Category: 3. Business

  • FDA rejects Capricor’s Duchenne cell therapy

    FDA rejects Capricor’s Duchenne cell therapy

    Adam Feuerstein is a senior writer and biotech columnist, reporting on the crossroads of drug development, business, Wall Street, and biotechnology. He is also a co-host of the weekly biotech podcast The Readout Loud and author of the newsletter Adam’s Biotech Scorecard. You can reach Adam on Signal at stataf.54.

    The Food and Drug Administration rejected a marketing application from Capricor Therapeutics for a cell therapy to treat Duchenne muscular dystrophy, the company said Friday. 

    In its letter to Capricor, the FDA said the company’s application “does not meet the statutory requirement for substantial evidence of effectiveness” and requested additional clinical data, the company said. 

    Capricor submitted a marketing application to the FDA at the end of December. Its off-the-shelf cell therapy, called deramiocel, would have been the first treatment cleared specifically for the cardiomyopathy, a serious heart condition, that is associated with Duchenne. It could have also been used alongside other Duchenne drugs or gene therapies. 

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  • Hailey Welch reportedly sells X account after viral fame as Hawk Tuah Girl

    Hailey Welch reportedly sells X account after viral fame as Hawk Tuah Girl

    Hailey Welch, widely known as the “Hawk Tuah Girl” after her viral rise to internet fame in 2024, is back in the spotlight—this time for reportedly selling her X (formerly Twitter) account. The page, once personal and linked to Welch, has now been rebranded as “Up Only Memes,” with a new profile image and direction, catching the attention of her nearly 400,000 followers.

    The sudden transformation raised questions, especially after two new tweets appeared on July 9. One was a playful reference to memes, while the other cryptically stated, “What the helly,” alongside a screenshot of someone offering $325,000 to purchase an X account. It remains unclear whether these posts came from Welch as parting shots or from a new owner signaling a shift in content.

    Meanwhile, the account—which now boasts nearly 400,000 followers—shows only four tweets. Of those, two date back to Welch’s time managing the page (July 27, 2024, and March 28, 2025), while the other two—posted on July 9—suggest a new and possibly chaotic direction. The disappearance of previous tweets has fueled theories and confusion among longtime fans.

    Social media users wasted no time reacting. Some joked that Welch might be “paying legal bills,” while others saw it as either a smart business move or a digital stunt. “She might be the best one-hit wonder of all time,” one user commented. Another called it, “the greatest scam.”

    Whether this is a strategic exit, a brand pivot, or something else entirely, Welch’s digital footprint continues to spark viral interest and online debate—proving once again that internet fame rarely fades quietly.


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  • Jamie Dimon has a blunt message for Europe: ‘You’re losing’

    Jamie Dimon has a blunt message for Europe: ‘You’re losing’

    Key Points

    • Jamie Dimon told an event in Ireland on Thursday that Europe was “losing” on competitiveness and lacked the kind of global, successful corporations common in the U.S.
    • The JPMorgan Chase boss also told an event in Ireland that there was “complacency in the markets” around U.S. tariffs and rates.
    • Dimon said he saw a 40-50% chance that the Federal Reserve would need to raise interest rates to tackle inflation, against market pricing of around a 20% chance.

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  • Decision to drop zonal pricing for GB electricity generation welcomed

    Decision to drop zonal pricing for GB electricity generation welcomed

    The conclusion means that the government does not intend to introduce zonal pricing and instead will implement an ambitious approach to reformed national pricing – a cohesive package of reforms to improve the effectiveness of the national pricing model. This package sets out to deliver a more strategic and co-ordinated approach to the energy system, provide strong signals for efficient siting of new assets, and improve overall operational efficiency, whilst also increasing stability and certainty for investors.

    Ronan Lambe, energy projects expert at Pinsent Masons, said: “Stakeholders warned that the introduction of zonal pricing would cause significant investment risk, creating uncertainty and raised costs. We have already seen the potential impact of these proposed changes to create such uncertainty across a variety of deals, particularly where electricity prices need to be secured across an extended period of time.”

