Auto brought into highlight potential irregularities and underwriting challenges in the credit market,” Bank of America strategist Pratik Gupta said. “The market has started to take a dim view of credit fundamentals.”
Despite the troubles at First Brands and Tricolor and pockets of weakness starting to appear in the US economy, the strong demand for higher-yielding investments such as leveraged loans has kept spreads on risky corporate debt at near-record low levels.
Leveraged loan issuance hit a record in the third quarter at $404bn, according to PitchBook LCD. However, investors say this feverish pace of issuance has meant deals — which a few years ago may have taken weeks or more to line up — are now often raced through.
When First Brands raised more than $750mn in March 2024 to fund an acquisition, it announced it was in the market for the debt financing on a Monday morning. Investors were allocated the loans before lunch on Friday of the same week. In total, more than 80 CLOs were exposed to First Brands, bankruptcy filings showed.
Demand has persisted despite some of the worst investor protections on record, according to Covenant Review. Lawyers for the industry say they have little power to push back against weak protections when willing buyers are so numerous.
First Brands debt offered attractive rates, with an interest rate 5 percentage points over the floating rate benchmark for the US dollar loans it issued in March 2024. When accounting for discounts investors received at the time of the capital raise, the loans yielded roughly 11 per cent.
Investors who have suffered losses on the loans say due diligence was not made a priority, with some investors taking comfort from the fact that larger managers with bigger teams of credit analysts had bought in.
But others saw red flags they said steered them away from the debt. The company was perpetually buying up smaller businesses and raising more debt to fund those takeovers. Investors said that made it difficult to assess how the underlying business was faring. Others pointed to the difference between the cash flows that First Brands generated and the profits it reported it was earning.
“Everything was adjusted,” one investor who decided against investing in First Brands debt said, referring to its profit statement. “Nothing tied to cash so it was virtually impossible” to analyse.
Josh Easterly, the chief investment officer of investment group Sixth Street, pointed to the fact that many CLO investment firms have just a handful of analysts covering their entire credit portfolios, which can include hundreds of different investments. Moody’s estimates roughly 2,000 companies issue debt that is bought by CLOs in the US.
“When the tide goes out . . . things are going to come out,” Easterly said, noting that investors would see “who has done their work and who hasn’t.”
While defaults in the leveraged loan market have picked up this year from 2024, the pace remains low by historical standards, according to PitchBook LCD data. But concerns about the lack of due diligence in a frothy market are starting to mount.
“With [Tricolor] and First Brands, the problems of the credit market are starting to percolate into the general Wall Street psyche,” Milgram said. “Are we entering a period where those [CLO market’s] assumptions will be tested?”
The top-rated AAA tranches in CLOs have proven their mettle during prior market sell-offs and economic downturns, given how diversified the vehicles are. Investors said defaults would need to rise dramatically to begin to impair investors in even the lower-rated portions of the vehicles.
Money managers are nonetheless keenly aware of the problem that First Brands might cause the broader market.
Asset manager Silver Point this month began the marketing of its first euro CLO by highlighting one point in investor materials seen by the FT.
It said: “Silver Point has zero First Brands exposure.”
Roula Khalaf, Editor of the FT, selects her favourite stories in this weekly newsletter.
Venture Global is seeking to quell accusations from major energy clients that it plans to sell liquefied natural gas cargoes on spot markets rather than honouring supply contracts from its new export terminal in Louisiana.
The US LNG supplier wrote to clients on Thursday affirming its commitment to deliver on contractual obligations, after selling more than 100 cargoes from its Plaquemines facility before having declared it operational. Such a declaration triggers legal obligations to begin delivering on contracts.
The customers are fearing a repeat of Venture Global’s conduct when it launched its first facility, Calcasieu Pass, from which it sold more than 400 cargoes on spot markets before fulfilling deliveries to customers. The move has led to growing legal and financial pressure on the group after an international arbitration panel ruled last week that the company breached its obligations.
In a filing to US regulators last month, Venture Global requested a delay of its in-service date for Plaquemines by several months to the end of 2027, raising concerns among customers that the company could delay supplying cargoes to them as it did at its Calcasieu Pass facility.
In that case, the company declared force majeure on its contractual commitments in March 2023 on the grounds that the Calcasieu Pass facility’s power supply equipment needed repair, even though it was able to supply cargoes to the spot market amid a price surge following Russia’s invasion of Ukraine.
Spot markets are again priced far higher than long-term supply contracts would fetch.
Saul Kavonic, head of energy research at MST Marquee, said: “Venture Global stands to make over double the revenue by selling cargoes on the spot market compared to selling under their long-term contracts.”
The clients are so-called foundational customers, whose long-term contracts enable Venture Global to raise the money to build its LNG terminals.
Last week the International Chamber of Commerce found Venture Global breached its obligations to BP by failing to deliver cargoes from Calcasieu Pass. It now faces damages claims worth more than $1bn from the UK oil major, as well as four additional arbitration cases filed by customers that could lead to similar judgments.
Rating agency Fitch on Thursday revised its outlook on the company to “negative”, from “stable”, saying “any significant damages are likely to further pressure the company’s financial position in a period of elevated leverage”.
Venture Global’s request for an extension of its in-service date for Plaquemines, which the Federal Energy Regulatory Commission approved on Thursday, prompted two customers, Chevron and Orlen, a Poland-based energy company, to ask the regulators to intervene in the case.
Orlen, which is one of Plaquemines largest customers with a contract to buy 4mn tonnes of LNG a year, said it had “concerns regarding the intentions of Plaquemines parent company” in its submission to US energy regulators.
Shell, also a foundation customer, told the Financial Times it was “closely monitoring activities at the Plaquemines facility to ensure adherence to our contracted commercial operation date”.
When contacted for comment about its letter to customers, Venture Global said its recent filing to US regulators requesting a delay of its in-service date for Plaquemines to the end of 2027 would not change the date it would begin shipping cargos to long-term customers.
“Our request for an extension is a case of aligning our permits with our actual construction schedule,” it said. “To be clear, this request will have no impact on our expected commercial operations date, which remains unchanged from what has been communicated and agreed upon with our customers.”
Researchers at Embry-Riddle Aeronautical University and Brazil’s Instituto Tecnológico de Aeronáutica (ITA) will combine forces on one of the main challenges of electric aircraft — controlling the heat spikes they generate at takeoff.
The collaboration is supported by a $450,000 National Science Foundation International Research Experiences for Students (NSF IRES) grant.
“Both sides have been working on the heat management challenge, so there are some real synergies,” said Dr. Sandra Boetcher, the interim department chair and professor of Mechanical Engineering and principal investigator on the project. Boetcher is working with co-principal investigator Dr. Mark Ricklick, associate professor of Aerospace Engineering, as well as Brazilian colleagues Dr. Guilherme Borges Ribeiro and Dr. Elisan dos Santos Magalhães.
The collaboration is intended to offer hands-on research training to students, preparing them to tackle the issue of heat management on electric aircraft, considered key to reducing the aviation industry’s carbon footprint. The project will involve three cohorts of five Embry-Riddle students over the next three years spending eight to ten weeks between May and August in Brazil at ITA.
Boetcher said the heat management research that she and Ricklick undertake tends to be fundamental, developing prototypes, for example, that can be further tested. Similar research out of ITA, which is affiliated with the Brazilian Air Force and the Brazilian multinational aerospace corporation Embraer, tends to be applied.
One of the main technologies the researchers from both countries are exploring relates to phase-change materials, which convert from a solid to a liquid at certain temperatures and are capable of absorbing large amounts of heat during the process.