    The government hopes that reformed national pricing will provide certainty for investors, aligning network and connection charges with strategic planning to support long term investment. The strategy also aims to provide fairness for consumers. Consumers will continue to benefit from uniform national pricing, with locational costs absorbed through broader market mechanisms like contracts for difference (CfDs) and the capacity market. It is also hoped that reformatted national pricing will provide lower costs, simplifying the investment processes and better siting reduce costs, helping to lower consumer bills

    Gabby Greenslade, energy projects lawyer at Pinsent Masons, said: “The reformed national pricing approach emphasises stability and resilience – both crucial to navigating the energy transition by offering investors and consumers the predictability required to plan confidently.”

    At the core of the reforms will be the strategic spatial energy plan (SSEP), which will guide co-ordinated planning and proactive network investment. It will map optimal locations and types of energy infrastructure to support the UK’s clean energy transition, aiming to reduce delays and costs in connecting new projects to the grid. The plan will work to coordinate important levers such as planning reform, seabed leasing, network development, and connection and charging reforms.

    The first version of the SSEP, covering electricity and hydrogen generation and storage, is expected in 2026 and “will assess infrastructure needs regionally, providing clarity to industry while allowing market competition to determine the best projects to pursue”,  said Lambe.

    Further upcoming actions include the publication of a reformed national pricing delivery plan, outlining the design and implementation roadmap – expected later this year. The government is expected to release the final review of electricity market arrangements (REMA) analysis, including a full cost-benefit analysis of wholesale market reform options later this year.

    By the end of 2026, a collaboration between National Energy System Operator (NESO) and the government is expected in order to deliver the SSEP. The government will also work with Ofgem to advance reforms to transmission network use of system (TNUoS) and connection charges. Additionally, a consultation on balancing reform and completing NESO’s constraints collaboration project is also expected by the end of the year.

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  • How Iconiq, wealth firm backed by Zuckerberg, brings rich donors together

    How Iconiq, wealth firm backed by Zuckerberg, brings rich donors together

    Meta CEO Mark Zuckerberg and Square CEO Jack Dorsey.

    Manuel Orbegozo | Handout | Reuters

    A version of this article first appeared in CNBC’s Inside Wealth newsletter with Robert Frank, a weekly guide to the high-net-worth investor and consumer. Sign up to receive future editions, straight to your inbox.

    Even as tax changes may reduce giving by the wealthy, a leading investment firm is pioneering a new model of philanthropy that could spur big donors to act now.

    Iconiq Capital, which started in Silicon Valley with clients like Mark Zuckerberg and Jack Dorsey, has created collaborative philanthropy funds to jump-start giving. These so-called co-labs pool clients’ capital to make multiyear grants to a group of nonprofits focused on causes like climate equity and economic mobility. 

    The most recent co-lab targets youth mental health and has raised $112 million from 10 families, with a goal of $200 million by the end of the year. Iconiq Impact, the firm’s charitable giving arm, has advised on nearly $900 million in grants over six years, mostly through the co-labs.

    Iconiq Impact head Matti Navellou joined the San Francisco-based firm from UNICEF six years ago. She built the co-lab program after hearing that clients wanted to learn about philanthropy from their peers.

    “It is a really lonely journey, and it’s hard to find peers at the same wealth level who are struggling with the same type of challenges,” she said. “How do you navigate the amount of people constantly pitching you? And how do you know where to focus?”

    The nonprofit sector’s woes are compounded by President Donald Trump’s tax bill, which reduces tax incentives for wealthy donors and makes steep cuts to social safety net programs. Nonprofit groups, including the 30,000-member strong National Council of Nonprofits, said charities will have fewer dollars at their disposal while their services are more needed.

    Navellou said charitable giving is more crucial than ever due to slashed federal funding. 