Drs. Sandra Boetcher and Mark Ricklick, standing in front of an aircraft turbine, received a $450,000 NSF grant to offer a student research collaboration with Brazilian colleagues on heat management of electric aircraft. (Photo: Sandra Boetcher)In a phase-change process, energy, in this case heat, is expended on overcoming the molecular forces holding a solid structure together, changing the material to a liquid. No temperature rise occurs during the change. This happens in everyday phase changes, Boetcher explained.
“It’s like you’re melting an ice cube,” she said. “The ice cube is melting, but the temperature stays the same,” until the ice cube becomes water and the water’s temperature starts to climb.
The phase-change materials being investigated by the researchers capitalize on the phenomenon and can be applied as a slab under an aircraft’s electrical circuit to keep it under a certain temperature.
Modeling to optimize the performance of phase-change materials with computer simulations can be time-consuming, with computational fluid dynamics problems taking as long as two weeks to solve.
Magalhães brings coding expertise that could “speed up the process of solving the problem,” Boetcher said.
The researchers will also look at other technologies to manage heat in electric aircraft, including ones that could provide active cooling rather than passive heat absorption.
Boetcher said she thinks the students who travel to Brazil will benefit deeply, even apart from participating in the technological innovations that could result.
“It’s dealing with other cultures, with other collaborators, how they view things, how they operate, how they work,” she said. “There’s a lot of maturing when you get to have these opportunities abroad.”
Dr. Jeremy Ernst, vice president for research and doctoral programs, further emphasized the value of the collaboration.
“The IRES program is impactful in creating research exposure and authentic international experience,” Ernst said. “The work led by Dr. Boetcher and Dr. Ricklick is of high value to students, offering enhanced cultural immersion in Brazil within its rich aviation and aerospace environment. This experience allows students to develop skills that are directly transferable to the global workforce.”
Vietnam’s upgrade to Emerging Market status by FTSE Russell is a green flag for global investors and a step towards greater financial market integration. The 2025-2027 reforms can translate into easier capital access and disclosure transparency for businesses looking at a long-term foothold in Vietnam.
FTSE Russell announced on October 7, 2025, that Vietnam will be upgraded from Frontier to Secondary Emerging Market (EM) status, from September 21, 2026, after a final review scheduled for March 2026. The decision comes after nearly seven years of gradual reform since Vietnam was first placed on the FTSE watchlist in 2018.
Vietnam’s upgrade to Secondary Emerging Market status places it alongside China, India, Indonesia, the Philippines, and Qatar. It ranks below Advanced Emerging Markets such as Thailand and Malaysia, and Developed Markets like Singapore.
Understanding the FTSE classification and upgrade process
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FTSE Russell’s Equity Country Classification Framework evaluates markets based on a set of quantitative and qualitative indicators that measure openness and regulatory quality.
The Secondary Emerging Market status hinges on countries satisfying these primary criteria:
Market accessibility for foreign investors;
Settlement and custody infrastructure;
Transaction transparency and liquidity; and
Market size, free float, and institutional participation.
Vietnam successfully met all these conditions and addressed many longstanding barriers that were limiting investor participation. The country addressed two critical technical barriers that previously prevented the upgrade, including:
Settlement cycle and pre-funding requirements
In November 2024, the Ministry of Finance issued Circular 68/2024/TT-BTC, which introduced the Non-Pre-funding Solution (NPS) model. Before, foreign institutional investors were required to fully pre-fund equity purchases before execution, a rule that discouraged global funds accustomed to T+2 settlement systems. Under the NPS, securities firms now bear the responsibility of assessing and managing payment risk under the contracts.
Failed trade processing mechanism
Vietnam implemented a mechanism for handling settlement failures to improve transparency in post-trade activities. It ensures the timely resolution of settlement failures and brings Vietnam’s back-office procedures closer to international standards.
Interim review and pending conditions
Although Vietnam has met the requirements for EM classification, the March 2026 interim review will evaluate one remaining area, which is direct access for global brokerage firms.
FTSE Russell noted that this is not a mandatory criterion for maintaining EM status, but it remains crucial for Vietnam’s index and for aiding participation by major global institutional investors.
Projected capital inflows and portfolio effects
The upgrade is expected to catalyze a lot of foreign capital inflows. Analysts have made various investment projections, some of which like:
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FTSE Russell estimates inflows of around US$6 billion from passive index trackers that replicate the FTSE Emerging Market Index;
The World Bank projects short-term inflows of approximately US$5 billion before and after the upgrade from passive and active investors, and long-term potential inflows could reach $25 billion by 2030; and
HSBC forecasts range from US$3.4 billion (active funds) to US$10.4 billion (total including passive funds).
Vietnam is expected to account for approximately 0.5 percent of the FTSE Emerging Market Index once the reclassification takes effect.
Active fund participation
According to HSBC, approximately 38 percent of Asia-focused funds and 30 percent of global emerging market funds already hold Vietnamese equities, which suggests that beyond passive index flows, Vietnam could attract new active fund allocations too.
Liquidity, valuation, and trading depth
Vietnam’s stock market has demonstrated strong liquidity in 2025. In July 2025, average daily trading volume reached over 1,422 million shares as average daily turnover reached VND 34,993 billion (US$1.32 billion). The market hit historic liquidity records with total trading value on the Ho Chi Minh City Stock Exchange (HOSE) as it approached VND 78.2 trillion (US$2.9 billion) in early August 2025. As of May 2025, Vietnam Exchange posted nearly US$18 billion in monthly trading value, overtaking Malaysia (US$12.1 billion) and Indonesia (US$15.3 billion)
Anticipation of the FTSE announcement has already influenced domestic equity performance. The VN-Index has risen from 1,100 points in April 2025 to nearly 1,700 points by October 2025, which is a 50 percent jump and a 33 percent year-to-date gain; thus, Vietnam has become the best-performing market in Southeast Asia.
HSBC analysts, however, caution that front-loading, the tendency of investors to buy in anticipation of future reclassification, may limit further short-term upside. Profit-taking could occur after the announcement, as observed in other markets following index upgrades. Nevertheless, most research expects active funds to disburse gradually between March and September 2026.
Domestic reforms enabling the upgrade
Vietnam’s reclassification is a cumulative result of regulatory and structural reforms that have improved its foreign access.
Central counterparty and post-trade reforms
The State Securities Commission (SSC) has given a roadmap to launch a central counterparty (CCP) system for Vietnam’s equity market by Q1 2027. Milestones on the way are:
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Q1-Q2 2026: SSC and the Vietnam Securities Depository and Clearing Corporation (VSDC) will issue a new circular to replace Circular 119/2020/TT-BTC on registration, custody, and settlement;
Q3 2025-Q1 2026: Establishment of a VSDC subsidiary to handle CCP functions;
Q3 2025-Q4 2026: Introduction of a revised accounting framework to replace Circular 89/2019/TT-BTC;
2026: IT system upgrades, staff training, and simulation testing; and
Q1 2027: Full-scale operation of the CCP.
CCP will help foreign institutional investors reduce currency risk during the payment cycle and provide safer mechanisms against payment risks.
Technology infrastructure modernization
Vietnam launched the KRX trading platform on May 5, 2025, in partnership with the Korea Exchange (KRX). The platform addresses several bottlenecks and expands derivative products available to investors with these new features:
Same-day trading (T+0) and short selling;
Faster settlement processing; and
Support for options contracts and CCP clearing.
Disclosure and transparency
From January 1, 2025, all VN30 companies (the 30 largest listed firms) have been required to publish disclosures in Vietnamese as well as English. By the end of 2026, all approximately 2,000 listed and registered trading companies must complete the transition to English-language disclosures. Currently, only about 25-30 percent of listed companies provide complete English disclosures.
Other reforms
Other transformative reforms include:
Removal of pre-funding obligations: As noted above, Circular 68/2024/TT-BTC eliminated the full pre-funding requirement for foreign investors.