    “There are so many areas where, truly, philanthropy can move the needle right now, and so this structure that has been set up is problematic because it doesn’t actually incentivize accountability for spending that money for what it is designed for, which is funding nonprofits,” said Navellou. “We aim to influence the faster movement of dollars out the door.”

    Time is of the essence, but most Iconiq clients are busy founders who have little time to focus on philanthropy and have yet to build foundations, Navellou said. Foundations aren’t necessarily built for speed either, she said, as they are only required to donate 5% a year. Donor-advised funds are a popular low-effort option, but they aren’t obligated to disburse funds to charity.

    The co-labs allow clients to direct funds to charities quicker and with less effort. Iconiq develops a “portfolio” of charities in concert with clients after a series of in-person and Zoom gatherings with fellow funders and outside experts on causes of interest. After weeks of conversations, Iconiq develops the “portfolio” with the funders’ blessing and takes care of the rest.

    “What this does is it enables them to just move money much faster when they are in that time period of their life running companies,” Navellou said. 

    Matti Navellou, head of ICONIQ Impact, speaks with donors at the Ocean Co-Lab Community Retreat in Monterey, CA.

    Courtesy of Matti Navellou

    Getting donors to trust not only Iconiq but also the charities, rather than micromanaging how the funds are allocated, is key to the process, she said. The multiyear, unrestricted grants allow charity leaders to focus on the work rather than the fundraising, she added. 

    Bill Smith, founder and CEO of grantee Inseparable, said flexible funding allows nonprofits to adapt to a volatile policy climate. Inseparable is one of 25 nonprofits in the youth mental health co-lab, receiving about $1.3 million a year for five years starting this past December.

    “One of the hardest things when you’re running an organization, especially an advocacy organization, where we have changing circumstances with different administrations and what’s going on in states all over the country — the flexibility of having unrestricted money lets us go where we need to go and do what we need to do without constraints from a funder,” he said.

    Looking forward, Navellou said she wants to scale Iconiq Impact’s giving, which is made easier with collaborative contributions. Donors who aren’t Iconiq clients are welcome to participate in the co-labs, but funders are generally required to donate a single-digit million sum annually over three to five years, she said. 

    After Iconiq’s charity portfolios are designed, they are “open source,” she said, meaning other donors can follow on with commitments of as little as $250,000 a year. It’s convenient for younger entrepreneurs who want to dip their toes in philanthropy, she said.

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    The great wealth transfer may be promising for philanthropy, Navellou said. She has noticed that the young adult children of Iconiq clients are quicker to act and care more about measurable impact rather than specific causes.

    “There’s certainly a young cohort that do think about philanthropy differently, and I would say, are much more impatient around changing things and leveraging that capital in different ways, including through impact investing,” she said. “And I’d say they’re also issue agnostic, which is really interesting. They often will ask questions around data and letting the data inform and guide what they do, rather than coming to the table and saying, ‘I really want to move the needle on this issue.’”

    Women are expected to receive about 70% of the $124 trillion that will pass down over the next 25 years, according to Cerulli Associates. This also bodes well for charitable giving, Navellou said. 

    “What we’ve seen anecdotally, although there is data backing this as well, is that women tend to be more generous,” she said. “One area that’s really exciting is just a lot more female led philanthropy. We’re seeing that, and we’re really excited to build on that momentum that we’re seeing.”

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  • Middlesbrough food waste bins rollout on track, council says

    Middlesbrough food waste bins rollout on track, council says

    A council’s plans to introduce extra food waste collections are making “good progress”, after a previous garden waste rollout was labelled a “calamity”.

    Middlesbrough Council said the scheme to introduce free food waste bins in April 2026 was on track, with about 50,000 food bins set to be delivered to residents.

    A previous introduction of a new garden waste service in the town in spring 2024 saw issues arise over distribution problems.

    The council’s executive member for environment and sustainability, Peter Gavigan, said a fleet of vehicles had also been obtained for the new service.

    Labour councillor Gavigan said in a report: “We have procured our fleet of vehicles, designed our collection rounds and are currently working with our procurement colleagues to procure a company to deliver approximately 50,000 caddies to domestic properties across the town.”

    The food caddie bins are being introduced as part of the government’s Simpler Recycling scheme, which aims to create great consistency in recycled items around the country.

    As well as food waste pick-ups beginning from April 2026, existing recycling collections will change.

    Middlesbrough Council’s director of environment and community services Geoff Field told the Local Democracy Reporting Service in February the town would no longer put their recycling in one bin, after stating it was one of the worst in the country for recycling.

    “Everyone will be getting a different receptacle sometime in 2026 to collect that paper and cardboard separately to the other recycling,” he said.

    Gavigan’s report added that the council was awaiting approval to go weekly with recycling collections in 2026 to ensure they conformed with the regulations introduced by the Department for Environment, Food and Rural Affairs (Defra).

    Middlesbrough’s garden waste collection currently stood at 20,129 subscribers with a total bin count of 22,692 bins at residential properties, generating about £856,420, Gavigan said.

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  • Levi Strauss shares jump after raising forecasts on strong global denim demand

    Levi Strauss shares jump after raising forecasts on strong global denim demand

    (Reuters) -Levi Strauss shares surged more than 7% in premarket trading on Friday after the denim maker raised its annual revenue and profit forecasts, counting on robust demand at its stores and website to offset a margin hit from U.S. tariffs.

    The company has been investing in its direct-to-consumer-first strategy and focusing on its core denim lifestyle products, which drove second-quarter sales and profit beat.

    Levi’s results beat was “impressive”, said Dana Telsey, analyst at Telsey Advisory Group. The raised forecast was also encouraging as it now includes an estimated impact from 30% tariffs on China and 10% duties on other countries, Telsey added.

    The denim maker said it would counter President Donald Trump’s tariffs on imports into the U.S. by diversifying its supply chain to further reduce dependence on China and source from countries such as Bangladesh and Cambodia.

    To be sure, the updated forecast does not account for Trump’s proposed 36% tariff rate on Cambodia and a 35% levy on U.S. imports from Bangladesh, which are set to go into effect on August 1.

    About 60% of Levi’s revenue came from outside of the U.S., which grew 10% in the second quarter, led by Europe. Revenue from the U.S. grew 7%.

    The company’s focus on denim dresses and skirts and growth in its women’s apparel and Beyond Yoga brand have led to increased purchases from younger customers, said J.P.Morgan analyst Matthew Boss in a note.

    Levi’s stock trades at 14.92 times analysts’ estimates for the company’s earnings for the next 12 months, compared with 20.32 for Ralph Lauren and 8.46 for Abercrombie & Fitch, according to LSEG data.

    (Reporting by Juveria Tabassum in Bengaluru; Editing by Leroy Leo)

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  • Malaysia’s palm oil stocks hit 18-month high in June on surprise exports slump

    Malaysia’s palm oil stocks hit 18-month high in June on surprise exports slump

    Malaysia’s palm oil stocks jumped to their highest in 18 months in June, as an unexpected drop in exports outweighed the slump in production and a spike in domestic consumption, data from the industry regulator showed on Thursday.

    The rise in inventories in the world’s second-biggest producer of tropical oil could weigh benchmark Malaysian futures FCPO1!, which were trading near their highest in nearly three months.

    Palm oil inventories at the end of June rose 2.41% month-on-month, the fourth consecutive monthly increase, to 2.03 million metric tons, the highest since December 2023, data from the Malaysian Palm Oil Board (MPOB) showed.

    Palm oil exports plunged 10.52% to 1.26 million tons, while crude palm oil production fell for the first time in four months in June, dropping 4.48% from May to 1.69 million tons, MPOB said.
    Domestic palm oil consumption last month jumped 44% from May to 455,150.

    A Reuters survey had forecast June inventories at 1.99 million tons, with output seen at 1.7 million tons and exports at 1.45 million tons.