Foreign ownership liberalization: Decree 245/2025/ND-CP, issued on September 11, 2025, removed provisions that allowed listed companies to set foreign ownership limits below the legal maximum. All public companies must now publicly disclose their maximum allowable foreign ownership ratio within 12 months of the decree’s coming into force.
Simplified trading code issuance: Foreign investors can now receive an electronic securities trading code (ESTC) and commence trading immediately without submitting physical paperwork.
Accelerated IPO and listing timelines: The period for securities to be traded after listing approval was shortened from 90 days to 30 days, and the overall listing process was reduced by 3-6 months.
Remaining reform gaps
Despite its upgrade, Vietnam continues to face structural challenges that must be addressed to sustain investor confidence.
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Currency convertibility: The Vietnamese Dong is not freely convertible and cannot be remitted overseas. Foreign exchange transactions remain subject to State Bank of Vietnam (SBV) controls.
Global broker access: The March 2026 interim review will specifically assess progress in this area.
ESG disclosure: Only 25 percent of listed companies publish environmental, social, and governance (ESG) reports, most without external assurance.
Integration with global finance
The FTSE upgrade is a part of a series of efforts Vietnam is taking for global financial integration and capital market openness. Vietnam’s Finance Minister Nguyen Van Thang stated that “the official recognition and upgrade of Vietnam’s securities market is clear evidence of the country’s sound development path and its growing capacity to integrate deeply into the global financial system”.
The government has set an ambitious target of 8 percent GDP growth for 2025 and aims to achieve double-digit growth between 2026 and 2030. The present roadmap for Vietnam’s stock market development goes up to 2030. The market can aim for medium-term targets for MSCI Emerging Market upgrade between 2026 and 2027 and can have long-term goals for FTSE Advanced Emerging Market status by 2029 and 2030.
Monetary and currency management
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Vietnam’s GDP growth recorded an 8.23 percent year-on-year rise in Q3 2025, the fastest since 2022. The Purchasing Manager’s Index was 50.4 in September 2025, and total trade volume reached US$680 billion, with exports up 14.8 percent to US$262.44 billion.
The SBV maintains an inflation target of 4.5 percent for 2025. As of mid-year, consumer prices rose 3.27 percent, and core inflation stood at 3.16 percent. Refinancing rates remain at 4.5 percent (at an accommodative policy stance).
The Federal Reserve’s rate cuts in 2025 have provided room for Vietnam to maintain low domestic interest rates without pressuring the dong. As we noted, the Vietnamese Dong is not freely convertible as foreign exchange transactions still are subject to SBV controls.
Vietnam’s sovereign credit ratings remain below investment grade but stable:
Standard & Poor‘s BB+ with stable outlook (affirmed August 2025);
Fitch’s BB+ with stable outlook (affirmed June 2025); and
Moody’s: Ba2 with stable outlook (unchanged since 2022).
The EM reclassification could fuel investor appetite for Vietnamese sovereign bonds, which could potentially lower long-term borrowing costs. Vietnam now stands at the threshold of deeper global integration. Despite global headwinds, Vietnam’s domestic reforms and foreign investors’ belief in its robustness can provide a much-needed boost for double-digit growth.
Vietnam Briefing is one of five regional publications under the Asia Briefing brand. It is supported by Dezan Shira & Associates, a pan-Asia, multi-disciplinary professional services firm that assists foreign investors throughout Asia, including through offices in Hanoi, Ho Chi Minh City, and Da Nang in Vietnam. Dezan Shira & Associates also maintains offices or has alliance partners assisting foreign investors in China, Hong Kong SAR, Indonesia, Singapore, Malaysia, Mongolia, Dubai (UAE),Japan, South Korea, Nepal, The Philippines, Sri Lanka, Thailand, Italy, Germany, Bangladesh, Australia, United States, and United Kingdom and Ireland.
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