    Malaysia’s palm oil stocks jumped to their highest level in 18 months in June, as an unexpected big drop in exports offset a reduction in local production and a surge in local consumption.

    The MPOB report is slightly bearish for palm oil, as the market wasn’t expecting a big drop in exports, which lifted stock levels above 2 million tons, said Anilkumar Bagani, research head of Mumbai-based vegetable oil broker Sunvin Group.

    A few cargoes loaded in June might actually get dispatched in July because of port congestion in India and as Malaysia has lowered the export duty for July shipments, said a New Delhi-based dealer with a global trade house.

    Malaysia has lowered its July crude palm oil reference price, a change that brought down the export duty to 8.5% from 9.5% in June.

    “We could see a jump in July exports due to the roll-over of cargoes from June. Besides, some exporters might advance August shipments to July because of the lower export duty,” the dealer said.

    Malaysia’s palm oil exports in the first ten days of July rose 12% compared to the first ten days of June, independent inspection company AmSpec Agri Malaysia said on Thursday.
    Source: Reuters


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  • UK: FCA launches Investment Advice Assessment Tool

    UK: FCA launches Investment Advice Assessment Tool

    United KingdomGlobal

    United KingdomGlobal

    United KingdomGlobal

    The FCA has launched its Investment Advice Assessment Tool (“IAAT”), which sets the standards firms should apply when assessing the suitability of its advice, disclosures to consumers and compliance with Principle 12 and the Consumer Duty

    Why should I read this?

    • The FCA has introduced the IAAT, an Excel-based framework designed to assist firms in evaluating the suitability of their advice[1], the adequacy of client disclosures, and compliance with Principle 12 and the Consumer Duty[2]. Firms can access the tool here IAAT and the instructions for use here instructions.
    • Although the FCA describes the tool as guidance, it incorporates the IAAT into its supervision of firms and potential enforcement. This implies that the IAAT represents the standards the FCA expects firms to meet when assessing the suitability of advice, the quality of disclosures provided to consumers, and compliance with obligations under Principle 12 and the Consumer Duty.
    • Firms that do not implement the IAAT into their practices or adhere to its standards may encounter challenges in justifying their advice in the event of a complaint or FCA investigation.

    What should I do now?

    • Review and align with IAAT Standards: Firms should review the IAAT tool to strategically evaluate their advice and disclosures, ensuring they align with the required standards and satisfy Principle 12 and the Consumer Duty. If they do not, firms should amend their processes, systems, and controls to meet the outcome-focused standards.
    • Ensure full and complete information gathering: Firms must ensure that all relevant information is gathered and documented, forming the basis for the advice given. If there is a material information gap, firms should obtain this before providing advice. This is a consistent area where firms can let themselves down, particularly in on going relationships with clients where there is a failure to update changes in circumstances.
    • Embed IAAT into complaint handling and past business reviews practices: Firms should integrate the IAAT tool, or its standards, into their complaint handling and past business review processes. The FCA expects firms to use the IAAT tool to assess the suitability of advice and the extent of disclosures when considering complaints about past advice or conducting past business reviews. If failures are identified or documents are absent, firms should proactively consider offering redress where the advice is deemed to be unsuitable.
    • Anticipate FOS adoption of the principles of IAAT: Although not publicised, the Financial Ombudsman Service (“FOS”) may adopt this tool, or aspects of it, when considering investment advice based complaints in line with its obligation to take into account relevant regulators rules, guidance and standards. The FOS may also critically analyse whether the firms have completed the IAAT correctly, as the FOS has with some decisions relating to pensions and firms’ completion of the defined benefit advice assessment tool. Firms should evaluate whether they have satisfied the IAAT requirements in the context of ongoing and new FOS complaints and, if not, consider whether it can justify this to the FOS.
    • Prepare for CMC activity: We anticipate Claims Management Companies (“CMCs”) using aspects of the tool when considering complaints and claims on behalf of their clients, leveraging any gaps as a basis for a complaint or claim against a firm. If such complaints are received, firms should consider whether the claim is properly made out. While a gap in the IAAT could give rise to a regulatory failing, it does not always follow that this has caused loss or detriment or gives rise to a legal basis for a claim against the firm.

    What else do I need to know about the FCA’s IAAT?

    • Firms can use the IAAT to assess the suitability of their investment advice and the adequacy of client disclosures for advice given after 3 January 2018, as well as compliance with the Consumer Duty from when it came into force on 1 August 2023.
    • The tool should not be used for the consideration of retirement income or defined benefit transfer advice, for which there are separate tools.

     

    [1]  For advice after 3 January 2018

    [2]   For advice after 31 July 2023 for products and services on sale or available for renewal on or after this date, and effective from 31 July 2024 for products and services that are no longer on sale or available for renewal on or after this date.

    The materials on the Eversheds Sutherland website are for general information purposes only and do not constitute legal advice. While reasonable care is taken to ensure accuracy, the materials may not reflect the most current legal developments. Eversheds Sutherland disclaims liability for actions taken based on the materials. Always consult a qualified lawyer for specific legal matters. To view the full disclaimer, see our Terms and Conditions or Disclaimer section in the footer.

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  • Wyoming’s first new coal mine in decades to extract rare earths

    Wyoming’s first new coal mine in decades to extract rare earths

    CHEYENNE, Wyo. — The developer of what would be the first new coal mine in Wyoming in decades plans to process the fossil fuel to extract hard-to-get metals that are crucial for tech products and military hardware.

    Energy Secretary Chris Wright, former West Virginia U.S. Sen. Joe Manchin, Wyoming Gov. Mark Gordon, and Wyoming’s congressional delegation are on the VIP list for a groundbreaking ceremony Friday at the Ramaco Resources, Inc., Brook Mine outside Ranchester in far northern Wyoming.

    Rare earth elements are a family of 17 metallic elements with unusual properties that make them useful for specific applications. Neodymium and dysprosium are used in the permanent magnets of wind turbines, lanthanum in electric and hybrid car batteries.

    Yttrium and terbium have critical military uses, including in targeting devices.

    China supplies almost 90% of the world’s rare earths. Concern about continued access to the substances has been a focus of recent negotiations between China and the U.S., and led the Trump administration to try to encourage more production domestically.

    Rare earths aren’t especially rare but so scattered they are difficult to bring together in useful quantities. Currently the only U.S. rare earths mine is at Mountain Pass in California.

    Analysis by U.S. national laboratories show the Brook Mine coal contains valuable quantities of the rare earths neodymium, praseodymium, dysprosium and terbium, as well as the critical minerals gallium, scandium and germanium, according to a Ramaco letter to shareholders on July 1.

    “We would intend to mine it here in Wyoming, process it here in Wyoming and sell it to domestic customers including the government,” Ramaco CEO Randall Atkins said Thursday.

    Manchin, who left office in January after not seeking re-election, joined the Ramaco board in April.

    No new Wyoming coal mine has opened in 50 years. Wyoming’s coal industry instead has shrunk substantially since its peak over a decade ago, troubled as utilities switch to renewable energy and power plants fueled by cheaper natural gas.

    The Brook Mine, stalled in part by landowners worried about groundwater depletion, has been in the works for over a decade. Atkins originally envisioned it as a source of subbituminous power plant fuel, much like Wyoming’s massive open-pit mines that supply about 40% of the nation’s coal.

    A public company with metallurgical coal mines in Appalachia, Ramaco in recent years received Department of Energy grants to develop coal into carbon-based products such as carbon fiber. This year, it got a $6.1 million grant from Wyoming to build a rare earth and critical minerals processing plant.

    A consultant report released this week found that fully developing the mine and processing plant would cost around $500 million, a sum that could be recovered in five years if the rare earths can be extracted and sold. Ramaco also would sell the processed coal as fuel, Atkins said.

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